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Immune system finding

MedGen UID:
224857
•Concept ID:
C1291764
•
Finding
Synonym: Immune System Finding
SNOMED CT: Immune system finding (106182000)

Definition

Symptoms, physical examination results, and/or laboratory test results related to the immune system. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVImmune system finding

Professional guidelines

PubMed

ACVIM consensus statement guidelines on diagnosing and distinguishing low-grade neoplastic from inflammatory lymphocytic chronic enteropathies in cats.
Marsilio S, Freiche V, Johnson E, Leo C, Langerak AW, Peters I, Ackermann MR
J Vet Intern Med 2023 May-Jun;37(3):794-816. Epub 2023 May 2 doi: 10.1111/jvim.16690. PMID: 37130034Free PMC Article
Autoimmune encephalitis: clinical spectrum and management.
Uy CE, Binks S, Irani SR
Pract Neurol 2021 Oct;21(5):412-423. Epub 2021 Jun 9 doi: 10.1136/practneurol-2020-002567. PMID: 34108243Free PMC Article
Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline.
Brahmer JR, Lacchetti C, Schneider BJ, Atkins MB, Brassil KJ, Caterino JM, Chau I, Ernstoff MS, Gardner JM, Ginex P, Hallmeyer S, Holter Chakrabarty J, Leighl NB, Mammen JS, McDermott DF, Naing A, Nastoupil LJ, Phillips T, Porter LD, Puzanov I, Reichner CA, Santomasso BD, Seigel C, Spira A, Suarez-Almazor ME, Wang Y, Weber JS, Wolchok JD, Thompson JA; National Comprehensive Cancer Network
J Clin Oncol 2018 Jun 10;36(17):1714-1768. Epub 2018 Feb 14 doi: 10.1200/JCO.2017.77.6385. PMID: 29442540Free PMC Article

Recent clinical studies

Etiology

Obesity, Inflammation, and Immune System in Osteoarthritis.
Nedunchezhiyan U, Varughese I, Sun AR, Wu X, Crawford R, Prasadam I
Front Immunol 2022;13:907750. Epub 2022 Jul 4 doi: 10.3389/fimmu.2022.907750. PMID: 35860250Free PMC Article
Systemic autoinflammatory disease in adults.
Betrains A, Staels F, Schrijvers R, Meyts I, Humblet-Baron S, De Langhe E, Wouters C, Blockmans D, Vanderschueren S
Autoimmun Rev 2021 Apr;20(4):102774. Epub 2021 Feb 17 doi: 10.1016/j.autrev.2021.102774. PMID: 33609798
The immune contexture and Immunoscore in cancer prognosis and therapeutic efficacy.
Bruni D, Angell HK, Galon J
Nat Rev Cancer 2020 Nov;20(11):662-680. Epub 2020 Aug 4 doi: 10.1038/s41568-020-0285-7. PMID: 32753728
The Sleep-Immune Crosstalk in Health and Disease.
Besedovsky L, Lange T, Haack M
Physiol Rev 2019 Jul 1;99(3):1325-1380. doi: 10.1152/physrev.00010.2018. PMID: 30920354Free PMC Article
Why sleep is important for health: a psychoneuroimmunology perspective.
Irwin MR
Annu Rev Psychol 2015 Jan 3;66:143-72. Epub 2014 Jul 21 doi: 10.1146/annurev-psych-010213-115205. PMID: 25061767Free PMC Article

Diagnosis

Immunometabolic rewiring in tumorigenesis and anti-tumor immunotherapy.
Lian X, Yang K, Li R, Li M, Zuo J, Zheng B, Wang W, Wang P, Zhou S
Mol Cancer 2022 Jan 21;21(1):27. doi: 10.1186/s12943-021-01486-5. PMID: 35062950Free PMC Article
Rheumatoid Arthritis: Pathogenic Roles of Diverse Immune Cells.
Jang S, Kwon EJ, Lee JJ
Int J Mol Sci 2022 Jan 14;23(2) doi: 10.3390/ijms23020905. PMID: 35055087Free PMC Article
The immune contexture and Immunoscore in cancer prognosis and therapeutic efficacy.
Bruni D, Angell HK, Galon J
Nat Rev Cancer 2020 Nov;20(11):662-680. Epub 2020 Aug 4 doi: 10.1038/s41568-020-0285-7. PMID: 32753728
Autophagy and Inflammation.
Matsuzawa-Ishimoto Y, Hwang S, Cadwell K
Annu Rev Immunol 2018 Apr 26;36:73-101. Epub 2017 Nov 16 doi: 10.1146/annurev-immunol-042617-053253. PMID: 29144836
Biomarkers for chronic fatigue.
Klimas NG, Broderick G, Fletcher MA
Brain Behav Immun 2012 Nov;26(8):1202-10. Epub 2012 Jun 23 doi: 10.1016/j.bbi.2012.06.006. PMID: 22732129Free PMC Article

