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Temporomandibular joint dysfunction syndrome

MedGen UID:
21093
Concept ID:
C0039496
Disease or Syndrome
Synonyms: Costen Syndrome; Costen's Syndrome; Costens Syndrome; Joint Syndrome, Temporomandibular; Myofascial Pain Dysfunction Syndrome, Temporomandibular Joint; Syndrome, Costen's; Syndrome, Temporomandibular Joint; Syndrome, TMJ; Temporomandibular Joint Dysfunction Syndrome; Temporomandibular Joint Syndrome; TMJ Syndrome
SNOMED CT: Temporomandibular joint-pain-dysfunction syndrome (386207004); TMJ syndrome (386207004); Costen's syndrome (386207004); Mandibular dysfunction (386207004); Costen's complex (386207004); Temporomandibular joint pain dysfunction syndrome (386207004); Snapping jaw (386207004); TMJPDS - Temporomandibular joint pain dysfunction syndrome (386207004); Myofascial pain - dysfunction syndrome of TMJ (386207004); Temporomandibular joint syndrome (41888000)
 
Monarch Initiative: MONDO:0021895

Definition

A common disorder noted with jaw movement. It may be caused by malocclusion, repetitive use injury, trauma or arthritis. It is more prevalent among females between their second and fourth decades. Clinical signs include preauricular pain, temporomandibular joint clicking (as the mandibular condyle slips from the articulation made with the capsular disc and temporal bone) and restriction of jaw motion. Clinical course is typically benign but may progress to associated headaches, ear and neck pain, tinnitus and dislocation of temporomandibular joint. Prognosis is favorable as a majority of cases will respond to conservative management. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTemporomandibular joint dysfunction syndrome

Professional guidelines

PubMed

Tran C, Ghahreman K, Huppa C, Gallagher JE
Int J Oral Maxillofac Surg 2022 Sep;51(9):1211-1225. Epub 2022 Mar 23 doi: 10.1016/j.ijom.2021.11.009. PMID: 35339331
Asquini G, Rushton A, Pitance L, Heneghan N, Falla D
Syst Rev 2021 Mar 8;10(1):70. doi: 10.1186/s13643-021-01623-7. PMID: 33685496Free PMC Article
Häggman-Henrikson B, Alstergren P, Davidson T, Högestätt ED, Östlund P, Tranaeus S, Vitols S, List T
J Oral Rehabil 2017 Oct;44(10):800-826. Epub 2017 Jul 29 doi: 10.1111/joor.12539. PMID: 28884860

Recent clinical studies

Etiology

Brandão RAFS, Mendes CMC, Brandão Filho RA, De Sena EP
Cranio 2022 May;40(3):199-206. Epub 2020 Jan 3 doi: 10.1080/08869634.2019.1708607. PMID: 31900091
Urbani G, Cozendey-Silva EN, Jesus LF
Cien Saude Colet 2019 May 30;24(5):1753-1765. doi: 10.1590/1413-81232018245.16162017. PMID: 31166510
Dursun Ö, Çankaya T
J Stroke Cerebrovasc Dis 2018 Aug;27(8):2141-2146. Epub 2018 Apr 9 doi: 10.1016/j.jstrokecerebrovasdis.2018.03.007. PMID: 29650380
Effat KG
J Laryngol Otol 2016 Dec;130(12):1137-1141. doi: 10.1017/S0022215116009300. PMID: 27938466
DuPont JS Jr, Brown CE
Cranio 2009 Jul;27(3):180-4. doi: 10.1179/crn.2009.027. PMID: 19697646

Diagnosis

Lomas J, Gurgenci T, Jackson C, Campbell D
Aust J Gen Pract 2018 Apr;47(4):212-215. doi: 10.31128/AFP-10-17-4375. PMID: 29621862
Fernández-de-las-Penas C, Svensson P
Curr Rheumatol Rev 2016;12(1):40-54. doi: 10.2174/1573397112666151231110947. PMID: 26717949
Miernik M, Wieckiewicz M, Paradowska A, Wieckiewicz W
Adv Clin Exp Med 2012 Sep-Oct;21(5):681-5. PMID: 23356206
Kim DS, Cheang P, Dover S, Drake-Lee AB
J Laryngol Otol 2007 Dec;121(12):1129-34. Epub 2007 Aug 21 doi: 10.1017/S0022215107000333. PMID: 17708777
Solberg WK
Semin Neurol 1988 Dec;8(4):291-7. doi: 10.1055/s-2008-1041392. PMID: 3074424

