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Ulcerative stomatitis

MedGen UID:
21335
•Concept ID:
C0038367
•
Disease or Syndrome
Synonym: Stomatitis, Ulcerative
SNOMED CT: Ulcerative stomatitis (450005)
 
Monarch Initiative: MONDO:0004848

Definition

Inflammation of the mouth mucosa associated with the presence of ulcers. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUlcerative stomatitis

Professional guidelines

PubMed

Oral lichen planus: A disease or a spectrum of tissue reactions? Types, causes, diagnostic algorhythms, prognosis, management strategies.
Carrozzo M, Porter S, Mercadante V, Fedele S
Periodontol 2000 2019 Jun;80(1):105-125. doi: 10.1111/prd.12260. PMID: 31090143
Chronic ulcerative stomatitis: A comprehensive review and proposal for diagnostic criteria.
Azzi L, Cerati M, Lombardo M, Pellilli M, Croveri F, Maurino V, Tagliabue A, Tettamanti L, Olszewska M
Oral Dis 2019 Sep;25(6):1465-1491. Epub 2019 Jan 6 doi: 10.1111/odi.13001. PMID: 30457193
Comment: revised treatment of ulcerative stomatitis.
Parashos PJ, Bell PL, Poland JM, Dugan WM Jr
Drug Intell Clin Pharm 1985 Feb;19(2):139. PMID: 3971859

Recent clinical studies

Etiology

Oral lichen planus and related lesions. What should we accept based on the available evidence?
González-Moles MÁ, Ramos-García P
Oral Dis 2023 Oct;29(7):2624-2637. Epub 2022 Dec 8 doi: 10.1111/odi.14438. PMID: 36371653
Oral lichen planus: A disease or a spectrum of tissue reactions? Types, causes, diagnostic algorhythms, prognosis, management strategies.
Carrozzo M, Porter S, Mercadante V, Fedele S
Periodontol 2000 2019 Jun;80(1):105-125. doi: 10.1111/prd.12260. PMID: 31090143
Seventeen New Cases of Chronic Ulcerative Stomatitis with Literature Review.
Reddy R, Fitzpatrick SG, Bhattacharyya I, Cohen DM, Islam MN
Head Neck Pathol 2019 Sep;13(3):386-396. Epub 2018 Oct 29 doi: 10.1007/s12105-018-0982-7. PMID: 30374883Free PMC Article
Spectrum of orocutaneous disease associations: Immune-mediated conditions.
Cizenski JD, Michel P, Watson IT, Frieder J, Wilder EG, Wright JM, Menter MA
J Am Acad Dermatol 2017 Nov;77(5):795-806. doi: 10.1016/j.jaad.2017.02.019. PMID: 29029901
Noma in an immunocompromised patient.
Silva IH, Faria AB, Fonseca DD, Aguiar CM, Carvalho AT, Gueiros LA, Leao JC
Gen Dent 2013 Nov-Dec;61(7):e34-6. PMID: 24192747

Diagnosis

Lichenoid Lesions of the Oral Mucosa.
Islam NM, Alramadhan SA
Oral Maxillofac Surg Clin North Am 2023 May;35(2):189-202. Epub 2023 Feb 15 doi: 10.1016/j.coms.2022.10.005. PMID: 36805899
Oral lichen planus: A disease or a spectrum of tissue reactions? Types, causes, diagnostic algorhythms, prognosis, management strategies.
Carrozzo M, Porter S, Mercadante V, Fedele S
Periodontol 2000 2019 Jun;80(1):105-125. doi: 10.1111/prd.12260. PMID: 31090143
Chronic ulcerative stomatitis: A comprehensive review and proposal for diagnostic criteria.
Azzi L, Cerati M, Lombardo M, Pellilli M, Croveri F, Maurino V, Tagliabue A, Tettamanti L, Olszewska M
Oral Dis 2019 Sep;25(6):1465-1491. Epub 2019 Jan 6 doi: 10.1111/odi.13001. PMID: 30457193
Chronic ulcerative stomatitis.
Solomon LW
Oral Dis 2008 Jul;14(5):383-9. doi: 10.1111/j.1601-0825.2008.01446.x. PMID: 18593454
Chronic ulcerative stomatitis.
Wörle B, Wollenberg A, Schaller M, Kunzelmann KH, Plewig G, Meurer M
Br J Dermatol 1997 Aug;137(2):262-5. doi: 10.1046/j.1365-2133.1997.18171898.x. PMID: 9292078

