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Preleukemias

MedGen UID:
19454
Concept ID:
C0033027
Neoplastic Process
Synonym: Preleukemia

Definition

Conditions in which the abnormalities in the peripheral blood or bone marrow represent the early manifestations of acute leukemia, but in which the changes are not of sufficient magnitude or specificity to permit a diagnosis of acute leukemia by the usual clinical criteria. [from MeSH]

Term Hierarchy

Professional guidelines

PubMed

Steinmann GG, Göd B, Rosenkaimer F, Adolf G, Bidlingmaier G, Frühbeis B, Lamche H, Lindner J, Patzelt E, Schmähling C
Clin Investig 1992 Feb;70(2):136-41. doi: 10.1007/BF00227355. PMID: 1600338
Brusamolino E, Papa G, Valagussa P, Mandelli F, Bernasconi C, Marmont A, Bonadonna G, Tura S, Bosi A, Mango G
Hematol Oncol 1987 Apr-Jun;5(2):83-98. doi: 10.1002/hon.2900050203. PMID: 2439431

Recent clinical studies

Etiology

Radivoyevitch T, Jankovic GM, Tiu RV, Saunthararajah Y, Jackson RC, Hlatky LR, Gale RP, Sachs RK
Radiat Environ Biophys 2014 Mar;53(1):55-63. Epub 2013 Dec 13 doi: 10.1007/s00411-013-0507-4. PMID: 24337217Free PMC Article
Shi J, Shao ZH, Liu H, Bai J, Cao YR, He GS, Tu MF, Wang XL, Hao YS, Yang TY, Yang CL
Chin Med J (Engl) 2004 Jul;117(7):963-7. PMID: 15265365
Mele A, Stazi MA, Pulsoni A, Visani G, Monarca B, Castelli G, Rocchi L, Avvisati G, Mandelli F
Haematologica 1995 Sep-Oct;80(5):405-8. PMID: 8566879
Schellong G, Brämswig JH, Hörnig-Franz I
Ann Oncol 1992 Sep;3 Suppl 4:73-6. doi: 10.1093/annonc/3.suppl_4.s73. PMID: 1450084
Nowell PC
Hum Pathol 1981 Jun;12(6):522-30. doi: 10.1016/s0046-8177(81)80066-4. PMID: 7275093

Diagnosis

Radivoyevitch T, Jankovic GM, Tiu RV, Saunthararajah Y, Jackson RC, Hlatky LR, Gale RP, Sachs RK
Radiat Environ Biophys 2014 Mar;53(1):55-63. Epub 2013 Dec 13 doi: 10.1007/s00411-013-0507-4. PMID: 24337217Free PMC Article
Lübbert M, Mirro J Jr, Kitchingman G, McCormick F, Mertelsmann R, Herrmann F, Koeffler HP
Oncogene 1992 Feb;7(2):263-8. PMID: 1549347
Sheppard DM, Richkind KE, Bull M
Cancer Genet Cytogenet 1989 Mar;38(1):49-52. doi: 10.1016/0165-4608(89)90164-7. PMID: 2713814
Nowell PC
Hum Pathol 1981 Jun;12(6):522-30. doi: 10.1016/s0046-8177(81)80066-4. PMID: 7275093

Therapy

Radivoyevitch T, Jankovic GM, Tiu RV, Saunthararajah Y, Jackson RC, Hlatky LR, Gale RP, Sachs RK
Radiat Environ Biophys 2014 Mar;53(1):55-63. Epub 2013 Dec 13 doi: 10.1007/s00411-013-0507-4. PMID: 24337217Free PMC Article
Mele A, Stazi MA, Pulsoni A, Visani G, Monarca B, Castelli G, Rocchi L, Avvisati G, Mandelli F
Haematologica 1995 Sep-Oct;80(5):405-8. PMID: 8566879
Schellong G, Brämswig JH, Hörnig-Franz I
Ann Oncol 1992 Sep;3 Suppl 4:73-6. doi: 10.1093/annonc/3.suppl_4.s73. PMID: 1450084
Henry-Amar M, Pellae-Cosset B, Bayle-Weisgerber C, Hayat M, Cosset JM, Carde P, Tubiana M
Recent Results Cancer Res 1989;117:270-83. doi: 10.1007/978-3-642-83781-4_30. PMID: 2602650
Brusamolino E, Papa G, Valagussa P, Mandelli F, Bernasconi C, Marmont A, Bonadonna G, Tura S, Bosi A, Mango G
Hematol Oncol 1987 Apr-Jun;5(2):83-98. doi: 10.1002/hon.2900050203. PMID: 2439431

Prognosis

Radivoyevitch T, Jankovic GM, Tiu RV, Saunthararajah Y, Jackson RC, Hlatky LR, Gale RP, Sachs RK
Radiat Environ Biophys 2014 Mar;53(1):55-63. Epub 2013 Dec 13 doi: 10.1007/s00411-013-0507-4. PMID: 24337217Free PMC Article
Shi J, Shao ZH, Liu H, Bai J, Cao YR, He GS, Tu MF, Wang XL, Hao YS, Yang TY, Yang CL
Chin Med J (Engl) 2004 Jul;117(7):963-7. PMID: 15265365
Mele A, Stazi MA, Pulsoni A, Visani G, Monarca B, Castelli G, Rocchi L, Avvisati G, Mandelli F
Haematologica 1995 Sep-Oct;80(5):405-8. PMID: 8566879
Schellong G, Brämswig JH, Hörnig-Franz I
Ann Oncol 1992 Sep;3 Suppl 4:73-6. doi: 10.1093/annonc/3.suppl_4.s73. PMID: 1450084
Nowell PC
Hum Pathol 1981 Jun;12(6):522-30. doi: 10.1016/s0046-8177(81)80066-4. PMID: 7275093

Clinical prediction guides

Shi J, Shao ZH, Liu H, Bai J, Cao YR, He GS, Tu MF, Wang XL, Hao YS, Yang TY, Yang CL
Chin Med J (Engl) 2004 Jul;117(7):963-7. PMID: 15265365
Mele A, Stazi MA, Pulsoni A, Visani G, Monarca B, Castelli G, Rocchi L, Avvisati G, Mandelli F
Haematologica 1995 Sep-Oct;80(5):405-8. PMID: 8566879
Schellong G, Brämswig JH, Hörnig-Franz I
Ann Oncol 1992 Sep;3 Suppl 4:73-6. doi: 10.1093/annonc/3.suppl_4.s73. PMID: 1450084
Brusamolino E, Papa G, Valagussa P, Mandelli F, Bernasconi C, Marmont A, Bonadonna G, Tura S, Bosi A, Mango G
Hematol Oncol 1987 Apr-Jun;5(2):83-98. doi: 10.1002/hon.2900050203. PMID: 2439431
Nowell PC
Hum Pathol 1981 Jun;12(6):522-30. doi: 10.1016/s0046-8177(81)80066-4. PMID: 7275093

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