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Skin carcinoma

MedGen UID:
195945
•Concept ID:
C0699893
•
Neoplastic Process
Synonym: Nonmelanoma skin cancer
 
Monarch Initiative: MONDO:0002656

Definition

A carcinoma that arises from the skin. Representative examples are basal cell carcinoma and squamous cell carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSkin carcinoma

Professional guidelines

PubMed

Advancements in nanoparticle-based treatment approaches for skin cancer therapy.
Zeng L, Gowda BHJ, Ahmed MG, Abourehab MAS, Chen ZS, Zhang C, Li J, Kesharwani P
Mol Cancer 2023 Jan 12;22(1):10. doi: 10.1186/s12943-022-01708-4. PMID: 36635761Free PMC Article
Advanced nanomedicine approaches applied for treatment of skin carcinoma.
Kaur H, Kesharwani P
J Control Release 2021 Sep 10;337:589-611. Epub 2021 Aug 6 doi: 10.1016/j.jconrel.2021.08.003. PMID: 34364919
The risk of transmitting cutaneous malignancy through skin transplantation: a literature-based risk assessment.
Bosma S, Van Wijk MJ, Richters CD, Beele H
Cell Tissue Bank 2015 Dec;16(4):503-12. Epub 2015 Jan 29 doi: 10.1007/s10561-015-9497-6. PMID: 25631853

Recent clinical studies

Etiology

Non-Melanoma Skin Carcinomas of the Head and Neck.
Krišto B, Krželj Vidović I, Krželj A, Perković R
Psychiatr Danub 2021 Dec;33(Suppl 13):308-313. PMID: 35150500
Reducing non-melanoma skin cancer risk in renal transplant recipients.
Thet Z, Lam AK, Ranganathan D, Aung SY, Han T, Khoo TK
Nephrology (Carlton) 2021 Nov;26(11):907-919. Epub 2021 Jul 28 doi: 10.1111/nep.13939. PMID: 34240786
The Mouse Papillomavirus Infection Model.
Hu J, Cladel NM, Budgeon LR, Balogh KK, Christensen ND
Viruses 2017 Aug 30;9(9) doi: 10.3390/v9090246. PMID: 28867783Free PMC Article
Skin carcinoma of the head and neck with perineural invasion.
Balamucki CJ, Mancuso AA, Amdur RJ, Kirwan JM, Morris CG, Flowers FP, Stoer CB, Cognetta AB, Mendenhall WM
Am J Otolaryngol 2012 Jul-Aug;33(4):447-54. Epub 2011 Dec 19 doi: 10.1016/j.amjoto.2011.11.004. PMID: 22185685
Epidemiology of basal cell carcinoma.
Chinem VP, Miot HA
An Bras Dermatol 2011 Mar-Apr;86(2):292-305. doi: 10.1590/s0365-05962011000200013. PMID: 21603813

Diagnosis

Microcystic adnexal carcinoma-diagnostic criteria and therapeutic methods: case report and review of the literature.
Mamic M, Manojlovic L, Suton P, Luksic I
Int J Oral Maxillofac Surg 2018 Oct;47(10):1258-1262. Epub 2018 Mar 27 doi: 10.1016/j.ijom.2018.03.001. PMID: 29602625
Viruses in cancers among the immunosuppressed.
Arroyo Mühr LS, Bzhalava Z, Hortlund M, Lagheden C, Nordqvist Kleppe S, Bzhalava D, Hultin E, Dillner J
Int J Cancer 2017 Dec 15;141(12):2498-2504. Epub 2017 Sep 13 doi: 10.1002/ijc.31017. PMID: 28840939
Studying risk factors for skin cancer development.
Оshyvalova ОО
Wiad Lek 2017;70(3 pt 1):503-507. PMID: 28711897
Skin adnexal carcinoma of the head and neck: a retrospective study in a tertiary referral center.
Stam H, van de Wiel BA, Klop WMC, Zupan-Kajcovski B, Janssens S, Karakullukcu MB, van der Noort V, Lohuis PJFM
Eur Arch Otorhinolaryngol 2015 Apr;272(4):1001-1010. Epub 2014 Oct 16 doi: 10.1007/s00405-014-3324-8. PMID: 25318689
Epidemiology of basal cell carcinoma.
Chinem VP, Miot HA
An Bras Dermatol 2011 Mar-Apr;86(2):292-305. doi: 10.1590/s0365-05962011000200013. PMID: 21603813

