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Pregnancy Complications, Hematologic

MedGen UID:
18614
Concept ID:
C0032964
Disease or Syndrome
Synonyms: Complication, Hematologic Pregnancy; Complication, Hematological Pregnancy; Complications, Hematologic Pregnancy; Complications, Hematological Pregnancy; Hematologic Pregnancy Complication; Hematologic Pregnancy Complications; Hematological Pregnancy Complication; Hematological Pregnancy Complications; Pregnancies, Hematologic Complications; Pregnancy Complication, Hematologic; Pregnancy Complication, Hematological; Pregnancy Complications, Hematological; Pregnancy, Hematologic Complications

Definition

The co-occurrence of pregnancy and a blood disease (HEMATOLOGIC DISEASES) which involves BLOOD CELLS or COAGULATION FACTORS. The hematologic disease may precede or follow FERTILIZATION and it may or may not have a deleterious effect on the pregnant woman or FETUS. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPregnancy Complications, Hematologic

Professional guidelines

PubMed

VARDE KN
J Obstet Gynaecol Br Commonw 1964 Dec;71:919-22. doi: 10.1111/j.1471-0528.1964.tb04380.x. PMID: 14243212
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Recent clinical studies

Etiology

Pishko AM, Levine LD, Cines DB
Blood Rev 2020 Mar;40:100638. Epub 2019 Nov 6 doi: 10.1016/j.blre.2019.100638. PMID: 31757523
Eslick R, McLintock C
Platelets 2020;31(3):300-306. Epub 2019 Jul 11 doi: 10.1080/09537104.2019.1640870. PMID: 31296105
Castaman G, James PD
Eur J Haematol 2019 Aug;103(2):73-79. Epub 2019 May 31 doi: 10.1111/ejh.13250. PMID: 31107984Free PMC Article
Cines DB, Levine LD
Blood 2017 Nov 23;130(21):2271-2277. Epub 2017 Jun 21 doi: 10.1182/blood-2017-05-781971. PMID: 28637667Free PMC Article
Ruiz-Irastorza G, Crowther M, Branch W, Khamashta MA
Lancet 2010 Oct 30;376(9751):1498-509. Epub 2010 Sep 6 doi: 10.1016/S0140-6736(10)60709-X. PMID: 20822807

Diagnosis

Subtil SFC, Mendes JMB, Areia ALFA, Moura JPAS
Rev Bras Ginecol Obstet 2020 Dec;42(12):834-840. Epub 2020 Dec 21 doi: 10.1055/s-0040-1721350. PMID: 33348401Free PMC Article
Pishko AM, Levine LD, Cines DB
Blood Rev 2020 Mar;40:100638. Epub 2019 Nov 6 doi: 10.1016/j.blre.2019.100638. PMID: 31757523
Cines DB, Levine LD
Blood 2017 Nov 23;130(21):2271-2277. Epub 2017 Jun 21 doi: 10.1182/blood-2017-05-781971. PMID: 28637667Free PMC Article
Ruiz-Irastorza G, Crowther M, Branch W, Khamashta MA
Lancet 2010 Oct 30;376(9751):1498-509. Epub 2010 Sep 6 doi: 10.1016/S0140-6736(10)60709-X. PMID: 20822807
Williams MD, Wheby MS
Med Clin North Am 1992 May;76(3):631-47. doi: 10.1016/s0025-7125(16)30344-3. PMID: 1578961

