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Urethral Infection

MedGen UID:
182685
•Concept ID:
C0948357
•
Disease or Syndrome

Definition

A bacterial, viral, or fungal infectious process affecting the urethra. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUrethral Infection

Professional guidelines

PubMed

Management of urethral atrophy after implantation of artificial urinary sphincter: what are the weaknesses?
Heah NH, Tan RBW
Asian J Androl 2020 Jan-Feb;22(1):60-63. doi: 10.4103/aja.aja_110_19. PMID: 31736473Free PMC Article
Differential diagnosis of chronic pelvic pain in women: the urologist's approach.
Fletcher SG, Zimmern PE
Nat Rev Urol 2009 Oct;6(10):557-62. Epub 2009 Sep 1 doi: 10.1038/nrurol.2009.178. PMID: 19724247
Catheterization: possible complications and their prevention and treatment.
Igawa Y, Wyndaele JJ, Nishizawa O
Int J Urol 2008 Jun;15(6):481-5. Epub 2008 Apr 22 doi: 10.1111/j.1442-2042.2008.02075.x. PMID: 18430150

Recent clinical studies

Etiology

Prevalence and factors associated with gonorrhea infection with respect to anatomic distributions among men who have sex with men.
Budkaew J, Chumworathayi B, Pientong C, Ekalaksananan T
PLoS One 2019;14(4):e0211682. Epub 2019 Apr 3 doi: 10.1371/journal.pone.0211682. PMID: 30943191Free PMC Article
The prevalence of urethral and rectal Mycoplasma genitalium and its associations in men who have sex with men attending a genitourinary medicine clinic.
Soni S, Alexander S, Verlander N, Saunders P, Richardson D, Fisher M, Ison C
Sex Transm Infect 2010 Feb;86(1):21-4. Epub 2009 Oct 19 doi: 10.1136/sti.2009.038190. PMID: 19843536
Associations between condom use and rectal or urethral chlamydia infection in men.
Hocking J, Fairley CK
Sex Transm Dis 2006 Apr;33(4):256-8. doi: 10.1097/01.olq.0000187209.02413.0c. PMID: 16505741
The prevalence of genital Chlamydia trachomatis in Australia 1997-2004: a systematic review.
Vajdic CM, Middleton M, Bowden FJ, Fairley CK, Kaldor JM
Sex Health 2005;2(3):169-83. doi: 10.1071/sh05018. PMID: 16335545
Screening for urethral infection in adolescent and young adult males.
Johnson J, Neas B, Parker DE, Fortenberry JD, Cowan LD
J Adolesc Health 1993 Jul;14(5):356-61. doi: 10.1016/s1054-139x(08)80007-9. PMID: 8399246

Diagnosis

Modelling the in-host dynamics of Neisseria gonorrhoeae infection.
Jayasundara P, Regan DG, Seib KL, Jayasundara D, Wood JG
Pathog Dis 2019 Feb 1;77(1) doi: 10.1093/femspd/ftz008. PMID: 30770529
The prevalence of genital Chlamydia trachomatis in Australia 1997-2004: a systematic review.
Vajdic CM, Middleton M, Bowden FJ, Fairley CK, Kaldor JM
Sex Health 2005;2(3):169-83. doi: 10.1071/sh05018. PMID: 16335545
Pathophysiology of priapism: dysregulatory erection physiology thesis.
Burnett AL
J Urol 2003 Jul;170(1):26-34. doi: 10.1097/01.ju.0000046303.22757.f2. PMID: 12796638
Syndromic management of sexually transmitted diseases. Part 2--The management of genital discharge.
Latif AS
Cent Afr J Med 1998 Sep;44(9):236-41. PMID: 10101431
Nongonococcal urethritis.
Handsfield HH
Cutis 1981 Mar;27(3):268-70, 275-7. PMID: 7214998