Therapy

Recent advances in nanotechnology based combination drug therapy for skin cancer.
Kumari S, Choudhary PK, Shukla R, Sahebkar A, Kesharwani P
J Biomater Sci Polym Ed 2022 Aug;33(11):1435-1468. Epub 2022 Mar 24 doi: 10.1080/09205063.2022.2054399. PMID: 35294334
Reducing non-melanoma skin cancer risk in renal transplant recipients.
Thet Z, Lam AK, Ranganathan D, Aung SY, Han T, Khoo TK
Nephrology (Carlton) 2021 Nov;26(11):907-919. Epub 2021 Jul 28 doi: 10.1111/nep.13939. PMID: 34240786
Viruses in cancers among the immunosuppressed.
Arroyo Mühr LS, Bzhalava Z, Hortlund M, Lagheden C, Nordqvist Kleppe S, Bzhalava D, Hultin E, Dillner J
Int J Cancer 2017 Dec 15;141(12):2498-2504. Epub 2017 Sep 13 doi: 10.1002/ijc.31017. PMID: 28840939
Spontaneous and antiviral-induced cutaneous lesions in chronic hepatitis B virus infection.
Grigorescu I, Dumitrascu DL
World J Gastroenterol 2014 Nov 14;20(42):15860-6. doi: 10.3748/wjg.v20.i42.15860. PMID: 25400473Free PMC Article
Kangri cancer.
Wani I
Surgery 2010 Apr;147(4):586-8. Epub 2009 Nov 24 doi: 10.1016/j.surg.2009.10.025. PMID: 19932909

Prognosis

Reducing non-melanoma skin cancer risk in renal transplant recipients.
Thet Z, Lam AK, Ranganathan D, Aung SY, Han T, Khoo TK
Nephrology (Carlton) 2021 Nov;26(11):907-919. Epub 2021 Jul 28 doi: 10.1111/nep.13939. PMID: 34240786
Skin carcinoma of the head and neck with perineural invasion.
Balamucki CJ, Mancuso AA, Amdur RJ, Kirwan JM, Morris CG, Flowers FP, Stoer CB, Cognetta AB, Mendenhall WM
Am J Otolaryngol 2012 Jul-Aug;33(4):447-54. Epub 2011 Dec 19 doi: 10.1016/j.amjoto.2011.11.004. PMID: 22185685
Epidemiology of basal cell carcinoma.
Chinem VP, Miot HA
An Bras Dermatol 2011 Mar-Apr;86(2):292-305. doi: 10.1590/s0365-05962011000200013. PMID: 21603813
The role of metallothionein in oncogenesis and cancer prognosis.
Pedersen MØ, Larsen A, Stoltenberg M, Penkowa M
Prog Histochem Cytochem 2009;44(1):29-64. Epub 2008 Dec 1 doi: 10.1016/j.proghi.2008.10.001. PMID: 19348910
Principles of management of basal and squamous cell carcinoma of the skin.
Fleming ID, Amonette R, Monaghan T, Fleming MD
Cancer 1995 Jan 15;75(2 Suppl):699-704. doi: 10.1002/1097-0142(19950115)75:2+<699::aid-cncr2820751413>3.0.co;2-q. PMID: 7804997

Clinical prediction guides

Distinct regulations driving YAP1 expression loss in poroma, porocarcinoma and RB1-deficient skin carcinoma.
Kervarrec T, Frouin E, Collin C, Tallet A, Tallegas M, Pissaloux D, Tirode F, Guyétant S, Samimi M, Gaboriaud P, Touzé A, Schrama D, Houben R, Tabareau-Delalande F, Neuhart A, de la Fouchardière A, Osio A, Cavelier-Balloy B, Laurent-Roussel S, Sohier P, Cyprien T, Balme B, Belzung F, Jullie ML, Cribier B, Battistella M, Macagno N
Histopathology 2023 May;82(6):885-898. Epub 2023 Feb 22 doi: 10.1111/his.14874. PMID: 36720791
Reducing non-melanoma skin cancer risk in renal transplant recipients.
Thet Z, Lam AK, Ranganathan D, Aung SY, Han T, Khoo TK
Nephrology (Carlton) 2021 Nov;26(11):907-919. Epub 2021 Jul 28 doi: 10.1111/nep.13939. PMID: 34240786
Second Primary Cancers in Patients with Invasive and In Situ Squamous Cell Skin Carcinoma, Kaposi Sarcoma, and Merkel Cell Carcinoma: Role for Immune Mechanisms?
Chattopadhyay S, Hemminki A, Försti A, Sundquist K, Sundquist J, Hemminki K
J Invest Dermatol 2020 Jan;140(1):48-55.e1. Epub 2019 Jul 6 doi: 10.1016/j.jid.2019.04.031. PMID: 31288011
A review of head and neck cancer staging system in the TNM classification of malignant tumors (eighth edition).
Head and Neck Cancer Study Group (HNCSG), Monden N, Asakage T, Kiyota N, Homma A, Matsuura K, Hanai N, Kodaira T, Zenda S, Fujii H, Tahara M, Yokota T, Akimoto T, Iwae S, Onitsuka T, Ogawa T, Okano S, Takahashi S, Shimizu Y, Yonezawa K, Hayashi R
Jpn J Clin Oncol 2019 Jul 1;49(7):589-595. doi: 10.1093/jjco/hyz052. PMID: 31194232
Long-term consequences of renal insufficiency in children: lessons learned from the Dutch LERIC study.
Groothoff JW, Offringa M, Grootenhuis M, Jager KJ
Nephrol Dial Transplant 2018 Apr 1;33(4):552-560. doi: 10.1093/ndt/gfx190. PMID: 28992218

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