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Vaginitis

MedGen UID:
21815
•Concept ID:
C0042267
•
Disease or Syndrome
Synonym: Vaginitides
SNOMED CT: Inflammation of vagina (30800001); Vaginitis (30800001)
 
HPO: HP:0030683
Monarch Initiative: MONDO:0002234

Definition

Inflammation of the vagina that can result from a spectrum of conditions that cause vaginal and sometimes vulvar symptoms, such as itching, burning, irritation, odor, and vaginal discharge. [from HPO]

Professional guidelines

PubMed

Evaluation and Treatment of Vulvodynia: State of the Science.
Schlaeger JM, Glayzer JE, Villegas-Downs M, Li H, Glayzer EJ, He Y, Takayama M, Yajima H, Takakura N, Kobak WH, McFarlin BL
J Midwifery Womens Health 2023 Jan;68(1):9-34. Epub 2022 Dec 19 doi: 10.1111/jmwh.13456. PMID: 36533637Free PMC Article
Evaluation and Management of Vaginitis.
Marnach ML, Wygant JN, Casey PM
Mayo Clin Proc 2022 Feb;97(2):347-358. doi: 10.1016/j.mayocp.2021.09.022. PMID: 35120697
Vaginitis: Diagnosis and Treatment.
Paladine HL, Desai UA
Am Fam Physician 2018 Mar 1;97(5):321-329. PMID: 29671516

Recent clinical studies

Etiology

Infectious Vaginitis, Cervicitis, and Pelvic Inflammatory Disease.
Shroff S
Med Clin North Am 2023 Mar;107(2):299-315. Epub 2022 Dec 26 doi: 10.1016/j.mcna.2022.10.009. PMID: 36759099
Vaginal trichomoniasis.
Cenkowski M, Wudel B, Poliquin V
CMAJ 2022 Feb 14;194(6):E217. doi: 10.1503/cmaj.211088. PMID: 35165134Free PMC Article
Infections During Pregnancy.
Leeper C, Lutzkanin A 3rd
Prim Care 2018 Sep;45(3):567-586. Epub 2018 Jul 9 doi: 10.1016/j.pop.2018.05.013. PMID: 30115342
Vaginitis: Diagnosis and Treatment.
Paladine HL, Desai UA
Am Fam Physician 2018 Mar 1;97(5):321-329. PMID: 29671516
Dysuria: Evaluation and Differential Diagnosis in Adults.
Michels TC, Sands JE
Am Fam Physician 2015 Nov 1;92(9):778-86. PMID: 26554471

Diagnosis

Trichomoniasis.
Van Gerwen OT, Opsteen SA, Graves KJ, Muzny CA
Infect Dis Clin North Am 2023 Jun;37(2):245-265. Epub 2023 Mar 31 doi: 10.1016/j.idc.2023.02.001. PMID: 37005163Free PMC Article
Infectious Vaginitis, Cervicitis, and Pelvic Inflammatory Disease.
Shroff S
Med Clin North Am 2023 Mar;107(2):299-315. Epub 2022 Dec 26 doi: 10.1016/j.mcna.2022.10.009. PMID: 36759099
Recent Advances in Presentation, Diagnosis and Treatment for Mixed Vaginitis.
Qi W, Li H, Wang C, Li H, Zhang B, Dong M, Fan A, Han C, Xue F
Front Cell Infect Microbiol 2021;11:759795. Epub 2021 Nov 2 doi: 10.3389/fcimb.2021.759795. PMID: 34796129Free PMC Article
Vaginitis in Nonpregnant Patients: ACOG Practice Bulletin, Number 215.
Obstet Gynecol 2020 Jan;135(1):e1-e17. doi: 10.1097/AOG.0000000000003604. PMID: 31856123
Vaginitis: Diagnosis and Treatment.
Paladine HL, Desai UA
Am Fam Physician 2018 Mar 1;97(5):321-329. PMID: 29671516

Therapy

Vaginitis in Nonpregnant Patients: ACOG Practice Bulletin, Number 215.
Obstet Gynecol 2020 Jan;135(1):e1-e17. doi: 10.1097/AOG.0000000000003604. PMID: 31856123
Antifungal (oral and vaginal) therapy for recurrent vulvovaginal candidiasis: a systematic review protocol.
Lírio J, Giraldo PC, Amaral RL, Sarmento ACA, Costa APF, Gonçalves AK
BMJ Open 2019 May 22;9(5):e027489. doi: 10.1136/bmjopen-2018-027489. PMID: 31122991Free PMC Article
Vaginitis: Diagnosis and Treatment.
Paladine HL, Desai UA
Am Fam Physician 2018 Mar 1;97(5):321-329. PMID: 29671516
Local oestrogen for vaginal atrophy in postmenopausal women.
Lethaby A, Ayeleke RO, Roberts H
Cochrane Database Syst Rev 2016 Aug 31;2016(8):CD001500. doi: 10.1002/14651858.CD001500.pub3. PMID: 27577677Free PMC Article
Vaginal estrogen for genitourinary syndrome of menopause: a systematic review.
Rahn DD, Carberry C, Sanses TV, Mamik MM, Ward RM, Meriwether KV, Olivera CK, Abed H, Balk EM, Murphy M; Society of Gynecologic Surgeons Systematic Review Group
Obstet Gynecol 2014 Dec;124(6):1147-1156. doi: 10.1097/AOG.0000000000000526. PMID: 25415166Free PMC Article

