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Teratoma

MedGen UID:
21097
Concept ID:
C0039538
Neoplastic Process
Synonyms: Dysembryoma; Dysembryomas; Teratoid Tumor; Teratoid Tumors; Teratomas; Tumor, Teratoid; Tumors, Teratoid
SNOMED CT: Teratoma (36591000119102); Teratoma (1187393008)
 
HPO: HP:0009792
Monarch Initiative: MONDO:0002601

Definition

The presence of a teratoma. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Teratoma
Follow this link to review classifications for Teratoma in Orphanet.

Conditions with this feature

Aicardi syndrome
MedGen UID:
61236
Concept ID:
C0175713
Disease or Syndrome
Aicardi syndrome is a neurodevelopmental disorder that affects primarily females. Initially it was characterized by a typical triad of agenesis of the corpus callosum, central chorioretinal lacunae, and infantile spasms. As more affected individuals have been ascertained, it has become clear that not all affected girls have all three features of the classic triad and that other neurologic and systemic defects are common, including other brain malformations, optic nerve abnormalities, other seizure types, intellectual disability of varying severity, and scoliosis.
Schinzel-Giedion syndrome
MedGen UID:
120517
Concept ID:
C0265227
Disease or Syndrome
Schinzel-Giedion syndrome is a highly recognizable syndrome characterized by severe mental retardation, distinctive facial features, and multiple congenital malformations including skeletal abnormalities, genitourinary and renal malformations, and cardiac defects, as well as a higher-than-normal prevalence of tumors, notably neuroepithelial neoplasia (summary by Hoischen et al., 2010).
Germ cell tumor of testis
MedGen UID:
277809
Concept ID:
C1336708
Neoplastic Process
Testicular germ cell tumors (TGCTs) affect 1 in 500 men and are the most common cancer in males aged 15 to 40 in western European populations. The incidence of TGCT rose dramatically during the 20th century. Known risk factors for TGCT include a history of undescended testis (UDT), testicular dysgenesis, infertility, previously diagnosed TGCT, and a family history of the disease. Brothers of men with TGCT have an 8- to 10-fold risk of developing TGCT, whereas the relative risk to fathers and sons is 4-fold. This familial relative risk is much higher than that for most other types of cancer (summary by Rapley et al., 2000). Genetic Heterogeneity of Testicular Germ Cell Tumors A locus for testicular germ cell tumors (TGCT1; 300228) has been identified on chromosome Xq27.
Teratoma, pineal
MedGen UID:
336449
Concept ID:
C1848902
Neoplastic Process

Professional guidelines

PubMed

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Blood 2024 Oct 3;144(14):1486-1495. doi: 10.1182/blood.2023023780. PMID: 38838300
Saleh M, Bhosale P, Menias CO, Ramalingam P, Jensen C, Iyer R, Ganeshan D
Abdom Radiol (NY) 2021 Jun;46(6):2293-2307. Epub 2021 Jan 4 doi: 10.1007/s00261-020-02873-0. PMID: 33394097
Gresa-Arribas N, Titulaer MJ, Torrents A, Aguilar E, McCracken L, Leypoldt F, Gleichman AJ, Balice-Gordon R, Rosenfeld MR, Lynch D, Graus F, Dalmau J
Lancet Neurol 2014 Feb;13(2):167-77. Epub 2013 Dec 18 doi: 10.1016/S1474-4422(13)70282-5. PMID: 24360484Free PMC Article

