U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal CSF homovanillic acid concentration

MedGen UID:
1814353
Concept ID:
C5676788
Finding
HPO: HP:0034200

Definition

Any deviation from the normal concentration of homovanillic acid (HVA) in the cerebrospinal fluid. HVA is a metabolite of dopamine. [from HPO]

Professional guidelines

PubMed

Airaksinen E, Tuomisto L, Riikonen R
Brain Dev 1992 Nov;14(6):386-90. doi: 10.1016/s0387-7604(12)80345-7. PMID: 1283505

Recent clinical studies

Etiology

Fujita Y, Iwata S, Hidese S, Ishiwata S, Ide S, Tanaka H, Sonomoto K, Miyazaki Y, Nakayamada S, Ikenouchi A, Hattori K, Kunugi H, Yoshimura R, Tanaka Y
Rheumatology (Oxford) 2023 Oct 3;62(10):3490-3500. doi: 10.1093/rheumatology/kead091. PMID: 36852847
Vilanakis E, Papakonstantinou E, Paramera E, Argyri I, Drakou E, Kokkinou E, Zouvelou V, Outsika C, Pons R
Neuropediatrics 2023 Apr;54(2):126-133. Epub 2022 Nov 28 doi: 10.1055/a-1988-2412. PMID: 36442788
Assmann B, Köhler M, Hoffmann GF, Heales S, Surtees R
Pediatr Res 2002 Jul;52(1):91-4. doi: 10.1203/00006450-200207000-00017. PMID: 12084853
Kaye WH, Greeno CG, Moss H, Fernstrom J, Fernstrom M, Lilenfeld LR, Weltzin TE, Mann JJ
Arch Gen Psychiatry 1998 Oct;55(10):927-35. doi: 10.1001/archpsyc.55.10.927. PMID: 9783564
Pinkerton CR, Smith I, Leeming RJ, Sarna G, Hyland K, Curzon G, Chessells JM
J Pediatr 1986 Mar;108(3):470-4. doi: 10.1016/s0022-3476(86)80904-0. PMID: 2419534

Diagnosis

Fujita Y, Iwata S, Hidese S, Ishiwata S, Ide S, Tanaka H, Sonomoto K, Miyazaki Y, Nakayamada S, Ikenouchi A, Hattori K, Kunugi H, Yoshimura R, Tanaka Y
Rheumatology (Oxford) 2023 Oct 3;62(10):3490-3500. doi: 10.1093/rheumatology/kead091. PMID: 36852847
Vilanakis E, Papakonstantinou E, Paramera E, Argyri I, Drakou E, Kokkinou E, Zouvelou V, Outsika C, Pons R
Neuropediatrics 2023 Apr;54(2):126-133. Epub 2022 Nov 28 doi: 10.1055/a-1988-2412. PMID: 36442788
Garcia-Cazorla A, Duarte S, Serrano M, Nascimento A, Ormazabal A, Carrilho I, Briones P, Montoya J, Garesse R, Sala-Castellvi P, Pineda M, Artuch R
Mitochondrion 2008 Jun;8(3):273-8. Epub 2008 May 21 doi: 10.1016/j.mito.2008.05.001. PMID: 18558519
Verbeek MM, Willemsen MAAP, Wevers RA, Lagerwerf AJ, Abeling NGGM, Blau N, Thöny B, Vargiami E, Zafeiriou DI
Mol Genet Metab 2008 Aug;94(4):403-409. Epub 2008 May 27 doi: 10.1016/j.ymgme.2008.04.003. PMID: 18502672
Kaye WH, Greeno CG, Moss H, Fernstrom J, Fernstrom M, Lilenfeld LR, Weltzin TE, Mann JJ
Arch Gen Psychiatry 1998 Oct;55(10):927-35. doi: 10.1001/archpsyc.55.10.927. PMID: 9783564

