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Bone marrow myeloid vacuolization

MedGen UID:
1841590
Concept ID:
C5826546
Finding
Synonyms: Bone marrow: myeloid vacuolization; Vacuolization of bone marrow myeloid precursors
 
HPO: HP:0034636

Definition

Formation of vacuoles (a space within a cell that is empty of cytoplasm, lined with a membrane, and filled with fluid) in the cytoplasm of myeloid precursors in the bone marrow. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBone marrow myeloid vacuolization

Professional guidelines

PubMed

Loeza-Uribe MP, Hinojosa-Azaola A, Sánchez-Hernández BE, Crispín JC, Apodaca-Chávez E, Ferrada MA, Martín-Nares E
Reumatol Clin (Engl Ed) 2024 Jan;20(1):47-56. Epub 2023 Dec 29 doi: 10.1016/j.reumae.2023.12.004. PMID: 38160120
Koster MJ, Lasho TL, Olteanu H, Reichard KK, Mangaonkar A, Warrington KJ, Patnaik MM
Am J Hematol 2024 Feb;99(2):284-299. Epub 2023 Nov 11 doi: 10.1002/ajh.27156. PMID: 37950858
Chabrun F, Lacombe V, Dieu X, Geneviève F, Urbanski G
Clin Chem Lab Med 2023 Jun 27;61(7):1275-1279. Epub 2023 Feb 2 doi: 10.1515/cclm-2022-1283. PMID: 36722042

Recent clinical studies

Etiology

Baur V, Stoevesandt J, Hueber A, Hüffmeier U, Kneitz H, Morbach H, Schultz E, Goebeler M
J Dtsch Dermatol Ges 2023 Dec;21(12):1456-1463. Epub 2023 Nov 12 doi: 10.1111/ddg.15227. PMID: 37953404
Hines AS, Koster MJ, Bock AR, Go RS, Warrington KJ, Olteanu H, Lasho TL, Patnaik MM, Reichard KK
Rheumatology (Oxford) 2023 Dec 1;62(12):3947-3951. doi: 10.1093/rheumatology/kead245. PMID: 37228016
Kunimoto H, Miura A, Maeda A, Tsuchida N, Uchiyama Y, Kunishita Y, Nakajima Y, Takase-Minegishi K, Yoshimi R, Miyazaki T, Hagihara M, Yamazaki E, Kirino Y, Matsumoto N, Nakajima H
Int J Hematol 2023 Oct;118(4):494-502. Epub 2023 Apr 17 doi: 10.1007/s12185-023-03598-8. PMID: 37062784
Zakine E, Schell B, Battistella M, Vignon-Pennamen MD, Chasset F, Mahévas T, Cordoliani F, Adès L, Sébert M, Delaleu J, Jachiet M, Lepelletier C, Lemaire P, Chauvel C, Dhouaieb B, Kim R, Cassius C, Georgin-Lavialle S, Mekinian A, Bagot M, Braun T, Rousset L, Begon E, de Masson A, Fenaux P, Clappier E, Bouaziz JD
JAMA Dermatol 2021 Nov 1;157(11):1349-1354. doi: 10.1001/jamadermatol.2021.3344. PMID: 34495287Free PMC Article
Obiorah IE, Patel BA, Groarke EM, Wang W, Trick M, Ombrello AK, Ferrada MA, Wu Z, Gutierrez-Rodrigues F, Lotter J, Wilson L, Hoffmann P, Cardona DO, Patel N, Dulau-Florea A, Kastner DL, Grayson PC, Beck DB, Young NS, Calvo KR
Blood Adv 2021 Aug 24;5(16):3203-3215. doi: 10.1182/bloodadvances.2021004976. PMID: 34427584Free PMC Article

