U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Osteochondrosis

MedGen UID:
18216
Concept ID:
C0029429
Disease or Syndrome
Synonym: Osteochondroses
SNOMED CT: Osteochondrosis (19579005)
 
HPO: HP:0040188
Monarch Initiative: MONDO:0018381
Orphanet: ORPHA399319

Definition

Abnormal growth ossification centers in children. Initially a degeneration/ necrosis followed by regeneration or recalcification. [from HPO]

Conditions with this feature

Juvenile osteochondrosis of spine
MedGen UID:
19885
Concept ID:
C0036310
Disease or Syndrome
Scheuermann disease is characterized by lumbar or thoracic kyphosis or both, back pain, and a variety of vertebral changes including wedging, endplate irregularity, narrowing of disc spaces, Schmorl nodes, and detached epiphyseal rings. It is reported to occur more frequently in boys than in girls (summary by McKenzie and Sillence, 1992).

Professional guidelines

PubMed

Schmitt R, Kalb KH, Christopoulos G, Grunz JP
Semin Musculoskelet Radiol 2019 Oct;23(5):523-533. Epub 2019 Sep 25 doi: 10.1055/s-0039-1695719. PMID: 31556087
Seybold JD, Zide JR
Foot Ankle Clin 2018 Mar;23(1):157-169. doi: 10.1016/j.fcl.2017.09.011. PMID: 29362030
Nelitz M, Lippacher S, Krauspe R, Reichel H
Dtsch Arztebl Int 2009 Jul;106(31-32):517-23. Epub 2009 Aug 3 doi: 10.3238/arztebl.2009.0517. PMID: 19730720Free PMC Article

Recent clinical studies

Etiology

Bezuglov EN, Tikhonova АА, Chubarovskiy PV, Repetyuk АD, Khaitin VY, Lazarev AM, Usmanova EM
Int Orthop 2020 Sep;44(9):1737-1743. Epub 2020 Apr 28 doi: 10.1007/s00264-020-04572-3. PMID: 32346752
Ladenhauf HN, Seitlinger G, Green DW
Curr Opin Pediatr 2020 Feb;32(1):107-112. doi: 10.1097/MOP.0000000000000842. PMID: 31714260
Achar S, Yamanaka J
Am Fam Physician 2019 May 15;99(10):610-618. PMID: 31083875
Janoyer M
Orthop Traumatol Surg Res 2019 Feb;105(1S):S111-S121. Epub 2018 Feb 23 doi: 10.1016/j.otsr.2018.01.009. PMID: 29481866
Danger F, Wasyliw C, Varich L
Semin Musculoskelet Radiol 2018 Feb;22(1):118-124. Epub 2018 Feb 6 doi: 10.1055/s-0038-1627094. PMID: 29409078

Diagnosis

Achar S, Yamanaka J
Am Fam Physician 2019 May 15;99(10):610-618. PMID: 31083875
Janoyer M
Orthop Traumatol Surg Res 2019 Feb;105(1S):S111-S121. Epub 2018 Feb 23 doi: 10.1016/j.otsr.2018.01.009. PMID: 29481866
Circi E, Atalay Y, Beyzadeoglu T
Musculoskelet Surg 2017 Dec;101(3):195-200. Epub 2017 Jun 7 doi: 10.1007/s12306-017-0479-7. PMID: 28593576
Márquez Sánchez P
Radiologia 2016 Apr;58 Suppl 1:50-9. Epub 2016 Feb 9 doi: 10.1016/j.rx.2015.12.005. PMID: 26869521
Launay F
Orthop Traumatol Surg Res 2015 Feb;101(1 Suppl):S139-47. Epub 2014 Dec 30 doi: 10.1016/j.otsr.2014.06.030. PMID: 25555804

