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Schizotypal personality disorder

MedGen UID:
20666
Concept ID:
C0036363
Mental or Behavioral Dysfunction
Synonyms: Disorder, Schizotypal Personality; Disorders, Schizotypal Personality; Personality Disorder, Schizotypal; Personality Disorders, Schizotypal; Schizotypal Personality Disorder; Schizotypal Personality Disorders
SNOMED CT: Schizoptypal disorder (31027006); Schizotypal personality disorder (31027006)
 
Monarch Initiative: MONDO:0001087

Definition

A disorder characterized by an enduring pattern of inability to establish close relationships coupled with cognitive or perceptual distortions, odd beliefs and speech, and eccentric behavior and appearance. [from NCI]

Professional guidelines

PubMed

Stone MH
Psychodyn Psychiatry 2022 Spring;50(1):45-63. doi: 10.1521/pdps.2022.50.1.45. PMID: 35235397
Cheli S
Psychiatr Rehabil J 2020 Dec;43(4):335-343. Epub 2020 May 28 doi: 10.1037/prj0000429. PMID: 32463252
Jakobsen KD, Skyum E, Hashemi N, Schjerning O, Fink-Jensen A, Nielsen J
J Psychopharmacol 2017 Apr;31(4):397-405. Epub 2017 Mar 14 doi: 10.1177/0269881117695879. PMID: 28347257

Recent clinical studies

Etiology

Sher L
Acta Neuropsychiatr 2021 Oct;33(5):280-282. Epub 2021 Jul 8 doi: 10.1017/neu.2021.19. PMID: 34233771
Apthorp D, Bolbecker AR, Bartolomeo LA, O'Donnell BF, Hetrick WP
Schizophr Bull 2019 Apr 25;45(3):512-521. doi: 10.1093/schbul/sby141. PMID: 30376125Free PMC Article
Balaratnasingam S, Janca A
Curr Opin Psychiatry 2015 Jan;28(1):30-4. doi: 10.1097/YCO.0000000000000124. PMID: 25415496
Rosell DR, Futterman SE, McMaster A, Siever LJ
Curr Psychiatry Rep 2014 Jul;16(7):452. doi: 10.1007/s11920-014-0452-1. PMID: 24828284Free PMC Article
Häfner H, an der Heiden W
Can J Psychiatry 1997 Mar;42(2):139-51. doi: 10.1177/070674379704200204. PMID: 9067063

Diagnosis

Kwapil TR, Barrantes-Vidal N
Personal Disord 2022 Jul;13(4):392-396. doi: 10.1037/per0000538. PMID: 35787127
Sher L
Acta Neuropsychiatr 2021 Oct;33(5):280-282. Epub 2021 Jul 8 doi: 10.1017/neu.2021.19. PMID: 34233771
Jakobsen KD, Skyum E, Hashemi N, Schjerning O, Fink-Jensen A, Nielsen J
J Psychopharmacol 2017 Apr;31(4):397-405. Epub 2017 Mar 14 doi: 10.1177/0269881117695879. PMID: 28347257
Chemerinski E, Triebwasser J, Roussos P, Siever LJ
J Pers Disord 2013 Oct;27(5):652-79. Epub 2012 Aug 28 doi: 10.1521/pedi_2012_26_053. PMID: 22928856
Häfner H, an der Heiden W
Can J Psychiatry 1997 Mar;42(2):139-51. doi: 10.1177/070674379704200204. PMID: 9067063

Therapy

Nielsen KD, Hovmand OR, Jørgensen MS, Meisner M, Arnfred SM
Clin Psychol Psychother 2023 Nov-Dec;30(6):1264-1278. Epub 2023 Sep 7 doi: 10.1002/cpp.2901. PMID: 37675964
Hazan H, Reese E, Linscott RJ
Early Interv Psychiatry 2022 Jan;16(1):26-33. Epub 2021 Feb 8 doi: 10.1111/eip.13125. PMID: 33559381
Rocamora-Montenegro M, Compañ-Gabucio LM, Garcia de la Hera M
BMJ Open 2021 Oct 29;11(10):e047467. doi: 10.1136/bmjopen-2020-047467. PMID: 34716157Free PMC Article
Jakobsen KD, Skyum E, Hashemi N, Schjerning O, Fink-Jensen A, Nielsen J
J Psychopharmacol 2017 Apr;31(4):397-405. Epub 2017 Mar 14 doi: 10.1177/0269881117695879. PMID: 28347257
Lehmann LS
Am J Psychiatry 1974 Nov;131(11):1221-4. doi: 10.1176/ajp.131.11.1221. PMID: 4424036