Diagnosis

Koster MJ, Lasho TL, Olteanu H, Reichard KK, Mangaonkar A, Warrington KJ, Patnaik MM
Am J Hematol 2024 Feb;99(2):284-299. Epub 2023 Nov 11 doi: 10.1002/ajh.27156. PMID: 37950858
Cherniawsky H, Friedmann J, Nicolson H, Dehghan N, Stubbins RJ, Foltz LM, Leitch HA, Sreenivasan GM, Ambler KLS, Nevill TJ, McGinnis E, Wilson L, Beck DB, Chen LYC, Marcon KM
Eur J Haematol 2023 Jun;110(6):633-638. Epub 2023 Feb 22 doi: 10.1111/ejh.13944. PMID: 36788756
Yoshimi A, Ishikawa K, Niemeyer C, Grünert SC
Orphanet J Rare Dis 2022 Oct 17;17(1):379. doi: 10.1186/s13023-022-02538-9. PMID: 36253820Free PMC Article
Zakine E, Schell B, Battistella M, Vignon-Pennamen MD, Chasset F, Mahévas T, Cordoliani F, Adès L, Sébert M, Delaleu J, Jachiet M, Lepelletier C, Lemaire P, Chauvel C, Dhouaieb B, Kim R, Cassius C, Georgin-Lavialle S, Mekinian A, Bagot M, Braun T, Rousset L, Begon E, de Masson A, Fenaux P, Clappier E, Bouaziz JD
JAMA Dermatol 2021 Nov 1;157(11):1349-1354. doi: 10.1001/jamadermatol.2021.3344. PMID: 34495287Free PMC Article
Obiorah IE, Patel BA, Groarke EM, Wang W, Trick M, Ombrello AK, Ferrada MA, Wu Z, Gutierrez-Rodrigues F, Lotter J, Wilson L, Hoffmann P, Cardona DO, Patel N, Dulau-Florea A, Kastner DL, Grayson PC, Beck DB, Young NS, Calvo KR
Blood Adv 2021 Aug 24;5(16):3203-3215. doi: 10.1182/bloodadvances.2021004976. PMID: 34427584Free PMC Article

Therapy

Sharma K, Keri VC, Kumar TP, Sethi P, Dass J, Mishra RK
Trop Doct 2023 Apr;53(2):315-316. Epub 2023 Mar 8 doi: 10.1177/00494755231159292. PMID: 36890727
Kataoka A, Mizumoto C, Kanda J, Iwasaki M, Sakurada M, Oka T, Fujimoto M, Yamamoto Y, Yamashita K, Nannya Y, Ogawa S, Takaori-Kondo A
Int J Hematol 2023 Jun;117(6):919-924. Epub 2023 Jan 14 doi: 10.1007/s12185-023-03532-y. PMID: 36641501
Guerrero-Bermúdez CA, Cardona-Cardona AF, Ariza-Parra EJ, Arostegui JI, Mensa-Vilaro A, Yague J, Vásquez G, Muñoz-Vahos CH
Clin Rheumatol 2022 Nov;41(11):3565-3572. Epub 2022 Aug 20 doi: 10.1007/s10067-022-06338-1. PMID: 35986821
Mayer LD, Tardi P, Louie AC
Int J Nanomedicine 2019;14:3819-3830. Epub 2019 May 23 doi: 10.2147/IJN.S139450. PMID: 31213803Free PMC Article
Ryder JW, Lazarus HM, Farhi DC
Am J Clin Pathol 1992 May;97(5):631-7. doi: 10.1093/ajcp/97.5.631. PMID: 1575207

