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Tic

MedGen UID:
21556
Concept ID:
C0040188
Mental or Behavioral Dysfunction
Synonyms: Tic Disorder; Tic Disorders
SNOMED CT: Tic (386783003); Tics (386783003); Tic disorder (568005)

Definition

Disorders characterized by recurrent TICS that may interfere with speech and other activities. Tics are sudden, rapid, nonrhythmic, stereotyped motor movements or vocalizations which may be exacerbated by stress and are generally attenuated during absorbing activities. Tic disorders are distinguished from conditions which feature other types of abnormal movements that may accompany another another condition. (From DSM-IV, 1994) [from MeSH]

Professional guidelines

PubMed

Roessner V, Eichele H, Stern JS, Skov L, Rizzo R, Debes NM, Nagy P, Cavanna AE, Termine C, Ganos C, Münchau A, Szejko N, Cath D, Müller-Vahl KR, Verdellen C, Hartmann A, Rothenberger A, Hoekstra PJ, Plessen KJ
Eur Child Adolesc Psychiatry 2022 Mar;31(3):425-441. Epub 2021 Nov 10 doi: 10.1007/s00787-021-01899-z. PMID: 34757514Free PMC Article
Müller-Vahl KR, Szejko N, Verdellen C, Roessner V, Hoekstra PJ, Hartmann A, Cath DC
Eur Child Adolesc Psychiatry 2022 Mar;31(3):377-382. Epub 2021 Jul 10 doi: 10.1007/s00787-021-01832-4. PMID: 34244849Free PMC Article
Pringsheim T, Okun MS, Müller-Vahl K, Martino D, Jankovic J, Cavanna AE, Woods DW, Robinson M, Jarvie E, Roessner V, Oskoui M, Holler-Managan Y, Piacentini J
Neurology 2019 May 7;92(19):896-906. doi: 10.1212/WNL.0000000000007466. PMID: 31061208Free PMC Article

Recent clinical studies

Etiology

Cahill EP, Doyle A
Curr Opin Obstet Gynecol 2021 Dec 1;33(6):453-457. doi: 10.1097/GCO.0000000000000749. PMID: 34747881
Dempsey N, Rosenthal A, Dabas N, Kropotova Y, Lippman M, Bishopric NH
Breast Cancer Res Treat 2021 Jul;188(1):21-36. Epub 2021 Jun 11 doi: 10.1007/s10549-021-06280-x. PMID: 34115243
Moore EE, Moore HB, Kornblith LZ, Neal MD, Hoffman M, Mutch NJ, Schöchl H, Hunt BJ, Sauaia A
Nat Rev Dis Primers 2021 Apr 29;7(1):30. doi: 10.1038/s41572-021-00264-3. PMID: 33927200Free PMC Article
Osland ST, Steeves TD, Pringsheim T
Cochrane Database Syst Rev 2018 Jun 26;6(6):CD007990. doi: 10.1002/14651858.CD007990.pub3. PMID: 29944175Free PMC Article
Blackburn JS
Semin Pediatr Neurol 2018 Apr;25:25-33. Epub 2017 Dec 20 doi: 10.1016/j.spen.2017.12.003. PMID: 29735114

Diagnosis

Moore EE, Moore HB, Kornblith LZ, Neal MD, Hoffman M, Mutch NJ, Schöchl H, Hunt BJ, Sauaia A
Nat Rev Dis Primers 2021 Apr 29;7(1):30. doi: 10.1038/s41572-021-00264-3. PMID: 33927200Free PMC Article
Singer HS
Continuum (Minneap Minn) 2019 Aug;25(4):936-958. doi: 10.1212/CON.0000000000000752. PMID: 31356288
Petros S
Hamostaseologie 2019 Feb;39(1):20-27. Epub 2019 Jan 31 doi: 10.1055/s-0039-1677853. PMID: 30703820
Bruce MM, Kassam-Adams N, Rogers M, Anderson KM, Sluys KP, Richmond TS
J Trauma Nurs 2018 Mar/Apr;25(2):131-138. doi: 10.1097/JTN.0000000000000356. PMID: 29521782Free PMC Article
Cohen MJ, Christie SA
Crit Care Clin 2017 Jan;33(1):101-118. doi: 10.1016/j.ccc.2016.08.003. PMID: 27894491

Therapy

Farhat LC, Behling E, Landeros-Weisenberger A, Levine JLS, Macul Ferreira de Barros P, Wang Z, Bloch MH
Lancet Child Adolesc Health 2023 Feb;7(2):112-126. Epub 2022 Dec 14 doi: 10.1016/S2352-4642(22)00316-9. PMID: 36528030
Rizzo R, Prato A, Scerbo M, Saia F, Barone R, Curatolo P
Nutrients 2022 Feb 18;14(4) doi: 10.3390/nu14040852. PMID: 35215501Free PMC Article
Cahill EP, Doyle A
Curr Opin Obstet Gynecol 2021 Dec 1;33(6):453-457. doi: 10.1097/GCO.0000000000000749. PMID: 34747881
Osland ST, Steeves TD, Pringsheim T
Cochrane Database Syst Rev 2018 Jun 26;6(6):CD007990. doi: 10.1002/14651858.CD007990.pub3. PMID: 29944175Free PMC Article
Lipner SR, Scher RK
J Dermatolog Treat 2018 Jun;29(4):411-414. Epub 2017 Nov 9 doi: 10.1080/09546634.2017.1395799. PMID: 29057689