Prognosis

Current patient perspectives of vulvovaginal candidiasis: incidence, symptoms, management and post-treatment outcomes.
Yano J, Sobel JD, Nyirjesy P, Sobel R, Williams VL, Yu Q, Noverr MC, Fidel PL Jr
BMC Womens Health 2019 Mar 29;19(1):48. doi: 10.1186/s12905-019-0748-8. PMID: 30925872Free PMC Article
Vaginitis: Beyond the Basics.
Mills BB
Obstet Gynecol Clin North Am 2017 Jun;44(2):159-177. doi: 10.1016/j.ogc.2017.02.010. PMID: 28499528
Vulvovaginitis: screening for and management of trichomoniasis, vulvovaginal candidiasis, and bacterial vaginosis.
van Schalkwyk J, Yudin MH; INFECTIOUS DISEASE COMMITTEE
J Obstet Gynaecol Can 2015 Mar;37(3):266-274. doi: 10.1016/S1701-2163(15)30316-9. PMID: 26001874
Emphysematous vaginitis.
Lima-Silva J, Vieira-Baptista P, Cavaco-Gomes J, Maia T, Beires J
J Low Genit Tract Dis 2015 Apr;19(2):e43-4. doi: 10.1097/LGT.0000000000000092. PMID: 25551590
Topical antifungal agents.
Ernest JM
Obstet Gynecol Clin North Am 1992 Sep;19(3):587-607. PMID: 1436934

Clinical prediction guides

Diagnosis and Treatment of Sexually Transmitted Infections: A Review.
Tuddenham S, Hamill MM, Ghanem KG
JAMA 2022 Jan 11;327(2):161-172. doi: 10.1001/jama.2021.23487. PMID: 35015033
Aerobic vaginitis: no longer a stranger.
Donders GGG, Bellen G, Grinceviciene S, Ruban K, Vieira-Baptista P
Res Microbiol 2017 Nov-Dec;168(9-10):845-858. Epub 2017 May 11 doi: 10.1016/j.resmic.2017.04.004. PMID: 28502874
Vulvovaginitis: screening for and management of trichomoniasis, vulvovaginal candidiasis, and bacterial vaginosis.
van Schalkwyk J, Yudin MH; INFECTIOUS DISEASE COMMITTEE
J Obstet Gynaecol Can 2015 Mar;37(3):266-274. doi: 10.1016/S1701-2163(15)30316-9. PMID: 26001874
Reliability of diagnosing bacterial vaginosis is improved by a standardized method of gram stain interpretation.
Nugent RP, Krohn MA, Hillier SL
J Clin Microbiol 1991 Feb;29(2):297-301. doi: 10.1128/jcm.29.2.297-301.1991. PMID: 1706728Free PMC Article
Vaginal infection.
Eschenbach DA
Clin Obstet Gynecol 1983 Mar;26(1):186-202. doi: 10.1097/00003081-198303000-00023. PMID: 6340892

Recent systematic reviews

Hyaluronic Acid in Postmenopause Vaginal Atrophy: A Systematic Review.
Dos Santos CCM, Uggioni MLR, Colonetti T, Colonetti L, Grande AJ, Da Rosa MI
J Sex Med 2021 Jan;18(1):156-166. Epub 2020 Dec 5 doi: 10.1016/j.jsxm.2020.10.016. PMID: 33293236
Clinical Recommendation: Vulvovaginitis.
Zuckerman A, Romano M
J Pediatr Adolesc Gynecol 2016 Dec;29(6):673-679. Epub 2016 Sep 21 doi: 10.1016/j.jpag.2016.08.002. PMID: 27969009
Local oestrogen for vaginal atrophy in postmenopausal women.
Lethaby A, Ayeleke RO, Roberts H
Cochrane Database Syst Rev 2016 Aug 31;2016(8):CD001500. doi: 10.1002/14651858.CD001500.pub3. PMID: 27577677Free PMC Article
Candidiasis (vulvovaginal).
Martin Lopez JE
BMJ Clin Evid 2015 Mar 16;2015 PMID: 25775428Free PMC Article
Vaginal estrogen for genitourinary syndrome of menopause: a systematic review.
Rahn DD, Carberry C, Sanses TV, Mamik MM, Ward RM, Meriwether KV, Olivera CK, Abed H, Balk EM, Murphy M; Society of Gynecologic Surgeons Systematic Review Group
Obstet Gynecol 2014 Dec;124(6):1147-1156. doi: 10.1097/AOG.0000000000000526. PMID: 25415166Free PMC Article

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    Related information

    • GTR
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    • GTR(Clinical)
      Clinical tests in GTR
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