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Traumatic hemorrhage

MedGen UID:
21247
•Concept ID:
C0040797
•
Pathologic Function
Synonym: Traumatic Hemorrhage
SNOMED CT: Traumatic hemorrhage (110149000)

Definition

Vascular rupture, and the resulting loss of blood, due to physical injury. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTraumatic hemorrhage

Professional guidelines

PubMed

Guidelines for the Acute Treatment of Cerebral Edema in Neurocritical Care Patients.
Cook AM, Morgan Jones G, Hawryluk GWJ, Mailloux P, McLaughlin D, Papangelou A, Samuel S, Tokumaru S, Venkatasubramanian C, Zacko C, Zimmermann LL, Hirsch K, Shutter L
Neurocrit Care 2020 Jun;32(3):647-666. doi: 10.1007/s12028-020-00959-7. PMID: 32227294Free PMC Article
The Diagnosis and Treatment of Acute Traumatic Bleeding and Coagulopathy.
Maegele M
Dtsch Arztebl Int 2019 Nov 22;116(47):799-806. doi: 10.3238/arztebl.2019.0799. PMID: 31847951Free PMC Article
Platelet transfusion: a clinical practice guideline from the AABB.
Kaufman RM, Djulbegovic B, Gernsheimer T, Kleinman S, Tinmouth AT, Capocelli KE, Cipolle MD, Cohn CS, Fung MK, Grossman BJ, Mintz PD, O'Malley BA, Sesok-Pizzini DA, Shander A, Stack GE, Webert KE, Weinstein R, Welch BG, Whitman GJ, Wong EC, Tobian AA; AABB
Ann Intern Med 2015 Feb 3;162(3):205-13. doi: 10.7326/M14-1589. PMID: 25383671

Recent clinical studies

Etiology

Myocardial alterations following traumatic hemorrhagic injury.
Simpson R, Praditsuktavorn B, Wall J, Morales V, Thiemermann C, Tremoleda JL, Brohi K
J Trauma Acute Care Surg 2023 Oct 1;95(4):481-489. Epub 2023 May 29 doi: 10.1097/TA.0000000000003987. PMID: 37249511
Whole blood transfusion in the treatment of acute hemorrhage, a systematic review and meta-analysis.
van der Horst RA, Rijnhout TWH, Noorman F, Borger van der Burg BLS, van Waes OJF, Verhofstad MHJ, Hoencamp R
J Trauma Acute Care Surg 2023 Aug 1;95(2):256-266. Epub 2023 May 1 doi: 10.1097/TA.0000000000004000. PMID: 37125904
Efficacy and Safety of Early Administration of 4-Factor Prothrombin Complex Concentrate in Patients With Trauma at Risk of Massive Transfusion: The PROCOAG Randomized Clinical Trial.
Bouzat P, Charbit J, Abback PS, Huet-Garrigue D, Delhaye N, Leone M, Marcotte G, David JS, Levrat A, Asehnoune K, Pottecher J, Duranteau J, Courvalin E, Adolle A, Sourd D, Bosson JL, Riou B, Gauss T, Payen JF; PROCOAG Study Group
JAMA 2023 Apr 25;329(16):1367-1375. doi: 10.1001/jama.2023.4080. PMID: 36942533Free PMC Article
Artificial intelligence and machine learning for hemorrhagic trauma care.
Peng HT, Siddiqui MM, Rhind SG, Zhang J, da Luz LT, Beckett A
Mil Med Res 2023 Feb 16;10(1):6. doi: 10.1186/s40779-023-00444-0. PMID: 36793066Free PMC Article
Whole Blood Transfusion.
Cap AP, Beckett A, Benov A, Borgman M, Chen J, Corley JB, Doughty H, Fisher A, Glassberg E, Gonzales R, Kane SF, Malloy WW, Nessen S, Perkins JG, Prat N, Quesada J, Reade M, Sailliol A, Spinella PC, Stockinger Z, Strandenes G, Taylor A, Yazer M, Bryant B, Gurney J
Mil Med 2018 Sep 1;183(suppl_2):44-51. doi: 10.1093/milmed/usy120. PMID: 30189061

