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Rickettsiosis

MedGen UID:
20584
•Concept ID:
C0035585
•
Disease or Syndrome
Synonym: Rickettsial disease
SNOMED CT: Rickettsial disease (37246009); Disease due to Rickettsiales (409904000); Disease due to Rickettsia (416829003); Disease due to Genus Rickettsia (416829003); Rickettsiosis (416829003); Disease caused by rickettsiae (37246009); Rickettsial infectious disease (409904000); Rickettsial infection (409904000); Disease caused by Rickettsia (416829003); Disease caused by Genus Rickettsia (416829003); Disease caused by Rickettsiales (409904000)
 
Monarch Initiative: MONDO:0006956
Orphanet: ORPHA102021

Definition

A group of infectious diseases that is caused by Rickettsia. [from NCI]

Professional guidelines

PubMed

Patient characteristics, treatment patterns, and outcomes of Rickettsial diseases among a commercially insured population in the United States, 2005-2017.
Binder AM, Armstrong PA
Sci Rep 2021 Sep 15;11(1):18382. doi: 10.1038/s41598-021-96463-9. PMID: 34526545Free PMC Article
Lyme borreliosis and other tick-borne diseases. Guidelines from the French Scientific Societies (I): prevention, epidemiology, diagnosis.
Figoni J, Chirouze C, Hansmann Y, Lemogne C, Hentgen V, Saunier A, Bouiller K, Gehanno JF, Rabaud C, Perrot S, Caumes E, Eldin C, de Broucker T, Jaulhac B, Roblot F, Toubiana J, Sellal F, Vuillemet F, Sordet C, Fantin B, Lina G, Gocko X, Dieudonné M, Picone O, Bodaghi B, Gangneux JP, Degeilh B, Partouche H, Lenormand C, Sotto A, Raffetin A, Monsuez JJ, Michel C, Boulanger N, Cathebras P, Tattevin P; endorsed by scientific societies
Med Mal Infect 2019 Aug;49(5):318-334. Epub 2019 May 13 doi: 10.1016/j.medmal.2019.04.381. PMID: 31097370
Antibiotic treatment of rickettsiosis, recent advances and current concepts.
Raoult D
Eur J Epidemiol 1991 May;7(3):276-81. doi: 10.1007/BF00145677. PMID: 1884779

Recent clinical studies

Etiology

Rickettsia-Host-Tick Interactions: Knowledge Advances and Gaps.
Kim HK
Infect Immun 2022 Sep 15;90(9):e0062121. Epub 2022 Aug 22 doi: 10.1128/iai.00621-21. PMID: 35993770Free PMC Article
Clinical characteristics of Rocky Mountain spotted fever in the United States: A literature review.
Jay R, Armstrong PA
J Vector Borne Dis 2020 Apr-Jun;57(2):114-120. doi: 10.4103/0972-9062.310863. PMID: 34290155
Emerging and re-emerging rickettsial infections.
Adem PV
Semin Diagn Pathol 2019 May;36(3):146-151. Epub 2019 Apr 16 doi: 10.1053/j.semdp.2019.04.005. PMID: 31101391
Rickettsioses in Europe.
Portillo A, Santibáñez S, García-Álvarez L, Palomar AM, Oteo JA
Microbes Infect 2015 Nov-Dec;17(11-12):834-8. Epub 2015 Sep 16 doi: 10.1016/j.micinf.2015.09.009. PMID: 26384814
Neglected bacterial zoonoses.
Chikeka I, Dumler JS
Clin Microbiol Infect 2015 May;21(5):404-15. Epub 2015 May 8 doi: 10.1016/j.cmi.2015.04.022. PMID: 25964152Free PMC Article

