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Cerebral astrocytoma

MedGen UID:
196691
•Concept ID:
C0750935
•
Neoplastic Process
Synonyms: Astrocytoma, Cerebral; Cerebral Astrocytoma; Cerebral Astrocytomas
SNOMED CT: Astrocytoma of cerebrum (99131000119108)
 
Monarch Initiative: MONDO:0021633

Definition

An astrocytoma that arises from the cerebral hemispheres. [from NCI]

Professional guidelines

PubMed

Radiation therapy in the treatment of cerebral astrocytoma.
Morantz RA
Neurosurgery 1987 Jun;20(6):975-82. doi: 10.1227/00006123-198706000-00028. PMID: 3614580
Treatment of low-grade cerebral astrocytoma: new methods and evaluation of results.
Koivukangas J, Koivukangas P
Ann Clin Res 1986;18 Suppl 47:115-24. PMID: 3545036
Recent concepts in the conservative treatment of intracranial tumours in children.
Bloom HJ
Acta Neurochir (Wien) 1979;50(1-2):103-16. doi: 10.1007/BF01813555. PMID: 229698

Recent clinical studies

Etiology

Factores asociados con supervivencia a cinco años en niños con astrocitoma cerebral.
Sevilla-Castillo RA, Andrade-Sarmiento LA
Gac Med Mex 2018;154(3):283-286. doi: 10.24875/GMM.17003116. PMID: 30047946
Novel suprasellar location of desmoplastic infantile astrocytoma and ganglioglioma: a single institution's experience.
Naylor RM, Wohl A, Raghunathan A, Eckel LJ, Keating GF, Daniels DJ
J Neurosurg Pediatr 2018 Oct;22(4):397-403. Epub 2018 Jul 6 doi: 10.3171/2018.4.PEDS17638. PMID: 29979130Free PMC Article
Radiological features of infantile glioblastoma and desmoplastic infantile tumors: British Columbia's Children's Hospital experience.
Bader A, Heran M, Dunham C, Steinbok P
J Neurosurg Pediatr 2015 Aug;16(2):119-25. Epub 2015 May 8 doi: 10.3171/2014.10.PEDS13634. PMID: 25955808
A biobehavioral perspective on depressive symptoms in patients with cerebral astrocytoma.
Starkweather AR, Sherwood P, Lyon DE, McCain NL, Bovbjerg DH, Broaddus WC
J Neurosci Nurs 2011 Feb;43(1):17-28. doi: 10.1097/jnn.0b013e3182029859. PMID: 21338041Free PMC Article
An analysis of 38 cases of low-grade cerebral astrocytoma in adults.
Jubelirer SJ, Rubin M, Shim C
W V Med J 1993 Mar;89(3):102-5. PMID: 8475621

Diagnosis

The relationship between MRI quantitative parameters and the expression of hypoxia inducible factor-1 alpha in cerebral astrocytoma.
Shu C, Wang J
Clin Neurol Neurosurg 2017 Feb;153:14-19. Epub 2016 Nov 23 doi: 10.1016/j.clineuro.2016.11.013. PMID: 28006727
Desmoplastic astrocytoma: new insights into its clinical profile, diagnosis, and treatment.
Rojas-Medina LM, Carrasco-Moro R, Rivero-Garvía M, Esteban-Fernández L, Rivas-Infante E, Márquez-Rivas J
Childs Nerv Syst 2016 Sep;32(9):1577-85. Epub 2016 Sep 1 doi: 10.1007/s00381-016-3126-y. PMID: 27624454
Radiological features of infantile glioblastoma and desmoplastic infantile tumors: British Columbia's Children's Hospital experience.
Bader A, Heran M, Dunham C, Steinbok P
J Neurosurg Pediatr 2015 Aug;16(2):119-25. Epub 2015 May 8 doi: 10.3171/2014.10.PEDS13634. PMID: 25955808
A biobehavioral perspective on depressive symptoms in patients with cerebral astrocytoma.
Starkweather AR, Sherwood P, Lyon DE, McCain NL, Bovbjerg DH, Broaddus WC
J Neurosci Nurs 2011 Feb;43(1):17-28. doi: 10.1097/jnn.0b013e3182029859. PMID: 21338041Free PMC Article
Metastatic astrocytoma.
Dewar JM, Dady PJ, Balakrishnan V
Aust N Z J Med 1985 Dec;15(6):745-7. PMID: 3010926

