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Sleep deprivation

MedGen UID:
19998
•Concept ID:
C0037316
•
Finding
Synonyms: Deprivation, Sleep; Sleep Deprivation
SNOMED CT: Sleep deprivation (130989002); Lack of adequate sleep (130989002)

Definition

The state of being deprived of sleep under experimental conditions, due to life events, or from a wide variety of pathophysiologic causes such as medication effect, chronic illness, psychiatric illness, or sleep disorder. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSleep deprivation

Professional guidelines

PubMed

Delirium in Older Persons: Advances in Diagnosis and Treatment.
Oh ES, Fong TG, Hshieh TT, Inouye SK
JAMA 2017 Sep 26;318(12):1161-1174. doi: 10.1001/jama.2017.12067. PMID: 28973626Free PMC Article
Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder: Section 5. Complementary and Alternative Medicine Treatments.
Ravindran AV, Balneaves LG, Faulkner G, Ortiz A, McIntosh D, Morehouse RL, Ravindran L, Yatham LN, Kennedy SH, Lam RW, MacQueen GM, Milev RV, Parikh SV; CANMAT Depression Work Group
Can J Psychiatry 2016 Sep;61(9):576-87. Epub 2016 Aug 2 doi: 10.1177/0706743716660290. PMID: 27486153Free PMC Article
Treatment-refractory anxiety; definition, risk factors, and treatment challenges.
Roy-Byrne P
Dialogues Clin Neurosci 2015 Jun;17(2):191-206. doi: 10.31887/DCNS.2015.17.2/proybyrne. PMID: 26246793Free PMC Article

Recent clinical studies

Etiology

Sleep deprivation and its association with diseases- a review.
Liew SC, Aung T
Sleep Med 2021 Jan;77:192-204. Epub 2020 Aug 18 doi: 10.1016/j.sleep.2020.07.048. PMID: 32951993
Sleep Disorders in Adolescents.
Kansagra S
Pediatrics 2020 May;145(Suppl 2):S204-S209. doi: 10.1542/peds.2019-2056I. PMID: 32358212
Insufficient sleep in adolescents: causes and consequences.
Owens JA, Weiss MR
Minerva Pediatr 2017 Aug;69(4):326-336. Epub 2017 Feb 17 doi: 10.23736/S0026-4946.17.04914-3. PMID: 28211649
Sleep deprivation increases formation of false memory.
Lo JC, Chong PL, Ganesan S, Leong RL, Chee MW
J Sleep Res 2016 Dec;25(6):673-682. Epub 2016 Jul 5 doi: 10.1111/jsr.12436. PMID: 27381857Free PMC Article
Sleep Deprivation.
Abrams RM
Obstet Gynecol Clin North Am 2015 Sep;42(3):493-506. doi: 10.1016/j.ogc.2015.05.013. PMID: 26333639

Diagnosis

Sleep Disorders in Adolescents.
Kansagra S
Pediatrics 2020 May;145(Suppl 2):S204-S209. doi: 10.1542/peds.2019-2056I. PMID: 32358212
Sleep, insomnia, and depression.
Riemann D, Krone LB, Wulff K, Nissen C
Neuropsychopharmacology 2020 Jan;45(1):74-89. Epub 2019 May 9 doi: 10.1038/s41386-019-0411-y. PMID: 31071719Free PMC Article
Insufficient sleep in adolescents and young adults: an update on causes and consequences.
Owens J; Adolescent Sleep Working Group; Committee on Adolescence
Pediatrics 2014 Sep;134(3):e921-32. doi: 10.1542/peds.2014-1696. PMID: 25157012Free PMC Article
Role of sleep and sleep loss in hormonal release and metabolism.
Leproult R, Van Cauter E
Endocr Dev 2010;17:11-21. Epub 2009 Nov 24 doi: 10.1159/000262524. PMID: 19955752Free PMC Article
Neurocognitive consequences of sleep deprivation.
Durmer JS, Dinges DF
Semin Neurol 2005 Mar;25(1):117-29. doi: 10.1055/s-2005-867080. PMID: 15798944

Therapy

Sleepiness, sleep deprivation, quality of life, mental symptoms and perception of academic environment in medical students.
Perotta B, Arantes-Costa FM, Enns SC, Figueiro-Filho EA, Paro H, Santos IS, Lorenzi-Filho G, Martins MA, Tempski PZ
BMC Med Educ 2021 Feb 17;21(1):111. doi: 10.1186/s12909-021-02544-8. PMID: 33596885Free PMC Article
Influence of sleep restriction on weight loss outcomes associated with caloric restriction.
Wang X, Sparks JR, Bowyer KP, Youngstedt SD
Sleep 2018 May 1;41(5) doi: 10.1093/sleep/zsy027. PMID: 29438540Free PMC Article
Dietary Sources and Bioactivities of Melatonin.
Meng X, Li Y, Li S, Zhou Y, Gan RY, Xu DP, Li HB
Nutrients 2017 Apr 7;9(4) doi: 10.3390/nu9040367. PMID: 28387721Free PMC Article
In Search of a Safe Natural Sleep Aid.
Rao TP, Ozeki M, Juneja LR
J Am Coll Nutr 2015;34(5):436-47. Epub 2015 Mar 11 doi: 10.1080/07315724.2014.926153. PMID: 25759004
The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation.
Van Dongen HP, Maislin G, Mullington JM, Dinges DF
Sleep 2003 Mar 15;26(2):117-26. doi: 10.1093/sleep/26.2.117. PMID: 12683469

