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Pulmonary cylindroma

MedGen UID:
1842088
•Concept ID:
C5826547
•
Neoplastic Process
HPO: HP:0034637

Definition

A cylindroma located in the lung. Cylindromas are well-circumscribed, smooth, pale pink nodular tumors, often with arborizing vessels visible. The tumors are slow growing and vary in size from a few millimeters to over 5 mm. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPulmonary cylindroma

Professional guidelines

PubMed

Current diagnosis and treatment of salivary gland-type tumors of the lung.
Horio Y, Kuroda H, Masago K, Matsushita H, Sasaki E, Fujiwara Y
Jpn J Clin Oncol 2024 Mar 9;54(3):229-247. doi: 10.1093/jjco/hyad160. PMID: 38018262
Lenvatinib in Management of Solid Tumors.
Hao Z, Wang P
Oncologist 2020 Feb;25(2):e302-e310. Epub 2019 Oct 14 doi: 10.1634/theoncologist.2019-0407. PMID: 32043789Free PMC Article
Surgical management of lung metastases.
Patrini D, Panagiotopoulos N, Lawrence D, Scarci M
Br J Hosp Med (Lond) 2017 Apr 2;78(4):192-198. doi: 10.12968/hmed.2017.78.4.192. PMID: 28398890

Recent clinical studies

Etiology

Systematic pan-cancer analyses of the potential function of the Golgi scaffold protein PAQR3.
Ling ZN, Hong LL, Wu J, Ling ZQ
Sci Rep 2024 Feb 6;14(1):3030. doi: 10.1038/s41598-024-53489-z. PMID: 38321173Free PMC Article
Comparison of 68Ga-PSMA-HBED-CC and 18F-FDG PET/CT in the Evaluation of Adenoid Cystic Carcinoma-A Prospective Study.
Shamim SA, Kumar N, Arora G, Kumar D, Pathak A, Thakkar A, Sikka K, Singh CA, Kakkar A, Bhalla AS
Clin Nucl Med 2023 Nov 1;48(11):e509-e515. doi: 10.1097/RLU.0000000000004868. PMID: 37812520
Prognosis and management of recurrent and/or metastatic head and neck adenoid cystic carcinoma.
Lorini L, Ardighieri L, Bozzola A, Romani C, Bignotti E, Buglione M, Guerini A, Lombardi D, Deganello A, Tomasoni M, Bonini SA, Sigala S, Farina D, Ravanelli M, Bossi P
Oral Oncol 2021 Apr;115:105213. Epub 2021 Feb 9 doi: 10.1016/j.oraloncology.2021.105213. PMID: 33578204
Extracellular vesicles of carcinoma-associated fibroblasts creates a pre-metastatic niche in the lung through activating fibroblasts.
Kong J, Tian H, Zhang F, Zhang Z, Li J, Liu X, Li X, Liu J, Li X, Jin D, Yang X, Sun B, Guo T, Luo Y, Lu Y, Lin B, Liu T
Mol Cancer 2019 Dec 3;18(1):175. doi: 10.1186/s12943-019-1101-4. PMID: 31796058Free PMC Article
Endobronchial tumours in childhood.
Curtis JM, Lacey D, Smyth R, Carty H
Eur J Radiol 1998 Nov;29(1):11-20. doi: 10.1016/s0720-048x(97)00185-x. PMID: 9934553

