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Miliary tuberculosis

MedGen UID:
21726
Concept ID:
C0041321
Disease or Syndrome
Synonyms: Miliary Tuberculoses; Miliary Tuberculosis; Tuberculoses, Miliary; Tuberculosis, Miliary
SNOMED CT: MTB - Miliary tuberculosis (47604008); Miliary tuberculosis (47604008)
 
Monarch Initiative: MONDO:0005848

Definition

Clinical disease resulting from hematogenous dissemination of Mycobacterium tuberculosis bacilli. Originally described by the appearance of millet seed-like granulomas in the lungs, its progression from sustained bacteremia to extrapulmonary involvement is suggestive of a poor prognosis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMiliary tuberculosis

Professional guidelines

PubMed

Athimni S, Slouma M, Dhahri R, Gharsallah I, Metoui L, Louzir B
Curr Drug Saf 2022;17(3):235-240. doi: 10.2174/1574886316666211109092354. PMID: 34751125
Garg RK, Rizvi I, Malhotra HS, Uniyal R, Kumar N
Expert Rev Anti Infect Ther 2018 Nov;16(11):813-831. doi: 10.1080/14787210.2018.1540930. PMID: 30359140
Nachiappan AC, Rahbar K, Shi X, Guy ES, Mortani Barbosa EJ Jr, Shroff GS, Ocazionez D, Schlesinger AE, Katz SI, Hammer MM
Radiographics 2017 Jan-Feb;37(1):52-72. doi: 10.1148/rg.2017160032. PMID: 28076011

Recent clinical studies

Etiology

Nachiappan AC, Rahbar K, Shi X, Guy ES, Mortani Barbosa EJ Jr, Shroff GS, Ocazionez D, Schlesinger AE, Katz SI, Hammer MM
Radiographics 2017 Jan-Feb;37(1):52-72. doi: 10.1148/rg.2017160032. PMID: 28076011
Pérez-Jacoiste Asín MA, Fernández-Ruiz M, López-Medrano F, Lumbreras C, Tejido Á, San Juan R, Arrebola-Pajares A, Lizasoain M, Prieto S, Aguado JM
Medicine (Baltimore) 2014 Oct;93(17):236-254. doi: 10.1097/MD.0000000000000119. PMID: 25398060Free PMC Article
Golden MP, Vikram HR
Am Fam Physician 2005 Nov 1;72(9):1761-8. PMID: 16300038
Carrol ED, Clark JE, Cant AJ
Paediatr Respir Rev 2001 Jun;2(2):113-9. doi: 10.1053/prrv.2000.0118. PMID: 12531057
Snider D
Chest 1984 Sep;86(3 Suppl):10S-13S. doi: 10.1378/chest.86.3.10s. PMID: 6380977

Diagnosis

Choe J, Jung KH, Park JH, Kim SH, Kim MY
Medicine (Baltimore) 2021 Feb 26;100(8):e23833. doi: 10.1097/MD.0000000000023833. PMID: 33663042Free PMC Article
Tan RZ, Mohd Nor F, Shafie S, Tan LJ
Forensic Sci Med Pathol 2019 Mar;15(1):151-154. Epub 2018 Oct 6 doi: 10.1007/s12024-018-0026-3. PMID: 30293222
Vélez-Tirado N, Cote-Orozco JE
Pediatr Neurol 2018 Apr;81:51. Epub 2017 Dec 11 doi: 10.1016/j.pediatrneurol.2017.12.004. PMID: 29398165
Sharma SK, Mohan A
Microbiol Spectr 2017 Mar;5(2) doi: 10.1128/microbiolspec.TNMI7-0013-2016. PMID: 28281441
Restrepo CS, Katre R, Mumbower A
Radiol Clin North Am 2016 May;54(3):453-73. doi: 10.1016/j.rcl.2015.12.007. PMID: 27153783

Therapy

Ahmed A, Mohammed S, Sadek M
Am J Trop Med Hyg 2023 Aug 2;109(2):223-224. Epub 2023 Jul 3 doi: 10.4269/ajtmh.23-0083. PMID: 37400066Free PMC Article
Taleuzzaman M, Kumar V
Recent Pat Antiinfect Drug Discov 2017;12(2):138-146. doi: 10.2174/1574891X12666171006104430. PMID: 28990538
Sharma SK, Mohan A
Microbiol Spectr 2017 Mar;5(2) doi: 10.1128/microbiolspec.TNMI7-0013-2016. PMID: 28281441
Liu A, Nicol E, Hu Y, Coates A
Int J Cardiol 2013 Aug 10;167(3):640-5. Epub 2012 Sep 26 doi: 10.1016/j.ijcard.2012.08.009. PMID: 23021600
Carrol ED, Clark JE, Cant AJ
Paediatr Respir Rev 2001 Jun;2(2):113-9. doi: 10.1053/prrv.2000.0118. PMID: 12531057

