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Atrial septal defect, ostium primum type

MedGen UID:
1825952
•Concept ID:
C5680294
•
Congenital Abnormality
Synonym: ASD ostium primum type
 
Monarch Initiative: MONDO:0020437
Orphanet: ORPHA99106

Definition

Atrioventricular septal defect with communication at the atrial level only. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAtrial septal defect, ostium primum type

Professional guidelines

PubMed

Clinical utility of repeat fetal echocardiography in congenital heart disease.
Barris DM, Mikhno M, Kornblit M, Wang K, Duong S, Cohen J, Paul E, Stern K, Ezon D, Geiger M
Ultrasound Obstet Gynecol 2023 Nov;62(5):695-700. Epub 2023 Oct 11 doi: 10.1002/uog.26240. PMID: 37128164
Coronary sinus septal defect (unroofed coronary sinus): echocardiographic diagnosis and surgical treatment.
Xie MX, Yang YL, Cheng TO, Wang XF, Li K, Ren PP, Lü Q, Lin H, Li L
Int J Cardiol 2013 Sep 30;168(2):1258-63. Epub 2012 Dec 23 doi: 10.1016/j.ijcard.2012.11.113. PMID: 23266300
Congenital diaphragmatic hernia and associated cardiovascular malformations: type, frequency, and impact on management.
Lin AE, Pober BR, Adatia I
Am J Med Genet C Semin Med Genet 2007 May 15;145C(2):201-16. doi: 10.1002/ajmg.c.30131. PMID: 17436301Free PMC Article

Recent clinical studies

Etiology

Outcome of transcatheter atrial septal defect closure in a nationwide cohort.
Muroke V, Jalanko M, Haukka J, Hartikainen J, Tahvanainen A, Ukkonen H, Ylitalo K, Pihkala J, Sinisalo J
Ann Med 2023 Dec;55(1):615-623. doi: 10.1080/07853890.2023.2178669. PMID: 36786506Free PMC Article
Safety and Efficacy of the Amplatzer Septal Occluder: A Systematic Review and Meta-Analysis.
Heaton JN, Okoh AK, Suh S, Ozturk E, Salemi A, Waxman S, Tayal R
Cardiovasc Revasc Med 2022 Apr;37:52-60. Epub 2021 Jun 17 doi: 10.1016/j.carrev.2021.06.002. PMID: 34183276Free PMC Article
Antiplatelet and Antithrombotic Therapy After Patent Foramen Oval and Atrial Septal Defect Closure.
Drakopoulou M, Soulaidopoulos S, Stathogiannis K, Oikonomou G, Papanikolaou A, Toutouzas K, Tousoulis D
Curr Pharm Des 2020;26(23):2769-2779. doi: 10.2174/1385272824999200427083838. PMID: 32338207
Atrial septal defects.
Geva T, Martins JD, Wald RM
Lancet 2014 May 31;383(9932):1921-32. Epub 2014 Apr 8 doi: 10.1016/S0140-6736(13)62145-5. PMID: 24725467
Pediatric cardiac interventions.
Hijazi ZM, Awad SM
JACC Cardiovasc Interv 2008 Dec;1(6):603-11. doi: 10.1016/j.jcin.2008.07.007. PMID: 19463373

Diagnosis

Holt-Oram syndrome.
Skwarek-Dziekanowska A, Wójtowicz-Ściślak A, Sobieszek G
Eur Rev Med Pharmacol Sci 2024 Jan;28(1):336-341. doi: 10.26355/eurrev_202401_34921. PMID: 38235884
Outcome of transcatheter atrial septal defect closure in a nationwide cohort.
Muroke V, Jalanko M, Haukka J, Hartikainen J, Tahvanainen A, Ukkonen H, Ylitalo K, Pihkala J, Sinisalo J
Ann Med 2023 Dec;55(1):615-623. doi: 10.1080/07853890.2023.2178669. PMID: 36786506Free PMC Article
Sinus venosus defect of the pulmonary vein-type: An easily missed diagnosis.
Metcalf MK, Ghosh RM, Harris MA, Savla JJ, Cohen MS
Echocardiography 2022 Mar;39(3):543-547. Epub 2022 Feb 15 doi: 10.1111/echo.15310. PMID: 35170076
Atrial septal defects.
Geva T, Martins JD, Wald RM
Lancet 2014 May 31;383(9932):1921-32. Epub 2014 Apr 8 doi: 10.1016/S0140-6736(13)62145-5. PMID: 24725467
Complete atrioventricular canal.
Calabrò R, Limongelli G
Orphanet J Rare Dis 2006 Apr 5;1:8. doi: 10.1186/1750-1172-1-8. PMID: 16722604Free PMC Article

