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Myocardial bridging

MedGen UID:
182684
•Concept ID:
C0948355
•
Disease or Syndrome
Synonyms: Bridging, Myocardial; Bridgings, Myocardial; Myocardial Bridging; Myocardial Bridgings
 
HPO: HP:0025490
Monarch Initiative: MONDO:0020421

Definition

A congenital variant of a coronary artery in which a portion of an epicardial coronary artery (most frequently the middle segment of the left anterior descending artery) takes an intramuscular course. [from HPO]

Professional guidelines

PubMed

Clinical Implication and Optimal Management of Myocardial Bridging: Role of Cardiovascular Imaging.
Hashikata T, Kameda R, Ako J
Interv Cardiol Clin 2023 Apr;12(2):281-288. Epub 2023 Jan 31 doi: 10.1016/j.iccl.2022.12.007. PMID: 36922068
Myocardial Bridging: Diagnosis, Functional Assessment, and Management: JACC State-of-the-Art Review.
Sternheim D, Power DA, Samtani R, Kini A, Fuster V, Sharma S
J Am Coll Cardiol 2021 Nov 30;78(22):2196-2212. doi: 10.1016/j.jacc.2021.09.859. PMID: 34823663
Challenges in Evaluation and Management of Children with Myocardial Bridging.
Erol N
Cardiology 2021;146(3):273-280. Epub 2021 Feb 25 doi: 10.1159/000513900. PMID: 33631747

Recent clinical studies

Etiology

Myocardial bridging is significantly associated to myocardial infarction with non-obstructive coronary arteries.
Matta A, Nader V, Canitrot R, Delmas C, Bouisset F, Lhermusier T, Blanco S, Campelo-Parada F, Elbaz M, Carrie D, Galinier M, Roncalli J
Eur Heart J Acute Cardiovasc Care 2022 Jun 22;11(6):501-507. doi: 10.1093/ehjacc/zuac047. PMID: 35511689
Challenges in Evaluation and Management of Children with Myocardial Bridging.
Erol N
Cardiology 2021;146(3):273-280. Epub 2021 Feb 25 doi: 10.1159/000513900. PMID: 33631747
Stable coronary syndromes: pathophysiology, diagnostic advances and therapeutic need.
Ford TJ, Corcoran D, Berry C
Heart 2018 Feb;104(4):284-292. Epub 2017 Oct 13 doi: 10.1136/heartjnl-2017-311446. PMID: 29030424Free PMC Article
Myocardial bridging: a review with emphasis on electrocardiographic findings.
Rovai D, Di Bella G, Pingitore A, Coceani M
Ann Noninvasive Electrocardiol 2015 Mar;20(2):103-7. Epub 2014 Dec 22 doi: 10.1111/anec.12242. PMID: 25530097Free PMC Article
Myocardial bridging and prognosis: more evidence but jury still out.
Tarantini G, Cademartiri F
Eur Heart J Cardiovasc Imaging 2013 Jun;14(6):515-7. Epub 2013 Feb 14 doi: 10.1093/ehjci/jet021. PMID: 23413082

Diagnosis

Myocardial Bridging: Diagnosis, Functional Assessment, and Management: JACC State-of-the-Art Review.
Sternheim D, Power DA, Samtani R, Kini A, Fuster V, Sharma S
J Am Coll Cardiol 2021 Nov 30;78(22):2196-2212. doi: 10.1016/j.jacc.2021.09.859. PMID: 34823663
Challenges in Evaluation and Management of Children with Myocardial Bridging.
Erol N
Cardiology 2021;146(3):273-280. Epub 2021 Feb 25 doi: 10.1159/000513900. PMID: 33631747
An Updated Review on Myocardial Bridging.
Murtaza G, Mukherjee D, Gharacholou SM, Nanjundappa A, Lavie CJ, Khan AA, Shanmugasundaram M, Paul TK
Cardiovasc Revasc Med 2020 Sep;21(9):1169-1179. Epub 2020 Feb 18 doi: 10.1016/j.carrev.2020.02.014. PMID: 32173330
Myocardial bridge.
Tiryakioğlu M, Aliyu MN
Folia Morphol (Warsz) 2020;79(2):411-414. Epub 2019 Aug 26 doi: 10.5603/FM.a2019.0080. PMID: 31448810
Stable coronary syndromes: pathophysiology, diagnostic advances and therapeutic need.
Ford TJ, Corcoran D, Berry C
Heart 2018 Feb;104(4):284-292. Epub 2017 Oct 13 doi: 10.1136/heartjnl-2017-311446. PMID: 29030424Free PMC Article

