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Fundic Gland Polyp

MedGen UID:
214715
Concept ID:
C0920184
Neoplastic Process
Synonym: Polyps, fundic gland
SNOMED CT: Fundic gland polyp (447420007)

Definition

The most common gastric polyp in the Western hemisphere. The lesion consists of a localized hyperplasia of the deep epithelial compartment of the oxyntic mucosa, with variable degrees of cystic dilatation. Malignant transformation is the exception. (WHO, 2000) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFundic Gland Polyp

Professional guidelines

PubMed

Castro R, Pimentel-Nunes P, Dinis-Ribeiro M
Best Pract Res Clin Gastroenterol 2017 Aug;31(4):381-387. Epub 2017 Jun 13 doi: 10.1016/j.bpg.2017.06.001. PMID: 28842047
Schmocker RK, Lidor AO
Surg Clin North Am 2017 Apr;97(2):387-403. doi: 10.1016/j.suc.2016.11.011. PMID: 28325193

Recent clinical studies

Etiology

Sakamoto U, Adachi K, Kishi K, Okimoto E, Ishimura N, Miura H, Ishihara S
Intern Med 2023 Oct 1;62(19):2775-2781. Epub 2023 Feb 22 doi: 10.2169/internalmedicine.1265-22. PMID: 36823084Free PMC Article
Orr CE, Beneck D, Jessurun J, Qin L, Tyryshkin K, Yantiss RK, Chen YT
Histopathology 2022 Jan;80(2):314-321. Epub 2021 Oct 13 doi: 10.1111/his.14549. PMID: 34424570
Amarapurkar AD, Kale KM, Naik LP, Shukla AP
Indian J Pathol Microbiol 2021 Jun;64(Supplement):S69-S72. doi: 10.4103/IJPM.IJPM_118_20. PMID: 34135141
Martin FC, Chenevix-Trench G, Yeomans ND
Aliment Pharmacol Ther 2016 Nov;44(9):915-925. Epub 2016 Sep 15 doi: 10.1111/apt.13800. PMID: 27634363
Hongo M, Fujimoto K; Gastric Polyps Study Group
J Gastroenterol 2010 Jun;45(6):618-24. Epub 2010 Feb 23 doi: 10.1007/s00535-010-0207-7. PMID: 20177714

Diagnosis

Orr CE, Beneck D, Jessurun J, Qin L, Tyryshkin K, Yantiss RK, Chen YT
Histopathology 2022 Jan;80(2):314-321. Epub 2021 Oct 13 doi: 10.1111/his.14549. PMID: 34424570
Velázquez-Dohorn ME, López-Durand CF, Gamboa-Domínguez A
Rev Invest Clin 2018;70(1):40-45. doi: 10.24875/RIC.17002430. PMID: 29513301
Castro R, Pimentel-Nunes P, Dinis-Ribeiro M
Best Pract Res Clin Gastroenterol 2017 Aug;31(4):381-387. Epub 2017 Jun 13 doi: 10.1016/j.bpg.2017.06.001. PMID: 28842047
Schmocker RK, Lidor AO
Surg Clin North Am 2017 Apr;97(2):387-403. doi: 10.1016/j.suc.2016.11.011. PMID: 28325193
Matsukawa A, Kurano R, Takemoto T, Kagayama M, Ito T
Pathol Res Pract 2005;200(11-12):817-21. doi: 10.1016/j.prp.2004.10.005. PMID: 15792126

Therapy

Velazquez-Dohorn M, López-Durand CF, Candanedo-González F, Araujo-Villalvazo EA, Gamboa-Domínguez A
Rev Gastroenterol Mex (Engl Ed) 2020 Jan-Mar;85(1):42-47. Epub 2019 May 22 doi: 10.1016/j.rgmx.2019.02.007. PMID: 31126726
Fukuda M, Ishigaki H, Sugimoto M, Mukaisho KI, Matsubara A, Ishida H, Moritani S, Itoh Y, Sugihara H, Andoh A, Ogasawara K, Murakami K, Kushima R
Histopathology 2019 Oct;75(4):537-545. Epub 2019 Aug 2 doi: 10.1111/his.13902. PMID: 31087669
Martin FC, Chenevix-Trench G, Yeomans ND
Aliment Pharmacol Ther 2016 Nov;44(9):915-925. Epub 2016 Sep 15 doi: 10.1111/apt.13800. PMID: 27634363
Hongo M, Fujimoto K; Gastric Polyps Study Group
J Gastroenterol 2010 Jun;45(6):618-24. Epub 2010 Feb 23 doi: 10.1007/s00535-010-0207-7. PMID: 20177714
Pashankar DS, Israel DM
J Pediatr Gastroenterol Nutr 2002 Nov;35(5):658-62. doi: 10.1097/00005176-200211000-00013. PMID: 12454582