Therapy

Outcome of transcatheter atrial septal defect closure in a nationwide cohort.
Muroke V, Jalanko M, Haukka J, Hartikainen J, Tahvanainen A, Ukkonen H, Ylitalo K, Pihkala J, Sinisalo J
Ann Med 2023 Dec;55(1):615-623. doi: 10.1080/07853890.2023.2178669. PMID: 36786506Free PMC Article
Safety and Efficacy of the Amplatzer Septal Occluder: A Systematic Review and Meta-Analysis.
Heaton JN, Okoh AK, Suh S, Ozturk E, Salemi A, Waxman S, Tayal R
Cardiovasc Revasc Med 2022 Apr;37:52-60. Epub 2021 Jun 17 doi: 10.1016/j.carrev.2021.06.002. PMID: 34183276Free PMC Article
Long-term Complications After Transcatheter Atrial Septal Defect Closure: A Review of the Medical Literature.
Jalal Z, Hascoet S, Baruteau AE, Iriart X, Kreitmann B, Boudjemline Y, Thambo JB
Can J Cardiol 2016 Nov;32(11):1315.e11-1315.e18. Epub 2016 Mar 3 doi: 10.1016/j.cjca.2016.02.068. PMID: 27179546
Pediatric cardiac interventions.
Hijazi ZM, Awad SM
JACC Cardiovasc Interv 2008 Dec;1(6):603-11. doi: 10.1016/j.jcin.2008.07.007. PMID: 19463373
Atrial septal defect: spectrum of care.
Kharouf R, Luxenberg DM, Khalid O, Abdulla R
Pediatr Cardiol 2008 Mar;29(2):271-80. Epub 2007 Oct 23 doi: 10.1007/s00246-007-9052-8. PMID: 17955282

Prognosis

Outcome of transcatheter atrial septal defect closure in a nationwide cohort.
Muroke V, Jalanko M, Haukka J, Hartikainen J, Tahvanainen A, Ukkonen H, Ylitalo K, Pihkala J, Sinisalo J
Ann Med 2023 Dec;55(1):615-623. doi: 10.1080/07853890.2023.2178669. PMID: 36786506Free PMC Article
Long-term Complications After Transcatheter Atrial Septal Defect Closure: A Review of the Medical Literature.
Jalal Z, Hascoet S, Baruteau AE, Iriart X, Kreitmann B, Boudjemline Y, Thambo JB
Can J Cardiol 2016 Nov;32(11):1315.e11-1315.e18. Epub 2016 Mar 3 doi: 10.1016/j.cjca.2016.02.068. PMID: 27179546
Atrial septal defects.
Geva T, Martins JD, Wald RM
Lancet 2014 May 31;383(9932):1921-32. Epub 2014 Apr 8 doi: 10.1016/S0140-6736(13)62145-5. PMID: 24725467
Atrial septal defect: spectrum of care.
Kharouf R, Luxenberg DM, Khalid O, Abdulla R
Pediatr Cardiol 2008 Mar;29(2):271-80. Epub 2007 Oct 23 doi: 10.1007/s00246-007-9052-8. PMID: 17955282
Complete atrioventricular canal.
Calabrò R, Limongelli G
Orphanet J Rare Dis 2006 Apr 5;1:8. doi: 10.1186/1750-1172-1-8. PMID: 16722604Free PMC Article

