U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Absent second fingernail

MedGen UID:
1814103
•Concept ID:
C5558364
•
Anatomical Abnormality
HPO: HP:0033975

Definition

Absence of the fingernail of the index (second) finger. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbsent second fingernail

Professional guidelines

PubMed

Chemical matricectomy with 10% sodium hydroxide for the treatment of ingrowing toenails.
Ozdemir E, Bostanci S, Ekmekci P, Gurgey E
Dermatol Surg 2004 Jan;30(1):26-31. doi: 10.1111/j.1524-4725.2004.30004.x. PMID: 14692922

Recent clinical studies

Etiology

Optimal processing of ESD specimens to avoid pathological artifacts.
Reggiani Bonetti L, Manta R, Manno M, Conigliaro R, Missale G, Bassotti G, Villanacci V
Tech Coloproctol 2018 Nov;22(11):857-866. Epub 2018 Dec 17 doi: 10.1007/s10151-018-1887-x. PMID: 30560321
Tumors of the nail unit. A review. Part II: acquired localized longitudinal pachyonychia and masked nail tumors.
Perrin C
Am J Dermatopathol 2013 Oct;35(7):693-709; quiz 710-2. doi: 10.1097/DAD.0b013e318293f387. PMID: 24056180
Chemical matricectomy with 10% sodium hydroxide for the treatment of ingrowing toenails.
Ozdemir E, Bostanci S, Ekmekci P, Gurgey E
Dermatol Surg 2004 Jan;30(1):26-31. doi: 10.1111/j.1524-4725.2004.30004.x. PMID: 14692922
Reosteosynthesis of the tibial shaft. Part II. Changement of procedure after plate osteosynthesis.
Rommens PM, Van Raemdonck DE, Broos PL
Acta Chir Belg 1989 Sep-Oct;89(5):287-92. PMID: 2816212

Diagnosis

Identification of a novel LMX1B nonsense variant associated with congenital talipes equinovarus by prenatal exome sequencing: A case report.
Chen J, Xiang Q, Xiao X, Xu B, Xie H, Wang H, Yang M, Liu S
Mol Genet Genomic Med 2024 Jan;12(1):e2303. Epub 2023 Nov 6 doi: 10.1002/mgg3.2303. PMID: 37930140Free PMC Article
Zimmermann-Laband syndrome in monozygotic twins with a mild neurobehavioral phenotype lacking gingival overgrowth-A case report of a novel KCNN3 gene variant.
Schwarz M, Ryba L, Křepelová A, Moslerová V, Zelinová M, Turnovec M, Martinková J, Kratochvílová L, Drahanský M, Macek M Jr, Havlovicová M
Am J Med Genet A 2022 Apr;188(4):1083-1087. Epub 2021 Dec 14 doi: 10.1002/ajmg.a.62616. PMID: 34907639
Severe manifestations of hand-foot-genital syndrome associated with a novel HOXA13 mutation.
Imagawa E, Kayserili H, Nishimura G, Nakashima M, Tsurusaki Y, Saitsu H, Ikegawa S, Matsumoto N, Miyake N
Am J Med Genet A 2014 Sep;164A(9):2398-402. Epub 2014 Jun 16 doi: 10.1002/ajmg.a.36648. PMID: 24934387
Tumors of the nail unit. A review. Part II: acquired localized longitudinal pachyonychia and masked nail tumors.
Perrin C
Am J Dermatopathol 2013 Oct;35(7):693-709; quiz 710-2. doi: 10.1097/DAD.0b013e318293f387. PMID: 24056180
A second case of severe mental retardation and absent nails of hallux and pollex (Temple-Baraitser syndrome).
Gabbett MT, Clark RC, McGaughran JM
Am J Med Genet A 2008 Feb 15;146A(4):450-2. doi: 10.1002/ajmg.a.32129. PMID: 18203178

Therapy

Generalized linear porokeratosis.
Dervis E, Demirkesen C
Int J Dermatol 2006 Sep;45(9):1077-9. doi: 10.1111/j.1365-4632.2004.02490.x. PMID: 16961514
Chemical matricectomy with 10% sodium hydroxide for the treatment of ingrowing toenails.
Ozdemir E, Bostanci S, Ekmekci P, Gurgey E
Dermatol Surg 2004 Jan;30(1):26-31. doi: 10.1111/j.1524-4725.2004.30004.x. PMID: 14692922

Prognosis

Report of a fourth individual with a lethal syndrome of choanal atresia, athelia, evidence of renal tubulopathy, and family history of neck cysts.
Horvath GA, Armstrong L
Am J Med Genet A 2007 Jun 1;143A(11):1231-5. doi: 10.1002/ajmg.a.31734. PMID: 17486625
Reosteosynthesis of the tibial shaft. Part II. Changement of procedure after plate osteosynthesis.
Rommens PM, Van Raemdonck DE, Broos PL
Acta Chir Belg 1989 Sep-Oct;89(5):287-92. PMID: 2816212

Clinical prediction guides

Optimal processing of ESD specimens to avoid pathological artifacts.
Reggiani Bonetti L, Manta R, Manno M, Conigliaro R, Missale G, Bassotti G, Villanacci V
Tech Coloproctol 2018 Nov;22(11):857-866. Epub 2018 Dec 17 doi: 10.1007/s10151-018-1887-x. PMID: 30560321
Severe manifestations of hand-foot-genital syndrome associated with a novel HOXA13 mutation.
Imagawa E, Kayserili H, Nishimura G, Nakashima M, Tsurusaki Y, Saitsu H, Ikegawa S, Matsumoto N, Miyake N
Am J Med Genet A 2014 Sep;164A(9):2398-402. Epub 2014 Jun 16 doi: 10.1002/ajmg.a.36648. PMID: 24934387
Generalized linear porokeratosis.
Dervis E, Demirkesen C
Int J Dermatol 2006 Sep;45(9):1077-9. doi: 10.1111/j.1365-4632.2004.02490.x. PMID: 16961514
Congenital brachydactyly and nail hypoplasia: clue to bone-dependent nail formation.
Seitz CS, Hamm H
Br J Dermatol 2005 Jun;152(6):1339-42. doi: 10.1111/j.1365-2133.2005.06509.x. PMID: 15949005

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...