Diagnosis

Emerging and re-emerging rickettsial infections.
Adem PV
Semin Diagn Pathol 2019 May;36(3):146-151. Epub 2019 Apr 16 doi: 10.1053/j.semdp.2019.04.005. PMID: 31101391
Lyme borreliosis and other tick-borne diseases. Guidelines from the French Scientific Societies (I): prevention, epidemiology, diagnosis.
Figoni J, Chirouze C, Hansmann Y, Lemogne C, Hentgen V, Saunier A, Bouiller K, Gehanno JF, Rabaud C, Perrot S, Caumes E, Eldin C, de Broucker T, Jaulhac B, Roblot F, Toubiana J, Sellal F, Vuillemet F, Sordet C, Fantin B, Lina G, Gocko X, Dieudonné M, Picone O, Bodaghi B, Gangneux JP, Degeilh B, Partouche H, Lenormand C, Sotto A, Raffetin A, Monsuez JJ, Michel C, Boulanger N, Cathebras P, Tattevin P; endorsed by scientific societies
Med Mal Infect 2019 Aug;49(5):318-334. Epub 2019 May 13 doi: 10.1016/j.medmal.2019.04.381. PMID: 31097370
Rickettsioses in Europe.
Portillo A, Santibáñez S, García-Álvarez L, Palomar AM, Oteo JA
Microbes Infect 2015 Nov-Dec;17(11-12):834-8. Epub 2015 Sep 16 doi: 10.1016/j.micinf.2015.09.009. PMID: 26384814
Neglected bacterial zoonoses.
Chikeka I, Dumler JS
Clin Microbiol Infect 2015 May;21(5):404-15. Epub 2015 May 8 doi: 10.1016/j.cmi.2015.04.022. PMID: 25964152Free PMC Article
Childhood rickettsiosis.
Kulkarni A
Indian J Pediatr 2011 Jan;78(1):81-7. Epub 2010 Oct 22 doi: 10.1007/s12098-010-0255-2. PMID: 20967515

Therapy

Emerging Spotted Fever Rickettsioses in the United States.
Kidd L
Vet Clin North Am Small Anim Pract 2022 Nov;52(6):1305-1317. doi: 10.1016/j.cvsm.2022.07.003. PMID: 36336422
Clinical characteristics of Rocky Mountain spotted fever in the United States: A literature review.
Jay R, Armstrong PA
J Vector Borne Dis 2020 Apr-Jun;57(2):114-120. doi: 10.4103/0972-9062.310863. PMID: 34290155
African Tick-Bite Fever.
Fralish MS, Mangalindan KE, Farris CM, Jiang J, Green MC, Blaylock JM
Am J Med 2020 Sep;133(9):1051-1053. Epub 2020 Apr 20 doi: 10.1016/j.amjmed.2020.03.031. PMID: 32325042
Revisiting doxycycline in pregnancy and early childhood--time to rebuild its reputation?
Cross R, Ling C, Day NP, McGready R, Paris DH
Expert Opin Drug Saf 2016;15(3):367-82. Epub 2016 Jan 25 doi: 10.1517/14740338.2016.1133584. PMID: 26680308Free PMC Article
Childhood rickettsiosis.
Kulkarni A
Indian J Pediatr 2011 Jan;78(1):81-7. Epub 2010 Oct 22 doi: 10.1007/s12098-010-0255-2. PMID: 20967515

Prognosis

Emerging Spotted Fever Rickettsioses in the United States.
Kidd L
Vet Clin North Am Small Anim Pract 2022 Nov;52(6):1305-1317. doi: 10.1016/j.cvsm.2022.07.003. PMID: 36336422
Analysis of Orientia tsutsugamushi promoter activity.
Hunt JR, Carlyon JA
Pathog Dis 2021 Sep 23;79(7) doi: 10.1093/femspd/ftab044. PMID: 34515306Free PMC Article
Neuroinflammation associated with scrub typhus and spotted fever group rickettsioses.
Fisher J, Card G, Soong L
PLoS Negl Trop Dis 2020 Oct;14(10):e0008675. Epub 2020 Oct 22 doi: 10.1371/journal.pntd.0008675. PMID: 33091013Free PMC Article
Repellents as a major element in the context of prevention of tick-borne diseases.
Przygodzka M, Mikulak E, Chmielewski T, Gliniewicz A
Przegl Epidemiol 2019;73(2):269-280. doi: 10.32394/pe.73.25. PMID: 31385684
Neglected bacterial zoonoses.
Chikeka I, Dumler JS
Clin Microbiol Infect 2015 May;21(5):404-15. Epub 2015 May 8 doi: 10.1016/j.cmi.2015.04.022. PMID: 25964152Free PMC Article

