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Sciatica

MedGen UID:
19893
Concept ID:
C0036396
Sign or Symptom
Synonyms: Neuralgia, Sciatic; Neuralgias, Sciatic; Sciatic Neuralgia; Sciatic Neuralgias
SNOMED CT: Sciatica neuralgia (23056005); Sciatica (23056005); Neuralgia-neuritis of sciatic nerve (23056005); Sciatic neuralgia (23056005)
 
HPO: HP:0011868
Monarch Initiative: MONDO:0024333

Definition

Pain in the lower back and hip radiating in the distribution of the sciatic nerve. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSciatica

Professional guidelines

PubMed

Zaina F, Côté P, Cancelliere C, Di Felice F, Donzelli S, Rauch A, Verville L, Negrini S, Nordin M
Arch Phys Med Rehabil 2023 Nov;104(11):1913-1927. Epub 2023 Mar 23 doi: 10.1016/j.apmr.2023.02.022. PMID: 36963709
Jensen RK, Kongsted A, Kjaer P, Koes B
BMJ 2019 Nov 19;367:l6273. doi: 10.1136/bmj.l6273. PMID: 31744805
Probst D, Stout A, Hunt D
PM R 2019 Aug;11 Suppl 1:S54-S63. Epub 2019 Jul 22 doi: 10.1002/pmrj.12189. PMID: 31102324

Curated

UK NICE Guideline NG59, Low back pain and sciatica in over 16s: assessment and management, 2020

Recent clinical studies

Etiology

Dove L, Jones G, Kelsey LA, Cairns MC, Schmid AB
Eur Spine J 2023 Feb;32(2):517-533. Epub 2022 Dec 29 doi: 10.1007/s00586-022-07356-y. PMID: 36580149Free PMC Article
Bastos RM, Moya CR, de Vasconcelos RA, Costa LOP
J Man Manip Ther 2022 Aug;30(4):207-227. Epub 2022 Jan 24 doi: 10.1080/10669817.2021.2024677. PMID: 35067217Free PMC Article
Bailey CS, Rasoulinejad P, Taylor D, Sequeira K, Miller T, Watson J, Rosedale R, Bailey SI, Gurr KR, Siddiqi F, Glennie A, Urquhart JC
N Engl J Med 2020 Mar 19;382(12):1093-1102. doi: 10.1056/NEJMoa1912658. PMID: 32187469
Parreira P, Maher CG, Steffens D, Hancock MJ, Ferreira ML
Spine J 2018 Sep;18(9):1715-1721. Epub 2018 May 21 doi: 10.1016/j.spinee.2018.05.018. PMID: 29792997
Peul WC, van Houwelingen HC, van den Hout WB, Brand R, Eekhof JA, Tans JT, Thomeer RT, Koes BW; Leiden-The Hague Spine Intervention Prognostic Study Group
N Engl J Med 2007 May 31;356(22):2245-56. doi: 10.1056/NEJMoa064039. PMID: 17538084

Diagnosis

Jensen RK, Kongsted A, Kjaer P, Koes B
BMJ 2019 Nov 19;367:l6273. doi: 10.1136/bmj.l6273. PMID: 31744805
Valat JP, Genevay S, Marty M, Rozenberg S, Koes B
Best Pract Res Clin Rheumatol 2010 Apr;24(2):241-52. doi: 10.1016/j.berh.2009.11.005. PMID: 20227645
Kirschner JS, Foye PM, Cole JL
Muscle Nerve 2009 Jul;40(1):10-8. doi: 10.1002/mus.21318. PMID: 19466717
Boyajian-O'Neill LA, McClain RL, Coleman MK, Thomas PP
J Am Osteopath Assoc 2008 Nov;108(11):657-64. doi: 10.7556/jaoa.2008.108.11.657. PMID: 19011229
Koes BW, van Tulder MW, Peul WC
BMJ 2007 Jun 23;334(7607):1313-7. doi: 10.1136/bmj.39223.428495.BE. PMID: 17585160Free PMC Article

Therapy

Fu JL, Perloff MD
Drugs Aging 2022 Jul;39(7):523-550. Epub 2022 Jun 27 doi: 10.1007/s40266-022-00946-x. PMID: 35754070
Danazumi MS, Bello B, Yakasai AM, Kaka B
J Osteopath Med 2021 Feb 26;121(4):391-400. doi: 10.1515/jom-2020-0261. PMID: 33705612
Rubinstein SM, de Zoete A, van Middelkoop M, Assendelft WJJ, de Boer MR, van Tulder MW
BMJ 2019 Mar 13;364:l689. doi: 10.1136/bmj.l689. PMID: 30867144Free PMC Article
Coulombe BJ, Games KE, Neil ER, Eberman LE
J Athl Train 2017 Jan;52(1):71-72. Epub 2016 Nov 16 doi: 10.4085/1062-6050-51.11.16. PMID: 27849389Free PMC Article
Koes BW, van Tulder MW, Peul WC
BMJ 2007 Jun 23;334(7607):1313-7. doi: 10.1136/bmj.39223.428495.BE. PMID: 17585160Free PMC Article