Therapy

New Approach to Microscopy of Gram-Stained Urethral Smear: The Kissing Slide Method.
Sarier M, Demir M, Turgut H, Hizel A, Emek M, Kukul E, Sepin N
Sex Transm Dis 2020 Oct;47(10):712-715. doi: 10.1097/OLQ.0000000000001228. PMID: 32649578
Asymptomatic Chlamydia trachomatis urethritis in men.
Stamm WE, Cole B
Sex Transm Dis 1986 Jul-Sep;13(3):163-5. doi: 10.1097/00007435-198607000-00010. PMID: 3764626
Treatment of uncomplicated gonorrhea with cefotaxime.
Handsfield HH
Rev Infect Dis 1982 Sep-Oct;4 Suppl:S448-52. doi: 10.1093/clinids/4.supplement_2.s448. PMID: 6294798
Nongonococcal urethritis.
Handsfield HH
Cutis 1981 Mar;27(3):268-70, 275-7. PMID: 7214998
Etiology and treatment of nongonococcal urethritis.
Bowie WR
Sex Transm Dis 1978 Jan-Mar;5(1):27-33. doi: 10.1097/00007435-197801000-00009. PMID: 644417

Prognosis

Urethral infection in a workplace population of East African men: evaluation of strategies for screening and management.
Jackson DJ, Rakwar JP, Chohan B, Mandaliya K, Bwayo JJ, Ndinya-Achola JO, Nagelkerke NJ, Kreiss JK, Moses S
J Infect Dis 1997 Apr;175(4):833-8. doi: 10.1086/513979. PMID: 9086138
Evaluation of urine-based screening strategies to detect Chlamydia trachomatis among sexually active asymptomatic young males.
Shafer MA, Schachter J, Moncada J, Keogh J, Pantell R, Gourlay L, Eyre S, Boyer CB
JAMA 1993 Nov 3;270(17):2065-70. PMID: 8411573
Screening for urethral infection in adolescent and young adult males.
Johnson J, Neas B, Parker DE, Fortenberry JD, Cowan LD
J Adolesc Health 1993 Jul;14(5):356-61. doi: 10.1016/s1054-139x(08)80007-9. PMID: 8399246
Diagnosis of Chlamydia trachomatis urethritis in men by polymerase chain reaction assay of first-catch urine.
Bauwens JE, Clark AM, Loeffelholz MJ, Herman SA, Stamm WE
J Clin Microbiol 1993 Nov;31(11):3013-6. doi: 10.1128/jcm.31.11.3013-3016.1993. PMID: 8263188Free PMC Article
Urinary infection in boys.A three-year prospective study.
Hallett RJ, Pead L, Maskell R
Lancet 1976 Nov 20;2(7995):1107-10. doi: 10.1016/s0140-6736(76)91087-4. PMID: 62948

Clinical prediction guides

Epidemiological, clinical and laboratory differences between male urethral infections due to Haemophilus spp. and those due to Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium and Ureaplasma urealyticum: A descriptive study.
Vives A, Cosentino M, Bassas L, Alonso C, Millan F
Arch Ital Urol Androl 2021 Dec 21;93(4):468-474. doi: 10.4081/aiua.2021.4.468. PMID: 34933533
Modelling the in-host dynamics of Neisseria gonorrhoeae infection.
Jayasundara P, Regan DG, Seib KL, Jayasundara D, Wood JG
Pathog Dis 2019 Feb 1;77(1) doi: 10.1093/femspd/ftz008. PMID: 30770529
Pathophysiology of priapism: dysregulatory erection physiology thesis.
Burnett AL
J Urol 2003 Jul;170(1):26-34. doi: 10.1097/01.ju.0000046303.22757.f2. PMID: 12796638
Urethral infection in a workplace population of East African men: evaluation of strategies for screening and management.
Jackson DJ, Rakwar JP, Chohan B, Mandaliya K, Bwayo JJ, Ndinya-Achola JO, Nagelkerke NJ, Kreiss JK, Moses S
J Infect Dis 1997 Apr;175(4):833-8. doi: 10.1086/513979. PMID: 9086138
Screening for urethral infection in adolescent and young adult males.
Johnson J, Neas B, Parker DE, Fortenberry JD, Cowan LD
J Adolesc Health 1993 Jul;14(5):356-61. doi: 10.1016/s1054-139x(08)80007-9. PMID: 8399246

Recent systematic reviews

The prevalence of genital Chlamydia trachomatis in Australia 1997-2004: a systematic review.
Vajdic CM, Middleton M, Bowden FJ, Fairley CK, Kaldor JM
Sex Health 2005;2(3):169-83. doi: 10.1071/sh05018. PMID: 16335545

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