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Septate gallbladder

MedGen UID:
1842069
•Concept ID:
C5826439
•
Congenital Abnormality
HPO: HP:0034504

Definition

Septate gallbladder is characterized by the presence of a septum that divides the gallbladder in two chambers. When the septum dividing the gallbladder lies longitudinally it is called bilobed gallbladder and when there is a transverse septum separating the fundus from the rest of the gallbladder it is called an hour-glass gallbladder. [from HPO]

Professional guidelines

PubMed

Prenatal diagnosis of gall bladder anomalies--report of 17 cases.
Bronshtein M, Weiner Z, Abramovici H, Filmar S, Erlik Y, Blumenfeld Z
Prenat Diagn 1993 Sep;13(9):851-61. doi: 10.1002/pd.1970130909. PMID: 8278315

Recent clinical studies

Etiology

Diagnostic and therapeutic ERCP in the pediatric age group.
Issa H, Al-Haddad A, Al-Salem AH
Pediatr Surg Int 2007 Feb;23(2):111-6. Epub 2006 Dec 6 doi: 10.1007/s00383-006-1832-3. PMID: 17149628
Clinical observations on the biliary system in cystic fibrosis.
Isenberg JN, L'Heureux PR, Warwick WJ, Sharp HL
Am J Gastroenterol 1976 Feb;65(2):134-41. PMID: 1274940

Diagnosis

Septate gallbladder: a rare cause of biliary colic.
Finlay B, Neo EL
ANZ J Surg 2022 Nov;92(11):3091-3092. Epub 2022 Feb 16 doi: 10.1111/ans.17556. PMID: 35170840
Type 1 Choledochal Cyst with Ectopic Pancreas and Septate Gallbladder.
Akbari AH, Putra J
Fetal Pediatr Pathol 2022 Apr;41(2):334-337. Epub 2020 Jul 29 doi: 10.1080/15513815.2020.1797962. PMID: 32723208
Diagnostic and therapeutic ERCP in the pediatric age group.
Issa H, Al-Haddad A, Al-Salem AH
Pediatr Surg Int 2007 Feb;23(2):111-6. Epub 2006 Dec 6 doi: 10.1007/s00383-006-1832-3. PMID: 17149628
Septate gallbladder with cholelithiasis: a cause of chronic abdominal pain in a 6-year-old child.
Esper E, Kaufman DB, Crary GS, Snover DC, Leonard AS
J Pediatr Surg 1992 Dec;27(12):1560-2. doi: 10.1016/0022-3468(92)90507-4. PMID: 1469574
Clinical observations on the biliary system in cystic fibrosis.
Isenberg JN, L'Heureux PR, Warwick WJ, Sharp HL
Am J Gastroenterol 1976 Feb;65(2):134-41. PMID: 1274940

Therapy

Extended application of 99mTc-mebrofenin cholescintigraphy with cholecystokinin in the evaluation of abdominal pain of hepatobiliary and gastrointestinal origin.
Krishnamurthy GT, Krishnamurthy S
Nucl Med Commun 2010 May;31(5):346-54. doi: 10.1097/MNM.0b013e32832fa2c0. PMID: 20147863

Clinical prediction guides

Prevalence of cholelithiasis in lion tamarins (Leontopithecus spp.) kept under human care by using abdominal ultrasound.
Felippi DA, Franco PN, Bonatelli SP, da Silva JP, Guimarães VY, Breda MRS, Pagani R, Dos Santos B, Takahira RK, Rahal SC, Mamprim MJ
J Med Primatol 2023 Feb;52(1):17-23. Epub 2022 Aug 26 doi: 10.1111/jmp.12615. PMID: 36028986
Flattened fundus sign of the septate gallbladder.
Doyle TC
Gastrointest Radiol 1984;9(4):345-7. doi: 10.1007/BF01887865. PMID: 6500245
Clinical observations on the biliary system in cystic fibrosis.
Isenberg JN, L'Heureux PR, Warwick WJ, Sharp HL
Am J Gastroenterol 1976 Feb;65(2):134-41. PMID: 1274940

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