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Median nerve neuropathy

MedGen UID:
199766
Concept ID:
C0751922
Disease or Syndrome
Synonyms: Median Mononeuropathies; Median Mononeuropathy; Median Nerve Disease; Median Nerve Diseases; Median Nerve Neuropathies; Median Nerve Neuropathy; Median Neuropathies; Median Neuropathy; Mononeuropathy, Median; Nerve Disease, Median; Nerve Neuropathy, Median; Neuropathy, Median; Neuropathy, Median Nerve
SNOMED CT: Median neuropathy (397828008); Median nerve palsy (397828008)
 
Monarch Initiative: MONDO:0003598

Definition

Disease involving the median nerve, from its origin at the brachial plexus to its termination in the hand. Clinical features include weakness of wrist and finger flexion, forearm pronation, thenar abduction, and loss of sensation over the lateral palm, first three fingers, and radial half of the ring finger. Common sites of injury include the elbow, where the nerve passes through the two heads of the pronator teres muscle (pronator syndrome) and in the carpal tunnel (carpal tunnel syndrome). [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMedian nerve neuropathy

Professional guidelines

PubMed

Ruch DS, Papadonikolakis A
J Hand Surg Am 2006 Jan;31(1):9-16. doi: 10.1016/j.jhsa.2005.09.011. PMID: 16443097

Recent clinical studies

Etiology

Twardowska M, Czarnecki P, Jokiel M, Bręborowicz E, Huber J, Romanowski L
Medicina (Kaunas) 2023 Jul 31;59(8) doi: 10.3390/medicina59081404. PMID: 37629694Free PMC Article
Lee JH, Kim KJ, Baek JH
Orthopedics 2021 May-Jun;44(3):e367-e372. Epub 2021 May 1 doi: 10.3928/01477447-20210414-08. PMID: 34039199
Iyer V
J Clin Neurophysiol 2019 Jul;36(4):312-315. doi: 10.1097/WNP.0000000000000590. PMID: 31033651
Aboonq MS
Neurosciences (Riyadh) 2015 Jan;20(1):4-9. PMID: 25630774Free PMC Article
Potulska-Chromik A, Lipowska M, Gawel M, Ryniewicz B, Maj E, Kostera-Pruszczyk A
J Child Neurol 2014 Feb;29(2):227-31. Epub 2013 Oct 1 doi: 10.1177/0883073813504458. PMID: 24084629

Diagnosis

Glin M, Zielinska N, Ruzik K, Karauda P, Konschake M, Olewnik Ł
Surg Radiol Anat 2023 Sep;45(9):1125-1134. Epub 2023 Aug 2 doi: 10.1007/s00276-023-03198-5. PMID: 37530816Free PMC Article
Potulska-Chromik A, Lipowska M, Gawel M, Ryniewicz B, Maj E, Kostera-Pruszczyk A
J Child Neurol 2014 Feb;29(2):227-31. Epub 2013 Oct 1 doi: 10.1177/0883073813504458. PMID: 24084629
El Falougy H, Selmeciova P, Kubikova E, Stenova J, Haviarova Z
Bratisl Lek Listy 2013;114(5):290-4. doi: 10.4149/bll_2013_061. PMID: 23611054
Hunter JM
Hand Clin 1996 May;12(2):365-78. PMID: 8724588
Benson MD, Cohen AS, Brandt KD, Cathcart ES
Lancet 1975 Jan 4;1(7897):10-2. doi: 10.1016/s0140-6736(75)92373-9. PMID: 46335

Therapy

Lee JH, Kim KJ, Baek JH
Orthopedics 2021 May-Jun;44(3):e367-e372. Epub 2021 May 1 doi: 10.3928/01477447-20210414-08. PMID: 34039199
Gary C, Shah A, Kanouzi J, Golas AR, Frey JD, Le B, Hacquebord J, Thanik V
Hand (N Y) 2017 Sep;12(5):NP157-NP161. Epub 2017 May 16 doi: 10.1177/1558944717708053. PMID: 28511570Free PMC Article
Celik G, Ilik MK
J Clin Neurophysiol 2016 Apr;33(2):166-70. doi: 10.1097/WNP.0000000000000243. PMID: 26657237
Vasenius J
Scand J Surg 2008;97(4):290-6; discussion 296-7. doi: 10.1177/145749690809700403. PMID: 19211382
Dickerman RD, Douglas JA, East JW
Arch Phys Med Rehabil 2000 Dec;81(12):1594-5. doi: 10.1053/apmr.2000.7159. PMID: 11128896

Prognosis

Lee JH, Kim KJ, Baek JH
Orthopedics 2021 May-Jun;44(3):e367-e372. Epub 2021 May 1 doi: 10.3928/01477447-20210414-08. PMID: 34039199
Wee E, Nikpour M, Balta S, Williams RA, Kelly RI
Australas J Dermatol 2018 Aug;59(3):223-225. Epub 2018 Apr 6 doi: 10.1111/ajd.12798. PMID: 29624649
Kim JM, Harris MB, Zurakowski D, Liu W, Jupiter JB, Kim JH, Vrahas MS
J Surg Orthop Adv 2017 WINTER;26(4):227-232. PMID: 29461195
El Falougy H, Selmeciova P, Kubikova E, Stenova J, Haviarova Z
Bratisl Lek Listy 2013;114(5):290-4. doi: 10.4149/bll_2013_061. PMID: 23611054
Cara J, Narvaez A, de la Varga V, Guerado E
Acta Orthop Belg 1998 Mar;64(1):100-3. PMID: 9586259

Clinical prediction guides

Twardowska M, Czarnecki P, Jokiel M, Bręborowicz E, Huber J, Romanowski L
Medicina (Kaunas) 2023 Jul 31;59(8) doi: 10.3390/medicina59081404. PMID: 37629694Free PMC Article
Lee JH, Kim KJ, Baek JH
Orthopedics 2021 May-Jun;44(3):e367-e372. Epub 2021 May 1 doi: 10.3928/01477447-20210414-08. PMID: 34039199
Uemura T, Takamatsu K, Okada M, Yokoi T, Onode E, Miyashima Y, Konishi S, Nakamura H
J Plast Reconstr Aesthet Surg 2020 Mar;73(3):453-459. Epub 2019 Oct 11 doi: 10.1016/j.bjps.2019.09.051. PMID: 31757685
El Falougy H, Selmeciova P, Kubikova E, Stenova J, Haviarova Z
Bratisl Lek Listy 2013;114(5):290-4. doi: 10.4149/bll_2013_061. PMID: 23611054
Gomes I, Becker J, Ehlers JA, Nora DB
Clin Neurophysiol 2006 May;117(5):964-71. Epub 2006 Mar 3 doi: 10.1016/j.clinph.2005.12.020. PMID: 16516550

Recent systematic reviews

Glin M, Zielinska N, Ruzik K, Karauda P, Konschake M, Olewnik Ł
Surg Radiol Anat 2023 Sep;45(9):1125-1134. Epub 2023 Aug 2 doi: 10.1007/s00276-023-03198-5. PMID: 37530816Free PMC Article

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