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Degenerative disorder

MedGen UID:
224837
Concept ID:
C1285162
Disease or Syndrome
Synonyms: Degenerative Disease; Degenerative Disorder
SNOMED CT: Degenerative disorder (362975008)

Definition

A disorder characterized by the progressive loss of function and/or structure of the affected tissues. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDegenerative disorder

Professional guidelines

PubMed

Pang L, Jin H, Lu Z, Xie F, Shen H, Li X, Zhang X, Jiang X, Wu L, Zhang M, Zhang T, Zhai Y, Zhang Y, Guan H, Su J, Li M, Gao J
Adv Healthc Mater 2023 Jul;12(17):e2300315. Epub 2023 Mar 9 doi: 10.1002/adhm.202300315. PMID: 36848378
Figueroa D, Figueroa F, Calvo R
J Am Acad Orthop Surg 2016 Dec;24(12):e184-e192. doi: 10.5435/JAAOS-D-15-00703. PMID: 27855131
Sinusas K
Am Fam Physician 2012 Jan 1;85(1):49-56. PMID: 22230308

Recent clinical studies

Etiology

Liao Q, He J, Tian FF, Bi FF, Huang K
Front Immunol 2022;13:922922. Epub 2022 Jul 15 doi: 10.3389/fimmu.2022.922922. PMID: 35911771Free PMC Article
Ferreras C, Gorito V, Pedro J, Ferreira S, Costa C, Santos Silva R, Castro Correia C
Endokrynol Pol 2021;72(4):353-356. Epub 2021 May 19 doi: 10.5603/EP.a2021.0038. PMID: 34010437
Riboldi GM, Di Fonzo AB
Cells 2019 Apr 19;8(4) doi: 10.3390/cells8040364. PMID: 31010158Free PMC Article
Figueroa D, Figueroa F, Calvo R
J Am Acad Orthop Surg 2016 Dec;24(12):e184-e192. doi: 10.5435/JAAOS-D-15-00703. PMID: 27855131
Sinusas K
Am Fam Physician 2012 Jan 1;85(1):49-56. PMID: 22230308

Diagnosis

Liao Q, He J, Tian FF, Bi FF, Huang K
Front Immunol 2022;13:922922. Epub 2022 Jul 15 doi: 10.3389/fimmu.2022.922922. PMID: 35911771Free PMC Article
McClugage SG, Oakes WJ
J Neurosurg Pediatr 2019 Sep 1;24(3):217-226. doi: 10.3171/2019.5.PEDS18382. PMID: 31473667
Figueroa D, Figueroa F, Calvo R
J Am Acad Orthop Surg 2016 Dec;24(12):e184-e192. doi: 10.5435/JAAOS-D-15-00703. PMID: 27855131
Tosti R, Jennings J, Sewards JM
Am J Med 2013 Apr;126(4):357.e1-6. Epub 2013 Feb 8 doi: 10.1016/j.amjmed.2012.09.018. PMID: 23398951
Sinusas K
Am Fam Physician 2012 Jan 1;85(1):49-56. PMID: 22230308

Therapy

Profeta V, McIntyre K, Wells M, Park C, Lynch DR
Expert Opin Investig Drugs 2023 Jan;32(1):5-16. Epub 2023 Feb 8 doi: 10.1080/13543784.2023.2173063. PMID: 36708320
Liao Q, He J, Tian FF, Bi FF, Huang K
Front Immunol 2022;13:922922. Epub 2022 Jul 15 doi: 10.3389/fimmu.2022.922922. PMID: 35911771Free PMC Article
Nguyen KML, Nguyen DTD
Tech Vasc Interv Radiol 2020 Dec;23(4):100700. Epub 2020 Oct 5 doi: 10.1016/j.tvir.2020.100700. PMID: 33308584
Sinusas K
Am Fam Physician 2012 Jan 1;85(1):49-56. PMID: 22230308
Mahajan A, Verma S, Tandon V
J Assoc Physicians India 2005 Jul;53:634-41. PMID: 16190135

Prognosis

Liao Q, He J, Tian FF, Bi FF, Huang K
Front Immunol 2022;13:922922. Epub 2022 Jul 15 doi: 10.3389/fimmu.2022.922922. PMID: 35911771Free PMC Article
Ureña-Torres P, D'Marco L, Raggi P, García-Moll X, Brandenburg V, Mazzaferro S, Lieber A, Guirado L, Bover J
Nephrol Dial Transplant 2020 Dec 4;35(12):2046-2053. doi: 10.1093/ndt/gfz133. PMID: 31326992
McClugage SG, Oakes WJ
J Neurosurg Pediatr 2019 Sep 1;24(3):217-226. doi: 10.3171/2019.5.PEDS18382. PMID: 31473667
Botha H, Josephs KA
Continuum (Minneap Minn) 2019 Feb;25(1):101-127. doi: 10.1212/CON.0000000000000699. PMID: 30707189Free PMC Article
Winkler J, Thal LJ, Gage FH, Fisher LJ
J Mol Med (Berl) 1998 Jul;76(8):555-67. doi: 10.1007/s001090050250. PMID: 9694432

Clinical prediction guides

Liao Q, He J, Tian FF, Bi FF, Huang K
Front Immunol 2022;13:922922. Epub 2022 Jul 15 doi: 10.3389/fimmu.2022.922922. PMID: 35911771Free PMC Article
Jena A, Taneja S, Rana P, Goyal N, Vaish A, Botchu R, Vaishya R
Skeletal Radiol 2021 Dec;50(12):2349-2363. Epub 2021 Jun 29 doi: 10.1007/s00256-021-03847-z. PMID: 34185124
Saute JAM, Jardim LB
Adv Exp Med Biol 2018;1049:321-348. doi: 10.1007/978-3-319-71779-1_17. PMID: 29427112
Rodic N
Front Biosci (Landmark Ed) 2018 Mar 1;23(9):1680-1686. doi: 10.2741/4666. PMID: 29293456
Armstrong DD
Ment Retard Dev Disabil Res Rev 2002;8(2):72-6. doi: 10.1002/mrdd.10027. PMID: 12112730

Recent systematic reviews

Wu ZX, Ren WX, Wang ZQ
J Orthop Surg Res 2022 Oct 28;17(1):470. doi: 10.1186/s13018-022-03299-8. PMID: 36307827Free PMC Article
Biffi E, Turple Z, Chung J, Biffi A
PLoS One 2022;17(4):e0266974. Epub 2022 Apr 14 doi: 10.1371/journal.pone.0266974. PMID: 35421194Free PMC Article
Agarwal N, Mak C, Bojanic C, To K, Khan W
Cells 2021 Jun 1;10(6) doi: 10.3390/cells10061365. PMID: 34206010Free PMC Article
Wang G, Cao Y, Wu T, Duan C, Wu J, Hu J, Lu H
J Clin Neurosci 2017 Oct;44:89-94. Epub 2017 Jul 19 doi: 10.1016/j.jocn.2017.06.043. PMID: 28734792
Sulsky SI, Carlton L, Bochmann F, Ellegast R, Glitsch U, Hartmann B, Pallapies D, Seidel D, Sun Y
PLoS One 2012;7(2):e31521. Epub 2012 Feb 14 doi: 10.1371/journal.pone.0031521. PMID: 22348095Free PMC Article

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