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Splenic Neoplasm

MedGen UID:
21292
•Concept ID:
C0037999
•
Neoplastic Process
Synonyms: Neoplasm, Spleen; Neoplasm, Splenic; Neoplasms, Spleen; Neoplasms, Splenic; Spleen Neoplasm; Spleen Neoplasms; Splenic Neoplasms
SNOMED CT: Tumor of spleen (127230005); Neoplasm of spleen (127230005)

Definition

A benign or malignant neoplasm that affects the spleen. Representative examples include hemangioma, lymphoma, splenic involvement by leukemia, and angiosarcoma. [from NCI]

Professional guidelines

PubMed

Marginal Zone Lymphoma: State-of-the-Art Treatment.
Sindel A, Al-Juhaishi T, Yazbeck V
Curr Treat Options Oncol 2019 Dec 5;20(12):90. doi: 10.1007/s11864-019-0687-5. PMID: 31807935
Hairy cell leukemia: 2020 update on diagnosis, risk stratification, and treatment.
Maitre E, Cornet E, Troussard X
Am J Hematol 2019 Dec;94(12):1413-1422. Epub 2019 Oct 31 doi: 10.1002/ajh.25653. PMID: 31591741
2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM).
Habib G, Lancellotti P, Antunes MJ, Bongiorni MG, Casalta JP, Del Zotti F, Dulgheru R, El Khoury G, Erba PA, Iung B, Miro JM, Mulder BJ, Plonska-Gosciniak E, Price S, Roos-Hesselink J, Snygg-Martin U, Thuny F, Tornos Mas P, Vilacosta I, Zamorano JL; ESC Scientific Document Group
Eur Heart J 2015 Nov 21;36(44):3075-3128. Epub 2015 Aug 29 doi: 10.1093/eurheartj/ehv319. PMID: 26320109

Recent clinical studies

Etiology

Clinicopathological features of splenic tumours of lymphoid tissue.
Chen DB, Shen DH, Yang SM, Fang XZ
Pathol Res Pract 2018 Dec;214(12):1952-1958. Epub 2018 Jul 27 doi: 10.1016/j.prp.2018.07.021. PMID: 30087035
Early detection and integral resection are keys to extend survival in patients suffered from primary angiosarcoma of the spleen: A care-compliant case report and literature review.
Chen X, Li H, Wang F, Liu H
Medicine (Baltimore) 2018 Feb;97(5):e9718. doi: 10.1097/MD.0000000000009718. PMID: 29384853Free PMC Article
Inflammatory Pseudotumor-Like Follicular Dendritic Cell Sarcoma of the Spleen: Computed Tomography Imaging Characteristics in 5 Patients.
Li X, Shi Z, You R, Li Y, Cao D, Lin R, Huang X
J Comput Assist Tomogr 2018 May/Jun;42(3):399-404. doi: 10.1097/RCT.0000000000000700. PMID: 29287022
Littoral cell angioma of the spleen: sonographic-pathologic comparison.
Zhang YH, Liu LM, Wang WP, Ding H, Wang XN, Xia HS
J Ultrasound Med 2013 Apr;32(4):691-7. doi: 10.7863/jum.2013.32.4.691. PMID: 23525396
Littoral cell angioma of the spleen: CT features with clinicopathologic comparison.
Levy AD, Abbott RM, Abbondanzo SL
Radiology 2004 Feb;230(2):485-90. doi: 10.1148/radiol.2302030196. PMID: 14752189

Diagnosis

Primary splenic anaplastic variant of diffuse large B-cell lymphoma: a case report.
Ismail S, Ali F, Ajamieh H, Kanaan S, Issa R, Daoud A, Alshehabi Z
J Med Case Rep 2021 May 6;15(1):227. doi: 10.1186/s13256-021-02846-x. PMID: 33952307Free PMC Article
Clinicopathological features of splenic tumours of lymphoid tissue.
Chen DB, Shen DH, Yang SM, Fang XZ
Pathol Res Pract 2018 Dec;214(12):1952-1958. Epub 2018 Jul 27 doi: 10.1016/j.prp.2018.07.021. PMID: 30087035
Early detection and integral resection are keys to extend survival in patients suffered from primary angiosarcoma of the spleen: A care-compliant case report and literature review.
Chen X, Li H, Wang F, Liu H
Medicine (Baltimore) 2018 Feb;97(5):e9718. doi: 10.1097/MD.0000000000009718. PMID: 29384853Free PMC Article
Inflammatory Pseudotumor-Like Follicular Dendritic Cell Sarcoma of the Spleen: Computed Tomography Imaging Characteristics in 5 Patients.
Li X, Shi Z, You R, Li Y, Cao D, Lin R, Huang X
J Comput Assist Tomogr 2018 May/Jun;42(3):399-404. doi: 10.1097/RCT.0000000000000700. PMID: 29287022
Inflammatory pseudotumors of the spleen.
Safran D, Welch J, Rezuke W
Arch Surg 1991 Jul;126(7):904-8. doi: 10.1001/archsurg.1991.01410310114018. PMID: 1854253

Prognosis

Clinicopathological features of splenic tumours of lymphoid tissue.
Chen DB, Shen DH, Yang SM, Fang XZ
Pathol Res Pract 2018 Dec;214(12):1952-1958. Epub 2018 Jul 27 doi: 10.1016/j.prp.2018.07.021. PMID: 30087035
Early detection and integral resection are keys to extend survival in patients suffered from primary angiosarcoma of the spleen: A care-compliant case report and literature review.
Chen X, Li H, Wang F, Liu H
Medicine (Baltimore) 2018 Feb;97(5):e9718. doi: 10.1097/MD.0000000000009718. PMID: 29384853Free PMC Article
Hepatocellular carcinoma in an ectopic liver: CT findings.
Kim KA, Park CM, Kim CH, Choi SY, Park SW, Hong SJ, Seol HY, Cha IH
Eur Radiol 2003 Dec;13 Suppl 4:L45-7. doi: 10.1007/s00330-003-1908-6. PMID: 15018165

Clinical prediction guides

Inflammatory Pseudotumor-Like Follicular Dendritic Cell Sarcoma of the Spleen: Computed Tomography Imaging Characteristics in 5 Patients.
Li X, Shi Z, You R, Li Y, Cao D, Lin R, Huang X
J Comput Assist Tomogr 2018 May/Jun;42(3):399-404. doi: 10.1097/RCT.0000000000000700. PMID: 29287022

Recent systematic reviews

Elevated serum CA 19-9 level associated with a splenic cyst: which is the actual clinical management? Review of the literature.
Bresadola V, Pravisani R, Terrosu G, Risaliti A
Ann Ital Chir 2015 Jan-Feb;86(1):22-9. PMID: 25819406

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