Therapy

Myocardial bridging is associated with exercise-induced ventricular arrhythmia and increases in QT dispersion.
Nishikii-Tachibana M, Pargaonkar VS, Schnittger I, Haddad F, Rogers IS, Tremmel JA, Wang PJ
Ann Noninvasive Electrocardiol 2018 Mar;23(2):e12492. Epub 2017 Sep 18 doi: 10.1111/anec.12492. PMID: 28921787Free PMC Article
Acquired and congenital coronary artery abnormalities.
Young ML, McLeary M, Chan KC
Cardiol Young 2017 Jan;27(S1):S31-S35. doi: 10.1017/S1047951116002201. PMID: 28084958
Isolated myocardial bridging and exercise-related cardiac events.
Gowd BM, Thompson PD
Int J Sports Med 2014 Dec;35(14):1145-50. Epub 2014 Aug 21 doi: 10.1055/s-0034-1370912. PMID: 25144435
Relationship between myocardial bridging and coronary arteriosclerosis.
Sun JL, Huang WM, Guo JH, Li XY, Ma XL, Wang CY
Cell Biochem Biophys 2013 Apr;65(3):485-9. doi: 10.1007/s12013-012-9438-y. PMID: 23076634
Myocardial bridging.
Alegria JR, Herrmann J, Holmes DR Jr, Lerman A, Rihal CS
Eur Heart J 2005 Jun;26(12):1159-68. Epub 2005 Mar 11 doi: 10.1093/eurheartj/ehi203. PMID: 15764618

Prognosis

Relationship Between Coronary Atheroma, Epicardial Adipose Tissue Inflammation, and Adipocyte Differentiation Across the Human Myocardial Bridge.
McLaughlin T, Schnittger I, Nagy A, Zanley E, Xu Y, Song Y, Nieman K, Tremmel JA, Dey D, Boyd J, Sacks H
J Am Heart Assoc 2021 Nov 16;10(22):e021003. Epub 2021 Nov 2 doi: 10.1161/JAHA.121.021003. PMID: 34726081Free PMC Article
An Updated Review on Myocardial Bridging.
Murtaza G, Mukherjee D, Gharacholou SM, Nanjundappa A, Lavie CJ, Khan AA, Shanmugasundaram M, Paul TK
Cardiovasc Revasc Med 2020 Sep;21(9):1169-1179. Epub 2020 Feb 18 doi: 10.1016/j.carrev.2020.02.014. PMID: 32173330
Non-atherosclerotic causes of acute coronary syndromes.
Waterbury TM, Tarantini G, Vogel B, Mehran R, Gersh BJ, Gulati R
Nat Rev Cardiol 2020 Apr;17(4):229-241. Epub 2019 Oct 3 doi: 10.1038/s41569-019-0273-3. PMID: 31582839
Myocardial bridging: a review with emphasis on electrocardiographic findings.
Rovai D, Di Bella G, Pingitore A, Coceani M
Ann Noninvasive Electrocardiol 2015 Mar;20(2):103-7. Epub 2014 Dec 22 doi: 10.1111/anec.12242. PMID: 25530097Free PMC Article
Myocardial bridging and prognosis: more evidence but jury still out.
Tarantini G, Cademartiri F
Eur Heart J Cardiovasc Imaging 2013 Jun;14(6):515-7. Epub 2013 Feb 14 doi: 10.1093/ehjci/jet021. PMID: 23413082