Prognosis

Association of sleep duration in middle and old age with incidence of dementia.
Sabia S, Fayosse A, Dumurgier J, van Hees VT, Paquet C, Sommerlad A, Kivimäki M, Dugravot A, Singh-Manoux A
Nat Commun 2021 Apr 20;12(1):2289. doi: 10.1038/s41467-021-22354-2. PMID: 33879784Free PMC Article
Sleep Irregularity and Risk of Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis.
Huang T, Mariani S, Redline S
J Am Coll Cardiol 2020 Mar 10;75(9):991-999. doi: 10.1016/j.jacc.2019.12.054. PMID: 32138974Free PMC Article
Sleep in Women Across the Life Span.
Pengo MF, Won CH, Bourjeily G
Chest 2018 Jul;154(1):196-206. Epub 2018 Apr 19 doi: 10.1016/j.chest.2018.04.005. PMID: 29679598Free PMC Article
The prospective association between sleep deprivation and depression among adolescents.
Roberts RE, Duong HT
Sleep 2014 Feb 1;37(2):239-44. doi: 10.5665/sleep.3388. PMID: 24497652Free PMC Article
Sleep duration and all-cause mortality: a systematic review and meta-analysis of prospective studies.
Cappuccio FP, D'Elia L, Strazzullo P, Miller MA
Sleep 2010 May;33(5):585-92. doi: 10.1093/sleep/33.5.585. PMID: 20469800Free PMC Article

Clinical prediction guides

Sleepiness, sleep deprivation, quality of life, mental symptoms and perception of academic environment in medical students.
Perotta B, Arantes-Costa FM, Enns SC, Figueiro-Filho EA, Paro H, Santos IS, Lorenzi-Filho G, Martins MA, Tempski PZ
BMC Med Educ 2021 Feb 17;21(1):111. doi: 10.1186/s12909-021-02544-8. PMID: 33596885Free PMC Article
Association Between Sleep Duration and Cognitive Decline.
Ma Y, Liang L, Zheng F, Shi L, Zhong B, Xie W
JAMA Netw Open 2020 Sep 1;3(9):e2013573. doi: 10.1001/jamanetworkopen.2020.13573. PMID: 32955572Free PMC Article
Consequences of inadequate sleep during the college years: Sleep deprivation, grade point average, and college graduation.
Chen WL, Chen JH
Prev Med 2019 Jul;124:23-28. Epub 2019 Apr 26 doi: 10.1016/j.ypmed.2019.04.017. PMID: 31034864
Sleep-deprivation and autobiographical memory: evidence from sleep-deprived nurses.
Zare Khormizi H, Salehinejad MA, Nitsche MA, Nejati V
J Sleep Res 2019 Feb;28(1):e12683. Epub 2018 Apr 6 doi: 10.1111/jsr.12683. PMID: 29624749
Sleep deprivation and the effect on exercise performance.
VanHelder T, Radomski MW
Sports Med 1989 Apr;7(4):235-47. doi: 10.2165/00007256-198907040-00002. PMID: 2657963

Recent systematic reviews

The effect of caffeine on subsequent sleep: A systematic review and meta-analysis.
Gardiner C, Weakley J, Burke LM, Roach GD, Sargent C, Maniar N, Townshend A, Halson SL
Sleep Med Rev 2023 Jun;69:101764. Epub 2023 Feb 6 doi: 10.1016/j.smrv.2023.101764. PMID: 36870101
Long sleep duration and health outcomes: A systematic review, meta-analysis and meta-regression.
Jike M, Itani O, Watanabe N, Buysse DJ, Kaneita Y
Sleep Med Rev 2018 Jun;39:25-36. Epub 2017 Jul 5 doi: 10.1016/j.smrv.2017.06.011. PMID: 28890167
Short sleep duration and health outcomes: a systematic review, meta-analysis, and meta-regression.
Itani O, Jike M, Watanabe N, Kaneita Y
Sleep Med 2017 Apr;32:246-256. Epub 2016 Aug 26 doi: 10.1016/j.sleep.2016.08.006. PMID: 27743803
Sleep Disturbance, Sleep Duration, and Inflammation: A Systematic Review and Meta-Analysis of Cohort Studies and Experimental Sleep Deprivation.
Irwin MR, Olmstead R, Carroll JE
Biol Psychiatry 2016 Jul 1;80(1):40-52. Epub 2015 Jun 1 doi: 10.1016/j.biopsych.2015.05.014. PMID: 26140821Free PMC Article
Screen time and sleep among school-aged children and adolescents: a systematic literature review.
Hale L, Guan S
Sleep Med Rev 2015 Jun;21:50-8. Epub 2014 Aug 12 doi: 10.1016/j.smrv.2014.07.007. PMID: 25193149Free PMC Article

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