Prognosis

Loeza-Uribe MP, Hinojosa-Azaola A, Sánchez-Hernández BE, Crispín JC, Apodaca-Chávez E, Ferrada MA, Martín-Nares E
Reumatol Clin (Engl Ed) 2024 Jan;20(1):47-56. Epub 2023 Dec 29 doi: 10.1016/j.reumae.2023.12.004. PMID: 38160120
Gurnari C, Pascale MR, Vitale A, Diral E, Tomelleri A, Galossi E, Falconi G, Bruno A, Crisafulli F, Frassi M, Cattaneo C, Bertoli D, Bernardi M, Condorelli A, Morsia E, Poloni A, Crisà E, Caravelli D, Triggianese P, Brussino L, Battipaglia G, Bindoli S, Sfriso P, Caroni F, Dragani M, Mallegni F, Pilo F, Firinu D, Curti A, Papayannidis C, Olivieri A, Kordasti S, Albano F, Pane F, Musto P, Bocchia M, Lugli E, Breccia M, Frigeni M, Dagna L, Greco R, Franceschini F, Campochiaro C, Cantarini L, Voso MT
Am J Hematol 2024 Feb;99(2):254-262. Epub 2023 Dec 18 doi: 10.1002/ajh.27169. PMID: 38108611
Kunimoto H, Miura A, Maeda A, Tsuchida N, Uchiyama Y, Kunishita Y, Nakajima Y, Takase-Minegishi K, Yoshimi R, Miyazaki T, Hagihara M, Yamazaki E, Kirino Y, Matsumoto N, Nakajima H
Int J Hematol 2023 Oct;118(4):494-502. Epub 2023 Apr 17 doi: 10.1007/s12185-023-03598-8. PMID: 37062784
Yoshimi A, Ishikawa K, Niemeyer C, Grünert SC
Orphanet J Rare Dis 2022 Oct 17;17(1):379. doi: 10.1186/s13023-022-02538-9. PMID: 36253820Free PMC Article
Obiorah IE, Patel BA, Groarke EM, Wang W, Trick M, Ombrello AK, Ferrada MA, Wu Z, Gutierrez-Rodrigues F, Lotter J, Wilson L, Hoffmann P, Cardona DO, Patel N, Dulau-Florea A, Kastner DL, Grayson PC, Beck DB, Young NS, Calvo KR
Blood Adv 2021 Aug 24;5(16):3203-3215. doi: 10.1182/bloodadvances.2021004976. PMID: 34427584Free PMC Article

Clinical prediction guides

Lacombe V, Hadjadj J, Georgin-Lavialle S, Lavigne C, Geneviève F, Kosmider O
Lancet Haematol 2024 Feb;11(2):e160-e167. doi: 10.1016/S2352-3026(23)00375-7. PMID: 38302223
Gurnari C, Pascale MR, Vitale A, Diral E, Tomelleri A, Galossi E, Falconi G, Bruno A, Crisafulli F, Frassi M, Cattaneo C, Bertoli D, Bernardi M, Condorelli A, Morsia E, Poloni A, Crisà E, Caravelli D, Triggianese P, Brussino L, Battipaglia G, Bindoli S, Sfriso P, Caroni F, Dragani M, Mallegni F, Pilo F, Firinu D, Curti A, Papayannidis C, Olivieri A, Kordasti S, Albano F, Pane F, Musto P, Bocchia M, Lugli E, Breccia M, Frigeni M, Dagna L, Greco R, Franceschini F, Campochiaro C, Cantarini L, Voso MT
Am J Hematol 2024 Feb;99(2):254-262. Epub 2023 Dec 18 doi: 10.1002/ajh.27169. PMID: 38108611
Kunimoto H, Miura A, Maeda A, Tsuchida N, Uchiyama Y, Kunishita Y, Nakajima Y, Takase-Minegishi K, Yoshimi R, Miyazaki T, Hagihara M, Yamazaki E, Kirino Y, Matsumoto N, Nakajima H
Int J Hematol 2023 Oct;118(4):494-502. Epub 2023 Apr 17 doi: 10.1007/s12185-023-03598-8. PMID: 37062784
Chabrun F, Lacombe V, Dieu X, Geneviève F, Urbanski G
Clin Chem Lab Med 2023 Jun 27;61(7):1275-1279. Epub 2023 Feb 2 doi: 10.1515/cclm-2022-1283. PMID: 36722042
Ryder JW, Lazarus HM, Farhi DC
Am J Clin Pathol 1992 May;97(5):631-7. doi: 10.1093/ajcp/97.5.631. PMID: 1575207

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