U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Benign neoplasm of neck

MedGen UID:
195775
Concept ID:
C0684815
Neoplastic Process
Synonyms: Benign Neck Neoplasm; benign neck neoplasm; Benign Neck Tumor; benign neck tumor; benign neck tumour; Benign Neoplasm of Neck; benign neoplasm of neck; Benign Neoplasm of the Neck; benign neoplasm of the neck; Benign tumor of neck; Benign Tumor of Neck; benign tumor of neck; Benign Tumor of the Neck; benign tumor of the neck; benign tumour of neck; benign tumour of the neck; neck benign neoplasm
SNOMED CT: Benign tumor of neck (92246000); Benign neoplasm of neck (92246000)
 
Monarch Initiative: MONDO:0021455

Definition

A neoplasm that arises from the neck region and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign neoplasm of neck

Professional guidelines

PubMed

Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, Soares P, Solymosi T, Papini E
Eur Thyroid J 2023 Oct 1;12(5) Epub 2023 Aug 14 doi: 10.1530/ETJ-23-0067. PMID: 37358008Free PMC Article
Owen JL, Kibbi N, Worley B, Kelm RC, Wang JV, Barker CA, Behshad R, Bichakjian CK, Bolotin D, Bordeaux JS, Bradshaw SH, Cartee TV, Chandra S, Cho NL, Choi JN, Council ML, Demirci H, Eisen DB, Esmaeli B, Golda N, Huang CC, Ibrahim SF, Jiang SB, Kim J, Kuzel TM, Lai SY, Lawrence N, Lee EH, Leitenberger JJ, Maher IA, Mann MW, Minkis K, Mittal BB, Nehal KS, Neuhaus IM, Ozog DM, Petersen B, Rotemberg V, Samant S, Samie FH, Servaes S, Shields CL, Shin TM, Sobanko JF, Somani AK, Stebbins WG, Thomas JR, Thomas VD, Tse DT, Waldman AH, Wong MK, Xu YG, Yu SS, Zeitouni NC, Ramsay T, Reynolds KA, Poon E, Alam M
Lancet Oncol 2019 Dec;20(12):e699-e714. doi: 10.1016/S1470-2045(19)30673-4. PMID: 31797796
Grégoire V, Ang K, Budach W, Grau C, Hamoir M, Langendijk JA, Lee A, Le QT, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Lengele B
Radiother Oncol 2014 Jan;110(1):172-81. Epub 2013 Oct 31 doi: 10.1016/j.radonc.2013.10.010. PMID: 24183870

Recent clinical studies

Etiology

Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, Soares P, Solymosi T, Papini E
Eur Thyroid J 2023 Oct 1;12(5) Epub 2023 Aug 14 doi: 10.1530/ETJ-23-0067. PMID: 37358008Free PMC Article
Pupić-Bakrač J, Pupić-Bakrač A, Novaković J, Skitarelić N
J Craniofac Surg 2021 Jun 1;32(4):1417-1420. doi: 10.1097/SCS.0000000000007122. PMID: 33170821
Quintanilla-Dieck L, Penn EB Jr
Clin Perinatol 2018 Dec;45(4):769-785. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.012. PMID: 30396417
Brouwer CL, Steenbakkers RJ, Bourhis J, Budach W, Grau C, Grégoire V, van Herk M, Lee A, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Rosenthal DI, Sijtsema NM, Langendijk JA
Radiother Oncol 2015 Oct;117(1):83-90. Epub 2015 Aug 13 doi: 10.1016/j.radonc.2015.07.041. PMID: 26277855
Grégoire V, Ang K, Budach W, Grau C, Hamoir M, Langendijk JA, Lee A, Le QT, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Lengele B
Radiother Oncol 2014 Jan;110(1):172-81. Epub 2013 Oct 31 doi: 10.1016/j.radonc.2013.10.010. PMID: 24183870

Diagnosis

Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, Soares P, Solymosi T, Papini E
Eur Thyroid J 2023 Oct 1;12(5) Epub 2023 Aug 14 doi: 10.1530/ETJ-23-0067. PMID: 37358008Free PMC Article
Kobayashi K, Hanai N, Yoshimoto S, Saito Y, Homma A
Jpn J Clin Oncol 2023 Aug 30;53(9):743-756. doi: 10.1093/jjco/hyad048. PMID: 37309253Free PMC Article
Chorath K, Rajasekaran K
Med Clin North Am 2021 Sep;105(5):827-837. Epub 2021 Jul 12 doi: 10.1016/j.mcna.2021.05.005. PMID: 34391536
Pupić-Bakrač J, Pupić-Bakrač A, Novaković J, Skitarelić N
J Craniofac Surg 2021 Jun 1;32(4):1417-1420. doi: 10.1097/SCS.0000000000007122. PMID: 33170821
Quintanilla-Dieck L, Penn EB Jr
Clin Perinatol 2018 Dec;45(4):769-785. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.012. PMID: 30396417

