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Glossopharyngeal nerve disorder

MedGen UID:
199771
•Concept ID:
C0751941
•
Disease or Syndrome
Synonym: Glossopharyngeal nerve disease
SNOMED CT: Disorder of ninth nerve (80962007); Glossopharyngeal nerve lesion (80962007); Disorder of IXth cranial nerve (80962007); Disorder of glossopharyngeal nerve (80962007); Disorder of the ninth cranial nerve (80962007); Glossopharyngeal nerve disorder (80962007)
 
Monarch Initiative: MONDO:0002639

Definition

A non-neoplastic or neoplastic disorder affecting the glossopharyngeal nerve (ninth cranial nerve). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGlossopharyngeal nerve disorder

Professional guidelines

PubMed

Medication Management of Neuropathic Pain Disorders.
Fisher R, Clarkson E
Dent Clin North Am 2024 Jan;68(1):121-131. Epub 2023 Aug 30 doi: 10.1016/j.cden.2023.07.010. PMID: 37951629
CRANIAL NERVE HYPERFUNCTION SYNDROMES. MODERN APPROACHES TO DIAGNOSIS AND TREATMENT (REVIEW).
Sirko A, Chekha K, Mizyakina K
Georgian Med News 2020 Jun;(303):113-120. PMID: 32841192
Glossopharyngeal neuralgia: neurosurgical treatment and differential diagnosis.
Teixeira MJ, de Siqueira SR, Bor-Seng-Shu E
Acta Neurochir (Wien) 2008 May;150(5):471-5; discussion 475. Epub 2008 Feb 4 doi: 10.1007/s00701-007-1493-6. PMID: 18231706

Recent clinical studies

Etiology

Collet-Sicard syndrome: a scoping review.
Aguilera-Pena MP, Castiblanco MA, Osejo-Arcos V, Aponte-Caballero R, Gutierrez-Gomez S, Abaunza-Camacho JF, Guevara-Moriones N, Benavides-Burbano CA, Riveros-Castillo WM, Saavedra JM
Neurosurg Rev 2023 Sep 14;46(1):244. doi: 10.1007/s10143-023-02145-7. PMID: 37707587
Risk factors of post-tonsillectomy dysgeusia.
Kitaya S, Kikuchi T, Yahata I, Ikeda R, Nomura K, Kawase T, Katori Y
Auris Nasus Larynx 2020 Apr;47(2):238-241. Epub 2019 Jul 16 doi: 10.1016/j.anl.2019.07.005. PMID: 31324400
Sex, Gender, and Orofacial Pain.
Shaefer JR, Khawaja SN, Bavia PF
Dent Clin North Am 2018 Oct;62(4):665-682. Epub 2018 Aug 2 doi: 10.1016/j.cden.2018.06.001. PMID: 30189989
Glossopharyngeal neuralgia and radiosurgery.
Martínez-Álvarez R, Martínez-Moreno N, Kusak ME, Rey-Portolés G
J Neurosurg 2014 Dec;121 Suppl:222-5. doi: 10.3171/2014.8.GKS141273. PMID: 25434956
Clinical manifestations of carotid dissection.
Baumgartner R, Bogousslavsky J
Front Neurol Neurosci 2005;20:70-76. doi: 10.1159/000088151. PMID: 17290113

Diagnosis

Imaging of Cranial Neuralgias.
Kanekar S, Saif M, Kanekar S
Neurol Clin 2022 Aug;40(3):591-607. Epub 2022 Jun 28 doi: 10.1016/j.ncl.2022.02.008. PMID: 35871786
Pediatric glossopharyngeal neuralgia: a comprehensive review.
Shereen R, Gardner B, Altafulla J, Simonds E, Iwanaga J, Litvack Z, Loukas M, Shane Tubbs R
Childs Nerv Syst 2019 Mar;35(3):395-402. Epub 2018 Oct 25 doi: 10.1007/s00381-018-3995-3. PMID: 30361762
Neuropathic Orofacial Pain.
Christoforou J
Dent Clin North Am 2018 Oct;62(4):565-584. Epub 2018 Jul 31 doi: 10.1016/j.cden.2018.05.005. PMID: 30189983
Cranial Neuralgias.
Tepper SJ
Continuum (Minneap Minn) 2018 Aug;24(4, Headache):1157-1178. doi: 10.1212/CON.0000000000000637. PMID: 30074554
Cranial Neuralgias.
Cheshire WP Jr
Continuum (Minneap Minn) 2015 Aug;21(4 Headache):1072-85. doi: 10.1212/CON.0000000000000194. PMID: 26252592

Therapy

Effects of Antimalarial Drugs on Neuroinflammation-Potential Use for Treatment of COVID-19-Related Neurologic Complications.
Ong WY, Go ML, Wang DY, Cheah IK, Halliwell B
Mol Neurobiol 2021 Jan;58(1):106-117. Epub 2020 Sep 8 doi: 10.1007/s12035-020-02093-z. PMID: 32897518Free PMC Article
Trigeminal and glossopharyngeal neuralgia.
Reddy GD, Viswanathan A
Neurol Clin 2014 May;32(2):539-52. Epub 2013 Dec 28 doi: 10.1016/j.ncl.2013.11.008. PMID: 24703544
Cranial neuralgias.
Hupp WS, Firriolo FJ
Dent Clin North Am 2013 Jul;57(3):481-95. Epub 2013 May 21 doi: 10.1016/j.cden.2013.04.009. PMID: 23809305
Medical management of trigeminal neuropathic pains.
Zakrzewska JM
Expert Opin Pharmacother 2010 Jun;11(8):1239-54. doi: 10.1517/14656561003767449. PMID: 20426709
Vagolysis.
Hutchinson CD, Jardine DL, Hurrell M
Age Ageing 2008 Sep;37(5):602-4. Epub 2008 Jun 12 doi: 10.1093/ageing/afn105. PMID: 18556705