Clinical prediction guides

Monitoring for atrial fibrillation prior to patent foramen ovale closure after cryptogenic stroke.
Diener HC, Wachter R, Wong A, Thijs V, Schnabel RB, Ntaios G, Kasner S, Rothwell PM, Passman R, Saver JL, Albers BA, Bernstein RA
Int J Stroke 2023 Apr;18(4):400-407. Epub 2022 Sep 19 doi: 10.1177/17474930221124412. PMID: 36050817Free PMC Article
Right-to-Left Shunt Through Iatrogenic Atrial Septal Defect After MitraClip Procedure.
Morikawa T, Miyasaka M, Flint N, Manabe O, Dawkins S, Cheng R, Hussaini A, Makar M, Kar S, Nakamura M
JACC Cardiovasc Interv 2020 Jul 13;13(13):1544-1553. doi: 10.1016/j.jcin.2020.03.056. PMID: 32646695
Identification of candidates for PFO closure in the echocardiography laboratory.
Kerut EK, Campbell WF, Hall ME, McMullan MR
Echocardiography 2018 Nov;35(11):1860-1867. Epub 2018 Oct 10 doi: 10.1111/echo.14154. PMID: 30303254
Outcome of prenatally diagnosed fetal heterotaxy: systematic review and meta-analysis.
Buca DIP, Khalil A, Rizzo G, Familiari A, Di Giovanni S, Liberati M, Murgano D, Ricciardulli A, Fanfani F, Scambia G, D'Antonio F
Ultrasound Obstet Gynecol 2018 Mar;51(3):323-330. doi: 10.1002/uog.17546. PMID: 28603940
Congenital diaphragmatic hernia and associated cardiovascular malformations: type, frequency, and impact on management.
Lin AE, Pober BR, Adatia I
Am J Med Genet C Semin Med Genet 2007 May 15;145C(2):201-16. doi: 10.1002/ajmg.c.30131. PMID: 17436301Free PMC Article

Recent systematic reviews

Incidence of cardiac anomalies in congenital vertebral deformity: systematic review and meta-analysis of 2910 patients.
Bas JL, Pérez S, Rubio P, Mariscal G, Bonilla F, Bovea M, Bas P, Bas T
Eur Spine J 2023 Sep;32(9):2967-2974. Epub 2023 Jun 9 doi: 10.1007/s00586-023-07817-y. PMID: 37294359
Cardiac anomalies in children with congenital duodenal obstruction: a systematic review with meta-analysis.
Pijpers AGH, Eeftinck Schattenkerk LD, de Vries R, Broers CJM, Straver B, van Heurn ELW, Musters GD, Gorter RR, Derikx JPM
Pediatr Surg Int 2023 Mar 26;39(1):160. doi: 10.1007/s00383-023-05449-3. PMID: 36967411Free PMC Article
Sufficient versus deficient rims during percutaneous closure of ostium secundum type atrial septal defect: A systematic review and meta-analysis.
Contreras AE, Ledesma F, Peirone AR, Juaneda E, Defago V, Cuestas E
Indian Heart J 2023 Mar-Apr;75(2):145-152. Epub 2023 Feb 1 doi: 10.1016/j.ihj.2023.01.008. PMID: 36736460Free PMC Article
Safety and Efficacy of the Amplatzer Septal Occluder: A Systematic Review and Meta-Analysis.
Heaton JN, Okoh AK, Suh S, Ozturk E, Salemi A, Waxman S, Tayal R
Cardiovasc Revasc Med 2022 Apr;37:52-60. Epub 2021 Jun 17 doi: 10.1016/j.carrev.2021.06.002. PMID: 34183276Free PMC Article
Outcome of prenatally diagnosed fetal heterotaxy: systematic review and meta-analysis.
Buca DIP, Khalil A, Rizzo G, Familiari A, Di Giovanni S, Liberati M, Murgano D, Ricciardulli A, Fanfani F, Scambia G, D'Antonio F
Ultrasound Obstet Gynecol 2018 Mar;51(3):323-330. doi: 10.1002/uog.17546. PMID: 28603940

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