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Cerebellar astrocytoma

MedGen UID:
196631
Concept ID:
C0740480
Neoplastic Process
Synonyms: astrocytoma (excluding glioblastoma) of cerebellum; Astrocytoma of Cerebellum; astrocytoma of cerebellum; Astrocytoma of the Cerebellum; astrocytoma of the cerebellum; Astrocytoma, Cerebellar; astrocytoma, cerebellar; Cerebellar Astrocytoma; cerebellar astrocytoma; cerebellum astrocytoma; cerebellum astrocytoma (excluding glioblastoma)
 
Monarch Initiative: MONDO:0003165

Definition

Benign and malignant neoplasms of the cerebellum that arise from astrocytes. During childhood the majority are benign pilocytic astrocytomas. In adults both benign and relatively higher grade forms may occur. The most common presenting symptoms are headache, nausea, vomiting, ataxia of gait or limb, paresis, diplopia, and dizziness. Objective signs include weakness, long tract signs, dysmetria, gait ataxia, papilledema, and nystagmus. Surgical resection is often curative. [from NCI]

Professional guidelines

PubMed

Due-Tønnessen BJ, Lundar T, Egge A, Scheie D
J Neurosurg Pediatr 2013 Mar;11(3):245-9. Epub 2012 Dec 14 doi: 10.3171/2012.11.PEDS12265. PMID: 23240848
Moreno-Torres A, Martínez-Pérez I, Baquero M, Campistol J, Capdevila A, Arús C, Pujol J
Neurosurgery 2004 Oct;55(4):824-9; discussion 829. doi: 10.1227/01.neu.0000137655.53303.c8. PMID: 15458590
Larson DA, Wara WM, Edwards MS
Int J Radiat Oncol Biol Phys 1990 Apr;18(4):971-3. doi: 10.1016/0360-3016(90)90425-j. PMID: 2323983

Recent clinical studies

Etiology

Nouraeinejad A
Graefes Arch Clin Exp Ophthalmol 2023 Dec;261(12):3347-3354. Epub 2023 May 5 doi: 10.1007/s00417-023-06092-3. PMID: 37145335Free PMC Article
Vinchon M, Leblond P
Neurochirurgie 2021 Feb;67(1):23-27. Epub 2019 Sep 5 doi: 10.1016/j.neuchi.2019.04.006. PMID: 31494131
Due-Tønnessen BJ, Lundar T, Egge A, Scheie D
J Neurosurg Pediatr 2013 Mar;11(3):245-9. Epub 2012 Dec 14 doi: 10.3171/2012.11.PEDS12265. PMID: 23240848
Hirano A, Hirano M
Neuropathology 2004 Mar;24(1):1-7. doi: 10.1111/j.1440-1789.2003.00526.x. PMID: 15068166
Rashidi M, DaSilva VR, Minagar A, Rutka JT
Curr Neurol Neurosci Rep 2003 May;3(3):200-5. doi: 10.1007/s11910-003-0079-9. PMID: 12691624

Diagnosis

Vinchon M, Leblond P
Neurochirurgie 2021 Feb;67(1):23-27. Epub 2019 Sep 5 doi: 10.1016/j.neuchi.2019.04.006. PMID: 31494131
Brandão LA, Young Poussaint T
Neuroimaging Clin N Am 2017 Feb;27(1):1-37. doi: 10.1016/j.nic.2016.08.001. PMID: 27889018
Bonfield CM, Steinbok P
Childs Nerv Syst 2015 Oct;31(10):1677-85. Epub 2015 Sep 9 doi: 10.1007/s00381-015-2719-1. PMID: 26351221
Hirano A, Hirano M
Neuropathology 2004 Mar;24(1):1-7. doi: 10.1111/j.1440-1789.2003.00526.x. PMID: 15068166
Rashidi M, DaSilva VR, Minagar A, Rutka JT
Curr Neurol Neurosci Rep 2003 May;3(3):200-5. doi: 10.1007/s11910-003-0079-9. PMID: 12691624

Therapy

Keezer MR, Del Maestro R
Can J Neurol Sci 2009 May;36(3):303-10. doi: 10.1017/s0317167100007022. PMID: 19534329
Richter S, Schoch B, Kaiser O, Groetschel H, Dimitrova A, Hein-Kropp C, Maschke M, Gizewski ER, Timmann D
Neurosci Lett 2005 Jun 10-17;381(1-2):102-7. Epub 2005 Feb 25 doi: 10.1016/j.neulet.2005.02.011. PMID: 15882798
Viano JC, Herrera EJ, Suárez JC
Childs Nerv Syst 2001 Oct;17(10):607-10; discussion 611. doi: 10.1007/s003810100479. PMID: 11685523
Furuta T, Sugiu K, Tamiya T, Matsumoto K, Ohmoto T
Clin Neurol Neurosurg 1998 Mar;100(1):56-9. doi: 10.1016/s0303-8467(97)00122-4. PMID: 9637208
Mandigers CM, Lippens RJ, Hoogenhout J, Meijer E, von Wieringen PM, Theeuwes AG
Pediatr Hematol Oncol 1990;7(2):121-8. doi: 10.3109/08880019009033381. PMID: 1698433

Prognosis

Vinchon M, Leblond P
Neurochirurgie 2021 Feb;67(1):23-27. Epub 2019 Sep 5 doi: 10.1016/j.neuchi.2019.04.006. PMID: 31494131
Riva D, Taddei M, Ghielmetti F, Erbetta A, Bulgheroni S
Cerebellum 2019 Aug;18(4):791-806. doi: 10.1007/s12311-019-01039-z. PMID: 31111430
Bonfield CM, Steinbok P
Childs Nerv Syst 2015 Oct;31(10):1677-85. Epub 2015 Sep 9 doi: 10.1007/s00381-015-2719-1. PMID: 26351221
Rashidi M, DaSilva VR, Minagar A, Rutka JT
Curr Neurol Neurosci Rep 2003 May;3(3):200-5. doi: 10.1007/s11910-003-0079-9. PMID: 12691624
Ilgren EB, Stiller CA
Clin Neuropathol 1987 Sep-Oct;6(5):185-200. PMID: 3319331

Clinical prediction guides

Vinchon M, Leblond P
Neurochirurgie 2021 Feb;67(1):23-27. Epub 2019 Sep 5 doi: 10.1016/j.neuchi.2019.04.006. PMID: 31494131
Riva D, Taddei M, Ghielmetti F, Erbetta A, Bulgheroni S
Cerebellum 2019 Aug;18(4):791-806. doi: 10.1007/s12311-019-01039-z. PMID: 31111430
Hirano A, Hirano M
Neuropathology 2004 Mar;24(1):1-7. doi: 10.1111/j.1440-1789.2003.00526.x. PMID: 15068166
Viano JC, Herrera EJ, Suárez JC
Childs Nerv Syst 2001 Oct;17(10):607-10; discussion 611. doi: 10.1007/s003810100479. PMID: 11685523
Ilgren EB, Stiller CA
Clin Neuropathol 1987 Sep-Oct;6(5):185-200. PMID: 3319331

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