Therapy

The immune contexture and Immunoscore in cancer prognosis and therapeutic efficacy.
Bruni D, Angell HK, Galon J
Nat Rev Cancer 2020 Nov;20(11):662-680. Epub 2020 Aug 4 doi: 10.1038/s41568-020-0285-7. PMID: 32753728
Exercise-induced pain and analgesia? Underlying mechanisms and clinical translation.
Sluka KA, Frey-Law L, Hoeger Bement M
Pain 2018 Sep;159 Suppl 1(Suppl 1):S91-S97. doi: 10.1097/j.pain.0000000000001235. PMID: 30113953Free PMC Article
Mindfulness meditation and the immune system: a systematic review of randomized controlled trials.
Black DS, Slavich GM
Ann N Y Acad Sci 2016 Jun;1373(1):13-24. Epub 2016 Jan 21 doi: 10.1111/nyas.12998. PMID: 26799456Free PMC Article
Obesity, inflammation and the immune system.
de Heredia FP, Gómez-Martínez S, Marcos A
Proc Nutr Soc 2012 May;71(2):332-8. Epub 2012 Mar 20 doi: 10.1017/S0029665112000092. PMID: 22429824
New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1).
Eisenhauer EA, Therasse P, Bogaerts J, Schwartz LH, Sargent D, Ford R, Dancey J, Arbuck S, Gwyther S, Mooney M, Rubinstein L, Shankar L, Dodd L, Kaplan R, Lacombe D, Verweij J
Eur J Cancer 2009 Jan;45(2):228-47. doi: 10.1016/j.ejca.2008.10.026. PMID: 19097774

Prognosis

Rheumatoid Arthritis: Pathogenic Roles of Diverse Immune Cells.
Jang S, Kwon EJ, Lee JJ
Int J Mol Sci 2022 Jan 14;23(2) doi: 10.3390/ijms23020905. PMID: 35055087Free PMC Article
The immune contexture and Immunoscore in cancer prognosis and therapeutic efficacy.
Bruni D, Angell HK, Galon J
Nat Rev Cancer 2020 Nov;20(11):662-680. Epub 2020 Aug 4 doi: 10.1038/s41568-020-0285-7. PMID: 32753728
The Sleep-Immune Crosstalk in Health and Disease.
Besedovsky L, Lange T, Haack M
Physiol Rev 2019 Jul 1;99(3):1325-1380. doi: 10.1152/physrev.00010.2018. PMID: 30920354Free PMC Article
Graft-versus-host disease.
Moreno DF, Cid J
Med Clin (Barc) 2019 Jan 4;152(1):22-28. Epub 2018 Oct 9 doi: 10.1016/j.medcli.2018.07.012. PMID: 30309668
Immunological Rare Diseases.
Baldovino S, Menegatti E, Roccatello D, Sciascia S
Adv Exp Med Biol 2017;1031:497-509. doi: 10.1007/978-3-319-67144-4_26. PMID: 29214588

Clinical prediction guides

The immune contexture and Immunoscore in cancer prognosis and therapeutic efficacy.
Bruni D, Angell HK, Galon J
Nat Rev Cancer 2020 Nov;20(11):662-680. Epub 2020 Aug 4 doi: 10.1038/s41568-020-0285-7. PMID: 32753728
Neutrophil-to-lymphocyte ratio predicts acute appendicitis and distinguishes between complicated and uncomplicated appendicitis: A systematic review and meta-analysis.
Hajibandeh S, Hajibandeh S, Hobbs N, Mansour M
Am J Surg 2020 Jan;219(1):154-163. Epub 2019 Apr 27 doi: 10.1016/j.amjsurg.2019.04.018. PMID: 31056211
MRI and glymphatic system.
Jiang Q
Stroke Vasc Neurol 2019 Jul;4(2):75-77. Epub 2019 Apr 5 doi: 10.1136/svn-2018-000197. PMID: 31338214Free PMC Article
Lymphatic Anatomy.
Hsu MC, Itkin M
Tech Vasc Interv Radiol 2016 Dec;19(4):247-254. Epub 2016 Oct 8 doi: 10.1053/j.tvir.2016.10.003. PMID: 27993319
Introduction.
Itkin M
Tech Vasc Interv Radiol 2016 Dec;19(4):245-246. Epub 2016 Oct 7 doi: 10.1053/j.tvir.2016.10.004. PMID: 27993318

Recent systematic reviews

Bone Marrow Edema: pathogenetic features.
Molfetta L, Florian A, Saviola G, Frediani B
Clin Ter 2022 Sep-Oct;173(5):434-439. doi: 10.7417/CT.2022.2459. PMID: 36155729
Sleep, cerebrospinal fluid, and the glymphatic system: A systematic review.
Chong PLH, Garic D, Shen MD, Lundgaard I, Schwichtenberg AJ
Sleep Med Rev 2022 Feb;61:101572. Epub 2021 Nov 18 doi: 10.1016/j.smrv.2021.101572. PMID: 34902819Free PMC Article
Systematic Review of Safety and Efficacy of Rituximab in Treating Immune-Mediated Disorders.
Kaegi C, Wuest B, Schreiner J, Steiner UC, Vultaggio A, Matucci A, Crowley C, Boyman O
Front Immunol 2019;10:1990. Epub 2019 Sep 6 doi: 10.3389/fimmu.2019.01990. PMID: 31555262Free PMC Article
Pathobiology of Modic changes.
Dudli S, Fields AJ, Samartzis D, Karppinen J, Lotz JC
Eur Spine J 2016 Nov;25(11):3723-3734. Epub 2016 Feb 25 doi: 10.1007/s00586-016-4459-7. PMID: 26914098Free PMC Article
Mindfulness meditation and the immune system: a systematic review of randomized controlled trials.
Black DS, Slavich GM
Ann N Y Acad Sci 2016 Jun;1373(1):13-24. Epub 2016 Jan 21 doi: 10.1111/nyas.12998. PMID: 26799456Free PMC Article

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