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Polyp

MedGen UID:
19397
Concept ID:
C0032584
Anatomical Abnormality
Synonym: Polyps
SNOMED CT: Polyp (441456002); Polyp (41329004)
 
Monarch Initiative: MONDO:0005079

Definition

A usually exophytic mass attached to the underlying tissue by a broad base or a thin stalk. Polyps can be neoplastic or non-neoplastic. Neoplastic polyps usually represent proliferations of the epithelium, and are commonly seen in the gastrointestinal tract. Polyps of the gastrointestinal tract are often called adenomas, are associated with dysplasia, and may eventually transform into carcinomas. Non-neoplastic polyps may be inflammatory, degenerative, or the result of malformations. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPolyp

Professional guidelines

PubMed

Vitale SG, Haimovich S, Laganà AS, Alonso L, Di Spiezio Sardo A, Carugno J; From the Global Community of Hysteroscopy Guidelines Committee
Eur J Obstet Gynecol Reprod Biol 2021 May;260:70-77. Epub 2021 Mar 13 doi: 10.1016/j.ejogrb.2021.03.017. PMID: 33756339
Tanaka S, Saitoh Y, Matsuda T, Igarashi M, Matsumoto T, Iwao Y, Suzuki Y, Nozaki R, Sugai T, Oka S, Itabashi M, Sugihara KI, Tsuruta O, Hirata I, Nishida H, Miwa H, Enomoto N, Shimosegawa T, Koike K
J Gastroenterol 2021 Apr;56(4):323-335. Epub 2021 Mar 12 doi: 10.1007/s00535-021-01776-1. PMID: 33710392Free PMC Article
Marnach ML, Laughlin-Tommaso SK
Mayo Clin Proc 2019 Feb;94(2):326-335. doi: 10.1016/j.mayocp.2018.12.012. PMID: 30711128

Recent clinical studies

Etiology

Gevaert P, Saenz R, Corren J, Han JK, Mullol J, Lee SE, Ow RA, Zhao R, Howard M, Wong K, Islam L, Ligueros-Saylan M, Omachi TA, Bachert C
J Allergy Clin Immunol 2022 Mar;149(3):957-965.e3. Epub 2021 Sep 14 doi: 10.1016/j.jaci.2021.07.045. PMID: 34530020
Karim MM, Ahmed EU, Mozumder S, Zebunnesa M, Azad KA
Mymensingh Med J 2021 Oct;30(4):1086-1092. PMID: 34605481
Hsu CM, Hsu CC, Hsu ZM, Shih FY, Chang ML, Chen TH
Sensors (Basel) 2021 Sep 7;21(18) doi: 10.3390/s21185995. PMID: 34577209Free PMC Article
Desfougères Y, Saiardi A, Azevedo C
Biochem Soc Trans 2020 Feb 28;48(1):95-101. doi: 10.1042/BST20190328. PMID: 32049314Free PMC Article
Ackroyd FW, Hedberg SE
Annu Rev Med 1985;36:619-25. doi: 10.1146/annurev.me.36.020185.003155. PMID: 3994327

Diagnosis

Popović M, Knežević A, Dolinaj Škopelja J, Đolai M
Acta Clin Croat 2022 Aug;61(2):354-358. doi: 10.20471/acc.2022.61.02.23. PMID: 36818922Free PMC Article
Aballa N, Saiad MO
Afr J Paediatr Surg 2021 Jul-Sep;18(3):148-149. doi: 10.4103/ajps.AJPS_88_20. PMID: 34341198Free PMC Article
Olivero F, Foiadelli T, Luzzi S, Marseglia GL, Savasta S
Childs Nerv Syst 2020 Nov;36(11):2635-2640. Epub 2020 Jul 10 doi: 10.1007/s00381-020-04788-z. PMID: 32651596Free PMC Article
Desfougères Y, Saiardi A, Azevedo C
Biochem Soc Trans 2020 Feb 28;48(1):95-101. doi: 10.1042/BST20190328. PMID: 32049314Free PMC Article
Allen JE, Sharma P
Best Pract Res Clin Gastroenterol 2017 Aug;31(4):435-440. Epub 2017 Jul 6 doi: 10.1016/j.bpg.2017.07.001. PMID: 28842053

Therapy

Xu H, Tang RSY, Lam TYT, Zhao G, Lau JYW, Liu Y, Wu Q, Rong L, Xu W, Li X, Wong SH, Cai S, Wang J, Liu G, Ma T, Liang X, Mak JWY, Xu H, Yuan P, Cao T, Li F, Ye Z, Shutian Z, Sung JJY
Clin Gastroenterol Hepatol 2023 Feb;21(2):337-346.e3. Epub 2022 Jul 19 doi: 10.1016/j.cgh.2022.07.006. PMID: 35863686
Chen G, Zhao Y, Xie F, Shi W, Yang Y, Yang A, Wu D
JAMA Netw Open 2021 Nov 1;4(11):e2135576. doi: 10.1001/jamanetworkopen.2021.35576. PMID: 34807255Free PMC Article
Yin J, Ngiam KY, Teo HH
J Med Internet Res 2021 Apr 22;23(4):e25759. doi: 10.2196/25759. PMID: 33885365Free PMC Article
Gevaert P, Omachi TA, Corren J, Mullol J, Han J, Lee SE, Kaufman D, Ligueros-Saylan M, Howard M, Zhu R, Owen R, Wong K, Islam L, Bachert C
J Allergy Clin Immunol 2020 Sep;146(3):595-605. Epub 2020 Jun 7 doi: 10.1016/j.jaci.2020.05.032. PMID: 32524991
Bosteels J, van Wessel S, Weyers S, Broekmans FJ, D'Hooghe TM, Bongers MY, Mol BWJ
Cochrane Database Syst Rev 2018 Dec 5;12(12):CD009461. doi: 10.1002/14651858.CD009461.pub4. PMID: 30521679Free PMC Article