Recent clinical studies

Therapy

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J Clin Oncol 2020 Apr 10;38(11):1175-1185. Epub 2020 Feb 27 doi: 10.1200/JCO.19.01776. PMID: 32105509Free PMC Article
Dalmau J, Lancaster E, Martinez-Hernandez E, Rosenfeld MR, Balice-Gordon R
Lancet Neurol 2011 Jan;10(1):63-74. doi: 10.1016/S1474-4422(10)70253-2. PMID: 21163445Free PMC Article
Dalmau J, Tüzün E, Wu HY, Masjuan J, Rossi JE, Voloschin A, Baehring JM, Shimazaki H, Koide R, King D, Mason W, Sansing LH, Dichter MA, Rosenfeld MR, Lynch DR
Ann Neurol 2007 Jan;61(1):25-36. doi: 10.1002/ana.21050. PMID: 17262855Free PMC Article
Paulson DF
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Peckham MJ, McElwain TJ
Clin Endocrinol Metab 1975 Nov;4(3):665-92. doi: 10.1016/s0300-595x(75)80052-1. PMID: 58746

Prognosis

Li S, Hong R, Yin M, Zhang T, Zhang X, Yang J
BMC Womens Health 2023 Sep 19;23(1):497. doi: 10.1186/s12905-023-02624-5. PMID: 37726744Free PMC Article
Isaacs H Jr
Pediatr Cardiol 2004 May-Jun;25(3):252-73. doi: 10.1007/s00246-003-0590-4. PMID: 15360117
Srinivasan US, Joseph T
Pediatr Neurosurg 1999 Apr;30(4):200-2. doi: 10.1159/000028795. PMID: 10420130
Ohaegbulam SC
Neurol Res 1999 Mar;21(2):161-70. doi: 10.1080/01616412.1999.11740912. PMID: 10100202
Forman D, Møller H
Cancer Surv 1994;19-20:323-41. PMID: 7534631

Clinical prediction guides

Atwi D, Kamal M, Quinton M, Hassell LA
J Obstet Gynaecol Res 2022 Dec;48(12):3068-3076. Epub 2022 Sep 2 doi: 10.1111/jog.15409. PMID: 36053141
Heremans R, Valentin L, Sladkevicius P, Timmerman S, Moro F, Van Holsbeke C, Epstein E, Testa AC, Timmerman D, Froyman W
Ultrasound Obstet Gynecol 2022 Oct;60(4):549-558. Epub 2022 Sep 15 doi: 10.1002/uog.24904. PMID: 35316568
Michalski W, Jonska-Gmyrek J, Poniatowska G, Kucharz J, Stelmasiak P, Nietupski K, Sadowska M, Demkow T, Wiechno P
Med Oncol 2018 Oct 26;35(12):153. doi: 10.1007/s12032-018-1215-3. PMID: 30367327
Jose de Carli G, Campos Pereira T
Med Hypotheses 2017 Sep;106:57-60. Epub 2017 Jul 11 doi: 10.1016/j.mehy.2017.07.008. PMID: 28818272
Nielsen SN, Scheithauer BW, Gaffey TA
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Recent systematic reviews

Vasilevska V, Guest PC, Szardenings M, Benros ME, Steiner J
Transl Psychiatry 2024 Mar 8;14(1):139. doi: 10.1038/s41398-024-02831-0. PMID: 38459000Free PMC Article
Wilpers A, Lynn AY, Eichhorn B, Powne AB, Lagueux M, Batten J, Bahtiyar MO, Gross CP
Fetal Diagn Ther 2022;49(3):125-137. Epub 2022 Mar 10 doi: 10.1159/000523867. PMID: 35272297Free PMC Article
Eisenberg N, Volodarsky-Perel A, Brochu I, Tremblay C, Gorak E, Hudon E, Fortin S, Kogan L, Rivard C
J Minim Invasive Gynecol 2021 May;28(5):957-970. Epub 2020 Dec 3 doi: 10.1016/j.jmig.2020.11.025. PMID: 33279627
Wang L, Li T, Gong M, Xing F, Li L, Xiao R, Guan Q
Medicine (Baltimore) 2020 May;99(18):e20107. doi: 10.1097/MD.0000000000020107. PMID: 32358400Free PMC Article
Tzani A, Doulamis IP, Mylonas KS, Avgerinos DV, Nasioudis D
World J Pediatr Congenit Heart Surg 2017 Sep;8(5):624-632. doi: 10.1177/2150135117723904. PMID: 28901236

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