Prognosis

Nilles C, Hartmann A, Roze E, Martino D, Pringsheim T
Handb Clin Neurol 2023;196:457-474. doi: 10.1016/B978-0-323-98817-9.00002-8. PMID: 37620085
Dempsey N, Rosenthal A, Dabas N, Kropotova Y, Lippman M, Bishopric NH
Breast Cancer Res Treat 2021 Jul;188(1):21-36. Epub 2021 Jun 11 doi: 10.1007/s10549-021-06280-x. PMID: 34115243
Goldman KJ, DeLeon IG
Behav Modif 2020 Mar;44(2):296-315. Epub 2018 Oct 29 doi: 10.1177/0145445518809046. PMID: 30373380
Bruce MM, Kassam-Adams N, Rogers M, Anderson KM, Sluys KP, Richmond TS
J Trauma Nurs 2018 Mar/Apr;25(2):131-138. doi: 10.1097/JTN.0000000000000356. PMID: 29521782Free PMC Article
Wirtz MR, Baumann HM, Klinkspoor JH, Goslings JC, Juffermans NP
Semin Thromb Hemost 2017 Jun;43(4):375-385. Epub 2017 Apr 1 doi: 10.1055/s-0037-1598057. PMID: 28364737

Clinical prediction guides

Buzzard L, Schreiber M
J Trauma Acute Care Surg 2024 Feb 1;96(2):179-185. Epub 2023 Oct 13 doi: 10.1097/TA.0000000000004170. PMID: 37828662
Gilbert DL, Dubow JS, Cunniff TM, Wanaski SP, Atkinson SD, Mahableshwarkar AR
Pediatrics 2023 Feb 1;151(2) doi: 10.1542/peds.2022-059574. PMID: 36628546
Goldman KJ, DeLeon IG
Behav Modif 2020 Mar;44(2):296-315. Epub 2018 Oct 29 doi: 10.1177/0145445518809046. PMID: 30373380
Yu D, Sul JH, Tsetsos F, Nawaz MS, Huang AY, Zelaya I, Illmann C, Osiecki L, Darrow SM, Hirschtritt ME, Greenberg E, Muller-Vahl KR, Stuhrmann M, Dion Y, Rouleau G, Aschauer H, Stamenkovic M, Schlögelhofer M, Sandor P, Barr CL, Grados M, Singer HS, Nöthen MM, Hebebrand J, Hinney A, King RA, Fernandez TV, Barta C, Tarnok Z, Nagy P, Depienne C, Worbe Y, Hartmann A, Budman CL, Rizzo R, Lyon GJ, McMahon WM, Batterson JR, Cath DC, Malaty IA, Okun MS, Berlin C, Woods DW, Lee PC, Jankovic J, Robertson MM, Gilbert DL, Brown LW, Coffey BJ, Dietrich A, Hoekstra PJ, Kuperman S, Zinner SH, Luðvigsson P, Sæmundsen E, Thorarensen Ó, Atzmon G, Barzilai N, Wagner M, Moessner R, Ophoff R, Pato CN, Pato MT, Knowles JA, Roffman JL, Smoller JW, Buckner RL, Willsey AJ, Tischfield JA, Heiman GA, Stefansson H, Stefansson K, Posthuma D, Cox NJ, Pauls DL, Freimer NB, Neale BM, Davis LK, Paschou P, Coppola G, Mathews CA, Scharf JM; Tourette Association of America International Consortium for Genetics, the Gilles de la Tourette GWAS Replication Initiative, the Tourette International Collaborative Genetics Study, and the Psychiatric Genomics Consortium Tourette Syndrome Working Group
Am J Psychiatry 2019 Mar 1;176(3):217-227. doi: 10.1176/appi.ajp.2018.18070857. PMID: 30818990Free PMC Article
Bruce MM, Kassam-Adams N, Rogers M, Anderson KM, Sluys KP, Richmond TS
J Trauma Nurs 2018 Mar/Apr;25(2):131-138. doi: 10.1097/JTN.0000000000000356. PMID: 29521782Free PMC Article

Recent systematic reviews

Farhat LC, Behling E, Landeros-Weisenberger A, Levine JLS, Macul Ferreira de Barros P, Wang Z, Bloch MH
Lancet Child Adolesc Health 2023 Feb;7(2):112-126. Epub 2022 Dec 14 doi: 10.1016/S2352-4642(22)00316-9. PMID: 36528030
Jafari F, Abbasi P, Rahmati M, Hodhodi T, Kazeminia M
Pediatr Neurol 2022 Dec;137:6-16. Epub 2022 Sep 5 doi: 10.1016/j.pediatrneurol.2022.08.010. PMID: 36182698
Badenoch J, Searle T, Watson I, Cavanna AE
Neurol Sci 2021 Apr;42(4):1311-1323. Epub 2021 Jan 23 doi: 10.1007/s10072-021-05065-w. PMID: 33486621Free PMC Article
Pringsheim T, Holler-Managan Y, Okun MS, Jankovic J, Piacentini J, Cavanna AE, Martino D, Müller-Vahl K, Woods DW, Robinson M, Jarvie E, Roessner V, Oskoui M
Neurology 2019 May 7;92(19):907-915. doi: 10.1212/WNL.0000000000007467. PMID: 31061209Free PMC Article
Osland ST, Steeves TD, Pringsheim T
Cochrane Database Syst Rev 2018 Jun 26;6(6):CD007990. doi: 10.1002/14651858.CD007990.pub3. PMID: 29944175Free PMC Article

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