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Malignant tumor of rectum

MedGen UID:
181763
Concept ID:
C0949022
Neoplastic Process
Synonym: Rectal cancer
SNOMED CT: Malignant tumor of rectum (363351006)
 
Monarch Initiative: MONDO:0006519

Definition

A primary or metastatic malignant neoplasm that affects the rectum. Representative examples include carcinoma, lymphoma, and sarcoma. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Vogel JD, Felder SI, Bhama AR, Hawkins AT, Langenfeld SJ, Shaffer VO, Thorsen AJ, Weiser MR, Chang GJ, Lightner AL, Feingold DL, Paquette IM
Dis Colon Rectum 2022 Feb 1;65(2):148-177. doi: 10.1097/DCR.0000000000002323. PMID: 34775402
Wu Z, Li Y, Zhang Y, Hu H, Wu T, Liu S, Chen W, Xie S, Lu Z
Technol Cancer Res Treat 2020 Jan-Dec;19:1533033820980426. doi: 10.1177/1533033820980426. PMID: 33353503Free PMC Article
Horvat N, Carlos Tavares Rocha C, Clemente Oliveira B, Petkovska I, Gollub MJ
Radiographics 2019 Mar-Apr;39(2):367-387. Epub 2019 Feb 15 doi: 10.1148/rg.2019180114. PMID: 30768361Free PMC Article

Curated

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Rectal Cancer, 2024

Recent clinical studies

Etiology

Khan SI, O'Sullivan NJ, Temperley HC, Rausa E, Mehigan BJ, McCormick P, Larkin JO, Kavanagh DO, Kelly ME
Curr Oncol 2022 Dec 28;30(1):416-429. doi: 10.3390/curroncol30010034. PMID: 36661683Free PMC Article
Fernandes MC, Gollub MJ, Brown G
Surg Oncol 2022 Aug;43:101739. Epub 2022 Mar 18 doi: 10.1016/j.suronc.2022.101739. PMID: 35339339Free PMC Article
Pechlivanides G, Gourtsoyianni S, Gouvas N, Sougklakos J, Xynos E
Updates Surg 2021 Apr;73(2):513-526. Epub 2020 Oct 27 doi: 10.1007/s13304-020-00903-6. PMID: 33108641
Tilg H, Adolph TE, Gerner RR, Moschen AR
Cancer Cell 2018 Jun 11;33(6):954-964. Epub 2018 Apr 12 doi: 10.1016/j.ccell.2018.03.004. PMID: 29657127
Todorov G, Maslyankov S
Khirurgiia (Sofiia) 2015;81(2):13-28. PMID: 26668986

Diagnosis

Monreal-Robles R, Jáquez-Quintana JO, Benavides-Salgado DE, González-González JA
Rev Gastroenterol Mex (Engl Ed) 2021 Jul-Sep;86(3):276-286. Epub 2021 Jun 9 doi: 10.1016/j.rgmxen.2021.06.001. PMID: 34116964
Sano W, Hirata D, Teramoto A, Iwatate M, Hattori S, Fujita M, Sano Y
World J Gastroenterol 2020 May 21;26(19):2276-2285. doi: 10.3748/wjg.v26.i19.2276. PMID: 32476792Free PMC Article
Liang F, Li J, Yu K, Zhang K, Liu T, Li J
Med Sci Monit 2020 Jan 11;26:e919803. doi: 10.12659/MSM.919803. PMID: 31926113Free PMC Article
Horvat N, Carlos Tavares Rocha C, Clemente Oliveira B, Petkovska I, Gollub MJ
Radiographics 2019 Mar-Apr;39(2):367-387. Epub 2019 Feb 15 doi: 10.1148/rg.2019180114. PMID: 30768361Free PMC Article
Bullard Dunn K
Surg Clin North Am 2010 Feb;90(1):163-71, Table of Contents. doi: 10.1016/j.suc.2009.09.009. PMID: 20109640

Therapy

Bahadoer RR, Hospers GAP, Marijnen CAM, Peeters KCMJ, Putter H, Dijkstra EA, Kranenbarg EM, Roodvoets AGH, van Etten B, Nilsson PJ, Glimelius B, van de Velde CJH; collaborative investigators
Eur J Cancer 2023 May;185:139-149. Epub 2023 Mar 7 doi: 10.1016/j.ejca.2023.02.027. PMID: 36996624
Liu G, Zhang S, Zhang Y, Fu X, Liu X
Curr Treat Options Oncol 2022 Jul;23(7):961-979. Epub 2022 Apr 18 doi: 10.1007/s11864-022-00984-y. PMID: 35438444Free PMC Article
Connelly TM, Clancy C, Hu S, Steele SR, Kessler H
BMJ Case Rep 2022 Mar 14;15(3) doi: 10.1136/bcr-2021-248505. PMID: 35288433Free PMC Article
Feeney G, Sehgal R, Sheehan M, Hogan A, Regan M, Joyce M, Kerin M
World J Gastroenterol 2019 Sep 7;25(33):4850-4869. doi: 10.3748/wjg.v25.i33.4850. PMID: 31543678Free PMC Article
Ciseł B, Pietrzak L, Michalski W, Wyrwicz L, Rutkowski A, Kosakowska E, Cencelewicz A, Spałek M, Polkowski W, Jankiewicz M, Styliński R, Bębenek M, Kapturkiewicz B, Maciejczyk A, Sadowski J, Zygulska J, Zegarski W, Jankowski M, Las-Jankowska M, Toczko Z, Żelazowska-Omiotek U, Kępka L, Socha J, Wasilewska-Tesluk E, Markiewicz W, Kładny J, Majewski A, Kapuściński W, Suwiński R, Bujko K; Polish Colorectal Study Group
Ann Oncol 2019 Aug 1;30(8):1298-1303. doi: 10.1093/annonc/mdz186. PMID: 31192355

