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Fetal intraventricular hemorrhage with ventriculomegaly

MedGen UID:
1814369
Concept ID:
C5676805
Pathologic Function
Synonyms: Grade III fetal intracranial hemorrhage; Grade III foetal intracranial haemorrhage
 
HPO: HP:0034218

Definition

A type of fetal intraventricular hemorrhage (IVH) characterized by spillover to ventricles with flooding of 50% or more of one or both lateral ventricles accrued accompanying ventriculomegaly, but with no apparent brain parenchymal injury. This type of IVH may be defined as a diameter exceeding 15 mm in the transverse diameter of the lateral ventricular atrium as visualiuzed by prenatal sonography. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFetal intraventricular hemorrhage with ventriculomegaly

Professional guidelines

PubMed

Kutuk MS, Yikilmaz A, Ozgun MT, Dolanbay M, Canpolat M, Uludag S, Uysal G, Tas M, Musa K
Childs Nerv Syst 2014 Mar;30(3):411-8. Epub 2013 Aug 2 doi: 10.1007/s00381-013-2243-0. PMID: 23907139
Whitelaw A, Aquilina K
Arch Dis Child Fetal Neonatal Ed 2012 May;97(3):F229-3. Epub 2011 Feb 2 doi: 10.1136/adc.2010.190173. PMID: 21289015
Durfee SM, Kim FM, Benson CB
J Ultrasound Med 2001 Mar;20(3):263-8. doi: 10.7863/jum.2001.20.3.263. PMID: 11270531

Recent clinical studies

Etiology

George E, Vassar R, Mogga A, Li Y, Norton ME, Gano D, Glenn OA
Pediatr Neurol 2023 Oct;147:63-67. Epub 2023 Jul 18 doi: 10.1016/j.pediatrneurol.2023.07.008. PMID: 37562171
Lai GY, Abdelmageed S, DeRegnier RO, Gaebler-Spira D, Dizon MLV, Lam SK
Pediatr Res 2022 Apr;91(5):1238-1247. Epub 2021 Jul 2 doi: 10.1038/s41390-021-01631-2. PMID: 34215837
Dall'Asta A, van Oostrum NHM, Basheer SN, Paramasivam G, Ghi T, Galli L, Groenenberg IA, Tangi A, Accorsi P, Echevarria M, Angeles Rodríguez Perez M, Albaiges Baiget G, Prefumo F, Frusca T, Go AT, Lees CC
Ultraschall Med 2018 Dec;39(6):675-689. Epub 2018 Jul 5 doi: 10.1055/a-0627-7173. PMID: 29975968
Letouzey M, Chadie A, Brasseur-Daudruy M, Proust F, Verspyck E, Boileau P, Marret S
Prenat Diagn 2017 Aug;37(8):820-826. Epub 2017 Jul 19 doi: 10.1002/pd.5095. PMID: 28622418
Martillotti G, Rypens F, David M, Catalfamo N, Dubé J, Taillefer C, Lachance C, Audibert F
Fetal Diagn Ther 2017;42(1):35-41. Epub 2016 Sep 7 doi: 10.1159/000448994. PMID: 27597992

Diagnosis

Wang M, Yin Z, Miao J, Wu Y
Arch Gynecol Obstet 2022 Jan;305(1):49-54. Epub 2021 Jun 11 doi: 10.1007/s00404-021-06113-8. PMID: 34115181
Letouzey M, Chadie A, Brasseur-Daudruy M, Proust F, Verspyck E, Boileau P, Marret S
Prenat Diagn 2017 Aug;37(8):820-826. Epub 2017 Jul 19 doi: 10.1002/pd.5095. PMID: 28622418
Bandaralage SP, Farnaghi S, Dulhunty JM, Kothari A
Pediatr Radiol 2016 Mar;46(3):357-64. Epub 2016 Jan 11 doi: 10.1007/s00247-015-3492-8. PMID: 26754537
Kutuk MS, Yikilmaz A, Ozgun MT, Dolanbay M, Canpolat M, Uludag S, Uysal G, Tas M, Musa K
Childs Nerv Syst 2014 Mar;30(3):411-8. Epub 2013 Aug 2 doi: 10.1007/s00381-013-2243-0. PMID: 23907139
Whitelaw A, Aquilina K
Arch Dis Child Fetal Neonatal Ed 2012 May;97(3):F229-3. Epub 2011 Feb 2 doi: 10.1136/adc.2010.190173. PMID: 21289015