Therapy

Chronic ulcerative stomatitis: A comprehensive review and proposal for diagnostic criteria.
Azzi L, Cerati M, Lombardo M, Pellilli M, Croveri F, Maurino V, Tagliabue A, Tettamanti L, Olszewska M
Oral Dis 2019 Sep;25(6):1465-1491. Epub 2019 Jan 6 doi: 10.1111/odi.13001. PMID: 30457193
Chronic ulcerative stomatitis.
Solomon LW
Oral Dis 2008 Jul;14(5):383-9. doi: 10.1111/j.1601-0825.2008.01446.x. PMID: 18593454
Chronic ulcerative stomatitis: diagnostic and management challenges--four new cases and review of literature.
Islam MN, Cohen DM, Ojha J, Stewart CM, Katz J, Bhattacharyya I
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007 Aug;104(2):194-203. Epub 2007 Jun 7 doi: 10.1016/j.tripleo.2007.02.013. PMID: 17560144
The clinical spectrum of desquamative gingivitis.
Scully C, Porter SR
Semin Cutan Med Surg 1997 Dec;16(4):308-13. doi: 10.1016/s1085-5629(97)80021-1. PMID: 9421223
Chronic ulcerative stomatitis.
Wörle B, Wollenberg A, Schaller M, Kunzelmann KH, Plewig G, Meurer M
Br J Dermatol 1997 Aug;137(2):262-5. doi: 10.1046/j.1365-2133.1997.18171898.x. PMID: 9292078

Prognosis

Oral lichen planus and related lesions. What should we accept based on the available evidence?
González-Moles MÁ, Ramos-García P
Oral Dis 2023 Oct;29(7):2624-2637. Epub 2022 Dec 8 doi: 10.1111/odi.14438. PMID: 36371653
Oral lichen planus: A disease or a spectrum of tissue reactions? Types, causes, diagnostic algorhythms, prognosis, management strategies.
Carrozzo M, Porter S, Mercadante V, Fedele S
Periodontol 2000 2019 Jun;80(1):105-125. doi: 10.1111/prd.12260. PMID: 31090143
Spectrum of orocutaneous disease associations: Immune-mediated conditions.
Cizenski JD, Michel P, Watson IT, Frieder J, Wilder EG, Wright JM, Menter MA
J Am Acad Dermatol 2017 Nov;77(5):795-806. doi: 10.1016/j.jaad.2017.02.019. PMID: 29029901
Cutaneous changes in patients with chronic renal failure on hemodialysis.
Onelmis H, Sener S, Sasmaz S, Ozer A
Cutan Ocul Toxicol 2012 Dec;31(4):286-91. Epub 2012 Feb 15 doi: 10.3109/15569527.2012.657726. PMID: 22335460
Is chronic ulcerative stomatitis an entity? Clinical and immunological findings in 18 cases.
Chorzelski TP, Olszewska M, Jarzabek-Chorzelska M, Jablonska S
Eur J Dermatol 1998 Jun;8(4):261-5. PMID: 9649663

Clinical prediction guides

Chronic Ulcerative Stomatitis (CUS) as an Interdisciplinary Diagnostic Challenge: A Literature Review.
Cichońska D, Komandera D, Mazuś M, Kusiak A
Int J Mol Sci 2022 Nov 9;23(22) doi: 10.3390/ijms232213772. PMID: 36430253Free PMC Article
Cutaneous changes in patients with chronic renal failure on hemodialysis.
Onelmis H, Sener S, Sasmaz S, Ozer A
Cutan Ocul Toxicol 2012 Dec;31(4):286-91. Epub 2012 Feb 15 doi: 10.3109/15569527.2012.657726. PMID: 22335460
Tp63 in oral development, neoplasia, and autoimmunity.
Romano RA, Solomon LW, Sinha S
J Dent Res 2012 Feb;91(2):125-32. Epub 2011 Jun 6 doi: 10.1177/0022034511411302. PMID: 21646640
Chronic ulcerative stomatitis with stratified epithelium-specific antinuclear antibodies.
Lewis JE, Beutner EH, Rostami R, Chorzelski TP
Int J Dermatol 1996 Apr;35(4):272-5. doi: 10.1111/j.1365-4362.1996.tb03000.x. PMID: 8786185
Methotrexate use in juvenile rheumatoid arthritis.
Zubay Fife R
Orthop Nurs 1993 Jan-Feb;12(1):32-6. doi: 10.1097/00006416-199301000-00008. PMID: 8451058

Recent systematic reviews

The 30th birthday of chronic ulcerative stomatitis: A systematic review.
Herzum A, Burlando M, Cozzani E, Parodi A
Int J Immunopathol Pharmacol 2021 Jan-Dec;35:20587384211052437. doi: 10.1177/20587384211052437. PMID: 34666534Free PMC Article
Chronic ulcerative stomatitis: A systematic review of the clinical and microscopic features.
Ferrisse TM, Travassos DC, Rocha AF, Massucato EM, Bufalino A
Med Oral Patol Oral Cir Bucal 2019 Nov 1;24(6):e698-e703. doi: 10.4317/medoral.22213. PMID: 31655827Free PMC Article
Chronic ulcerative stomatitis: A comprehensive review and proposal for diagnostic criteria.
Azzi L, Cerati M, Lombardo M, Pellilli M, Croveri F, Maurino V, Tagliabue A, Tettamanti L, Olszewska M
Oral Dis 2019 Sep;25(6):1465-1491. Epub 2019 Jan 6 doi: 10.1111/odi.13001. PMID: 30457193
Chronic ulcerative stomatitis: diagnostic and management challenges--four new cases and review of literature.
Islam MN, Cohen DM, Ojha J, Stewart CM, Katz J, Bhattacharyya I
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007 Aug;104(2):194-203. Epub 2007 Jun 7 doi: 10.1016/j.tripleo.2007.02.013. PMID: 17560144

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