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Metastatic Malignant Neoplasm in the Parathyroid Glands

MedGen UID:
195788
Concept ID:
C0686507
Neoplastic Process
Synonyms: Metastasis to the Parathyroid Gland; Metastatic malignant neoplasm of parathyroid gland; Metastatic malignant neoplasm to parathyroid gland; Metastatic Malignant Neoplasm to the Parathyroid Glands; Metastatic Neoplasm to the Parathyroid; Metastatic Neoplasm to the Parathyroid Gland; Metastatic Tumor to the Parathyroid; Metastatic Tumor to the Parathyroid Gland; Secondary malignant neoplasm of parathyroid gland
SNOMED CT: Secondary malignant neoplasm of parathyroid gland (94467003); Metastatic malignant neoplasm to parathyroid gland (94467003); Metastatic malignant neoplasm of parathyroid gland (94467003)

Definition

A malignant neoplasm either directly extending to the parathyroid glands from adjacent anatomic structures, or spreading to the parathyroid glands from distant anatomic sites, most frequently breast, lung, kidney, soft tissues, and skin. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Malignant Neoplasm in the Parathyroid Glands

Professional guidelines

PubMed

Expert Panel on Neurological Imaging, Zander D, Bunch PM, Policeni B, Juliano AF, Carneiro-Pla D, Dubey P, Gule-Monroe MK, Hagiwara M, Hoang JK, Jain V, Kim LT, Moonis G, Parsons MS, Rath TJ, Solórzano CC, Subramaniam RM, Taheri MR, DuChene Thoma K, Trout AT, Zafereo ME Jr, Corey AS
J Am Coll Radiol 2021 Nov;18(11S):S406-S422. doi: 10.1016/j.jacr.2021.08.013. PMID: 34794597
van Leeuwaarde RS, de Laat JM, Pieterman CRC, Dreijerink K, Vriens MR, Valk GD
Endocr Relat Cancer 2017 Oct;24(10):T179-T193. Epub 2017 Aug 2 doi: 10.1530/ERC-17-0225. PMID: 28768698
Gaztambide S, Vazquez F, Castaño L
Minerva Endocrinol 2013 Mar;38(1):17-28. PMID: 23435440

Recent clinical studies

Etiology

Hu X, Saunders N, Safley S, Smith MR, Liang Y, Tran V, Sharma J, Jones DP, Weber CJ
Surgery 2021 Jan;169(1):102-108. Epub 2020 Aug 5 doi: 10.1016/j.surg.2020.06.010. PMID: 32771296Free PMC Article
van Leeuwaarde RS, de Laat JM, Pieterman CRC, Dreijerink K, Vriens MR, Valk GD
Endocr Relat Cancer 2017 Oct;24(10):T179-T193. Epub 2017 Aug 2 doi: 10.1530/ERC-17-0225. PMID: 28768698
Duan K, Gomez Hernandez K, Mete O
J Clin Pathol 2015 Oct;68(10):771-87. Epub 2015 Jul 10 doi: 10.1136/jclinpath-2015-203186. PMID: 26163537
Shifrin A, LiVolsi V, Shifrin-Douglas S, Zheng M, Erler B, Matulewicz T, Davis J
J Clin Endocrinol Metab 2015 Mar;100(3):E478-81. Epub 2014 Dec 9 doi: 10.1210/jc.2014-2760. PMID: 25490272
Senchenkov A, Staren ED
Surg Clin North Am 2004 Aug;84(4):973-1000, v. doi: 10.1016/j.suc.2004.04.007. PMID: 15261750

Diagnosis

Lalonde MN, Correia RD, Syktiotis GP, Schaefer N, Matter M, Prior JO
Semin Nucl Med 2023 Jul;53(4):490-502. Epub 2023 Mar 14 doi: 10.1053/j.semnuclmed.2023.02.004. PMID: 36922339
Gokozan HN, Scognamiglio T
Adv Anat Pathol 2023 Jan 1;30(1):24-33. Epub 2022 Nov 1 doi: 10.1097/PAP.0000000000000379. PMID: 36315270
Erickson LA, Mete O, Juhlin CC, Perren A, Gill AJ
Endocr Pathol 2022 Mar;33(1):64-89. Epub 2022 Feb 17 doi: 10.1007/s12022-022-09709-1. PMID: 35175514
Angelousi A, Alexandraki KI, Kyriakopoulos G, Tsoli M, Thomas D, Kaltsas G, Grossman A
Endocr Relat Cancer 2020 Jan;27(1):R1-R20. doi: 10.1530/ERC-19-0263. PMID: 31645015
Dudney WC, Bodenner D, Stack BC Jr
Otolaryngol Clin North Am 2010 Apr;43(2):441-53, xi. doi: 10.1016/j.otc.2010.01.011. PMID: 20510726