Therapy

Wang M, Yin Z, Miao J, Wu Y
Arch Gynecol Obstet 2022 Jan;305(1):49-54. Epub 2021 Jun 11 doi: 10.1007/s00404-021-06113-8. PMID: 34115181
Romantsik O, Agyemang AA, Sveinsdóttir S, Rutardóttir S, Holmqvist B, Cinthio M, Mörgelin M, Gumus G, Karlsson H, Hansson SR, Åkerström B, Ley D, Gram M
J Neuroinflammation 2019 Jun 7;16(1):122. doi: 10.1186/s12974-019-1486-4. PMID: 31174551Free PMC Article
Martillotti G, Rypens F, David M, Catalfamo N, Dubé J, Taillefer C, Lachance C, Audibert F
Fetal Diagn Ther 2017;42(1):35-41. Epub 2016 Sep 7 doi: 10.1159/000448994. PMID: 27597992
Gherman RB, Chauhan SP
J Reprod Med 2014 Sep-Oct;59(9-10):501-3. PMID: 25330694
Whitelaw A, Aquilina K
Arch Dis Child Fetal Neonatal Ed 2012 May;97(3):F229-3. Epub 2011 Feb 2 doi: 10.1136/adc.2010.190173. PMID: 21289015

Prognosis

Whitehead MT, Limperopoulos C, Schlatterer SD, Mulkey SB, Fraser JL, du Plessis AJ
Pediatr Radiol 2023 Aug;53(9):1941-1950. Epub 2023 May 15 doi: 10.1007/s00247-023-05687-6. PMID: 37183230
Maki Y, Ishibashi R, Yasuda T, Tokumasu H, Yamamoto Y, Goda A, Yamashita H, Morita T, Ikeda H, Chin M, Yamagata S
World Neurosurg 2022 Jul;163:e532-e538. Epub 2022 Apr 9 doi: 10.1016/j.wneu.2022.04.023. PMID: 35405320
Lai GY, Abdelmageed S, DeRegnier RO, Gaebler-Spira D, Dizon MLV, Lam SK
Pediatr Res 2022 Apr;91(5):1238-1247. Epub 2021 Jul 2 doi: 10.1038/s41390-021-01631-2. PMID: 34215837
Dall'Asta A, van Oostrum NHM, Basheer SN, Paramasivam G, Ghi T, Galli L, Groenenberg IA, Tangi A, Accorsi P, Echevarria M, Angeles Rodríguez Perez M, Albaiges Baiget G, Prefumo F, Frusca T, Go AT, Lees CC
Ultraschall Med 2018 Dec;39(6):675-689. Epub 2018 Jul 5 doi: 10.1055/a-0627-7173. PMID: 29975968
Martillotti G, Rypens F, David M, Catalfamo N, Dubé J, Taillefer C, Lachance C, Audibert F
Fetal Diagn Ther 2017;42(1):35-41. Epub 2016 Sep 7 doi: 10.1159/000448994. PMID: 27597992

Clinical prediction guides

Whitehead MT, Limperopoulos C, Schlatterer SD, Mulkey SB, Fraser JL, du Plessis AJ
Pediatr Radiol 2023 Aug;53(9):1941-1950. Epub 2023 May 15 doi: 10.1007/s00247-023-05687-6. PMID: 37183230
Maki Y, Ishibashi R, Yasuda T, Tokumasu H, Yamamoto Y, Goda A, Yamashita H, Morita T, Ikeda H, Chin M, Yamagata S
World Neurosurg 2022 Jul;163:e532-e538. Epub 2022 Apr 9 doi: 10.1016/j.wneu.2022.04.023. PMID: 35405320
Lai GY, Aouad P, DeRegnier RO, Dizon MLV, Palasis S, Lam SK
Pediatr Res 2022 Dec;92(6):1621-1629. Epub 2022 Feb 19 doi: 10.1038/s41390-022-01993-1. PMID: 35184137
Lai GY, Abdelmageed S, DeRegnier RO, Gaebler-Spira D, Dizon MLV, Lam SK
Pediatr Res 2022 Apr;91(5):1238-1247. Epub 2021 Jul 2 doi: 10.1038/s41390-021-01631-2. PMID: 34215837
Andrikopoulou M, Almalki A, Farzin A, Cordeiro CN, Johnston MV, Burd I
Int J Dev Neurosci 2014 Aug;36:25-31. Epub 2014 Apr 24 doi: 10.1016/j.ijdevneu.2014.04.002. PMID: 24768951Free PMC Article

Recent systematic reviews

Di Mascio D, Sileo FG, Khalil A, Rizzo G, Persico N, Brunelli R, Giancotti A, Panici PB, Acharya G, D'Antonio F
Ultrasound Obstet Gynecol 2019 Aug;54(2):164-171. Epub 2019 Jul 11 doi: 10.1002/uog.20197. PMID: 30549340
Bandaralage SP, Farnaghi S, Dulhunty JM, Kothari A
Pediatr Radiol 2016 Mar;46(3):357-64. Epub 2016 Jan 11 doi: 10.1007/s00247-015-3492-8. PMID: 26754537

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