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Male orgasm disorder

MedGen UID:
19560
•Concept ID:
C0033949
•
Mental or Behavioral Dysfunction
Synonyms: Inhibited male orgasm; inhibited male orgasm; male orgasm disorder; Male orgasmic disorder; Male Orgasmic Disorder; male orgasmic disorder
SNOMED CT: Inhibited male orgasm (81903006); Male orgasmic disorder (81903006)
 
Monarch Initiative: MONDO:0003522

Definition

Persistent delay or absence in orgasm not accounted for by a medical reason. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMale orgasm disorder

Professional guidelines

PubMed

Diagnosis and Management of Priapism.
Fantus RJ, Brannigan RE, Davis AM
JAMA 2023 Aug 8;330(6):559-560. doi: 10.1001/jama.2023.13377. PMID: 37471069
Current diagnosis and management of erectile dysfunction.
McMahon CG
Med J Aust 2019 Jun;210(10):469-476. Epub 2019 May 17 doi: 10.5694/mja2.50167. PMID: 31099420
Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society Clinical Practice Guideline.
Hembree WC, Cohen-Kettenis PT, Gooren L, Hannema SE, Meyer WJ, Murad MH, Rosenthal SM, Safer JD, Tangpricha V, T'Sjoen GG
J Clin Endocrinol Metab 2017 Nov 1;102(11):3869-3903. doi: 10.1210/jc.2017-01658. PMID: 28945902

Recent clinical studies

Etiology

Androgen therapy for women after menopause.
Marko KI, Simon JA
Best Pract Res Clin Endocrinol Metab 2021 Dec;35(6):101592. Epub 2021 Oct 12 doi: 10.1016/j.beem.2021.101592. PMID: 34674962
Risks of Testosterone for Postmenopausal Women.
Pinkerton JV, Blackman I, Conner EA, Kaunitz AM
Endocrinol Metab Clin North Am 2021 Mar;50(1):139-150. Epub 2021 Jan 11 doi: 10.1016/j.ecl.2020.10.007. PMID: 33518182
Topiramate-associated sexual dysfunction: A systematic review.
Chen LW, Chen MY, Chen KY, Lin HS, Chien CC, Yin HL
Epilepsy Behav 2017 Aug;73:10-17. Epub 2017 Jun 9 doi: 10.1016/j.yebeh.2017.05.014. PMID: 28605628
Delayed orgasm and anorgasmia.
Jenkins LC, Mulhall JP
Fertil Steril 2015 Nov;104(5):1082-8. Epub 2015 Oct 9 doi: 10.1016/j.fertnstert.2015.09.029. PMID: 26439762Free PMC Article
Introduction: Ejaculatory problems and male infertility.
Sigman M
Fertil Steril 2015 Nov;104(5):1049-50. Epub 2015 Oct 1 doi: 10.1016/j.fertnstert.2015.09.026. PMID: 26432529

Diagnosis

Sexual Performance Anxiety.
Pyke RE
Sex Med Rev 2020 Apr;8(2):183-190. Epub 2019 Aug 22 doi: 10.1016/j.sxmr.2019.07.001. PMID: 31447414
INFERTILITY AND SEXUAL DYSFUNCTIONS: A SYSTEMATIC LITERATURE REVIEW.
Starc A, Trampuš M, Pavan Jukić D, Rotim C, Jukić T, Polona Mivšek A
Acta Clin Croat 2019 Sep;58(3):508-515. doi: 10.20471/acc.2019.58.03.15. PMID: 31969764Free PMC Article
Delayed orgasm and anorgasmia.
Jenkins LC, Mulhall JP
Fertil Steril 2015 Nov;104(5):1082-8. Epub 2015 Oct 9 doi: 10.1016/j.fertnstert.2015.09.029. PMID: 26439762Free PMC Article
Normal male sexual function: emphasis on orgasm and ejaculation.
Alwaal A, Breyer BN, Lue TF
Fertil Steril 2015 Nov;104(5):1051-60. Epub 2015 Sep 16 doi: 10.1016/j.fertnstert.2015.08.033. PMID: 26385403Free PMC Article
A validated measure of no sexual attraction: the Asexuality Identification Scale.
Yule MA, Brotto LA, Gorzalka BB
Psychol Assess 2015 Mar;27(1):148-60. Epub 2014 Nov 10 doi: 10.1037/a0038196. PMID: 25383584

Therapy

Androgen therapy for women after menopause.
Marko KI, Simon JA
Best Pract Res Clin Endocrinol Metab 2021 Dec;35(6):101592. Epub 2021 Oct 12 doi: 10.1016/j.beem.2021.101592. PMID: 34674962
Risks of Testosterone for Postmenopausal Women.
Pinkerton JV, Blackman I, Conner EA, Kaunitz AM
Endocrinol Metab Clin North Am 2021 Mar;50(1):139-150. Epub 2021 Jan 11 doi: 10.1016/j.ecl.2020.10.007. PMID: 33518182
Sexual Performance Anxiety.
Pyke RE
Sex Med Rev 2020 Apr;8(2):183-190. Epub 2019 Aug 22 doi: 10.1016/j.sxmr.2019.07.001. PMID: 31447414
Treatment-emergent sexual dysfunction related to antidepressants: a meta-analysis.
Serretti A, Chiesa A
J Clin Psychopharmacol 2009 Jun;29(3):259-66. doi: 10.1097/JCP.0b013e3181a5233f. PMID: 19440080
Antidepressant-induced sexual dysfunction.
Gregorian RS, Golden KA, Bahce A, Goodman C, Kwong WJ, Khan ZM
Ann Pharmacother 2002 Oct;36(10):1577-89. doi: 10.1345/aph.1A195. PMID: 12243609