Therapy

Polshchakova T, Gushcha S, Bevz L, Plakida A
Eur Rev Med Pharmacol Sci 2022 Sep;26(17):6107-6109. doi: 10.26355/eurrev_202209_29627. PMID: 36111911
Qiao L, Liu X, He Y, Zhang J, Huang H, Bian W, Chilufya MM, Zhao Y, Han J
Int J Mol Sci 2021 Nov 3;22(21) doi: 10.3390/ijms222111932. PMID: 34769367Free PMC Article
Neuhaus C, Appenzeller-Herzog C, Faude O
Phys Ther Sport 2021 May;49:178-187. Epub 2021 Mar 9 doi: 10.1016/j.ptsp.2021.03.002. PMID: 33744766
Weiss JE, Stinson JN
Pediatr Clin North Am 2018 Aug;65(4):801-826. doi: 10.1016/j.pcl.2018.04.004. PMID: 30031499
Seybold JD, Zide JR
Foot Ankle Clin 2018 Mar;23(1):157-169. doi: 10.1016/j.fcl.2017.09.011. PMID: 29362030

Prognosis

Janoyer M
Orthop Traumatol Surg Res 2019 Feb;105(1S):S111-S121. Epub 2018 Feb 23 doi: 10.1016/j.otsr.2018.01.009. PMID: 29481866
Danger F, Wasyliw C, Varich L
Semin Musculoskelet Radiol 2018 Feb;22(1):118-124. Epub 2018 Feb 6 doi: 10.1055/s-0038-1627094. PMID: 29409078
Circi E, Atalay Y, Beyzadeoglu T
Musculoskelet Surg 2017 Dec;101(3):195-200. Epub 2017 Jun 7 doi: 10.1007/s12306-017-0479-7. PMID: 28593576
Márquez Sánchez P
Radiologia 2016 Apr;58 Suppl 1:50-9. Epub 2016 Feb 9 doi: 10.1016/j.rx.2015.12.005. PMID: 26869521
Sanders RK, Crim JR
Semin Ultrasound CT MR 2001 Aug;22(4):352-70. doi: 10.1016/s0887-2171(01)90026-5. PMID: 11513159

Clinical prediction guides

Saxena A, Fournier M, Patel P, Maffulli N
J Foot Ankle Surg 2022 Jan-Feb;61(1):139-142. Epub 2021 Jul 21 doi: 10.1053/j.jfas.2021.07.008. PMID: 34353730
Gaweł E, Zwierzchowska A
Medicine (Baltimore) 2021 Dec 17;100(50):e28257. doi: 10.1097/MD.0000000000028257. PMID: 34918694Free PMC Article
Bezuglov EN, Tikhonova АА, Chubarovskiy PV, Repetyuk АD, Khaitin VY, Lazarev AM, Usmanova EM
Int Orthop 2020 Sep;44(9):1737-1743. Epub 2020 Apr 28 doi: 10.1007/s00264-020-04572-3. PMID: 32346752
Janoyer M
Orthop Traumatol Surg Res 2019 Feb;105(1S):S111-S121. Epub 2018 Feb 23 doi: 10.1016/j.otsr.2018.01.009. PMID: 29481866
Birch JG
J Am Acad Orthop Surg 2013 Jul;21(7):408-18. doi: 10.5435/JAAOS-21-07-408. PMID: 23818028

Recent systematic reviews

Neuhaus C, Appenzeller-Herzog C, Faude O
Phys Ther Sport 2021 May;49:178-187. Epub 2021 Mar 9 doi: 10.1016/j.ptsp.2021.03.002. PMID: 33744766
Banwarie RR, Hollman F, Meijs N, Arts JJ, Vroemen P, Moh P, Staal HM
J Pediatr Orthop B 2020 Jul;29(4):323-336. doi: 10.1097/BPB.0000000000000677. PMID: 31651748
Mixa PJ, Segreto FA, Luigi-Martinez H, Diebo BG, Naziri Q, Kolla S, Maheshwari AV
Surg Technol Int 2017 Dec 12;31:365-373. PMID: 29316596
Pretell-Mazzini J, Kelly DM, Sawyer JR, Esteban EM, Spence DD, Warner WC Jr, Beaty JH
J Pediatr Orthop 2016 Jul-Aug;36(5):440-6. doi: 10.1097/BPO.0000000000000488. PMID: 25887827
Zwingmann J, Südkamp NP, Schmal H, Niemeyer P
Arch Orthop Trauma Surg 2012 Sep;132(9):1241-50. Epub 2012 May 24 doi: 10.1007/s00402-012-1544-1. PMID: 22622794

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...