Diagnosis

Adenoid Cystic Carcinoma, Clinical Presentation, Current Treatment and Approaches Towards Novel Therapies.
Zupancic M, Näsman A, Friesland S, Dalianis T
Anticancer Res 2024 Apr;44(4):1325-1334. doi: 10.21873/anticanres.16929. PMID: 38537991
Systematic pan-cancer analyses of the potential function of the Golgi scaffold protein PAQR3.
Ling ZN, Hong LL, Wu J, Ling ZQ
Sci Rep 2024 Feb 6;14(1):3030. doi: 10.1038/s41598-024-53489-z. PMID: 38321173Free PMC Article
Malignant and Benign Tracheobronchial Neoplasms: Comprehensive Review with Radiologic, Bronchoscopic, and Pathologic Correlation.
Girvin F, Phan A, Steinberger S, Shostak E, Bessich J, Zhou F, Borczuk A, Brusca-Augello G, Goldberg M, Escalon J
Radiographics 2023 Sep;43(9):e230045. doi: 10.1148/rg.230045. PMID: 37561643
Increased retinoic acid signaling decreases lung metastasis in salivary adenoid cystic carcinoma by inhibiting the noncanonical Notch1 pathway.
Zhou MJ, Yang JJ, Ma TY, Feng GX, Wang XL, Wang LY, Ge YZ, Gao R, Liu HL, Shan L, Kong L, Chen XH
Exp Mol Med 2023 Mar;55(3):597-611. Epub 2023 Mar 6 doi: 10.1038/s12276-023-00957-7. PMID: 36879115Free PMC Article
DNA methylation-based classification of sinonasal tumors.
Jurmeister P, Glöß S, Roller R, Leitheiser M, Schmid S, Mochmann LH, Payá Capilla E, Fritz R, Dittmayer C, Friedrich C, Thieme A, Keyl P, Jarosch A, Schallenberg S, Bläker H, Hoffmann I, Vollbrecht C, Lehmann A, Hummel M, Heim D, Haji M, Harter P, Englert B, Frank S, Hench J, Paulus W, Hasselblatt M, Hartmann W, Dohmen H, Keber U, Jank P, Denkert C, Stadelmann C, Bremmer F, Richter A, Wefers A, Ribbat-Idel J, Perner S, Idel C, Chiariotti L, Della Monica R, Marinelli A, Schüller U, Bockmayr M, Liu J, Lund VJ, Forster M, Lechner M, Lorenzo-Guerra SL, Hermsen M, Johann PD, Agaimy A, Seegerer P, Koch A, Heppner F, Pfister SM, Jones DTW, Sill M, von Deimling A, Snuderl M, Müller KR, Forgó E, Howitt BE, Mertins P, Klauschen F, Capper D
Nat Commun 2022 Nov 28;13(1):7148. doi: 10.1038/s41467-022-34815-3. PMID: 36443295Free PMC Article

Therapy

Artificial intelligence for predictive biomarker discovery in immuno-oncology: a systematic review.
Prelaj A, Miskovic V, Zanitti M, Trovo F, Genova C, Viscardi G, Rebuzzi SE, Mazzeo L, Provenzano L, Kosta S, Favali M, Spagnoletti A, Castelo-Branco L, Dolezal J, Pearson AT, Lo Russo G, Proto C, Ganzinelli M, Giani C, Ambrosini E, Turajlic S, Au L, Koopman M, Delaloge S, Kather JN, de Braud F, Garassino MC, Pentheroudakis G, Spencer C, Pedrocchi ALG
Ann Oncol 2024 Jan;35(1):29-65. Epub 2023 Oct 23 doi: 10.1016/j.annonc.2023.10.125. PMID: 37879443
Lenvatinib in Management of Solid Tumors.
Hao Z, Wang P
Oncologist 2020 Feb;25(2):e302-e310. Epub 2019 Oct 14 doi: 10.1634/theoncologist.2019-0407. PMID: 32043789Free PMC Article
Surgical management of lung metastases.
Patrini D, Panagiotopoulos N, Lawrence D, Scarci M
Br J Hosp Med (Lond) 2017 Apr 2;78(4):192-198. doi: 10.12968/hmed.2017.78.4.192. PMID: 28398890
Chemotherapy and targeted therapy in adenoid cystic carcinoma of the head and neck: a review.
Papaspyrou G, Hoch S, Rinaldo A, Rodrigo JP, Takes RP, van Herpen C, Werner JA, Ferlito A
Head Neck 2011 Jun;33(6):905-11. Epub 2010 Jul 22 doi: 10.1002/hed.21458. PMID: 20652885
Bronchoesophagology.
Putney FJ
Arch Otolaryngol 1970 Sep;92(3):293-8. doi: 10.1001/archotol.1970.04310030083020. PMID: 4324089

