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Oculomotor nerve cancer

MedGen UID:
195786
•Concept ID:
C0686417
•
Neoplastic Process
Synonyms: cancer of oculomotor nerve; IIIrd Cranial Nerve Neoplasm, Malignant; IIIrd cranial nerve neoplasm, malignant; malignant neoplasm of oculomotor nerve; Malignant Oculomotor Nerve Neoplasm; malignant oculomotor nerve neoplasm; malignant oculomotor nerve tumor; malignant oculomotor nerve tumour; oculomotor nerve cancer; Oculomotor Nerve Neoplasm, Malignant; oculomotor nerve neoplasm, malignant; Primary malignant neoplasm of oculomotor nerve; primary malignant neoplasm of oculomotor nerve
SNOMED CT: Primary malignant neoplasm of oculomotor nerve (93929003)
 
Monarch Initiative: MONDO:0002434

Definition

A primary or metastatic malignant neoplasm involving the oculomotor nerve. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOculomotor nerve cancer

Professional guidelines

PubMed

The Oculomotor Cistern and Its Role in the Management of Pituitary Lesions: An Anatomical, Radiographic, and Clinical Scoping Review.
Serioli S, Buffoli B, Maroldi R, Mattogno P, Gaudino S, Lauretti L, Rezzani R, Olivi A, Fontanella MM, Rigante M, Doglietto F
World Neurosurg 2023 Apr;172:12-19. Epub 2023 Jan 16 doi: 10.1016/j.wneu.2023.01.048. PMID: 36657712
The spectrum and differential diagnosis of acquired ocular motor nerve palsies: a clinical study of 502 patients.
Hörner R, Kassubek J, Dreyhaupt J, Ludolph AC
J Neurol 2022 Apr;269(4):2140-2148. Epub 2021 Sep 19 doi: 10.1007/s00415-021-10761-w. PMID: 34537871Free PMC Article
Intra-arterial chemotherapy for retinoblastoma treatment in Chile: Experience and results 2013-2020.
Oporto JI, Zúñiga P, Ossandón D, Zanolli M, Pérez V, López JP, Stetcher X, Rodríguez A, Puentes Á, Rustom S, Lobos J
Arch Soc Esp Oftalmol (Engl Ed) 2021 Jun;96(6):288-292. Epub 2021 Feb 27 doi: 10.1016/j.oftale.2020.10.003. PMID: 34092282

Recent clinical studies

Etiology

Parasellar Meningiomas.
Graillon T, Regis J, Barlier A, Brue T, Dufour H, Buchfelder M
Neuroendocrinology 2020;110(9-10):780-796. Epub 2020 Jun 3 doi: 10.1159/000509090. PMID: 32492684
Posterior communicating aneurysm with oculomotor nerve palsy: Predictors of nerve recovery.
Zhong W, Zhang J, Shen J, Zhang P, Wang D, Su W, Wang Y
J Clin Neurosci 2019 Jan;59:62-67. Epub 2018 Nov 16 doi: 10.1016/j.jocn.2018.11.006. PMID: 30455133
Effects of Brain Tumors on Vision in Children.
Peragallo JH
Int Ophthalmol Clin 2018 Fall;58(4):83-95. doi: 10.1097/IIO.0000000000000237. PMID: 30239365Free PMC Article
Isolated third, fourth, and sixth cranial nerve palsies from presumed microvascular versus other causes: a prospective study.
Tamhankar MA, Biousse V, Ying GS, Prasad S, Subramanian PS, Lee MS, Eggenberger E, Moss HE, Pineles S, Bennett J, Osborne B, Volpe NJ, Liu GT, Bruce BB, Newman NJ, Galetta SL, Balcer LJ
Ophthalmology 2013 Nov;120(11):2264-9. Epub 2013 Jun 6 doi: 10.1016/j.ophtha.2013.04.009. PMID: 23747163Free PMC Article
Eye movement disorders.
Liu GT, Volpe NJ, Galetta SL
Curr Opin Ophthalmol 1995 Dec;6(6):27-33. doi: 10.1097/00055735-199512000-00005. PMID: 10160415

