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Unresectable Cholangiocarcinoma

MedGen UID:
209022
Concept ID:
C0862953
Neoplastic Process
Synonym: Non-Resectable Cholangiocarcinoma

Definition

Cholangiocarcinoma that is not amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Cholangiocarcinoma

Professional guidelines

PubMed

Ohaegbulam KC, Koethe Y, Fung A, Mayo SC, Grossberg AJ, Chen EY, Sharzehi K, Kardosh A, Farsad K, Rocha FG, Thomas CR, Nabavizadeh N
Cancer 2023 Jan 15;129(2):184-214. Epub 2022 Nov 16 doi: 10.1002/cncr.34541. PMID: 36382577
Najran P, Lamarca A, Mullan D, McNamara MG, Westwood T, Hubner RA, Lawrence J, Manoharan P, Bell J, Valle JW
Curr Oncol Rep 2017 Jul;19(7):50. doi: 10.1007/s11912-017-0603-8. PMID: 28656502Free PMC Article
Talreja JP, DeGaetani M, Sauer BG, Kahaleh M
Photochem Photobiol Sci 2011 Jul;10(7):1233-8. Epub 2011 Apr 21 doi: 10.1039/c0pp00259c. PMID: 21512706

Recent clinical studies

Etiology

Mohan BP, Chandan S, Khan SR, Kassab LL, Ponnada S, Artifon ELA, Otoch JP, McDonough S, Adler DG
J Clin Gastroenterol 2022 Feb 1;56(2):e153-e160. doi: 10.1097/MCG.0000000000001524. PMID: 33780214
Pietge H, Sánchez-Velázquez P, Akhoundova D, Siebenhüner A, Winder T, Bachmann H, Nguyen-Kim TDL, Breitenstein S, Knuth A, Petrowsky H, Pestalozzi B, Clavien PA, Samaras P
Oncology 2021;99(5):300-309. Epub 2021 Mar 3 doi: 10.1159/000512967. PMID: 33657549Free PMC Article
Massani M, Nistri C, Ruffolo C, Bonariol R, Pauletti B, Bonariol L, Caratozzolo E, Morana G, Bassi N
Updates Surg 2015 Dec;67(4):389-400. doi: 10.1007/s13304-015-0330-3. PMID: 26468142
Lu Y, Liu L, Wu JC, Bie LK, Gong B
Clin Res Hepatol Gastroenterol 2015 Dec;39(6):718-24. Epub 2015 Jun 10 doi: 10.1016/j.clinre.2014.10.015. PMID: 26070572
Abu-Hamda EM, Baron TH
Semin Liver Dis 2004 May;24(2):165-75. doi: 10.1055/s-2004-828893. PMID: 15192789

Diagnosis

Han Y, Yang Y, Huang S, Yao L, Wu L
Biochem Biophys Res Commun 2022 Feb 5;591:54-61. Epub 2021 Dec 21 doi: 10.1016/j.bbrc.2021.12.070. PMID: 34999254
Belfiore MP, Reginelli A, Maggialetti N, Carbone M, Giovine S, Laporta A, Urraro F, Nardone V, Grassi R, Cappabianca S, Brunese L
Med Oncol 2020 Apr 9;37(5):45. doi: 10.1007/s12032-020-01360-2. PMID: 32270353
Brandi G, Venturi M, Pantaleo MA, Ercolani G; GICO
Dig Liver Dis 2016 Mar;48(3):231-41. Epub 2015 Nov 28 doi: 10.1016/j.dld.2015.11.017. PMID: 26769568
Tomizawa Y, Tian J
Dig Dis Sci 2012 Feb;57(2):274-83. Epub 2011 Nov 6 doi: 10.1007/s10620-011-1957-7. PMID: 22057285
Abu-Hamda EM, Baron TH
Semin Liver Dis 2004 May;24(2):165-75. doi: 10.1055/s-2004-828893. PMID: 15192789

Therapy

Beri N
Immunotherapy 2023 May;15(7):541-551. Epub 2023 Apr 25 doi: 10.2217/imt-2022-0288. PMID: 37096964
Massani M, Nistri C, Ruffolo C, Bonariol R, Pauletti B, Bonariol L, Caratozzolo E, Morana G, Bassi N
Updates Surg 2015 Dec;67(4):389-400. doi: 10.1007/s13304-015-0330-3. PMID: 26468142
Leggett CL, Gorospe EC, Murad MH, Montori VM, Baron TH, Wang KK
Photodiagnosis Photodyn Ther 2012 Sep;9(3):189-95. Epub 2012 Apr 11 doi: 10.1016/j.pdpdt.2012.03.002. PMID: 22959798
Gao F, Bai Y, Ma SR, Liu F, Li ZS
J Hepatobiliary Pancreat Sci 2010 Mar;17(2):125-31. Epub 2009 May 20 doi: 10.1007/s00534-009-0109-3. PMID: 19455276
Yeo CJ, Pitt HA, Cameron JL
Surg Clin North Am 1990 Dec;70(6):1429-47. doi: 10.1016/s0039-6109(16)45293-x. PMID: 2174191