Therapy

Hamulyák EN, Scheres LJ, Marijnen MC, Goddijn M, Middeldorp S
Cochrane Database Syst Rev 2020 May 2;5(5):CD012852. doi: 10.1002/14651858.CD012852.pub2. PMID: 32358837Free PMC Article
Di Renzo GC, Spano F, Giardina I, Brillo E, Clerici G, Roura LC
Womens Health (Lond) 2015 Nov;11(6):891-900. Epub 2015 Oct 16 doi: 10.2217/whe.15.35. PMID: 26472066
Peña-Rosas JP, De-Regil LM, Garcia-Casal MN, Dowswell T
Cochrane Database Syst Rev 2015 Jul 22;2015(7):CD004736. doi: 10.1002/14651858.CD004736.pub5. PMID: 26198451Free PMC Article
Christian P, Mullany LC, Hurley KM, Katz J, Black RE
Semin Perinatol 2015 Aug;39(5):361-72. Epub 2015 Jul 10 doi: 10.1053/j.semperi.2015.06.009. PMID: 26166560
Provan D, Stasi R, Newland AC, Blanchette VS, Bolton-Maggs P, Bussel JB, Chong BH, Cines DB, Gernsheimer TB, Godeau B, Grainger J, Greer I, Hunt BJ, Imbach PA, Lyons G, McMillan R, Rodeghiero F, Sanz MA, Tarantino M, Watson S, Young J, Kuter DJ
Blood 2010 Jan 14;115(2):168-86. Epub 2009 Oct 21 doi: 10.1182/blood-2009-06-225565. PMID: 19846889

Prognosis

Benson AE, Shatzel JJ, Ryan KS, Hedges MA, Martens K, Aslan JE, Lo JO
Eur J Haematol 2022 Dec;109(6):633-642. Epub 2022 Oct 4 doi: 10.1111/ejh.13870. PMID: 36153674Free PMC Article
Smith C, Teng F, Branch E, Chu S, Joseph KS
Obstet Gynecol 2019 Dec;134(6):1234-1244. doi: 10.1097/AOG.0000000000003557. PMID: 31764734Free PMC Article
Christian P, Mullany LC, Hurley KM, Katz J, Black RE
Semin Perinatol 2015 Aug;39(5):361-72. Epub 2015 Jul 10 doi: 10.1053/j.semperi.2015.06.009. PMID: 26166560
James AH
Hematology Am Soc Hematol Educ Program 2009:277-85. doi: 10.1182/asheducation-2009.1.277. PMID: 20008211
Tan JY
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Clinical prediction guides

Fogerty AE, Kuter DJ
Blood 2024 Feb 29;143(9):747-756. doi: 10.1182/blood.2023020726. PMID: 37992219
Smith C, Teng F, Branch E, Chu S, Joseph KS
Obstet Gynecol 2019 Dec;134(6):1234-1244. doi: 10.1097/AOG.0000000000003557. PMID: 31764734Free PMC Article
Castaman G, James PD
Eur J Haematol 2019 Aug;103(2):73-79. Epub 2019 May 31 doi: 10.1111/ejh.13250. PMID: 31107984Free PMC Article
Ruiz-Irastorza G, Crowther M, Branch W, Khamashta MA
Lancet 2010 Oct 30;376(9751):1498-509. Epub 2010 Sep 6 doi: 10.1016/S0140-6736(10)60709-X. PMID: 20822807
Ginsberg JA, Crowther MA, White RH, Ortel TL
Hematology Am Soc Hematol Educ Program 2001:339-57. doi: 10.1182/asheducation-2001.1.339. PMID: 11722992

Recent systematic reviews

Middleton P, Shepherd E, Gomersall JC
Cochrane Database Syst Rev 2021 Mar 29;3(3):CD001689. doi: 10.1002/14651858.CD001689.pub4. PMID: 33779986Free PMC Article
Ugwu NI, Uneke CJ
Niger J Clin Pract 2020 Jul;23(7):889-896. doi: 10.4103/njcp.njcp_197_19. PMID: 32620715
Hamulyák EN, Scheres LJ, Marijnen MC, Goddijn M, Middeldorp S
Cochrane Database Syst Rev 2020 May 2;5(5):CD012852. doi: 10.1002/14651858.CD012852.pub2. PMID: 32358837Free PMC Article
Croles FN, Nasserinejad K, Duvekot JJ, Kruip MJ, Meijer K, Leebeek FW
BMJ 2017 Oct 26;359:j4452. doi: 10.1136/bmj.j4452. PMID: 29074563Free PMC Article
Peña-Rosas JP, De-Regil LM, Garcia-Casal MN, Dowswell T
Cochrane Database Syst Rev 2015 Jul 22;2015(7):CD004736. doi: 10.1002/14651858.CD004736.pub5. PMID: 26198451Free PMC Article

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