Prognosis

Chakaya J, Petersen E, Nantanda R, Mungai BN, Migliori GB, Amanullah F, Lungu P, Ntoumi F, Kumarasamy N, Maeurer M, Zumla A
Int J Infect Dis 2022 Nov;124 Suppl 1:S26-S29. Epub 2022 Mar 20 doi: 10.1016/j.ijid.2022.03.011. PMID: 35321845Free PMC Article
Pérez-Jacoiste Asín MA, Fernández-Ruiz M, López-Medrano F, Lumbreras C, Tejido Á, San Juan R, Arrebola-Pajares A, Lizasoain M, Prieto S, Aguado JM
Medicine (Baltimore) 2014 Oct;93(17):236-254. doi: 10.1097/MD.0000000000000119. PMID: 25398060Free PMC Article
Liu A, Nicol E, Hu Y, Coates A
Int J Cardiol 2013 Aug 10;167(3):640-5. Epub 2012 Sep 26 doi: 10.1016/j.ijcard.2012.08.009. PMID: 23021600
Golden MP, Vikram HR
Am Fam Physician 2005 Nov 1;72(9):1761-8. PMID: 16300038
Carrol ED, Clark JE, Cant AJ
Paediatr Respir Rev 2001 Jun;2(2):113-9. doi: 10.1053/prrv.2000.0118. PMID: 12531057

Clinical prediction guides

Dong S, Zhou R, Peng E, He R
Front Cell Infect Microbiol 2022;12:885865. Epub 2022 Jul 11 doi: 10.3389/fcimb.2022.885865. PMID: 35899049Free PMC Article
Pérez-Jacoiste Asín MA, Fernández-Ruiz M, López-Medrano F, Lumbreras C, Tejido Á, San Juan R, Arrebola-Pajares A, Lizasoain M, Prieto S, Aguado JM
Medicine (Baltimore) 2014 Oct;93(17):236-254. doi: 10.1097/MD.0000000000000119. PMID: 25398060Free PMC Article
Sharma SK, Mohan A, Sharma A
Indian J Med Res 2012 May;135(5):703-30. PMID: 22771605Free PMC Article
Kathuria S, Ramesh V
G Ital Dermatol Venereol 2010 Apr;145(2):289-302. PMID: 20467401
Maltezou HC, Spyridis P, Kafetzis DA
Int J Tuberc Lung Dis 2000 May;4(5):414-9. PMID: 10815734

Recent systematic reviews

Alemu A, Bitew ZW, Seid G, Diriba G, Gashu E, Berhe N, Mariam SH, Gumi B
PLoS One 2022;17(11):e0277807. Epub 2022 Nov 28 doi: 10.1371/journal.pone.0277807. PMID: 36441785Free PMC Article
Rajagopala S, Sankari S, Kancherla R, Ramanathan RP, Balalakshmoji D
Sarcoidosis Vasc Diffuse Lung Dis 2020;37(1):53-65. Epub 2020 Mar 15 doi: 10.36141/svdld.v37i1.7837. PMID: 33093769Free PMC Article
Mangtani P, Abubakar I, Ariti C, Beynon R, Pimpin L, Fine PE, Rodrigues LC, Smith PG, Lipman M, Whiting PF, Sterne JA
Clin Infect Dis 2014 Feb;58(4):470-80. Epub 2013 Dec 13 doi: 10.1093/cid/cit790. PMID: 24336911
Abubakar I, Pimpin L, Ariti C, Beynon R, Mangtani P, Sterne JA, Fine PE, Smith PG, Lipman M, Elliman D, Watson JM, Drumright LN, Whiting PF, Vynnycky E, Rodrigues LC
Health Technol Assess 2013 Sep;17(37):1-372, v-vi. doi: 10.3310/hta17370. PMID: 24021245Free PMC Article
Barreto ML, Pereira SM, Ferreira AA
J Pediatr (Rio J) 2006 Jul;82(3 Suppl):S45-54. doi: 10.2223/JPED.1499. PMID: 16826312

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