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Tumor Associated Fever

MedGen UID:
182683
•Concept ID:
C0948348
•
Neoplastic Process
Synonym: Tumor-Associated Fever

Definition

Non-infectious pyrexia secondary to malignancy; it may be attributable to cytokines elaborated by neoplasms, and is a diagnosis of exclusion. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTumor Associated Fever

Professional guidelines

PubMed

Immunomodulatory activities of pixatimod: emerging nonclinical and clinical data, and its potential utility in combination with PD-1 inhibitors.
Hammond E, Haynes NM, Cullinane C, Brennan TV, Bampton D, Handley P, Karoli T, Lanksheer F, Lin L, Yang Y, Dredge K
J Immunother Cancer 2018 Jun 14;6(1):54. doi: 10.1186/s40425-018-0363-5. PMID: 29898788Free PMC Article
Suicidal death of erythrocytes in cancer and its chemotherapy: A potential target in the treatment of tumor-associated anemia.
Lang E, Bissinger R, Qadri SM, Lang F
Int J Cancer 2017 Oct 15;141(8):1522-1528. Epub 2017 Jun 21 doi: 10.1002/ijc.30800. PMID: 28542880
Current management strategies for hypercalcemia.
Pecherstorfer M, Brenner K, Zojer N
Treat Endocrinol 2003;2(4):273-92. doi: 10.2165/00024677-200302040-00005. PMID: 15966562

Recent clinical studies

Etiology

Procalcitonin: a useful discriminator between febrile conditions of different origin in hemato-oncological patients?
Schüttrumpf S, Binder L, Hagemann T, Berkovic D, Trümper L, Binder C
Ann Hematol 2003 Feb;82(2):98-103. Epub 2003 Feb 5 doi: 10.1007/s00277-002-0584-y. PMID: 12601488
A prospective study of daily measurement of C-reactive protein in serum of adults with neutropenia.
Manian FA
Clin Infect Dis 1995 Jul;21(1):114-21. doi: 10.1093/clinids/21.1.114. PMID: 7578719
Tumor-associated fever in breast cancer.
Chawla SP, Buzdar AU, Hortobagyi GN, Blumenschein GR
Cancer 1984 Apr 1;53(7):1596-9. doi: 10.1002/1097-0142(19840401)53:7<1596::aid-cncr2820530729>3.0.co;2-s. PMID: 6697296

Diagnosis

Procalcitonin: a useful discriminator between febrile conditions of different origin in hemato-oncological patients?
Schüttrumpf S, Binder L, Hagemann T, Berkovic D, Trümper L, Binder C
Ann Hematol 2003 Feb;82(2):98-103. Epub 2003 Feb 5 doi: 10.1007/s00277-002-0584-y. PMID: 12601488
A prospective study of daily measurement of C-reactive protein in serum of adults with neutropenia.
Manian FA
Clin Infect Dis 1995 Jul;21(1):114-21. doi: 10.1093/clinids/21.1.114. PMID: 7578719
Tumor-associated fever in breast cancer.
Chawla SP, Buzdar AU, Hortobagyi GN, Blumenschein GR
Cancer 1984 Apr 1;53(7):1596-9. doi: 10.1002/1097-0142(19840401)53:7<1596::aid-cncr2820530729>3.0.co;2-s. PMID: 6697296
Endogenous pyrogen production by Hodgkin's disease and human histiocytic lymphoma cell lines in vitro.
Bodel P, Ralph P, Wenc K, Long JC
J Clin Invest 1980 Feb;65(2):514-8. doi: 10.1172/JCI109695. PMID: 6985918Free PMC Article

Therapy

Procalcitonin: a useful discriminator between febrile conditions of different origin in hemato-oncological patients?
Schüttrumpf S, Binder L, Hagemann T, Berkovic D, Trümper L, Binder C
Ann Hematol 2003 Feb;82(2):98-103. Epub 2003 Feb 5 doi: 10.1007/s00277-002-0584-y. PMID: 12601488
A prospective study of daily measurement of C-reactive protein in serum of adults with neutropenia.
Manian FA
Clin Infect Dis 1995 Jul;21(1):114-21. doi: 10.1093/clinids/21.1.114. PMID: 7578719
Tumor-associated fever in breast cancer.
Chawla SP, Buzdar AU, Hortobagyi GN, Blumenschein GR
Cancer 1984 Apr 1;53(7):1596-9. doi: 10.1002/1097-0142(19840401)53:7<1596::aid-cncr2820530729>3.0.co;2-s. PMID: 6697296

Prognosis

A prospective study of daily measurement of C-reactive protein in serum of adults with neutropenia.
Manian FA
Clin Infect Dis 1995 Jul;21(1):114-21. doi: 10.1093/clinids/21.1.114. PMID: 7578719
Fever in multiple myeloma.
Gross DJ, Shalit M, Levo Y
Isr J Med Sci 1982 Aug;18(8):870-2. PMID: 7118534

Clinical prediction guides

A prospective study of daily measurement of C-reactive protein in serum of adults with neutropenia.
Manian FA
Clin Infect Dis 1995 Jul;21(1):114-21. doi: 10.1093/clinids/21.1.114. PMID: 7578719

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