Prognosis

Fernandes MC, Gollub MJ, Brown G
Surg Oncol 2022 Aug;43:101739. Epub 2022 Mar 18 doi: 10.1016/j.suronc.2022.101739. PMID: 35339339Free PMC Article
Arya S, Sen S, Engineer R, Saklani A, Pandey T
Semin Ultrasound CT MR 2020 Apr;41(2):183-206. Epub 2020 Jan 24 doi: 10.1053/j.sult.2020.01.001. PMID: 32446431
Ciseł B, Pietrzak L, Michalski W, Wyrwicz L, Rutkowski A, Kosakowska E, Cencelewicz A, Spałek M, Polkowski W, Jankiewicz M, Styliński R, Bębenek M, Kapturkiewicz B, Maciejczyk A, Sadowski J, Zygulska J, Zegarski W, Jankowski M, Las-Jankowska M, Toczko Z, Żelazowska-Omiotek U, Kępka L, Socha J, Wasilewska-Tesluk E, Markiewicz W, Kładny J, Majewski A, Kapuściński W, Suwiński R, Bujko K; Polish Colorectal Study Group
Ann Oncol 2019 Aug 1;30(8):1298-1303. doi: 10.1093/annonc/mdz186. PMID: 31192355
Goldenberg BA, Holliday EB, Helewa RM, Singh H
Am J Gastroenterol 2018 Dec;113(12):1763-1771. doi: 10.1038/s41395-018-0180-y. PMID: 30008472Free PMC Article
Hoeffel C, Mulé S, Laurent V, Bouché O, Volet J, Soyer P
Diagn Interv Imaging 2014 May;95(5):485-94. Epub 2014 Apr 2 doi: 10.1016/j.diii.2014.03.005. PMID: 24703376

Clinical prediction guides

Khan SI, O'Sullivan NJ, Temperley HC, Rausa E, Mehigan BJ, McCormick P, Larkin JO, Kavanagh DO, Kelly ME
Curr Oncol 2022 Dec 28;30(1):416-429. doi: 10.3390/curroncol30010034. PMID: 36661683Free PMC Article
Fernandes MC, Gollub MJ, Brown G
Surg Oncol 2022 Aug;43:101739. Epub 2022 Mar 18 doi: 10.1016/j.suronc.2022.101739. PMID: 35339339Free PMC Article
Salembier C, Villeirs G, De Bari B, Hoskin P, Pieters BR, Van Vulpen M, Khoo V, Henry A, Bossi A, De Meerleer G, Fonteyne V
Radiother Oncol 2018 Apr;127(1):49-61. doi: 10.1016/j.radonc.2018.01.014. PMID: 29496279
De Maio G, Zama E, Rengucci C, Calistri D
Oncotarget 2017 Feb 14;8(7):12406-12416. doi: 10.18632/oncotarget.13628. PMID: 27902488Free PMC Article
Todorov G, Maslyankov S
Khirurgiia (Sofiia) 2015;81(2):13-28. PMID: 26668986

Recent systematic reviews

Garcia L, Pearce M, Abbas A, Mok A, Strain T, Ali S, Crippa A, Dempsey PC, Golubic R, Kelly P, Laird Y, McNamara E, Moore S, de Sa TH, Smith AD, Wijndaele K, Woodcock J, Brage S
Br J Sports Med 2023 Aug;57(15):979-989. Epub 2023 Feb 28 doi: 10.1136/bjsports-2022-105669. PMID: 36854652Free PMC Article
Nardone V, Reginelli A, Grassi R, Boldrini L, Vacca G, D'Ippolito E, Annunziata S, Farchione A, Belfiore MP, Desideri I, Cappabianca S
Radiol Med 2021 Dec;126(12):1571-1583. Epub 2021 Dec 4 doi: 10.1007/s11547-021-01436-7. PMID: 34865190
Liu S, Jiang T, Xiao L, Yang S, Liu Q, Gao Y, Chen G, Xiao W
Oncologist 2021 Sep;26(9):e1555-e1566. Epub 2021 Jun 7 doi: 10.1002/onco.13824. PMID: 33987952Free PMC Article
Hanna TP, King WD, Thibodeau S, Jalink M, Paulin GA, Harvey-Jones E, O'Sullivan DE, Booth CM, Sullivan R, Aggarwal A
BMJ 2020 Nov 4;371:m4087. doi: 10.1136/bmj.m4087. PMID: 33148535Free PMC Article
Bailie L, Loughrey MB, Coleman HG
Gastroenterology 2017 Jan;152(1):92-104. Epub 2016 Sep 14 doi: 10.1053/j.gastro.2016.09.003. PMID: 27639804

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NCCN, 2024
      NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Rectal Cancer, 2024

    Consumer resources

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