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Somatoform disorder

MedGen UID:
20835
•Concept ID:
C0037650
•
Mental or Behavioral Dysfunction
Synonyms: Disorder, Somatoform; Medically Unexplained Syndrome; Medically Unexplained Syndromes; Somatoform Disorder; Somatoform Disorders; Syndrome, Medically Unexplained; Unexplained Syndrome, Medically
SNOMED CT: Psychosomatic disorder (31297008); Somatoform disorder (31297008)
 
Monarch Initiative: MONDO:0003117

Definition

A category of psychiatric disorders which are characterized by the presence of physical symptoms that suggest a medical condition but are not fully explained by any known medical reasons. [from NCI]

Professional guidelines

PubMed

Treatment of insomnia - effect of trazodone and hypnotics on sleep.
Wichniak A, Wierzbicka AE, Jarema M
Psychiatr Pol 2021 Aug 31;55(4):743-755. doi: 10.12740/PP/125650. PMID: 34994734
Psychogenic Pruritus and Its Management.
Buteau A, Reichenberg J
Dermatol Clin 2018 Jul;36(3):309-314. doi: 10.1016/j.det.2018.02.015. PMID: 29929602
Somatoform disorders and medically unexplained symptoms in primary care.
Haller H, Cramer H, Lauche R, Dobos G
Dtsch Arztebl Int 2015 Apr 17;112(16):279-87. doi: 10.3238/arztebl.2015.0279. PMID: 25939319Free PMC Article

Recent clinical studies

Etiology

A revised and extended systematic review and meta-analysis of the relationship between childhood adversity and adult psychiatric disorder.
McKay MT, Kilmartin L, Meagher A, Cannon M, Healy C, Clarke MC
J Psychiatr Res 2022 Dec;156:268-283. Epub 2022 Oct 10 doi: 10.1016/j.jpsychires.2022.10.015. PMID: 36274532
Do Limited English Proficiency and Language Moderate the Relationship Between Mental Health and Pain?
Koleck TA, Lor M
Pain Manag Nurs 2022 Aug;23(4):443-451. Epub 2021 Nov 22 doi: 10.1016/j.pmn.2021.10.005. PMID: 34824021Free PMC Article
Treatment of insomnia - effect of trazodone and hypnotics on sleep.
Wichniak A, Wierzbicka AE, Jarema M
Psychiatr Pol 2021 Aug 31;55(4):743-755. doi: 10.12740/PP/125650. PMID: 34994734
Self-compassion in somatoform disorder.
Dewsaran-van der Ven C, van Broeckhuysen-Kloth S, Thorsell S, Scholten R, De Gucht V, Geenen R
Psychiatry Res 2018 Apr;262:34-39. Epub 2017 Dec 9 doi: 10.1016/j.psychres.2017.12.013. PMID: 29407566
Somatoform disorders.
Oyama O, Paltoo C, Greengold J
Am Fam Physician 2007 Nov 1;76(9):1333-8. PMID: 18019877

Diagnosis

Somatic symptom disorder: a diagnostic dilemma.
Dunphy L, Penna M, El-Kafsi J
BMJ Case Rep 2019 Nov 25;12(11) doi: 10.1136/bcr-2019-231550. PMID: 31772129Free PMC Article
Idiopathic anaphylaxis.
Bilò MB, Martini M, Tontini C, Mohamed OE, Krishna MT
Clin Exp Allergy 2019 Jul;49(7):942-952. Epub 2019 May 13 doi: 10.1111/cea.13402. PMID: 31002196
Facts and myths pertaining to fibromyalgia.
Häuser W, Fitzcharles MA
Dialogues Clin Neurosci 2018 Mar;20(1):53-62. doi: 10.31887/DCNS.2018.20.1/whauser. PMID: 29946212Free PMC Article
Psychogenic Pruritus and Its Management.
Buteau A, Reichenberg J
Dermatol Clin 2018 Jul;36(3):309-314. doi: 10.1016/j.det.2018.02.015. PMID: 29929602
Somatoform disorders.
Oyama O, Paltoo C, Greengold J
Am Fam Physician 2007 Nov 1;76(9):1333-8. PMID: 18019877

Therapy

Treatment of insomnia - effect of trazodone and hypnotics on sleep.
Wichniak A, Wierzbicka AE, Jarema M
Psychiatr Pol 2021 Aug 31;55(4):743-755. doi: 10.12740/PP/125650. PMID: 34994734
Self-help interventions for young people with persistent physical symptoms: A systematic review.
Holsting AF, Rask MT, Frostholm L, Rosendal M, Rask CU
J Psychosom Res 2021 Sep;148:110553. Epub 2021 Jun 19 doi: 10.1016/j.jpsychores.2021.110553. PMID: 34242894
Somatoform disorders and medically unexplained symptoms in primary care.
Haller H, Cramer H, Lauche R, Dobos G
Dtsch Arztebl Int 2015 Apr 17;112(16):279-87. doi: 10.3238/arztebl.2015.0279. PMID: 25939319Free PMC Article
Pharmacological interventions for somatoform disorders in adults.
Kleinstäuber M, Witthöft M, Steffanowski A, van Marwijk H, Hiller W, Lambert MJ
Cochrane Database Syst Rev 2014 Nov 7;2014(11):CD010628. doi: 10.1002/14651858.CD010628.pub2. PMID: 25379990Free PMC Article
Somatoform disorders.
Oyama O, Paltoo C, Greengold J
Am Fam Physician 2007 Nov 1;76(9):1333-8. PMID: 18019877