Diagnosis

Massive transfusion in trauma.
Lier H, Hossfeld B
Curr Opin Anaesthesiol 2024 Apr 1;37(2):117-124. Epub 2024 Jan 19 doi: 10.1097/ACO.0000000000001347. PMID: 38390985
Traumatic hemorrhage and chain of survival.
Latif RK, Clifford SP, Baker JA, Lenhardt R, Haq MZ, Huang J, Farah I, Businger JR
Scand J Trauma Resusc Emerg Med 2023 May 24;31(1):25. doi: 10.1186/s13049-023-01088-8. PMID: 37226264Free PMC Article
Massive Hemorrhage Protocol: A Practical Approach to the Bleeding Trauma Patient.
Petrosoniak A, Pavenski K, da Luz LT, Callum J
Emerg Med Clin North Am 2023 Feb;41(1):51-69. doi: 10.1016/j.emc.2022.09.010. PMID: 36424044
Femoral vascular access for endovascular resuscitation.
Manning JE, Moore EE, Morrison JJ, Lyon RF, DuBose JJ, Ross JD
J Trauma Acute Care Surg 2021 Oct 1;91(4):e104-e113. doi: 10.1097/TA.0000000000003339. PMID: 34238862
The Diagnosis and Treatment of Acute Traumatic Bleeding and Coagulopathy.
Maegele M
Dtsch Arztebl Int 2019 Nov 22;116(47):799-806. doi: 10.3238/arztebl.2019.0799. PMID: 31847951Free PMC Article

Therapy

Massive transfusion in trauma.
Lier H, Hossfeld B
Curr Opin Anaesthesiol 2024 Apr 1;37(2):117-124. Epub 2024 Jan 19 doi: 10.1097/ACO.0000000000001347. PMID: 38390985
Emergent vessel embolization for major traumatic and non-traumatic hemorrhage: Indications, tools and outcomes.
Hörer TM, Ierardi AM, Carriero S, Lanza C, Carrafiello G, McGreevy DT
Semin Vasc Surg 2023 Jun;36(2):283-299. Epub 2023 May 1 doi: 10.1053/j.semvascsurg.2023.04.011. PMID: 37330241
Whole blood transfusion in the treatment of acute hemorrhage, a systematic review and meta-analysis.
van der Horst RA, Rijnhout TWH, Noorman F, Borger van der Burg BLS, van Waes OJF, Verhofstad MHJ, Hoencamp R
J Trauma Acute Care Surg 2023 Aug 1;95(2):256-266. Epub 2023 May 1 doi: 10.1097/TA.0000000000004000. PMID: 37125904
Efficacy and Safety of Early Administration of 4-Factor Prothrombin Complex Concentrate in Patients With Trauma at Risk of Massive Transfusion: The PROCOAG Randomized Clinical Trial.
Bouzat P, Charbit J, Abback PS, Huet-Garrigue D, Delhaye N, Leone M, Marcotte G, David JS, Levrat A, Asehnoune K, Pottecher J, Duranteau J, Courvalin E, Adolle A, Sourd D, Bosson JL, Riou B, Gauss T, Payen JF; PROCOAG Study Group
JAMA 2023 Apr 25;329(16):1367-1375. doi: 10.1001/jama.2023.4080. PMID: 36942533Free PMC Article
Blood Product Transfusions and Reactions.
Osterman JL, Arora S
Hematol Oncol Clin North Am 2017 Dec;31(6):1159-1170. doi: 10.1016/j.hoc.2017.08.014. PMID: 29078929

Prognosis

Artificial intelligence and machine learning for hemorrhagic trauma care.
Peng HT, Siddiqui MM, Rhind SG, Zhang J, da Luz LT, Beckett A
Mil Med Res 2023 Feb 16;10(1):6. doi: 10.1186/s40779-023-00444-0. PMID: 36793066Free PMC Article
The extended autonomic system, dyshomeostasis, and COVID-19.
Goldstein DS
Clin Auton Res 2020 Aug;30(4):299-315. Epub 2020 Jul 22 doi: 10.1007/s10286-020-00714-0. PMID: 32700055Free PMC Article
Pediatric Massive Transfusion: A Systematic Review.
Maw G, Furyk C
Pediatr Emerg Care 2018 Aug;34(8):594-598. doi: 10.1097/PEC.0000000000001570. PMID: 30080793
Tourniquets in Trauma Care: A Review of Application.
Cornelius B, Campbell R, McGauly P
J Trauma Nurs 2017 May/Jun;24(3):203-207. doi: 10.1097/JTN.0000000000000290. PMID: 28486327
Hypothermia in multisystem trauma.
Fukudome EY, Alam HB
Crit Care Med 2009 Jul;37(7 Suppl):S265-72. doi: 10.1097/CCM.0b013e3181aa60ac. PMID: 19535957