Therapy

Desmoplastic astrocytoma: new insights into its clinical profile, diagnosis, and treatment.
Rojas-Medina LM, Carrasco-Moro R, Rivero-Garvía M, Esteban-Fernández L, Rivas-Infante E, Márquez-Rivas J
Childs Nerv Syst 2016 Sep;32(9):1577-85. Epub 2016 Sep 1 doi: 10.1007/s00381-016-3126-y. PMID: 27624454
PET Imaging of cerebral astrocytoma with 13N-ammonia.
Xiangsong Z, Changhong L, Weian C, Dong Z
J Neurooncol 2006 Jun;78(2):145-51. Epub 2006 May 13 doi: 10.1007/s11060-005-9069-x. PMID: 16739028
Radiation therapy in the treatment of cerebral astrocytoma.
Morantz RA
Neurosurgery 1987 Jun;20(6):975-82. doi: 10.1227/00006123-198706000-00028. PMID: 3614580
A randomized study of misonidazole and radiotherapy for grade 3 and 4 cerebral astrocytoma.
Bleehen NM, Wiltshire CR, Plowman PN, Watson JV, Gleave JR, Holmes AE, Lewin WS, Treip CS, Hawkins TD
Br J Cancer 1981 Apr;43(4):436-42. doi: 10.1038/bjc.1981.64. PMID: 7016157Free PMC Article
Clinical studies with misonidazole.
Wiltshire CR, Workman P, Watson JV, Bleehen NM
Br J Cancer Suppl 1978 Jun;3:286-9. PMID: 277246Free PMC Article

Prognosis

The value of intravoxel incoherent motion imaging in predicting the survival of patients with astrocytoma.
Zhu L, Wu J, Zhang H, Niu H, Wang L
Acta Radiol 2021 Mar;62(3):423-429. Epub 2020 Jun 17 doi: 10.1177/0284185120926907. PMID: 32551800
Factores asociados con supervivencia a cinco años en niños con astrocitoma cerebral.
Sevilla-Castillo RA, Andrade-Sarmiento LA
Gac Med Mex 2018;154(3):283-286. doi: 10.24875/GMM.17003116. PMID: 30047946
Novel suprasellar location of desmoplastic infantile astrocytoma and ganglioglioma: a single institution's experience.
Naylor RM, Wohl A, Raghunathan A, Eckel LJ, Keating GF, Daniels DJ
J Neurosurg Pediatr 2018 Oct;22(4):397-403. Epub 2018 Jul 6 doi: 10.3171/2018.4.PEDS17638. PMID: 29979130Free PMC Article
An analysis of 38 cases of low-grade cerebral astrocytoma in adults.
Jubelirer SJ, Rubin M, Shim C
W V Med J 1993 Mar;89(3):102-5. PMID: 8475621
Desmoplastic infantile ganglioglioma and desmoplastic cerebral astrocytoma of infancy.
VandenBerg SR
Brain Pathol 1993 Jul;3(3):275-81. doi: 10.1111/j.1750-3639.1993.tb00754.x. PMID: 8293187

Clinical prediction guides

Lateralized overgrowth with vascular malformation caused by a somatic PTPN11 pathogenic variant: Another piece added to the puzzle of mosaic RASopathies.
Mussa A, Turchiano A, Cardaropoli S, Coppo P, Pantaleo A, Bagnulo R, Ranieri C, Iacoviello M, Garganese A, Stella A, Vallero SG, Bertin D, Santoro F, Carli D, Ferrero GB, Resta N
Genes Chromosomes Cancer 2022 Nov;61(11):689-695. Epub 2022 Jul 16 doi: 10.1002/gcc.23086. PMID: 35778969Free PMC Article
The value of intravoxel incoherent motion imaging in predicting the survival of patients with astrocytoma.
Zhu L, Wu J, Zhang H, Niu H, Wang L
Acta Radiol 2021 Mar;62(3):423-429. Epub 2020 Jun 17 doi: 10.1177/0284185120926907. PMID: 32551800
Phytometabolite Dehydroleucodine Induces Cell Cycle Arrest, Apoptosis, and DNA Damage in Human Astrocytoma Cells through p73/p53 Regulation.
Bailon-Moscoso N, González-Arévalo G, Velásquez-Rojas G, Malagon O, Vidari G, Zentella-Dehesa A, Ratovitski EA, Ostrosky-Wegman P
PLoS One 2015;10(8):e0136527. Epub 2015 Aug 26 doi: 10.1371/journal.pone.0136527. PMID: 26309132Free PMC Article
PET Imaging of cerebral astrocytoma with 13N-ammonia.
Xiangsong Z, Changhong L, Weian C, Dong Z
J Neurooncol 2006 Jun;78(2):145-51. Epub 2006 May 13 doi: 10.1007/s11060-005-9069-x. PMID: 16739028
Melanotic cerebral astrocytoma: case report and literature review.
Kanzawa T, Takahashi H, Hayano M, Mori S, Shimbo Y, Kitazawa T
Acta Neuropathol 1997 Feb;93(2):200-4. doi: 10.1007/s004010050603. PMID: 9039469

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