Prognosis

Lower cranial nerve syndromes: a review.
Gutierrez S, Warner T, McCormack E, Werner C, Mathkour M, Iwanaga J, Uz A, Dumont AS, Tubbs RS
Neurosurg Rev 2021 Jun;44(3):1345-1355. Epub 2020 Jul 8 doi: 10.1007/s10143-020-01344-w. PMID: 32638140
Glossopharyngeal neuralgia and radiosurgery.
Martínez-Álvarez R, Martínez-Moreno N, Kusak ME, Rey-Portolés G
J Neurosurg 2014 Dec;121 Suppl:222-5. doi: 10.3171/2014.8.GKS141273. PMID: 25434956
Lateral congenital anomalies of the pharyngeal apparatus: part II. anatomy of the abnormal for the surgeon.
Mirilas P
Am Surg 2011 Sep;77(9):1243-56. PMID: 21944635
Vagolysis.
Hutchinson CD, Jardine DL, Hurrell M
Age Ageing 2008 Sep;37(5):602-4. Epub 2008 Jun 12 doi: 10.1093/ageing/afn105. PMID: 18556705
The glossopharyngeal nerve, glossopharyngeal neuralgia and the Eagle's syndrome--current concepts and management.
Soh KB
Singapore Med J 1999 Oct;40(10):659-65. PMID: 10741197

Clinical prediction guides

Transient glossopharyngeal nerve palsy due to mandibular nerve block.
Papadopoulou M, Anastasakis S
BMJ Case Rep 2022 Jul 25;15(7) doi: 10.1136/bcr-2022-251033. PMID: 35878966Free PMC Article
MRI Findings and Outcomes in Patients Undergoing Microvascular Decompression for Glossopharyngeal Neuralgia.
Jani RH, Hughes MA, Ligus ZE, Nikas A, Sekula RF
J Neuroimaging 2018 Sep;28(5):477-482. Epub 2018 Aug 13 doi: 10.1111/jon.12554. PMID: 30102011
Fleece-Bound Tissue Sealing in Microvascular Decompression.
Tanrikulu L, Buchfelder M, Naraghi R
Turk Neurosurg 2017;27(5):763-767. doi: 10.5137/1019-5149.JTN.17462-16.2. PMID: 27593828
Glossopharyngeal neuralgia and radiosurgery.
Martínez-Álvarez R, Martínez-Moreno N, Kusak ME, Rey-Portolés G
J Neurosurg 2014 Dec;121 Suppl:222-5. doi: 10.3171/2014.8.GKS141273. PMID: 25434956
Clinical manifestations of carotid dissection.
Baumgartner R, Bogousslavsky J
Front Neurol Neurosci 2005;20:70-76. doi: 10.1159/000088151. PMID: 17290113

Recent systematic reviews

Current advances in the surgical treatment of glossopharyngeal neuralgia.
Berckemeyer MA, Suarez-Meade P, Carcelen MFV, Ricci MD, Cheshire WP, Trifiletti DM, Middlebrooks EH, Quinones-Hinojosa A, Grewal SS
Neurosurg Rev 2023 Feb 2;46(1):47. doi: 10.1007/s10143-023-01948-y. PMID: 36725770
Cranial Nerve Disorders Associated With Immune Checkpoint Inhibitors.
Vogrig A, Muñiz-Castrillo S, Joubert B, Picard G, Rogemond V, Skowron F, Egri M, Desestret V, Tilikete C, Psimaras D, Ducray F, Honnorat J
Neurology 2021 Feb 9;96(6):e866-e875. Epub 2020 Dec 14 doi: 10.1212/WNL.0000000000011340. PMID: 33318162
Repeat Gamma Knife Radiosurgery for Recurrent Glossopharyngeal Neuralgia: A Systematic Review and Our Initial Experience.
Kaye J, Daggubati LC, Zeller S, McInerney J
Stereotact Funct Neurosurg 2020;98(5):324-330. Epub 2020 Aug 18 doi: 10.1159/000508541. PMID: 32810861
Glossopharyngeal Neuralgia Treatment Outcomes After Nerve Section, Microvascular Decompression, or Stereotactic Radiosurgery: A Systematic Review and Meta-Analysis.
Lu VM, Goyal A, Graffeo CS, Perry A, Jonker BP, Link MJ
World Neurosurg 2018 Dec;120:572-582.e7. Epub 2018 Sep 18 doi: 10.1016/j.wneu.2018.09.042. PMID: 30240868
Pharyngolaryngeal involvement by varicella-zoster virus.
Nisa L, Landis BN, Giger R, Leuchter I
J Voice 2013 Sep;27(5):636-41. Epub 2013 Jun 12 doi: 10.1016/j.jvoice.2013.02.011. PMID: 23769009

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