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Anti-CARP VIII antibody

MedGen UID:
1813972
•Concept ID:
C5551489
•
Finding
Synonyms: Anti CARPVIII antibody; Anti-carbonic anhydrase-related protein VIII antibody
 
HPO: HP:5000004

Definition

The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Carbonic anhydrase-related protein VIII (CARPVIII). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnti-CARP VIII antibody

Recent clinical studies

Diagnosis

Paraneoplastic cerebellar degeneration in a patient with breast cancer associated with carbonic anhydrase-related protein VIII autoantibodies.
Prevezianou A, Tzartos JS, Dagklis IE, Bentenidi E, Angelopoulos P, Bostantjopoulou S
J Neuroimmunol 2020 Jul 15;344:577242. Epub 2020 Apr 14 doi: 10.1016/j.jneuroim.2020.577242. PMID: 32325285
'Medusa-head ataxia': the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 1: Anti-mGluR1, anti-Homer-3, anti-Sj/ITPR1 and anti-CARP VIII.
Jarius S, Wildemann B
J Neuroinflammation 2015 Sep 17;12:166. doi: 10.1186/s12974-015-0356-y. PMID: 26377085Free PMC Article

Prognosis

'Medusa-head ataxia': the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 1: Anti-mGluR1, anti-Homer-3, anti-Sj/ITPR1 and anti-CARP VIII.
Jarius S, Wildemann B
J Neuroinflammation 2015 Sep 17;12:166. doi: 10.1186/s12974-015-0356-y. PMID: 26377085Free PMC Article

Clinical prediction guides

'Medusa-head ataxia': the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 1: Anti-mGluR1, anti-Homer-3, anti-Sj/ITPR1 and anti-CARP VIII.
Jarius S, Wildemann B
J Neuroinflammation 2015 Sep 17;12:166. doi: 10.1186/s12974-015-0356-y. PMID: 26377085Free PMC Article

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