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Nephrogenic adenofibroma

MedGen UID:
220424
•Concept ID:
C1266141
•
Neoplastic Process
Synonyms: Metanephric adenofibroma; Metanephric Adenofibroma; metanephric adenofibroma; Nephrogenic Adenofibroma; nephrogenic adenofibroma
SNOMED CT: Nephrogenic adenofibroma (128760004); Metanephric adenofibroma (128760004)
 
Monarch Initiative: MONDO:0002396

Definition

A benign, solitary, and partially cystic neoplasm arising from the kidney. It occurs in children and adults. Presenting symptoms include hematuria and polycythemia. It is characterized by the presence of epithelial nodules embedded in a stroma containing spindle cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNephrogenic adenofibroma

Recent clinical studies

Etiology

The spectrum of metanephric adenofibroma and related lesions: clinicopathologic study of 25 cases from the National Wilms Tumor Study Group Pathology Center.
Arroyo MR, Green DM, Perlman EJ, Beckwith JB, Argani P
Am J Surg Pathol 2001 Apr;25(4):433-44. doi: 10.1097/00000478-200104000-00002. PMID: 11257617
Metanephric stromal tumor: report of 31 cases of a distinctive pediatric renal neoplasm.
Argani P, Beckwith JB
Am J Surg Pathol 2000 Jul;24(7):917-26. doi: 10.1097/00000478-200007000-00003. PMID: 10895814

Diagnosis

The spectrum of metanephric adenofibroma and related lesions: clinicopathologic study of 25 cases from the National Wilms Tumor Study Group Pathology Center.
Arroyo MR, Green DM, Perlman EJ, Beckwith JB, Argani P
Am J Surg Pathol 2001 Apr;25(4):433-44. doi: 10.1097/00000478-200104000-00002. PMID: 11257617
Metanephric stromal tumor: report of 31 cases of a distinctive pediatric renal neoplasm.
Argani P, Beckwith JB
Am J Surg Pathol 2000 Jul;24(7):917-26. doi: 10.1097/00000478-200007000-00003. PMID: 10895814
Adult mesoblastic nephroma.
Daniel L, Lechevallier E, Bouvier C, Coulange C, Pellissier JF
Pathol Res Pract 2000;196(2):135-9. doi: 10.1016/S0344-0338(00)80046-1. PMID: 10707372
Benign adenomatous kidney neoplasms in children with polycythemia: imaging findings.
Comerci SC, Levin TL, Ruzal-Shapiro C, Berdon WE, Beckwith JB, Hibshoosh H, Hurlet-Jensen A, Sitarz AL
Radiology 1996 Jan;198(1):265-8. doi: 10.1148/radiology.198.1.8539391. PMID: 8539391
Nephrogenic adenofibroma. A novel kidney tumor of young people.
Hennigar RA, Beckwith JB
Am J Surg Pathol 1992 Apr;16(4):325-34. PMID: 1373578

Therapy

Nephrogenic adenofibroma in a young child.
Guzman E, Turc-Carel C, Soler C, Pierre C, Chevallier P, Michiels JF
Pathol Res Pract 2000;196(12):853-6. doi: 10.1016/S0344-0338(00)80088-6. PMID: 11156329

Prognosis

Nephrogenic adenofibroma in a young child.
Guzman E, Turc-Carel C, Soler C, Pierre C, Chevallier P, Michiels JF
Pathol Res Pract 2000;196(12):853-6. doi: 10.1016/S0344-0338(00)80088-6. PMID: 11156329
Metanephric stromal tumor: report of 31 cases of a distinctive pediatric renal neoplasm.
Argani P, Beckwith JB
Am J Surg Pathol 2000 Jul;24(7):917-26. doi: 10.1097/00000478-200007000-00003. PMID: 10895814
Nephrogenic adenofibroma. A novel kidney tumor of young people.
Hennigar RA, Beckwith JB
Am J Surg Pathol 1992 Apr;16(4):325-34. PMID: 1373578

Clinical prediction guides

Myoid differentiation in mesoblastic nephroma: clinicopathologic and cytogenetic findings of a rare case.
Guschmann M, Tönnies H, Bührer C, Mau H, Vogel M
J Pediatr Surg 2002 Aug;37(8):E22. doi: 10.1053/jpsu.2002.34498. PMID: 12149722
Nephrogenic adenofibroma in a young child.
Guzman E, Turc-Carel C, Soler C, Pierre C, Chevallier P, Michiels JF
Pathol Res Pract 2000;196(12):853-6. doi: 10.1016/S0344-0338(00)80088-6. PMID: 11156329

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