Diagnosis

Oculomotor nerve schwannoma: case series and literature review.
Douglas VP, Flores C, Douglas KA, Strominger MB, Kasper E, Torun N
Surv Ophthalmol 2022 Jul-Aug;67(4):1160-1174. Epub 2021 Nov 21 doi: 10.1016/j.survophthal.2021.11.008. PMID: 34813853
Parasellar Meningiomas.
Graillon T, Regis J, Barlier A, Brue T, Dufour H, Buchfelder M
Neuroendocrinology 2020;110(9-10):780-796. Epub 2020 Jun 3 doi: 10.1159/000509090. PMID: 32492684
Ocular Myasthenia.
Al-Haidar M, Benatar M, Kaminski HJ
Neurol Clin 2018 May;36(2):241-251. doi: 10.1016/j.ncl.2018.01.003. PMID: 29655447
Isolated third, fourth, and sixth cranial nerve palsies from presumed microvascular versus other causes: a prospective study.
Tamhankar MA, Biousse V, Ying GS, Prasad S, Subramanian PS, Lee MS, Eggenberger E, Moss HE, Pineles S, Bennett J, Osborne B, Volpe NJ, Liu GT, Bruce BB, Newman NJ, Galetta SL, Balcer LJ
Ophthalmology 2013 Nov;120(11):2264-9. Epub 2013 Jun 6 doi: 10.1016/j.ophtha.2013.04.009. PMID: 23747163Free PMC Article
Ocular myasthenia gravis.
Vaphiades MS, Bhatti MT, Lesser RL
Curr Opin Ophthalmol 2012 Nov;23(6):537-42. doi: 10.1097/ICU.0b013e328358b94a. PMID: 23047171

Therapy

Postoperative Third Nerve Palsy after Endoscopic Endonasal Transsphenoidal Surgery for Pituitary Adenoma: Elucidating its Mechanism.
Villamil F, Caffaratti G, Ruella ME, M Giovannini SJ, Cervio A
Neurol India 2023 May-Jun;71(3):522-526. doi: 10.4103/0028-3886.378673. PMID: 37322750
Posterior communicating aneurysm with oculomotor nerve palsy: Predictors of nerve recovery.
Zhong W, Zhang J, Shen J, Zhang P, Wang D, Su W, Wang Y
J Clin Neurosci 2019 Jan;59:62-67. Epub 2018 Nov 16 doi: 10.1016/j.jocn.2018.11.006. PMID: 30455133
Radiosurgery in trochlear and abducens nerve schwannomas: case series and systematic review.
Peciu-Florianu I, Tuleasca C, Comps JN, Schiappacasse L, Zeverino M, Daniel RT, Levivier M
Acta Neurochir (Wien) 2017 Dec;159(12):2409-2418. Epub 2017 Oct 11 doi: 10.1007/s00701-017-3348-0. PMID: 29022157
Stereotactic radiosurgery for acromegaly.
Lee CC, Vance ML, Xu Z, Yen CP, Schlesinger D, Dodson B, Sheehan J
J Clin Endocrinol Metab 2014 Apr;99(4):1273-81. Epub 2014 Jan 28 doi: 10.1210/jc.2013-3743. PMID: 24471574
Ocular neuromyotonia.
Ezra E, Spalton D, Sanders MD, Graham EM, Plant GT
Br J Ophthalmol 1996 Apr;80(4):350-5. doi: 10.1136/bjo.80.4.350. PMID: 8703889Free PMC Article

Prognosis

Intramuscular Nerves of the Inferior Rectus Muscle: Distribution and Characteristics.
Shin HJ, Lee SH, Ha TJ, Song WC, Lee AG, Koh KS
Curr Eye Res 2020 Dec;45(12):1598-1603. Epub 2020 Jun 18 doi: 10.1080/02713683.2020.1776333. PMID: 32478585
The aetiologies of unilateral oculomotor nerve palsy: a clinical analysis on 121 patients.
Chen H, Wang X, Yao S, Raza HK, Jing J, Cui G, Hua F
Somatosens Mot Res 2019 Jun;36(2):102-108. Epub 2019 Apr 30 doi: 10.1080/08990220.2019.1609438. PMID: 31035834
Posterior communicating aneurysm with oculomotor nerve palsy: Predictors of nerve recovery.
Zhong W, Zhang J, Shen J, Zhang P, Wang D, Su W, Wang Y
J Clin Neurosci 2019 Jan;59:62-67. Epub 2018 Nov 16 doi: 10.1016/j.jocn.2018.11.006. PMID: 30455133
Neuro-ophthalmologic exploration in non-functioning pituitary adenoma.
Abouaf L, Vighetto A, Lebas M
Ann Endocrinol (Paris) 2015 Jul;76(3):210-9. Epub 2015 Jun 10 doi: 10.1016/j.ando.2015.04.006. PMID: 26070465
Ocular myasthenia: a protean disorder.
Weinberg DA, Lesser RL, Vollmer TL
Surv Ophthalmol 1994 Nov-Dec;39(3):169-210. doi: 10.1016/0039-6257(94)90194-5. PMID: 7878520

