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Dextro-looped transposition of the great arteries

MedGen UID:
1812310
•Concept ID:
C5671327
•
Congenital Abnormality
Synonyms: Dextro Looped Transposition of the Great Arteries; Dextro TGA; Dextro-Looped Transposition of the Great Arteries; Dextro-TGA; Dextro-TGAs; Dextrotransposition of Great Vessels; Great Vessels Dextrotransposition; Great Vessels Dextrotranspositions
Modes of inheritance:
Non-Mendelian inheritance
MedGen UID:
109109
•Concept ID:
C0600599
•
Genetic Function
Source: Orphanet
A mode of inheritance that depends on genetic determinants in more than one gene.
Not genetically inherited
MedGen UID:
988794
•Concept ID:
CN307044
•
Finding
Source: Orphanet
clinical entity without genetic inheritance.
See: This record
Non-Mendelian inheritance (Orphanet)
Not genetically inherited (Orphanet)
 
Monarch Initiative: MONDO:0019443
Orphanet: ORPHA860

Definition

Congenitally uncorrected transposition of the great arteries (congenitally uncorrected TGA), also referred to as complete transposition, is a congenital cardiac malformation characterized by atrioventricular concordance and ventriculoarterial (VA) discordance. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDextro-looped transposition of the great arteries

Professional guidelines

PubMed

Management of congenitally corrected transposition from fetal diagnosis to adulthood.
Kowalik E
Expert Rev Cardiovasc Ther 2023 Jun;21(6):389-396. Epub 2023 May 9 doi: 10.1080/14779072.2023.2211264. PMID: 37143366
Assessment and management of heart failure in the systemic right ventricle.
Carazo M, Andrade L, Kim Y, Wilson W, Wu FM
Heart Fail Rev 2020 Jul;25(4):609-621. doi: 10.1007/s10741-020-09914-2. PMID: 31970551
Management of the Adult Patient With Congenitally Corrected Transposition: Challenges and Uncertainties.
Connolly HM, Miranda WR, Egbe AC, Warnes CA
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2019;22:61-65. doi: 10.1053/j.pcsu.2019.02.006. PMID: 31027566

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