Prognosis

Increased cardiovascular events in young patients with mental disorders: a nationwide cohort study.
Park CS, Choi EK, Han KD, Ahn HJ, Kwon S, Lee SR, Oh S, Lip GYH
Eur J Prev Cardiol 2023 Oct 26;30(15):1582-1592. doi: 10.1093/eurjpc/zwad102. PMID: 37156491
Treatment of insomnia - effect of trazodone and hypnotics on sleep.
Wichniak A, Wierzbicka AE, Jarema M
Psychiatr Pol 2021 Aug 31;55(4):743-755. doi: 10.12740/PP/125650. PMID: 34994734
Somatic symptom disorder: a diagnostic dilemma.
Dunphy L, Penna M, El-Kafsi J
BMJ Case Rep 2019 Nov 25;12(11) doi: 10.1136/bcr-2019-231550. PMID: 31772129Free PMC Article
Idiopathic anaphylaxis.
Bilò MB, Martini M, Tontini C, Mohamed OE, Krishna MT
Clin Exp Allergy 2019 Jul;49(7):942-952. Epub 2019 May 13 doi: 10.1111/cea.13402. PMID: 31002196
Validity of current somatoform disorder diagnoses: perspectives for classification in DSM-V and ICD-11.
Löwe B, Mundt C, Herzog W, Brunner R, Backenstrass M, Kronmüller K, Henningsen P
Psychopathology 2008;41(1):4-9. Epub 2007 Oct 18 doi: 10.1159/000109949. PMID: 17952015

Clinical prediction guides

Increased cardiovascular events in young patients with mental disorders: a nationwide cohort study.
Park CS, Choi EK, Han KD, Ahn HJ, Kwon S, Lee SR, Oh S, Lip GYH
Eur J Prev Cardiol 2023 Oct 26;30(15):1582-1592. doi: 10.1093/eurjpc/zwad102. PMID: 37156491
Do Limited English Proficiency and Language Moderate the Relationship Between Mental Health and Pain?
Koleck TA, Lor M
Pain Manag Nurs 2022 Aug;23(4):443-451. Epub 2021 Nov 22 doi: 10.1016/j.pmn.2021.10.005. PMID: 34824021Free PMC Article
Lying in neuropsychology.
Seron X
Neurophysiol Clin 2014 Oct;44(4):389-403. Epub 2014 May 6 doi: 10.1016/j.neucli.2014.04.002. PMID: 25306079
Is hypochondriasis an anxiety disorder?
Olatunji BO, Deacon BJ, Abramowitz JS
Br J Psychiatry 2009 Jun;194(6):481-2. doi: 10.1192/bjp.bp.108.061085. PMID: 19478284
Validity of current somatoform disorder diagnoses: perspectives for classification in DSM-V and ICD-11.
Löwe B, Mundt C, Herzog W, Brunner R, Backenstrass M, Kronmüller K, Henningsen P
Psychopathology 2008;41(1):4-9. Epub 2007 Oct 18 doi: 10.1159/000109949. PMID: 17952015

Recent systematic reviews

A revised and extended systematic review and meta-analysis of the relationship between childhood adversity and adult psychiatric disorder.
McKay MT, Kilmartin L, Meagher A, Cannon M, Healy C, Clarke MC
J Psychiatr Res 2022 Dec;156:268-283. Epub 2022 Oct 10 doi: 10.1016/j.jpsychires.2022.10.015. PMID: 36274532
Structural neuroimaging of somatoform disorders: A systematic review.
Rossetti MG, Delvecchio G, Calati R, Perlini C, Bellani M, Brambilla P
Neurosci Biobehav Rev 2021 Mar;122:66-78. Epub 2020 Dec 20 doi: 10.1016/j.neubiorev.2020.12.017. PMID: 33359097
Vagus nerve stimulation in psychiatry: a systematic review of the available evidence.
Cimpianu CL, Strube W, Falkai P, Palm U, Hasan A
J Neural Transm (Vienna) 2017 Jan;124(1):145-158. Epub 2016 Nov 16 doi: 10.1007/s00702-016-1642-2. PMID: 27848034
Pharmacological interventions for somatoform disorders in adults.
Kleinstäuber M, Witthöft M, Steffanowski A, van Marwijk H, Hiller W, Lambert MJ
Cochrane Database Syst Rev 2014 Nov 7;2014(11):CD010628. doi: 10.1002/14651858.CD010628.pub2. PMID: 25379990Free PMC Article
Towards positive diagnostic criteria: a systematic review of somatoform disorder diagnoses and suggestions for future classification.
Voigt K, Nagel A, Meyer B, Langs G, Braukhaus C, Löwe B
J Psychosom Res 2010 May;68(5):403-14. Epub 2010 Mar 12 doi: 10.1016/j.jpsychores.2010.01.015. PMID: 20403499

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