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Retinal drusen

MedGen UID:
20549
Concept ID:
C0035312
Disease or Syndrome
Synonyms: Drusen, Retinal; Retinal Drusen
SNOMED CT: Colloid bodies in retina (247153005); Retinal drusen (247153005)
 
Monarch Initiative: MONDO:0006949

Definition

Colloid or hyaline bodies lying beneath the retinal pigment epithelium. They may occur either secondary to changes in the choroid that affect the pigment epithelium or as an autosomal dominant disorder of the retinal pigment epithelium. [from MONDO]

Term Hierarchy

Professional guidelines

PubMed

Gu C, Wang Y, Jiang Y, Xu F, Wang S, Liu R, Yuan W, Abudureyimu N, Wang Y, Lu Y, Li X, Wu T, Dong L, Chen Y, Wang B, Zhang Y, Wei WB, Qiu Q, Zheng Z, Liu D, Chen J
Br J Ophthalmol 2024 Feb 21;108(3):424-431. doi: 10.1136/bjo-2022-322940. PMID: 36878715Free PMC Article
Sibony PA, Kupersmith MJ, Kardon RH
J Neuroophthalmol 2021 Mar 1;41(1):77-92. doi: 10.1097/WNO.0000000000001078. PMID: 32909979Free PMC Article
Seddon JM, Reynolds R, Rosner B
Invest Ophthalmol Vis Sci 2009 Feb;50(2):586-91. Epub 2008 Oct 20 doi: 10.1167/iovs.08-2514. PMID: 18936151Free PMC Article

Recent clinical studies

Therapy

Agrón E, Mares J, Clemons TE, Swaroop A, Chew EY, Keenan TDL; AREDS and AREDS2 Research Groups
Ophthalmology 2021 Mar;128(3):425-442. Epub 2020 Aug 25 doi: 10.1016/j.ophtha.2020.08.018. PMID: 32858063Free PMC Article
Waldstein SM, Vogl WD, Bogunovic H, Sadeghipour A, Riedl S, Schmidt-Erfurth U
JAMA Ophthalmol 2020 Jul 1;138(7):740-747. doi: 10.1001/jamaophthalmol.2020.1376. PMID: 32379287Free PMC Article
Markowitz SN, Devenyi RG, Munk MR, Croissant CL, Tedford SE, Rückert R, Walker MG, Patino BE, Chen L, Nido M, Tedford CE
Retina 2020 Aug;40(8):1471-1482. doi: 10.1097/IAE.0000000000002632. PMID: 31404033Free PMC Article
Nowak JZ
Pharmacol Rep 2006 May-Jun;58(3):353-63. PMID: 16845209
Ophthalmology 1991 May;98(5 Suppl):786-806. PMID: 2062513

Prognosis

Pandya BU, Grinton M, Mandelcorn ED, Felfeli T
Retina 2024 Mar 1;44(3):369-380. doi: 10.1097/IAE.0000000000003974. PMID: 37903455Free PMC Article
Keenan TDL, Cukras CA, Chew EY
Adv Exp Med Biol 2021;1256:1-31. doi: 10.1007/978-3-030-66014-7_1. PMID: 33847996
Zhang X, Sivaprasad S
Eye (Lond) 2021 Jan;35(1):121-133. Epub 2020 Nov 18 doi: 10.1038/s41433-020-01265-4. PMID: 33208847Free PMC Article
Agrón E, Mares J, Clemons TE, Swaroop A, Chew EY, Keenan TDL; AREDS and AREDS2 Research Groups
Ophthalmology 2021 Mar;128(3):425-442. Epub 2020 Aug 25 doi: 10.1016/j.ophtha.2020.08.018. PMID: 32858063Free PMC Article
Waldstein SM, Vogl WD, Bogunovic H, Sadeghipour A, Riedl S, Schmidt-Erfurth U
JAMA Ophthalmol 2020 Jul 1;138(7):740-747. doi: 10.1001/jamaophthalmol.2020.1376. PMID: 32379287Free PMC Article

Clinical prediction guides

Pandya BU, Grinton M, Mandelcorn ED, Felfeli T
Retina 2024 Mar 1;44(3):369-380. doi: 10.1097/IAE.0000000000003974. PMID: 37903455Free PMC Article
Keenan TDL, Cukras CA, Chew EY
Adv Exp Med Biol 2021;1256:1-31. doi: 10.1007/978-3-030-66014-7_1. PMID: 33847996
Agrón E, Mares J, Clemons TE, Swaroop A, Chew EY, Keenan TDL; AREDS and AREDS2 Research Groups
Ophthalmology 2021 Mar;128(3):425-442. Epub 2020 Aug 25 doi: 10.1016/j.ophtha.2020.08.018. PMID: 32858063Free PMC Article
Waldstein SM, Vogl WD, Bogunovic H, Sadeghipour A, Riedl S, Schmidt-Erfurth U
JAMA Ophthalmol 2020 Jul 1;138(7):740-747. doi: 10.1001/jamaophthalmol.2020.1376. PMID: 32379287Free PMC Article
Markowitz SN, Devenyi RG, Munk MR, Croissant CL, Tedford SE, Rückert R, Walker MG, Patino BE, Chen L, Nido M, Tedford CE
Retina 2020 Aug;40(8):1471-1482. doi: 10.1097/IAE.0000000000002632. PMID: 31404033Free PMC Article

Recent systematic reviews

Paul SK, Pan I, Sobol WM
Retina 2022 Aug 1;42(8):1417-1424. doi: 10.1097/IAE.0000000000003535. PMID: 35877964
Eng VA, Wood EH, Boddu S, Karth PA, Leng T
Ophthalmic Surg Lasers Imaging Retina 2019 Mar 1;50(3):e61-e70. doi: 10.3928/23258160-20190301-13. PMID: 30893458
Gheorghe A, Mahdi L, Musat O
Rom J Ophthalmol 2015 Apr-Jun;59(2):74-7. PMID: 26978865Free PMC Article
Virgili G, Michelessi M, Parodi MB, Bacherini D, Evans JR
Cochrane Database Syst Rev 2015 Oct 23;2015(10):CD006537. doi: 10.1002/14651858.CD006537.pub3. PMID: 26493180Free PMC Article
Parodi MB, Virgili G, Evans JR
Cochrane Database Syst Rev 2009 Jul 8;(3):CD006537. doi: 10.1002/14651858.CD006537.pub2. PMID: 19588397

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