Prognosis

Systematic pan-cancer analyses of the potential function of the Golgi scaffold protein PAQR3.
Ling ZN, Hong LL, Wu J, Ling ZQ
Sci Rep 2024 Feb 6;14(1):3030. doi: 10.1038/s41598-024-53489-z. PMID: 38321173Free PMC Article
Artificial intelligence for predictive biomarker discovery in immuno-oncology: a systematic review.
Prelaj A, Miskovic V, Zanitti M, Trovo F, Genova C, Viscardi G, Rebuzzi SE, Mazzeo L, Provenzano L, Kosta S, Favali M, Spagnoletti A, Castelo-Branco L, Dolezal J, Pearson AT, Lo Russo G, Proto C, Ganzinelli M, Giani C, Ambrosini E, Turajlic S, Au L, Koopman M, Delaloge S, Kather JN, de Braud F, Garassino MC, Pentheroudakis G, Spencer C, Pedrocchi ALG
Ann Oncol 2024 Jan;35(1):29-65. Epub 2023 Oct 23 doi: 10.1016/j.annonc.2023.10.125. PMID: 37879443
DNA methylation-based classification of sinonasal tumors.
Jurmeister P, Glöß S, Roller R, Leitheiser M, Schmid S, Mochmann LH, Payá Capilla E, Fritz R, Dittmayer C, Friedrich C, Thieme A, Keyl P, Jarosch A, Schallenberg S, Bläker H, Hoffmann I, Vollbrecht C, Lehmann A, Hummel M, Heim D, Haji M, Harter P, Englert B, Frank S, Hench J, Paulus W, Hasselblatt M, Hartmann W, Dohmen H, Keber U, Jank P, Denkert C, Stadelmann C, Bremmer F, Richter A, Wefers A, Ribbat-Idel J, Perner S, Idel C, Chiariotti L, Della Monica R, Marinelli A, Schüller U, Bockmayr M, Liu J, Lund VJ, Forster M, Lechner M, Lorenzo-Guerra SL, Hermsen M, Johann PD, Agaimy A, Seegerer P, Koch A, Heppner F, Pfister SM, Jones DTW, Sill M, von Deimling A, Snuderl M, Müller KR, Forgó E, Howitt BE, Mertins P, Klauschen F, Capper D
Nat Commun 2022 Nov 28;13(1):7148. doi: 10.1038/s41467-022-34815-3. PMID: 36443295Free PMC Article
Lenvatinib in Management of Solid Tumors.
Hao Z, Wang P
Oncologist 2020 Feb;25(2):e302-e310. Epub 2019 Oct 14 doi: 10.1634/theoncologist.2019-0407. PMID: 32043789Free PMC Article
Extracellular vesicles of carcinoma-associated fibroblasts creates a pre-metastatic niche in the lung through activating fibroblasts.
Kong J, Tian H, Zhang F, Zhang Z, Li J, Liu X, Li X, Liu J, Li X, Jin D, Yang X, Sun B, Guo T, Luo Y, Lu Y, Lin B, Liu T
Mol Cancer 2019 Dec 3;18(1):175. doi: 10.1186/s12943-019-1101-4. PMID: 31796058Free PMC Article