Therapy

Ferris RL, Harrington K, Schoenfeld JD, Tahara M, Esdar C, Salmio S, Schroeder A, Bourhis J
Cancer Treat Rev 2023 Feb;113:102492. Epub 2022 Nov 30 doi: 10.1016/j.ctrv.2022.102492. PMID: 36640618
Leboulleux S, Bournaud C, Chougnet CN, Zerdoud S, Al Ghuzlan A, Catargi B, Do Cao C, Kelly A, Barge ML, Lacroix L, Dygai I, Vera P, Rusu D, Schneegans O, Benisvy D, Klein M, Roux J, Eberle MC, Bastie D, Nascimento C, Giraudet AL, Le Moullec N, Bardet S, Drui D, Roudaut N, Godbert Y, Morel O, Drutel A, Lamartina L, Schvartz C, Velayoudom FL, Schlumberger MJ, Leenhardt L, Borget I
N Engl J Med 2022 Mar 10;386(10):923-932. doi: 10.1056/NEJMoa2111953. PMID: 35263518
Harris P, Durand R, Schmittbuhl M, Kabir R
J Stomatol Oral Maxillofac Surg 2022 Jun;123(3):e20-e27. Epub 2021 Jun 23 doi: 10.1016/j.jormas.2021.06.005. PMID: 34171527
Mijiti A, Kuerbantayi N, Zhang ZQ, Su MY, Zhang XH, Huojia M
Head Neck 2020 Aug;42(8):2165-2180. Epub 2020 Mar 4 doi: 10.1002/hed.26136. PMID: 32129547
Brouwer CL, Steenbakkers RJ, Bourhis J, Budach W, Grau C, Grégoire V, van Herk M, Lee A, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Rosenthal DI, Sijtsema NM, Langendijk JA
Radiother Oncol 2015 Oct;117(1):83-90. Epub 2015 Aug 13 doi: 10.1016/j.radonc.2015.07.041. PMID: 26277855

Prognosis

Wreesmann VB, Oomen KP, Brennan PA
J Oral Pathol Med 2022 Nov;51(10):904-910. Epub 2022 Sep 20 doi: 10.1111/jop.13354. PMID: 36066314
Wong BLK, Hogan C
Braz J Otorhinolaryngol 2022 Nov-Dec;88 Suppl 4(Suppl 4):S177-S187. Epub 2022 May 20 doi: 10.1016/j.bjorl.2022.04.002. PMID: 35659712Free PMC Article
Leboulleux S, Bournaud C, Chougnet CN, Zerdoud S, Al Ghuzlan A, Catargi B, Do Cao C, Kelly A, Barge ML, Lacroix L, Dygai I, Vera P, Rusu D, Schneegans O, Benisvy D, Klein M, Roux J, Eberle MC, Bastie D, Nascimento C, Giraudet AL, Le Moullec N, Bardet S, Drui D, Roudaut N, Godbert Y, Morel O, Drutel A, Lamartina L, Schvartz C, Velayoudom FL, Schlumberger MJ, Leenhardt L, Borget I
N Engl J Med 2022 Mar 10;386(10):923-932. doi: 10.1056/NEJMoa2111953. PMID: 35263518
Zanoni DK, Montero PH, Migliacci JC, Shah JP, Wong RJ, Ganly I, Patel SG
Oral Oncol 2019 Mar;90:115-121. Epub 2019 Feb 15 doi: 10.1016/j.oraloncology.2019.02.001. PMID: 30846169Free PMC Article
Quintanilla-Dieck L, Penn EB Jr
Clin Perinatol 2018 Dec;45(4):769-785. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.012. PMID: 30396417

Clinical prediction guides

Rades D, Delikanli C, Yu NY, Janssen S
Anticancer Res 2023 Sep;43(9):4149-4153. doi: 10.21873/anticanres.16605. PMID: 37648327
Wishart LR, Ward EC, Galloway G
Curr Opin Otolaryngol Head Neck Surg 2023 Dec 1;31(6):368-373. Epub 2023 Aug 4 doi: 10.1097/MOO.0000000000000918. PMID: 37548514
Zidar N, Gale N
Head Neck Pathol 2022 Mar;16(1):31-39. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01405-6. PMID: 35312977Free PMC Article
Strohl MP, El-Sayed IH
Curr Oncol Rep 2019 Nov 14;21(11):103. doi: 10.1007/s11912-019-0853-8. PMID: 31728649
Brouwer CL, Steenbakkers RJ, Bourhis J, Budach W, Grau C, Grégoire V, van Herk M, Lee A, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Rosenthal DI, Sijtsema NM, Langendijk JA
Radiother Oncol 2015 Oct;117(1):83-90. Epub 2015 Aug 13 doi: 10.1016/j.radonc.2015.07.041. PMID: 26277855

Recent systematic reviews

Houpe JE, Seger EW, Neill BC, Kang BY, Hocker TLH, Alam M, Tolkachjov SN
Cutis 2023 May;111(5):247-251. doi: 10.12788/cutis.0767. PMID: 37406332
Fadhil M, Singh R, Havas T, Jacobson I
Head Neck 2022 Oct;44(10):2301-2315. Epub 2022 Jul 11 doi: 10.1002/hed.27136. PMID: 35818729
Vered M, Wright JM
Head Neck Pathol 2022 Mar;16(1):63-75. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01404-7. PMID: 35312978Free PMC Article
Coca-Pelaz A, Mäkitie AA, Strojan P, Corry J, Eisbruch A, Beitler JJ, Nuyts S, Smee R, Langendijk JA, Mendenhall WM, Piazza C, Rinaldo A, Ferlito A
Adv Ther 2021 Jan;38(1):90-108. Epub 2020 Nov 13 doi: 10.1007/s12325-020-01556-y. PMID: 33184778Free PMC Article
Bye A, Sandmael JA, Stene GB, Thorsen L, Balstad TR, Solheim TS, Pripp AH, Oldervoll LM
Nutrients 2020 Oct 22;12(11) doi: 10.3390/nu12113233. PMID: 33105699Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...