Therapy

Brandão RAFS, Mendes CMC, Lopes TDS, Brandão Filho RA, Sena EP
Codas 2021;33(3):e20190218. Epub 2021 May 14 doi: 10.1590/2317-1782/20202019218. PMID: 34008769
Kaya DI, Ataoglu H
Niger J Clin Pract 2021 Mar;24(3):412-417. doi: 10.4103/njcp.njcp_251_20. PMID: 33723117
Pihut M, Ferendiuk E, Szewczyk M, Kasprzyk K, Wieckiewicz M
J Headache Pain 2016;17:29. Epub 2016 Mar 24 doi: 10.1186/s10194-016-0621-1. PMID: 27011213Free PMC Article
Agostino P, Ugolini A, Signori A, Silvestrini-Biavati A, Harrison JE, Riley P
Cochrane Database Syst Rev 2014 Aug 8;(8):CD000979. doi: 10.1002/14651858.CD000979.pub2. PMID: 25104166
Craane B, Dijkstra PU, Stappaerts K, De Laat A
J Dent Res 2012 Apr;91(4):364-9. Epub 2012 Feb 8 doi: 10.1177/0022034512438275. PMID: 22318373

Prognosis

Manfredini D, Castroflorio T, Perinetti G, Guarda-Nardini L
J Oral Rehabil 2012 Jun;39(6):463-71. Epub 2012 Mar 21 doi: 10.1111/j.1365-2842.2012.02291.x. PMID: 22435603
Craane B, Dijkstra PU, Stappaerts K, De Laat A
J Dent Res 2012 Apr;91(4):364-9. Epub 2012 Feb 8 doi: 10.1177/0022034512438275. PMID: 22318373
Okeson JP
Tex Dent J 2000 Jul;117(7):64-74. PMID: 11858065
Von Korff M, Ormel J, Keefe FJ, Dworkin SF
Pain 1992 Aug;50(2):133-149. doi: 10.1016/0304-3959(92)90154-4. PMID: 1408309
Wazen JJ
Otolaryngol Clin North Am 1989 Dec;22(6):1205-15. PMID: 2689964

Clinical prediction guides

Brandão RAFS, Mendes CMC, Lopes TDS, Brandão Filho RA, Sena EP
Codas 2021;33(3):e20190218. Epub 2021 May 14 doi: 10.1590/2317-1782/20202019218. PMID: 34008769
Kaya DI, Ataoglu H
Niger J Clin Pract 2021 Mar;24(3):412-417. doi: 10.4103/njcp.njcp_251_20. PMID: 33723117
Braz MA, Freitas Portella F, Seehaber KA, Bavaresco CS, Rivaldo EG
J Oral Rehabil 2020 Apr;47(4):536-546. Epub 2020 Jan 16 doi: 10.1111/joor.12930. PMID: 31880832
Fernandes AC, Duarte Moura DM, Da Silva LGD, De Almeida EO, Barbosa GAS
J Oral Facial Pain Headache 2017 Summer;31(3):225-232. doi: 10.11607/ofph.1719. PMID: 28738107
Manfredini D, Castroflorio T, Perinetti G, Guarda-Nardini L
J Oral Rehabil 2012 Jun;39(6):463-71. Epub 2012 Mar 21 doi: 10.1111/j.1365-2842.2012.02291.x. PMID: 22435603

Recent systematic reviews

Almășan O, Hedeșiu M, Băciuț M, Buduru S, Dinu C
J Oral Rehabil 2023 Mar;50(3):243-255. Epub 2023 Jan 12 doi: 10.1111/joor.13409. PMID: 36582136
Fernandes AC, Duarte Moura DM, Da Silva LGD, De Almeida EO, Barbosa GAS
J Oral Facial Pain Headache 2017 Summer;31(3):225-232. doi: 10.11607/ofph.1719. PMID: 28738107
Jiménez-Silva A, Peña-Durán C, Tobar-Reyes J, Frugone-Zambra R
Acta Odontol Scand 2017 Jan;75(1):36-58. Epub 2016 Oct 31 doi: 10.1080/00016357.2016.1247465. PMID: 27796166
Fernández-de-las-Penas C, Svensson P
Curr Rheumatol Rev 2016;12(1):40-54. doi: 10.2174/1573397112666151231110947. PMID: 26717949
Agostino P, Ugolini A, Signori A, Silvestrini-Biavati A, Harrison JE, Riley P
Cochrane Database Syst Rev 2014 Aug 8;(8):CD000979. doi: 10.1002/14651858.CD000979.pub2. PMID: 25104166

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