Clinical prediction guides

Pituitary adenoma with oculomotor cistern extension: membranous anatomy and clinical application.
Wu X, Liang L, Wu BW, Xie SH, Wu J, Wan XC, Din H, Zhan J, Xiao LM, Tang B, Hong T
Acta Neurochir (Wien) 2023 Oct;165(10):2985-2993. Epub 2023 Sep 6 doi: 10.1007/s00701-023-05784-3. PMID: 37672094
Optic nerve motion and gaze direction: Their impact on intraorbital tumor radiotherapy.
Mesny E, Jacob J, Culot F, Calugaru V, Jenny C, Fonti B, Bourdais R, Courtault-Deslandes F, Boulle G, Meillan N, Simon JM, Maingon P, Feuvret L
Cancer Radiother 2022 Sep;26(5):678-683. Epub 2022 Feb 25 doi: 10.1016/j.canrad.2021.12.003. PMID: 35227595
Parasellar Meningiomas.
Graillon T, Regis J, Barlier A, Brue T, Dufour H, Buchfelder M
Neuroendocrinology 2020;110(9-10):780-796. Epub 2020 Jun 3 doi: 10.1159/000509090. PMID: 32492684
Posterior communicating aneurysm with oculomotor nerve palsy: Predictors of nerve recovery.
Zhong W, Zhang J, Shen J, Zhang P, Wang D, Su W, Wang Y
J Clin Neurosci 2019 Jan;59:62-67. Epub 2018 Nov 16 doi: 10.1016/j.jocn.2018.11.006. PMID: 30455133
Isolated third, fourth, and sixth cranial nerve palsies from presumed microvascular versus other causes: a prospective study.
Tamhankar MA, Biousse V, Ying GS, Prasad S, Subramanian PS, Lee MS, Eggenberger E, Moss HE, Pineles S, Bennett J, Osborne B, Volpe NJ, Liu GT, Bruce BB, Newman NJ, Galetta SL, Balcer LJ
Ophthalmology 2013 Nov;120(11):2264-9. Epub 2013 Jun 6 doi: 10.1016/j.ophtha.2013.04.009. PMID: 23747163Free PMC Article

Recent systematic reviews

Isolated Third Cranial Nerve Palsy in Pituitary Apoplexy: Case Report and Systematic Review.
Rosso M, Ramaswamy S, Sucharew H, Vagal A, Anziska Y, Levine SR
J Stroke Cerebrovasc Dis 2021 Sep;30(9):105969. Epub 2021 Jul 22 doi: 10.1016/j.jstrokecerebrovasdis.2021.105969. PMID: 34303962
Cranial Nerve Disorders Associated With Immune Checkpoint Inhibitors.
Vogrig A, Muñiz-Castrillo S, Joubert B, Picard G, Rogemond V, Skowron F, Egri M, Desestret V, Tilikete C, Psimaras D, Ducray F, Honnorat J
Neurology 2021 Feb 9;96(6):e866-e875. Epub 2020 Dec 14 doi: 10.1212/WNL.0000000000011340. PMID: 33318162
Tumor control and trigeminal dysfunction improvement after stereotactic radiosurgery for trigeminal schwannomas: a systematic review and meta-analysis.
Peciu-Florianu I, Régis J, Levivier M, Dedeciusova M, Reyns N, Tuleasca C
Neurosurg Rev 2021 Oct;44(5):2391-2403. Epub 2020 Nov 13 doi: 10.1007/s10143-020-01433-w. PMID: 33185756Free PMC Article
Clinical spectrum and diagnostic pitfalls of neurologic syndromes with Ri antibodies.
Simard C, Vogrig A, Joubert B, Muñiz-Castrillo S, Picard G, Rogemond V, Ducray F, Berzero G, Psimaras D, Antoine JC, Desestret V, Honnorat J
Neurol Neuroimmunol Neuroinflamm 2020 May;7(3) Epub 2020 Mar 13 doi: 10.1212/NXI.0000000000000699. PMID: 32170042Free PMC Article
Radiosurgery in trochlear and abducens nerve schwannomas: case series and systematic review.
Peciu-Florianu I, Tuleasca C, Comps JN, Schiappacasse L, Zeverino M, Daniel RT, Levivier M
Acta Neurochir (Wien) 2017 Dec;159(12):2409-2418. Epub 2017 Oct 11 doi: 10.1007/s00701-017-3348-0. PMID: 29022157

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