Clinical prediction guides

Efficacy and Safety of Early Administration of 4-Factor Prothrombin Complex Concentrate in Patients With Trauma at Risk of Massive Transfusion: The PROCOAG Randomized Clinical Trial.
Bouzat P, Charbit J, Abback PS, Huet-Garrigue D, Delhaye N, Leone M, Marcotte G, David JS, Levrat A, Asehnoune K, Pottecher J, Duranteau J, Courvalin E, Adolle A, Sourd D, Bosson JL, Riou B, Gauss T, Payen JF; PROCOAG Study Group
JAMA 2023 Apr 25;329(16):1367-1375. doi: 10.1001/jama.2023.4080. PMID: 36942533Free PMC Article
Artificial intelligence and machine learning for hemorrhagic trauma care.
Peng HT, Siddiqui MM, Rhind SG, Zhang J, da Luz LT, Beckett A
Mil Med Res 2023 Feb 16;10(1):6. doi: 10.1186/s40779-023-00444-0. PMID: 36793066Free PMC Article
Effect of Desmopressin on Platelet Dysfunction During Antiplatelet Therapy: A Systematic Review.
Andersen LK, Hvas AM, Hvas CL
Neurocrit Care 2021 Jun;34(3):1026-1046. Epub 2020 Aug 4 doi: 10.1007/s12028-020-01055-6. PMID: 32748210
The extended autonomic system, dyshomeostasis, and COVID-19.
Goldstein DS
Clin Auton Res 2020 Aug;30(4):299-315. Epub 2020 Jul 22 doi: 10.1007/s10286-020-00714-0. PMID: 32700055Free PMC Article
Thromboelastography and rotational thromboelastometry for the surgical intensivist: A narrative review.
Drumheller BC, Stein DM, Moore LJ, Rizoli SB, Cohen MJ
J Trauma Acute Care Surg 2019 Apr;86(4):710-721. doi: 10.1097/TA.0000000000002206. PMID: 30633093Free PMC Article

Recent systematic reviews

Whole blood transfusion in the treatment of acute hemorrhage, a systematic review and meta-analysis.
van der Horst RA, Rijnhout TWH, Noorman F, Borger van der Burg BLS, van Waes OJF, Verhofstad MHJ, Hoencamp R
J Trauma Acute Care Surg 2023 Aug 1;95(2):256-266. Epub 2023 May 1 doi: 10.1097/TA.0000000000004000. PMID: 37125904
A systematic review and meta-analysis of sample size methodology for traumatic hemorrhage trials.
Ghossein J, Fernando SM, Rochwerg B, Inaba K, Lampron J, Tran A
J Trauma Acute Care Surg 2023 Jun 1;94(6):870-876. Epub 2023 Mar 7 doi: 10.1097/TA.0000000000003944. PMID: 36879398
Impact of resuscitative endovascular balloon occlusion of the aorta (REBOA) in traumatic abdominal and pelvic exsanguination: a systematic review and meta-analysis.
Granieri S, Frassini S, Cimbanassi S, Bonomi A, Paleino S, Lomaglio L, Chierici A, Bruno F, Biondi R, Di Saverio S, Khan M, Cotsoglou C
Eur J Trauma Emerg Surg 2022 Oct;48(5):3561-3574. Epub 2022 Mar 20 doi: 10.1007/s00068-022-01955-6. PMID: 35307763
Effect of Desmopressin on Platelet Dysfunction During Antiplatelet Therapy: A Systematic Review.
Andersen LK, Hvas AM, Hvas CL
Neurocrit Care 2021 Jun;34(3):1026-1046. Epub 2020 Aug 4 doi: 10.1007/s12028-020-01055-6. PMID: 32748210
Pediatric Massive Transfusion: A Systematic Review.
Maw G, Furyk C
Pediatr Emerg Care 2018 Aug;34(8):594-598. doi: 10.1097/PEC.0000000000001570. PMID: 30080793

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