Clinical prediction guides

Myocardial bridging is significantly associated to myocardial infarction with non-obstructive coronary arteries.
Matta A, Nader V, Canitrot R, Delmas C, Bouisset F, Lhermusier T, Blanco S, Campelo-Parada F, Elbaz M, Carrie D, Galinier M, Roncalli J
Eur Heart J Acute Cardiovasc Care 2022 Jun 22;11(6):501-507. doi: 10.1093/ehjacc/zuac047. PMID: 35511689
Acquired and congenital coronary artery abnormalities.
Young ML, McLeary M, Chan KC
Cardiol Young 2017 Jan;27(S1):S31-S35. doi: 10.1017/S1047951116002201. PMID: 28084958
High Prevalence and Clinical Implication of Myocardial Bridging in Patients with Early Repolarization.
Seo J, Park J, Oh J, Uhm JS, Sung JH, Kim JY, Pak HN, Lee MH, Joung B
Yonsei Med J 2017 Jan;58(1):67-74. doi: 10.3349/ymj.2017.58.1.67. PMID: 27873497Free PMC Article
Myocardial bridging: a review with emphasis on electrocardiographic findings.
Rovai D, Di Bella G, Pingitore A, Coceani M
Ann Noninvasive Electrocardiol 2015 Mar;20(2):103-7. Epub 2014 Dec 22 doi: 10.1111/anec.12242. PMID: 25530097Free PMC Article
Myocardial bridging: therapeutic and clinical development.
Pereira AB, Castro DS, Menegotto ET, Amaral WM, Castro GS
Arq Bras Cardiol 2010 Feb;94(2):175-81, 188-94, 178-84. doi: 10.1590/s0066-782x2010000200008. PMID: 20428612

Recent systematic reviews

Systematic Review and Meta-Analysis of Cardiovascular Consequences of Myocardial Bridging in Hypertrophic Cardiomyopathy.
Bruce C, Ubhi N, McKeegan P, Sanders K
Am J Cardiol 2023 Feb 1;188:110-119. Epub 2022 Dec 10 doi: 10.1016/j.amjcard.2022.10.059. PMID: 36512852
Life-threatening and major cardiac events during long-distance races: updates from the prospective RACE PARIS registry with a systematic review and meta-analysis.
Gerardin B, Guedeney P, Bellemain-Appaix A, Levasseur T, Mustafic H, Benamer H, Monsegu J, Lamhaut L, Montalescot G, Aubry P, Collet JP; Groupe de Réflexions sur la Cardiologie Interventionnelle
Eur J Prev Cardiol 2021 May 22;28(6):679-686. Epub 2020 Jul 27 doi: 10.1177/2047487320943001. PMID: 34021577
Myocardial bridges: A meta-analysis.
Roberts W, Charles SM, Ang C, Holda MK, Walocha J, Lachman N, Tubbs RS, Loukas M
Clin Anat 2021 Jul;34(5):685-709. Epub 2021 Feb 22 doi: 10.1002/ca.23697. PMID: 33078444
Spontaneous coronary artery dissection and associated myocardial bridging: Current evidence from cohort study and case reports.
Tajrishi FZ, Ahmad A, Jamil A, Sharfaei S, Goudarzi S, Homayounieh F, Pitliya A, Kahe F, Chi G
Med Hypotheses 2019 Jul;128:50-53. Epub 2019 May 13 doi: 10.1016/j.mehy.2019.05.012. PMID: 31203908
What is the optimal treatment for symptomatic patients with isolated coronary myocardial bridge? A systematic review and pooled analysis.
Cerrato E, Barbero U, D'Ascenzo F, Taha S, Biondi-Zoccai G, Omedè P, Bianco M, Echavarria-Pinto M, Escaned J, Gaita F, Varbella F
J Cardiovasc Med (Hagerstown) 2017 Oct;18(10):758-770. doi: 10.2459/JCM.0000000000000551. PMID: 28834785

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