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Disorder of joint of spine

MedGen UID:
181888
•Concept ID:
C0949691
•
Disease or Syndrome
Synonyms: Bechterew Syndrome; Marie Strumpell Spondylitis; Marie-Strumpell Spondylitis; Spondylarthropathies; Spondylarthropathy; Spondylitis, Marie-Strumpell; Spondyloarthropathies; Spondyloarthropathy; Syndrome, Bechterew
SNOMED CT: Disorder of joint of spine (372109003); Spondyloarthropathy (372109003); Spondylarthrosis (8847002); Spondarthropathy (8847002)

Definition

Heterogeneous group of arthritic diseases sharing clinical and radiologic features. They are associated with the HLA-B27 ANTIGEN and some with a triggering infection. Most involve the axial joints in the SPINE, particularly the SACROILIAC JOINT, but can also involve asymmetric peripheral joints. Subsets include ANKYLOSING SPONDYLITIS; REACTIVE ARTHRITIS; PSORIATIC ARTHRITIS; and others. [from MeSH]

Professional guidelines

PubMed

Axial spondyloarthritis: new advances in diagnosis and management.
Ritchlin C, Adamopoulos IE
BMJ 2021 Jan 4;372:m4447. doi: 10.1136/bmj.m4447. PMID: 33397652
Recent advances in ankylosing spondylitis: understanding the disease and management.
Garcia-Montoya L, Gul H, Emery P
F1000Res 2018;7 Epub 2018 Sep 21 doi: 10.12688/f1000research.14956.1. PMID: 30345001Free PMC Article
Exercise for ankylosing spondylitis: An evidence-based consensus statement.
Millner JR, Barron JS, Beinke KM, Butterworth RH, Chasle BE, Dutton LJ, Lewington MA, Lim EG, Morley TB, O'Reilly JE, Pickering KA, Winzenberg T, Zochling J
Semin Arthritis Rheum 2016 Feb;45(4):411-27. Epub 2015 Aug 18 doi: 10.1016/j.semarthrit.2015.08.003. PMID: 26493464

Recent clinical studies

Etiology

Points to consider for the treatment of immune-mediated inflammatory diseases with Janus kinase inhibitors: a consensus statement.
Nash P, Kerschbaumer A, Dörner T, Dougados M, Fleischmann RM, Geissler K, McInnes I, Pope JE, van der Heijde D, Stoffer-Marx M, Takeuchi T, Trauner M, Winthrop KL, de Wit M, Aletaha D, Baraliakos X, Boehncke WH, Emery P, Isaacs JD, Kremer J, Lee EB, Maksymowych WP, Voshaar M, Tam LS, Tanaka Y, van den Bosch F, Westhovens R, Xavier R, Smolen JS
Ann Rheum Dis 2021 Jan;80(1):71-87. Epub 2020 Nov 6 doi: 10.1136/annrheumdis-2020-218398. PMID: 33158881Free PMC Article
Axial psoriatic arthritis: An update for dermatologists.
Gottlieb AB, Merola JF
J Am Acad Dermatol 2021 Jan;84(1):92-101. Epub 2020 Jul 31 doi: 10.1016/j.jaad.2020.05.089. PMID: 32747079
Preventing psoriatic arthritis: focusing on patients with psoriasis at increased risk of transition.
Scher JU, Ogdie A, Merola JF, Ritchlin C
Nat Rev Rheumatol 2019 Mar;15(3):153-166. doi: 10.1038/s41584-019-0175-0. PMID: 30742092
The microbiome and HLA-B27-associated acute anterior uveitis.
Rosenbaum JT, Asquith M
Nat Rev Rheumatol 2018 Dec;14(12):704-713. doi: 10.1038/s41584-018-0097-2. PMID: 30301938Free PMC Article
The Seronegative Spondyloarthropathies.
Duba AS, Mathew SD
Prim Care 2018 Jun;45(2):271-287. doi: 10.1016/j.pop.2018.02.005. PMID: 29759124