Prognosis

Gender incongruence and gender dysphoria in childhood and adolescence-current insights in diagnostics, management, and follow-up.
Claahsen-van der Grinten H, Verhaak C, Steensma T, Middelberg T, Roeffen J, Klink D
Eur J Pediatr 2021 May;180(5):1349-1357. Epub 2020 Dec 18 doi: 10.1007/s00431-020-03906-y. PMID: 33337526Free PMC Article
Delayed orgasm and anorgasmia.
Jenkins LC, Mulhall JP
Fertil Steril 2015 Nov;104(5):1082-8. Epub 2015 Oct 9 doi: 10.1016/j.fertnstert.2015.09.029. PMID: 26439762Free PMC Article
Psychosocial aspects of ejaculatory dysfunction and male reproduction.
Wincze JP
Fertil Steril 2015 Nov;104(5):1089-94. Epub 2015 Aug 19 doi: 10.1016/j.fertnstert.2015.07.1155. PMID: 26297900
Erectile dysfunction.
Burnett AL
J Urol 2006 Mar;175(3 Pt 2):S25-31. doi: 10.1016/S0022-5347(05)00309-5. PMID: 16458737
Sexual dysfunction in the United States: prevalence and predictors.
Laumann EO, Paik A, Rosen RC
JAMA 1999 Feb 10;281(6):537-44. doi: 10.1001/jama.281.6.537. PMID: 10022110

Clinical prediction guides

Sexual Dysfunction in Schizophrenia: A Systematic Review and Meta-Analysis.
Korchia T, Achour V, Faugere M, Albeash A, Yon DK, Boyer L, Fond G
JAMA Psychiatry 2023 Nov 1;80(11):1110-1120. doi: 10.1001/jamapsychiatry.2023.2696. PMID: 37703012Free PMC Article
Topiramate-associated sexual dysfunction: A systematic review.
Chen LW, Chen MY, Chen KY, Lin HS, Chien CC, Yin HL
Epilepsy Behav 2017 Aug;73:10-17. Epub 2017 Jun 9 doi: 10.1016/j.yebeh.2017.05.014. PMID: 28605628
Delayed orgasm and anorgasmia.
Jenkins LC, Mulhall JP
Fertil Steril 2015 Nov;104(5):1082-8. Epub 2015 Oct 9 doi: 10.1016/j.fertnstert.2015.09.029. PMID: 26439762Free PMC Article
A double-blind, randomized, pilot dose-finding study of maca root (L. meyenii) for the management of SSRI-induced sexual dysfunction.
Dording CM, Fisher L, Papakostas G, Farabaugh A, Sonawalla S, Fava M, Mischoulon D
CNS Neurosci Ther 2008 Fall;14(3):182-91. doi: 10.1111/j.1755-5949.2008.00052.x. PMID: 18801111Free PMC Article
Antidepressant-induced sexual dysfunction.
Gregorian RS, Golden KA, Bahce A, Goodman C, Kwong WJ, Khan ZM
Ann Pharmacother 2002 Oct;36(10):1577-89. doi: 10.1345/aph.1A195. PMID: 12243609

Recent systematic reviews

Gender identity disorder (GID) in adolescents and adults with differences of sex development (DSD): A systematic review and meta-analysis.
Babu R, Shah U
J Pediatr Urol 2021 Feb;17(1):39-47. Epub 2020 Nov 12 doi: 10.1016/j.jpurol.2020.11.017. PMID: 33246831
INFERTILITY AND SEXUAL DYSFUNCTIONS: A SYSTEMATIC LITERATURE REVIEW.
Starc A, Trampuš M, Pavan Jukić D, Rotim C, Jukić T, Polona Mivšek A
Acta Clin Croat 2019 Sep;58(3):508-515. doi: 10.20471/acc.2019.58.03.15. PMID: 31969764Free PMC Article
Adverse Sexual Effects of Treatment with Finasteride or Dutasteride for Male Androgenetic Alopecia: A Systematic Review and Meta-analysis.
Lee S, Lee YB, Choe SJ, Lee WS
Acta Derm Venereol 2019 Jan 1;99(1):12-17. doi: 10.2340/00015555-3035. PMID: 30206635
Prostate cancer screening with prostate-specific antigen (PSA) test: a systematic review and meta-analysis.
Ilic D, Djulbegovic M, Jung JH, Hwang EC, Zhou Q, Cleves A, Agoritsas T, Dahm P
BMJ 2018 Sep 5;362:k3519. doi: 10.1136/bmj.k3519. PMID: 30185521Free PMC Article
Erectile Dysfunction: AUA Guideline.
Burnett AL, Nehra A, Breau RH, Culkin DJ, Faraday MM, Hakim LS, Heidelbaugh J, Khera M, McVary KT, Miner MM, Nelson CJ, Sadeghi-Nejad H, Seftel AD, Shindel AW
J Urol 2018 Sep;200(3):633-641. Epub 2018 May 7 doi: 10.1016/j.juro.2018.05.004. PMID: 29746858

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