Prognosis

Bailey CS, Rasoulinejad P, Taylor D, Sequeira K, Miller T, Watson J, Rosedale R, Bailey SI, Gurr KR, Siddiqi F, Glennie A, Urquhart JC
N Engl J Med 2020 Mar 19;382(12):1093-1102. doi: 10.1056/NEJMoa1912658. PMID: 32187469
Jensen RK, Kongsted A, Kjaer P, Koes B
BMJ 2019 Nov 19;367:l6273. doi: 10.1136/bmj.l6273. PMID: 31744805
Shiri R, Falah-Hassani K, Heliövaara M, Solovieva S, Amiri S, Lallukka T, Burdorf A, Husgafvel-Pursiainen K, Viikari-Juntura E
Arthritis Care Res (Hoboken) 2019 Feb;71(2):290-299. doi: 10.1002/acr.23710. PMID: 30044543
Gugliotta M, da Costa BR, Dabis E, Theiler R, Jüni P, Reichenbach S, Landolt H, Hasler P
BMJ Open 2016 Dec 21;6(12):e012938. doi: 10.1136/bmjopen-2016-012938. PMID: 28003290Free PMC Article
Koes BW, van Tulder MW, Peul WC
BMJ 2007 Jun 23;334(7607):1313-7. doi: 10.1136/bmj.39223.428495.BE. PMID: 17585160Free PMC Article

Clinical prediction guides

Liu C, Ferreira GE, Abdel Shaheed C, Chen Q, Harris IA, Bailey CS, Peul WC, Koes B, Lin CC
BMJ 2023 Apr 19;381:e070730. doi: 10.1136/bmj-2022-070730. PMID: 37076169Free PMC Article
Bastos RM, Moya CR, de Vasconcelos RA, Costa LOP
J Man Manip Ther 2022 Aug;30(4):207-227. Epub 2022 Jan 24 doi: 10.1080/10669817.2021.2024677. PMID: 35067217Free PMC Article
Bailey CS, Rasoulinejad P, Taylor D, Sequeira K, Miller T, Watson J, Rosedale R, Bailey SI, Gurr KR, Siddiqi F, Glennie A, Urquhart JC
N Engl J Med 2020 Mar 19;382(12):1093-1102. doi: 10.1056/NEJMoa1912658. PMID: 32187469
Dower A, Davies MA, Ghahreman A
World Neurosurg 2019 Aug;128:114-121. Epub 2019 Apr 25 doi: 10.1016/j.wneu.2019.04.147. PMID: 31028982
Peul WC, van Houwelingen HC, van den Hout WB, Brand R, Eekhof JA, Tans JT, Thomeer RT, Koes BW; Leiden-The Hague Spine Intervention Prognostic Study Group
N Engl J Med 2007 May 31;356(22):2245-56. doi: 10.1056/NEJMoa064039. PMID: 17538084

Recent systematic reviews

Liu C, Ferreira GE, Abdel Shaheed C, Chen Q, Harris IA, Bailey CS, Peul WC, Koes B, Lin CC
BMJ 2023 Apr 19;381:e070730. doi: 10.1136/bmj-2022-070730. PMID: 37076169Free PMC Article
Zaina F, Côté P, Cancelliere C, Di Felice F, Donzelli S, Rauch A, Verville L, Negrini S, Nordin M
Arch Phys Med Rehabil 2023 Nov;104(11):1913-1927. Epub 2023 Mar 23 doi: 10.1016/j.apmr.2023.02.022. PMID: 36963709
Dove L, Jones G, Kelsey LA, Cairns MC, Schmid AB
Eur Spine J 2023 Feb;32(2):517-533. Epub 2022 Dec 29 doi: 10.1007/s00586-022-07356-y. PMID: 36580149Free PMC Article
van der Windt DA, Simons E, Riphagen II, Ammendolia C, Verhagen AP, Laslett M, Devillé W, Deyo RA, Bouter LM, de Vet HC, Aertgeerts B
Cochrane Database Syst Rev 2010 Feb 17;(2):CD007431. doi: 10.1002/14651858.CD007431.pub2. PMID: 20166095
Jordan J, Konstantinou K, O'Dowd J
BMJ Clin Evid 2009 Mar 26;2009 PMID: 19445754Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2020
      UK NICE Guideline NG59, Low back pain and sciatica in over 16s: assessment and management, 2020

    Consumer resources

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