Diagnosis

Axial spondyloarthritis.
Navarro-Compán V, Sepriano A, El-Zorkany B, van der Heijde D
Ann Rheum Dis 2021 Dec;80(12):1511-1521. Epub 2021 Oct 6 doi: 10.1136/annrheumdis-2021-221035. PMID: 34615639
Axial psoriatic arthritis: An update for dermatologists.
Gottlieb AB, Merola JF
J Am Acad Dermatol 2021 Jan;84(1):92-101. Epub 2020 Jul 31 doi: 10.1016/j.jaad.2020.05.089. PMID: 32747079
The pathogenesis of psoriatic arthritis.
Veale DJ, Fearon U
Lancet 2018 Jun 2;391(10136):2273-2284. Epub 2018 Jun 1 doi: 10.1016/S0140-6736(18)30830-4. PMID: 29893226
Psoriatic arthritis: state of the art review.
Coates LC, Helliwell PS
Clin Med (Lond) 2017 Feb;17(1):65-70. doi: 10.7861/clinmedicine.17-1-65. PMID: 28148584Free PMC Article
Ankylosing spondylitis: diagnosis and management.
Bond D
Nurs Stand 2013 Dec 18;28(16-18):52-9; quiz 60. doi: 10.7748/ns2013.12.28.16.52.e7807. PMID: 24345154

Therapy

Axial psoriatic arthritis: An update for dermatologists.
Gottlieb AB, Merola JF
J Am Acad Dermatol 2021 Jan;84(1):92-101. Epub 2020 Jul 31 doi: 10.1016/j.jaad.2020.05.089. PMID: 32747079
2019 Update of the American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis.
Ward MM, Deodhar A, Gensler LS, Dubreuil M, Yu D, Khan MA, Haroon N, Borenstein D, Wang R, Biehl A, Fang MA, Louie G, Majithia V, Ng B, Bigham R, Pianin M, Shah AA, Sullivan N, Turgunbaev M, Oristaglio J, Turner A, Maksymowych WP, Caplan L
Arthritis Care Res (Hoboken) 2019 Oct;71(10):1285-1299. Epub 2019 Aug 21 doi: 10.1002/acr.24025. PMID: 31436026Free PMC Article
Inflammatory bowel diseases and spondyloarthropathies: From pathogenesis to treatment.
Fragoulis GE, Liava C, Daoussis D, Akriviadis E, Garyfallos A, Dimitroulas T
World J Gastroenterol 2019 May 14;25(18):2162-2176. doi: 10.3748/wjg.v25.i18.2162. PMID: 31143068Free PMC Article
Effectiveness of Exercise Programs in Ankylosing Spondylitis: A Meta-Analysis of Randomized Controlled Trials.
Pécourneau V, Degboé Y, Barnetche T, Cantagrel A, Constantin A, Ruyssen-Witrand A
Arch Phys Med Rehabil 2018 Feb;99(2):383-389.e1. Epub 2017 Aug 30 doi: 10.1016/j.apmr.2017.07.015. PMID: 28860095
Physiotherapy interventions for ankylosing spondylitis.
Dagfinrud H, Kvien TK, Hagen KB
Cochrane Database Syst Rev 2008 Jan 23;2008(1):CD002822. doi: 10.1002/14651858.CD002822.pub3. PMID: 18254008Free PMC Article

Prognosis

Changes in ankylosing spondylitis incidence, prevalence and time to diagnosis over two decades.
Crossfield SSR, Marzo-Ortega H, Kingsbury SR, Pujades-Rodriguez M, Conaghan PG
RMD Open 2021 Dec;7(3) doi: 10.1136/rmdopen-2021-001888. PMID: 34887345Free PMC Article
Swiss ball exercises improve muscle strength and walking performance in ankylosing spondylitis: a randomized controlled trial.
Souza MC, Jennings F, Morimoto H, Natour J
Rev Bras Reumatol Engl Ed 2017 Jan-Feb;57(1):45-55. Epub 2016 Oct 20 doi: 10.1016/j.rbre.2016.09.009. PMID: 28137402
Reactive arthritis.
Hannu T
Best Pract Res Clin Rheumatol 2011 Jun;25(3):347-57. doi: 10.1016/j.berh.2011.01.018. PMID: 22100285
Uveitis.
Muñoz-Fernández S, Martín-Mola E
Best Pract Res Clin Rheumatol 2006 Jun;20(3):487-505. doi: 10.1016/j.berh.2006.03.008. PMID: 16777578
Seronegative spondyloarthritides.
Olivieri I, van Tubergen A, Salvarani C, van der Linden S
Best Pract Res Clin Rheumatol 2002 Dec;16(5):723-39. doi: 10.1053/berh.2002.0263. PMID: 12473270