Prognosis

Long J, Hull R
Philos Ethics Humanit Med 2023 Nov 8;18(1):14. doi: 10.1186/s13010-023-00142-8. PMID: 37936219Free PMC Article
Attademo L, Bernardini F
CNS Spectr 2021 Oct;26(5):468-480. Epub 2020 Jul 27 doi: 10.1017/S1092852920001716. PMID: 32713392
Apthorp D, Bolbecker AR, Bartolomeo LA, O'Donnell BF, Hetrick WP
Schizophr Bull 2019 Apr 25;45(3):512-521. doi: 10.1093/schbul/sby141. PMID: 30376125Free PMC Article
Abu-Akel A, Clark J, Perry A, Wood SJ, Forty L, Craddock N, Jones I, Gordon-Smith K, Jones L
J Affect Disord 2017 Jan 1;207:268-275. Epub 2016 Oct 3 doi: 10.1016/j.jad.2016.09.059. PMID: 27736738
Häfner H, an der Heiden W
Can J Psychiatry 1997 Mar;42(2):139-51. doi: 10.1177/070674379704200204. PMID: 9067063

Clinical prediction guides

Nenadić I, Meller T, Schmitt S, Stein F, Brosch K, Mosebach J, Ettinger U, Grant P, Meinert S, Opel N, Lemke H, Fingas S, Förster K, Hahn T, Jansen A, Andlauer TFM, Forstner AJ, Heilmann-Heimbach S, Hall ASM, Awasthi S, Ripke S, Witt SH, Rietschel M, Müller-Myhsok B, Nöthen MM, Dannlowski U, Krug A, Streit F, Kircher T
Psychol Med 2022 Apr;52(6):1069-1079. Epub 2020 Aug 6 doi: 10.1017/S0033291720002822. PMID: 32758327
González-Rodríguez A, García-Pérez Á, Godoy-Giménez M, Carmona I, Estévez ÁF, Sayans-Jiménez P, Cañadas F
Sci Rep 2021 Nov 29;11(1):23048. doi: 10.1038/s41598-021-02336-6. PMID: 34845255Free PMC Article
de Francisco Carvalho L, Magarotto Machado G, Padovani S, Pianowski G
Scand J Psychol 2021 Dec;62(6):839-845. Epub 2021 Jul 9 doi: 10.1111/sjop.12761. PMID: 34245006
Liu J, Yang T, Zhou L, Gong J, He Y, Cui X, Luo X, Wu J
J Affect Disord 2021 Aug 1;291:83-92. Epub 2021 May 1 doi: 10.1016/j.jad.2021.04.079. PMID: 34023751
Attademo L, Bernardini F
CNS Spectr 2021 Oct;26(5):468-480. Epub 2020 Jul 27 doi: 10.1017/S1092852920001716. PMID: 32713392

Recent systematic reviews

Nielsen KD, Hovmand OR, Jørgensen MS, Meisner M, Arnfred SM
Clin Psychol Psychother 2023 Nov-Dec;30(6):1264-1278. Epub 2023 Sep 7 doi: 10.1002/cpp.2901. PMID: 37675964
Dong F, Liu J, Hodgson NA, Medoff-Cooper B
J Psychiatr Ment Health Nurs 2021 Dec;28(6):1092-1112. Epub 2021 Mar 15 doi: 10.1111/jpm.12733. PMID: 33502097
Attademo L, Bernardini F, Verdolini N
Curr Med Imaging 2021;17(11):1283-1298. doi: 10.2174/1573405617666210114142206. PMID: 33459241
Jakobsen KD, Skyum E, Hashemi N, Schjerning O, Fink-Jensen A, Nielsen J
J Psychopharmacol 2017 Apr;31(4):397-405. Epub 2017 Mar 14 doi: 10.1177/0269881117695879. PMID: 28347257
Fervaha G, Remington G
Prog Neuropsychopharmacol Biol Psychiatry 2013 Jun 3;43:96-107. Epub 2012 Dec 5 doi: 10.1016/j.pnpbp.2012.11.014. PMID: 23220094

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