Clinical prediction guides

Adenoid Cystic Carcinoma, Clinical Presentation, Current Treatment and Approaches Towards Novel Therapies.
Zupancic M, Näsman A, Friesland S, Dalianis T
Anticancer Res 2024 Apr;44(4):1325-1334. doi: 10.21873/anticanres.16929. PMID: 38537991
Artificial intelligence for predictive biomarker discovery in immuno-oncology: a systematic review.
Prelaj A, Miskovic V, Zanitti M, Trovo F, Genova C, Viscardi G, Rebuzzi SE, Mazzeo L, Provenzano L, Kosta S, Favali M, Spagnoletti A, Castelo-Branco L, Dolezal J, Pearson AT, Lo Russo G, Proto C, Ganzinelli M, Giani C, Ambrosini E, Turajlic S, Au L, Koopman M, Delaloge S, Kather JN, de Braud F, Garassino MC, Pentheroudakis G, Spencer C, Pedrocchi ALG
Ann Oncol 2024 Jan;35(1):29-65. Epub 2023 Oct 23 doi: 10.1016/j.annonc.2023.10.125. PMID: 37879443
Increased retinoic acid signaling decreases lung metastasis in salivary adenoid cystic carcinoma by inhibiting the noncanonical Notch1 pathway.
Zhou MJ, Yang JJ, Ma TY, Feng GX, Wang XL, Wang LY, Ge YZ, Gao R, Liu HL, Shan L, Kong L, Chen XH
Exp Mol Med 2023 Mar;55(3):597-611. Epub 2023 Mar 6 doi: 10.1038/s12276-023-00957-7. PMID: 36879115Free PMC Article
Lenvatinib in Management of Solid Tumors.
Hao Z, Wang P
Oncologist 2020 Feb;25(2):e302-e310. Epub 2019 Oct 14 doi: 10.1634/theoncologist.2019-0407. PMID: 32043789Free PMC Article
Extracellular vesicles of carcinoma-associated fibroblasts creates a pre-metastatic niche in the lung through activating fibroblasts.
Kong J, Tian H, Zhang F, Zhang Z, Li J, Liu X, Li X, Liu J, Li X, Jin D, Yang X, Sun B, Guo T, Luo Y, Lu Y, Lin B, Liu T
Mol Cancer 2019 Dec 3;18(1):175. doi: 10.1186/s12943-019-1101-4. PMID: 31796058Free PMC Article

Recent systematic reviews

Artificial intelligence for predictive biomarker discovery in immuno-oncology: a systematic review.
Prelaj A, Miskovic V, Zanitti M, Trovo F, Genova C, Viscardi G, Rebuzzi SE, Mazzeo L, Provenzano L, Kosta S, Favali M, Spagnoletti A, Castelo-Branco L, Dolezal J, Pearson AT, Lo Russo G, Proto C, Ganzinelli M, Giani C, Ambrosini E, Turajlic S, Au L, Koopman M, Delaloge S, Kather JN, de Braud F, Garassino MC, Pentheroudakis G, Spencer C, Pedrocchi ALG
Ann Oncol 2024 Jan;35(1):29-65. Epub 2023 Oct 23 doi: 10.1016/j.annonc.2023.10.125. PMID: 37879443
Clinical features, treatment and outcomes in patients with tracheal adenoid cystic carcinoma: a systematic literature review.
Ran J, Qu G, Chen X, Zhao D
Radiat Oncol 2021 Feb 19;16(1):38. doi: 10.1186/s13014-021-01770-0. PMID: 33608038Free PMC Article
Demography, patterns of care and survival outcomes in patients with malignant tumors of trachea: A systematic review and individual patient data analysis of 733 patients.
Mallick S, Benson R, Giridhar P, Rajan Singh A, Rath GK
Lung Cancer 2019 Jun;132:87-93. Epub 2019 Apr 10 doi: 10.1016/j.lungcan.2019.04.017. PMID: 31097099
Change of Circulating and Tissue-Based miR-20a in Human Cancers and Associated Prognostic Implication: A Systematic Review and Meta-Analysis.
Zhang Q, Wang Q, Sun W, Gao F, Liu L, Cheng L, Li Z
Biomed Res Int 2018;2018:6124927. Epub 2018 Nov 25 doi: 10.1155/2018/6124927. PMID: 30596096Free PMC Article
Systemic therapy in the management of metastatic or locally recurrent adenoid cystic carcinoma of the salivary glands: a systematic review.
Laurie SA, Ho AL, Fury MG, Sherman E, Pfister DG
Lancet Oncol 2011 Aug;12(8):815-24. Epub 2010 Dec 10 doi: 10.1016/S1470-2045(10)70245-X. PMID: 21147032

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