Therapy

Garcia-Cazorla A, Duarte S, Serrano M, Nascimento A, Ormazabal A, Carrilho I, Briones P, Montoya J, Garesse R, Sala-Castellvi P, Pineda M, Artuch R
Mitochondrion 2008 Jun;8(3):273-8. Epub 2008 May 21 doi: 10.1016/j.mito.2008.05.001. PMID: 18558519
di Rocco A, Bottiglieri T, Dorfman D, Werner P, Morrison C, Simpson D
Clin Neuropharmacol 2000 Jul-Aug;23(4):190-4. doi: 10.1097/00002826-200007000-00004. PMID: 11020122
Baumgarten HG, Grozdanovic Z
Br J Psychiatry Suppl 1998;(35):13-20. PMID: 9829022
Pinkerton CR, Smith I, Leeming RJ, Sarna G, Hyland K, Curzon G, Chessells JM
J Pediatr 1986 Mar;108(3):470-4. doi: 10.1016/s0022-3476(86)80904-0. PMID: 2419534
Cunha L, Oliveira CR, Diniz M, Amaral R, Conçalves AF, Pio-Abreu J
J Neurol Neurosurg Psychiatry 1981 Mar;44(3):258-61. doi: 10.1136/jnnp.44.3.258. PMID: 6453208Free PMC Article

Prognosis

Garcia-Cazorla A, Duarte S, Serrano M, Nascimento A, Ormazabal A, Carrilho I, Briones P, Montoya J, Garesse R, Sala-Castellvi P, Pineda M, Artuch R
Mitochondrion 2008 Jun;8(3):273-8. Epub 2008 May 21 doi: 10.1016/j.mito.2008.05.001. PMID: 18558519
van der Cammen TJ, Tiemeier H, Engelhart MJ, Fekkes D
Int J Geriatr Psychiatry 2006 Sep;21(9):838-43. doi: 10.1002/gps.1569. PMID: 16955437
Sullivan GM, Oquendo MA, Huang YY, Mann JJ
Int J Neuropsychopharmacol 2006 Oct;9(5):547-56. Epub 2005 Nov 1 doi: 10.1017/S1461145705006231. PMID: 16259647
Assmann B, Köhler M, Hoffmann GF, Heales S, Surtees R
Pediatr Res 2002 Jul;52(1):91-4. doi: 10.1203/00006450-200207000-00017. PMID: 12084853
Kaye WH, Greeno CG, Moss H, Fernstrom J, Fernstrom M, Lilenfeld LR, Weltzin TE, Mann JJ
Arch Gen Psychiatry 1998 Oct;55(10):927-35. doi: 10.1001/archpsyc.55.10.927. PMID: 9783564

Clinical prediction guides

Saloner R, Cherner M, Grelotti DJ, Paolillo EW, Moore DJ, Heaton RK, Letendre SL, Kumar A, Grant I, Ellis RJ
Brain Behav Immun 2020 Nov;90:353-363. Epub 2020 Sep 20 doi: 10.1016/j.bbi.2020.09.012. PMID: 32966871Free PMC Article
Ogawa S, Hattori K, Sasayama D, Yokota Y, Matsumura R, Matsuo J, Ota M, Hori H, Teraishi T, Yoshida S, Noda T, Ohashi Y, Sato H, Higuchi T, Motohashi N, Kunugi H
Sci Rep 2015 Jan 15;5:7796. doi: 10.1038/srep07796. PMID: 25589364Free PMC Article
Garcia-Cazorla A, Duarte S, Serrano M, Nascimento A, Ormazabal A, Carrilho I, Briones P, Montoya J, Garesse R, Sala-Castellvi P, Pineda M, Artuch R
Mitochondrion 2008 Jun;8(3):273-8. Epub 2008 May 21 doi: 10.1016/j.mito.2008.05.001. PMID: 18558519
Assmann B, Köhler M, Hoffmann GF, Heales S, Surtees R
Pediatr Res 2002 Jul;52(1):91-4. doi: 10.1203/00006450-200207000-00017. PMID: 12084853
Higgins JJ, Harvey-White JD, Nee LE, Colli MJ, Grossi TA, Kopin IJ
J Neurol Neurosurg Psychiatry 1996 Dec;61(6):591-5. doi: 10.1136/jnnp.61.6.591. PMID: 8971105Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...