Clinical prediction guides

Inflammatory bowel diseases and spondyloarthropathies: From pathogenesis to treatment.
Fragoulis GE, Liava C, Daoussis D, Akriviadis E, Garyfallos A, Dimitroulas T
World J Gastroenterol 2019 May 14;25(18):2162-2176. doi: 10.3748/wjg.v25.i18.2162. PMID: 31143068Free PMC Article
Modified stoke ankylosing spondylitis spinal score as an outcome measure to assess the impact of treatment on structural progression in ankylosing spondylitis.
van der Heijde D, Braun J, Deodhar A, Baraliakos X, Landewé R, Richards HB, Porter B, Readie A
Rheumatology (Oxford) 2019 Mar 1;58(3):388-400. doi: 10.1093/rheumatology/key128. PMID: 29860356Free PMC Article
Imaging of axial spondyloarthritis. New aspects and differential diagnoses.
Braun J, Baraliakos X, Buehring B, Kiltz U, Fruth M
Clin Exp Rheumatol 2018 Sep-Oct;36 Suppl 114(5):35-42. Epub 2018 Oct 1 PMID: 30296971
Reliability of a consensus-based ultrasound definition and scoring for enthesitis in spondyloarthritis and psoriatic arthritis: an OMERACT US initiative.
Balint PV, Terslev L, Aegerter P, Bruyn GAW, Chary-Valckenaere I, Gandjbakhch F, Iagnocco A, Jousse-Joulin S, Möller I, Naredo E, Schmidt WA, Wakefield RJ, D'Agostino MA; OMERACT Ultrasound Task Force members
Ann Rheum Dis 2018 Dec;77(12):1730-1735. Epub 2018 Aug 3 doi: 10.1136/annrheumdis-2018-213609. PMID: 30076154
Measures of symptoms and disease status in ankylosing spondylitis: Ankylosing Spondylitis Disease Activity Score (ASDAS), Ankylosing Spondylitis Quality of Life Scale (ASQoL), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Global Score (BAS-G), Bath Ankylosing Spondylitis Metrology Index (BASMI), Dougados Functional Index (DFI), and Health Assessment Questionnaire for the Spondylarthropathies (HAQ-S).
Zochling J
Arthritis Care Res (Hoboken) 2011 Nov;63 Suppl 11:S47-58. doi: 10.1002/acr.20575. PMID: 22588768

Recent systematic reviews

Efficacy and safety of biological DMARDs: a systematic literature review informing the 2022 update of the ASAS-EULAR recommendations for the management of axial spondyloarthritis.
Webers C, Ortolan A, Sepriano A, Falzon L, Baraliakos X, Landewé RBM, Ramiro S, van der Heijde D, Nikiphorou E
Ann Rheum Dis 2023 Jan;82(1):130-141. Epub 2022 Oct 21 doi: 10.1136/ard-2022-223298. PMID: 36270657
Efficacy and Safety of Curcumin and Curcuma longa Extract in the Treatment of Arthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trial.
Zeng L, Yang T, Yang K, Yu G, Li J, Xiang W, Chen H
Front Immunol 2022;13:891822. Epub 2022 Jul 22 doi: 10.3389/fimmu.2022.891822. PMID: 35935936Free PMC Article
JAK inhibitors and psoriatic arthritis: A systematic review and meta-analysis.
Campanaro F, Batticciotto A, Zaffaroni A, Cappelli A, Donadini MP, Squizzato A
Autoimmun Rev 2021 Oct;20(10):102902. Epub 2021 Jul 15 doi: 10.1016/j.autrev.2021.102902. PMID: 34274542
Ankylosing spondylitis risk factors: a systematic literature review.
Hwang MC, Ridley L, Reveille JD
Clin Rheumatol 2021 Aug;40(8):3079-3093. Epub 2021 Mar 22 doi: 10.1007/s10067-021-05679-7. PMID: 33754220Free PMC Article
Exercise for ankylosing spondylitis: An evidence-based consensus statement.
Millner JR, Barron JS, Beinke KM, Butterworth RH, Chasle BE, Dutton LJ, Lewington MA, Lim EG, Morley TB, O'Reilly JE, Pickering KA, Winzenberg T, Zochling J
Semin Arthritis Rheum 2016 Feb;45(4):411-27. Epub 2015 Aug 18 doi: 10.1016/j.semarthrit.2015.08.003. PMID: 26493464

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