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Neutropenic disorder

MedGen UID:
18030
•Concept ID:
C0027947
•
Disease or Syndrome
Synonyms: Neutropenia; Neutropenias
SNOMED CT: Neutropenic disorder (303011007)

Definition

A decrease in the number of NEUTROPHILS found in the blood. [from MeSH]

Professional guidelines

PubMed

Diagnosis and Treatment of Myelodysplastic Syndromes: A Review.
Sekeres MA, Taylor J
JAMA 2022 Sep 6;328(9):872-880. doi: 10.1001/jama.2022.14578. PMID: 36066514
Clinical Practice Guideline for the Management of Asymptomatic Bacteriuria: 2019 Update by the Infectious Diseases Society of America.
Nicolle LE, Gupta K, Bradley SF, Colgan R, DeMuri GP, Drekonja D, Eckert LO, Geerlings SE, Köves B, Hooton TM, Juthani-Mehta M, Knight SL, Saint S, Schaeffer AJ, Trautner B, Wullt B, Siemieniuk R
Clin Infect Dis 2019 May 2;68(10):e83-e110. doi: 10.1093/cid/ciy1121. PMID: 30895288
Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the infectious diseases society of america.
Freifeld AG, Bow EJ, Sepkowitz KA, Boeckh MJ, Ito JI, Mullen CA, Raad II, Rolston KV, Young JA, Wingard JR; Infectious Diseases Society of America
Clin Infect Dis 2011 Feb 15;52(4):e56-93. doi: 10.1093/cid/cir073. PMID: 21258094

Recent clinical studies

Diagnosis

Pure White Cell Aplasia Complicated by Systemic Sclerosis with Accompanying Scleroderma Renal Crisis.
Suzuki E, Oda R, Kanno T, Kimura S, Saito Y, Kanbayashi H, Matsuda S, Migita K
Intern Med 2022 Jun 15;61(12):1907-1912. Epub 2021 Nov 20 doi: 10.2169/internalmedicine.8436-21. PMID: 34803102Free PMC Article
Clostridium septicum myonecrosis in congenital neutropenia.
Barnes C, Gerstle JT, Freedman MH, Carcao MD
Pediatrics 2004 Dec;114(6):e757-60. doi: 10.1542/peds.2004-0124. PMID: 15574607

Therapy

Pure White Cell Aplasia Complicated by Systemic Sclerosis with Accompanying Scleroderma Renal Crisis.
Suzuki E, Oda R, Kanno T, Kimura S, Saito Y, Kanbayashi H, Matsuda S, Migita K
Intern Med 2022 Jun 15;61(12):1907-1912. Epub 2021 Nov 20 doi: 10.2169/internalmedicine.8436-21. PMID: 34803102Free PMC Article
Clostridium septicum myonecrosis in congenital neutropenia.
Barnes C, Gerstle JT, Freedman MH, Carcao MD
Pediatrics 2004 Dec;114(6):e757-60. doi: 10.1542/peds.2004-0124. PMID: 15574607
Neutropenia and thrombocytopenia: antibodies directed against circulating neutrophils and bone marrow myeloid progenitor cells (CFU-C).
Kirshner JJ, Goldberg J, Dinter R, Boxer LA
Am J Med Sci 1986 Jan;291(1):51-5. doi: 10.1097/00000441-198601000-00010. PMID: 3942159

Prognosis

Clostridium septicum myonecrosis in congenital neutropenia.
Barnes C, Gerstle JT, Freedman MH, Carcao MD
Pediatrics 2004 Dec;114(6):e757-60. doi: 10.1542/peds.2004-0124. PMID: 15574607
Neutropenia and thrombocytopenia: antibodies directed against circulating neutrophils and bone marrow myeloid progenitor cells (CFU-C).
Kirshner JJ, Goldberg J, Dinter R, Boxer LA
Am J Med Sci 1986 Jan;291(1):51-5. doi: 10.1097/00000441-198601000-00010. PMID: 3942159

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