Prognosis

Beri N
Immunotherapy 2023 May;15(7):541-551. Epub 2023 Apr 25 doi: 10.2217/imt-2022-0288. PMID: 37096964
Lu Y, Liu L, Wu JC, Bie LK, Gong B
Clin Res Hepatol Gastroenterol 2015 Dec;39(6):718-24. Epub 2015 Jun 10 doi: 10.1016/j.clinre.2014.10.015. PMID: 26070572
Kuhlmann JB, Blum HE
Curr Opin Gastroenterol 2013 May;29(3):324-8. doi: 10.1097/MOG.0b013e32835d9dea. PMID: 23337933
Tomizawa Y, Tian J
Dig Dis Sci 2012 Feb;57(2):274-83. Epub 2011 Nov 6 doi: 10.1007/s10620-011-1957-7. PMID: 22057285
Abu-Hamda EM, Baron TH
Semin Liver Dis 2004 May;24(2):165-75. doi: 10.1055/s-2004-828893. PMID: 15192789

Clinical prediction guides

Beri N
Immunotherapy 2023 May;15(7):541-551. Epub 2023 Apr 25 doi: 10.2217/imt-2022-0288. PMID: 37096964
Belfiore MP, Reginelli A, Maggialetti N, Carbone M, Giovine S, Laporta A, Urraro F, Nardone V, Grassi R, Cappabianca S, Brunese L
Med Oncol 2020 Apr 9;37(5):45. doi: 10.1007/s12032-020-01360-2. PMID: 32270353
Hung SP, Huang BS, Hsieh CE, Lee CH, Tsang NM, Chang JT, Chen JS, Chou WC, Tseng JH, Hong JH
Am J Clin Oncol 2020 Mar;43(3):180-186. doi: 10.1097/COC.0000000000000646. PMID: 31764017
Yang LC, Shi HY, Huang JW, Lee KT
Kaohsiung J Med Sci 2015 Jul;31(7):370-6. Epub 2015 Jun 10 doi: 10.1016/j.kjms.2015.05.001. PMID: 26162818
Leggett CL, Gorospe EC, Murad MH, Montori VM, Baron TH, Wang KK
Photodiagnosis Photodyn Ther 2012 Sep;9(3):189-95. Epub 2012 Apr 11 doi: 10.1016/j.pdpdt.2012.03.002. PMID: 22959798

Recent systematic reviews

Mohan BP, Chandan S, Khan SR, Kassab LL, Ponnada S, Artifon ELA, Otoch JP, McDonough S, Adler DG
J Clin Gastroenterol 2022 Feb 1;56(2):e153-e160. doi: 10.1097/MCG.0000000000001524. PMID: 33780214
Moole H, Tathireddy H, Dharmapuri S, Moole V, Boddireddy R, Yedama P, Dharmapuri S, Uppu A, Bondalapati N, Duvvuri A
World J Gastroenterol 2017 Feb 21;23(7):1278-1288. doi: 10.3748/wjg.v23.i7.1278. PMID: 28275308Free PMC Article
Mattiucci GC, Autorino R, D'Agostino GR, Deodato F, Macchia G, Perri V, Tringali A, Morganti AG, Mutignani M, Valentini V
Crit Rev Oncol Hematol 2014 Apr;90(1):58-67. Epub 2013 Nov 2 doi: 10.1016/j.critrevonc.2013.10.007. PMID: 24289902
Leggett CL, Gorospe EC, Murad MH, Montori VM, Baron TH, Wang KK
Photodiagnosis Photodyn Ther 2012 Sep;9(3):189-95. Epub 2012 Apr 11 doi: 10.1016/j.pdpdt.2012.03.002. PMID: 22959798
Gao F, Bai Y, Ma SR, Liu F, Li ZS
J Hepatobiliary Pancreat Sci 2010 Mar;17(2):125-31. Epub 2009 May 20 doi: 10.1007/s00534-009-0109-3. PMID: 19455276

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