Prognosis

Sakamoto U, Adachi K, Kishi K, Okimoto E, Ishimura N, Miura H, Ishihara S
Intern Med 2023 Oct 1;62(19):2775-2781. Epub 2023 Feb 22 doi: 10.2169/internalmedicine.1265-22. PMID: 36823084Free PMC Article
Dutta AK, Uedo N, David D, Chandramohan J, Jain A, Patnayak I, Gupta P, Ayapati BK, Chatterjee K, Jaleel R, Kurien RT, Chowdhury SD, Simon EG, Joseph AJ, Pulimood AB
Indian J Gastroenterol 2022 Dec;41(6):599-609. Epub 2022 Dec 23 doi: 10.1007/s12664-022-01278-9. PMID: 36562941
Xi S, Jing L, Lili W, Tingting L, Jun L, Ming W, Zhiqiang W, Peng J
BMC Gastroenterol 2022 Dec 6;22(1):502. doi: 10.1186/s12876-022-02589-z. PMID: 36474169Free PMC Article
Watanabe K, Nagata N, Nakashima R, Furuhata E, Shimbo T, Kobayakawa M, Sakurai T, Imbe K, Niikura R, Yokoi C, Akiyama J, Uemura N
World J Gastroenterol 2013 Jul 21;19(27):4374-9. doi: 10.3748/wjg.v19.i27.4374. PMID: 23885149Free PMC Article
Hongo M, Fujimoto K; Gastric Polyps Study Group
J Gastroenterol 2010 Jun;45(6):618-24. Epub 2010 Feb 23 doi: 10.1007/s00535-010-0207-7. PMID: 20177714

Clinical prediction guides

Dutta AK, Uedo N, David D, Chandramohan J, Jain A, Patnayak I, Gupta P, Ayapati BK, Chatterjee K, Jaleel R, Kurien RT, Chowdhury SD, Simon EG, Joseph AJ, Pulimood AB
Indian J Gastroenterol 2022 Dec;41(6):599-609. Epub 2022 Dec 23 doi: 10.1007/s12664-022-01278-9. PMID: 36562941
Orr CE, Beneck D, Jessurun J, Qin L, Tyryshkin K, Yantiss RK, Chen YT
Histopathology 2022 Jan;80(2):314-321. Epub 2021 Oct 13 doi: 10.1111/his.14549. PMID: 34424570
Chang CF, Huang TY, Huang HH, Shih YL, Chang WK, Hsieh TY, Wu LS, Chen KW, Lin HH
Medicine (Baltimore) 2020 Oct 9;99(41):e22556. doi: 10.1097/MD.0000000000022556. PMID: 33031301Free PMC Article
Velázquez-Dohorn ME, López-Durand CF, Gamboa-Domínguez A
Rev Invest Clin 2018;70(1):40-45. doi: 10.24875/RIC.17002430. PMID: 29513301
Watanabe K, Nagata N, Nakashima R, Furuhata E, Shimbo T, Kobayakawa M, Sakurai T, Imbe K, Niikura R, Yokoi C, Akiyama J, Uemura N
World J Gastroenterol 2013 Jul 21;19(27):4374-9. doi: 10.3748/wjg.v19.i27.4374. PMID: 23885149Free PMC Article

Recent systematic reviews

Martin FC, Chenevix-Trench G, Yeomans ND
Aliment Pharmacol Ther 2016 Nov;44(9):915-925. Epub 2016 Sep 15 doi: 10.1111/apt.13800. PMID: 27634363

Supplemental Content

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