Therapy

Olejarz M, Szczepanek-Parulska E, Ruchala M
Front Endocrinol (Lausanne) 2024;15:1354098. Epub 2024 Apr 2 doi: 10.3389/fendo.2024.1354098. PMID: 38628593Free PMC Article
Whitman J, Allen IE, Bergsland EK, Suh I, Hope TA
J Nucl Med 2021 Sep 1;62(9):1285-1291. Epub 2021 Jan 15 doi: 10.2967/jnumed.120.257303. PMID: 33452040Free PMC Article
Minezaki M, Takashi Y, Ochi K, Mitsuoka R, Yamao Y, Kudo T, Kawanami D, Kobayashi K, Abe I
J Bone Miner Metab 2021 Jul;39(4):583-588. Epub 2021 Jan 6 doi: 10.1007/s00774-020-01190-2. PMID: 33409573
Hu X, Saunders N, Safley S, Smith MR, Liang Y, Tran V, Sharma J, Jones DP, Weber CJ
Surgery 2021 Jan;169(1):102-108. Epub 2020 Aug 5 doi: 10.1016/j.surg.2020.06.010. PMID: 32771296Free PMC Article
Gazelle GS, Goldberg SN, Solbiati L, Livraghi T
Radiology 2000 Dec;217(3):633-46. doi: 10.1148/radiology.217.3.r00dc26633. PMID: 11110923

Prognosis

Marini F, Giusti F, Palmini G, Aurilia C, Donati S, Brandi ML
Endocrine 2023 Sep;81(3):409-418. Epub 2023 May 9 doi: 10.1007/s12020-023-03376-w. PMID: 37160841
Gokozan HN, Scognamiglio T
Adv Anat Pathol 2023 Jan 1;30(1):24-33. Epub 2022 Nov 1 doi: 10.1097/PAP.0000000000000379. PMID: 36315270
Angelousi A, Alexandraki KI, Kyriakopoulos G, Tsoli M, Thomas D, Kaltsas G, Grossman A
Endocr Relat Cancer 2020 Jan;27(1):R1-R20. doi: 10.1530/ERC-19-0263. PMID: 31645015
Duan K, Gomez Hernandez K, Mete O
J Clin Pathol 2015 Oct;68(10):771-87. Epub 2015 Jul 10 doi: 10.1136/jclinpath-2015-203186. PMID: 26163537
Shifrin A, LiVolsi V, Shifrin-Douglas S, Zheng M, Erler B, Matulewicz T, Davis J
J Clin Endocrinol Metab 2015 Mar;100(3):E478-81. Epub 2014 Dec 9 doi: 10.1210/jc.2014-2760. PMID: 25490272

Clinical prediction guides

Halwani C, Turki S, Akkari K
Tunis Med 2020 Oct;98(10):720-725. PMID: 33479944
Duan K, Gomez Hernandez K, Mete O
J Clin Pathol 2015 Oct;68(10):771-87. Epub 2015 Jul 10 doi: 10.1136/jclinpath-2015-203186. PMID: 26163537
Senchenkov A, Staren ED
Surg Clin North Am 2004 Aug;84(4):973-1000, v. doi: 10.1016/j.suc.2004.04.007. PMID: 15261750
Davey DD, Glant MD, Berger EK
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Davies DR, Dent CE, Watson L
Br Med J 1968 Aug 17;3(5615):395-9. doi: 10.1136/bmj.3.5615.395. PMID: 5691200Free PMC Article

Recent systematic reviews

Zhang RJ, Chen YL, Deng X, Yang H
Am Surg 2023 Jun;89(6):2227-2236. Epub 2022 Apr 6 doi: 10.1177/00031348221086780. PMID: 35387525
Spartalis E, Giannakodimos A, Athanasiadis DI, Chrysikos D, Paschou SA, Schizas D, Patelis N, Papasilekas T, Themistoklis K, Spartalis M, Troupis T, Nikiteas N
Curr Pharm Des 2021;27(21):2505-2511. doi: 10.2174/1381612826666200922154824. PMID: 32962609
Tessler I, Adi M, Diment J, Lahav Y, Halperin D, Cohen O
Eur Arch Otorhinolaryngol 2020 Sep;277(9):2551-2558. Epub 2020 Apr 11 doi: 10.1007/s00405-020-05959-z. PMID: 32279105
Kettle AG, O'Doherty MJ
Semin Nucl Med 2006 Jul;36(3):206-11. doi: 10.1053/j.semnuclmed.2006.03.003. PMID: 16762611

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