Clinical prediction guides

Clinical Characteristics and Diagnostic Prediction of Severe Fever with Thrombocytopenia Syndrome and Rickettsiosis in the Co-Endemic Wakayama Prefecture, Japan.
Teramoto K, Tamura S, Yoshida K, Inada Y, Yamashita Y, Morimoto M, Mushino T, Koreeda D, Miyamoto K, Komiya N, Nakano Y, Takagaki Y, Koizumi Y
Medicina (Kaunas) 2023 Nov 17;59(11) doi: 10.3390/medicina59112024. PMID: 38004073Free PMC Article
Analysis of Orientia tsutsugamushi promoter activity.
Hunt JR, Carlyon JA
Pathog Dis 2021 Sep 23;79(7) doi: 10.1093/femspd/ftab044. PMID: 34515306Free PMC Article
Distinguishing Japanese Spotted Fever and Scrub Typhus, Central Japan, 2004- 2015.
Sando E, Suzuki M, Katoh S, Fujita H, Taira M, Yaegashi M, Ariyoshi K
Emerg Infect Dis 2018 Sep;24(9):1633-1641. doi: 10.3201/eid2409.171436. PMID: 30124190Free PMC Article
Rickettsiae and rickettsial diseases in Croatia: Implications for travel medicine.
Dzelalija B, Punda-Polic V, Medic A, Dobec M
Travel Med Infect Dis 2016 Sep-Oct;14(5):436-443. Epub 2016 Jul 9 doi: 10.1016/j.tmaid.2016.06.010. PMID: 27404664
Tick-borne rickettsioses in international travellers.
Jensenius M, Fournier PE, Raoult D
Int J Infect Dis 2004 May;8(3):139-46. doi: 10.1016/j.ijid.2003.06.004. PMID: 15109588

Recent systematic reviews

Rickettsiales in the WHO European Region: an update from a One Health perspective.
Guccione C, Colomba C, Iaria C, Cascio A
Parasit Vectors 2023 Jan 30;16(1):41. doi: 10.1186/s13071-022-05646-4. PMID: 36717936Free PMC Article
Laboratory Methods for Detection of Infectious Agents and Serological Response in Humans With Tick-Borne Infections: A Systematic Review of Evaluations Based on Clinical Patient Samples.
Henningsson AJ, Aase A, Bavelaar H, Flottorp S, Forsberg P, Kirkehei I, Lövmar M, Nilsson K, Nyman D, Ornstein K, Sjöwall J, Skogman BH, Tjernberg I, Aaberge I
Front Public Health 2021;9:580102. Epub 2021 Sep 20 doi: 10.3389/fpubh.2021.580102. PMID: 34616701Free PMC Article
Clinical, epidemiological, and laboratory features of Rickettsia parkeri rickettsiosis: A systematic review.
Silva-Ramos CR, Hidalgo M, Faccini-Martínez ÁA
Ticks Tick Borne Dis 2021 Jul;12(4):101734. Epub 2021 May 1 doi: 10.1016/j.ttbdis.2021.101734. PMID: 33989945
Tick-borne zoonoses in the Order Rickettsiales and Legionellales in Iran: A systematic review.
Khamesipour F, Dida GO, Anyona DN, Razavi SM, Rakhshandehroo E
PLoS Negl Trop Dis 2018 Sep;12(9):e0006722. Epub 2018 Sep 11 doi: 10.1371/journal.pntd.0006722. PMID: 30204754Free PMC Article
Revisiting doxycycline in pregnancy and early childhood--time to rebuild its reputation?
Cross R, Ling C, Day NP, McGready R, Paris DH
Expert Opin Drug Saf 2016;15(3):367-82. Epub 2016 Jan 25 doi: 10.1517/14740338.2016.1133584. PMID: 26680308Free PMC Article

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