Prognosis

Muller C, Rao VL
Gastrointest Endosc Clin N Am 2022 Apr;32(2):371-384. Epub 2022 Feb 23 doi: 10.1016/j.giec.2021.12.012. PMID: 35361341
Hao Y, Wang Y, Qi M, He X, Zhu Y, Hong J
Gut Liver 2020 Jul 15;14(4):399-411. doi: 10.5009/gnl19097. PMID: 31547641Free PMC Article
He X, Hang D, Wu K, Nayor J, Drew DA, Giovannucci EL, Ogino S, Chan AT, Song M
Gastroenterology 2020 Mar;158(4):852-861.e4. Epub 2019 Jul 11 doi: 10.1053/j.gastro.2019.06.039. PMID: 31302144Free PMC Article
Wang P, Berzin TM, Glissen Brown JR, Bharadwaj S, Becq A, Xiao X, Liu P, Li L, Song Y, Zhang D, Li Y, Xu G, Tu M, Liu X
Gut 2019 Oct;68(10):1813-1819. Epub 2019 Feb 27 doi: 10.1136/gutjnl-2018-317500. PMID: 30814121Free PMC Article
Marnach ML, Laughlin-Tommaso SK
Mayo Clin Proc 2019 Feb;94(2):326-335. doi: 10.1016/j.mayocp.2018.12.012. PMID: 30711128

Clinical prediction guides

Bell PD, Anderson JC, Srivastava A
Am J Surg Pathol 2022 Jan 1;46(1):e64-e70. doi: 10.1097/PAS.0000000000001806. PMID: 34545859
Shaukat A, Kaltenbach T, Dominitz JA, Robertson DJ, Anderson JC, Cruise M, Burke CA, Gupta S, Lieberman D, Syngal S, Rex DK
Gastroenterology 2020 Nov;159(5):1916-1934.e2. Epub 2020 Nov 4 doi: 10.1053/j.gastro.2020.08.050. PMID: 33159840
Tsai SJ, Lin CC, Chang CW, Hung CY, Shieh TY, Wang HY, Shih SC, Chen MJ
World J Gastroenterol 2015 Jan 28;21(4):1091-8. doi: 10.3748/wjg.v21.i4.1091. PMID: 25632181Free PMC Article
Gammon A, Jasperson K, Kohlmann W, Burt RW
Best Pract Res Clin Gastroenterol 2009;23(2):219-31. doi: 10.1016/j.bpg.2009.02.007. PMID: 19414148Free PMC Article
Lai EJ, Calderwood AH, Doros G, Fix OK, Jacobson BC
Gastrointest Endosc 2009 Mar;69(3 Pt 2):620-5. Epub 2009 Jan 10 doi: 10.1016/j.gie.2008.05.057. PMID: 19136102Free PMC Article

Recent systematic reviews

Wu Q, Zhang Y, Kong W, Wang X, Yuan L, Zheng R, Qiu H, Huang X, Yang Q
Int Arch Allergy Immunol 2022;183(3):279-288. Epub 2021 Oct 4 doi: 10.1159/000519228. PMID: 34607329
Oykhman P, Paramo FA, Bousquet J, Kennedy DW, Brignardello-Petersen R, Chu DK
J Allergy Clin Immunol 2022 Apr;149(4):1286-1295. Epub 2021 Sep 17 doi: 10.1016/j.jaci.2021.09.009. PMID: 34543652
Kuntz S, Krieghoff-Henning E, Kather JN, Jutzi T, Höhn J, Kiehl L, Hekler A, Alwers E, von Kalle C, Fröhling S, Utikal JS, Brenner H, Hoffmeister M, Brinker TJ
Eur J Cancer 2021 Sep;155:200-215. Epub 2021 Aug 11 doi: 10.1016/j.ejca.2021.07.012. PMID: 34391053
Yin J, Ngiam KY, Teo HH
J Med Internet Res 2021 Apr 22;23(4):e25759. doi: 10.2196/25759. PMID: 33885365Free PMC Article
Hassan C, Spadaccini M, Iannone A, Maselli R, Jovani M, Chandrasekar VT, Antonelli G, Yu H, Areia M, Dinis-Ribeiro M, Bhandari P, Sharma P, Rex DK, Rösch T, Wallace M, Repici A
Gastrointest Endosc 2021 Jan;93(1):77-85.e6. Epub 2020 Jun 26 doi: 10.1016/j.gie.2020.06.059. PMID: 32598963

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