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Glomeruloid hemangioma

MedGen UID:
224917
•Concept ID:
C1304511
•
Neoplastic Process
Synonyms: Glomeruloid Hemangioma; glomeruloid hemangioma
SNOMED CT: Glomeruloid hemangioma (403976007)
 
HPO: HP:0031357
Monarch Initiative: MONDO:0003172

Definition

A histologically distinctive, cutaneous, benign vascular tumor that is characterized by a solitary or multiple blue-red papules and histologically resembles renal glomeruli. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGlomeruloid hemangioma

Professional guidelines

PubMed

TAFRO Syndrome That Responded to Prednisolone-only Treatment: Evaluating Changes in IL-6.
Suzuki H, Sano T, Shimasaki Y, Yamaguchi M, Ide T, Arinaga-Hino T, Kuwahara R, Amano K, Oshima K, Nagafuji K, Ida H, Koga H, Torimura T
Intern Med 2022 Oct 1;61(19):2967-2972. Epub 2022 Feb 26 doi: 10.2169/internalmedicine.9160-21. PMID: 35228431Free PMC Article

Recent clinical studies

Etiology

Vascular tumors of the skin: a selective review.
Hunt SJ, Santa Cruz DJ
Semin Diagn Pathol 2004 Aug;21(3):166-218. doi: 10.1053/j.semdp.2005.01.001. PMID: 15912727
Cutaneous vascular proliferation. Part II. Hyperplasias and benign neoplasms.
Requena L, Sangueza OP
J Am Acad Dermatol 1997 Dec;37(6):887-919; quiz 920-2. doi: 10.1016/s0190-9622(97)70065-3. PMID: 9418757

Diagnosis

Glomeruloid Hemangioma in a Patient with TAFRO Syndrome.
Osano K, Hanai S, Takahashi K, Furuya F
Intern Med 2022 Aug 15;61(16):2545-2546. Epub 2022 Feb 1 doi: 10.2169/internalmedicine.8888-21. PMID: 35110490Free PMC Article
Papillary Hemangioma: An Under-Recognized Entity Not to Be Confused With Glomeruloid Hemangioma.
Maloney N, Miller P, Linos K
Am J Dermatopathol 2020 Mar;42(3):211-214. doi: 10.1097/DAD.0000000000001546. PMID: 31592865
Glomeruloid hemangioma and POEMS syndrome.
Hernández Aragüés I, Pulido Pérez A, Ciudad Blanco C, Parra Blanco V, Suárez Fernández R
Actas Dermosifiliogr 2017 Mar;108(2):e15-e19. Epub 2016 May 18 doi: 10.1016/j.ad.2015.10.020. PMID: 27208909
Glomeruloid hemangioma in POEMS syndrome: a report on two cases and a review of the literature.
Jeunon T, Sampaio AL, Caminha RC, Reis CU, Dib C
An Bras Dermatol 2011 Nov-Dec;86(6):1167-73. doi: 10.1590/s0365-05962011000600016. PMID: 22281906
Cutaneous vascular proliferation. Part II. Hyperplasias and benign neoplasms.
Requena L, Sangueza OP
J Am Acad Dermatol 1997 Dec;37(6):887-919; quiz 920-2. doi: 10.1016/s0190-9622(97)70065-3. PMID: 9418757

Therapy

TAFRO Syndrome That Responded to Prednisolone-only Treatment: Evaluating Changes in IL-6.
Suzuki H, Sano T, Shimasaki Y, Yamaguchi M, Ide T, Arinaga-Hino T, Kuwahara R, Amano K, Oshima K, Nagafuji K, Ida H, Koga H, Torimura T
Intern Med 2022 Oct 1;61(19):2967-2972. Epub 2022 Feb 26 doi: 10.2169/internalmedicine.9160-21. PMID: 35228431Free PMC Article
Glomeruloid hemangioma associated with TAFRO syndrome.
Shinozaki-Ushiku A, Higashihara T, Ikemura M, Sato J, Nangaku M, Ushiku T, Fukayama M
Hum Pathol 2018 Dec;82:172-176. Epub 2018 Apr 25 doi: 10.1016/j.humpath.2018.04.011. PMID: 29702119
Glomeruloid hemangioma.
Yuri T, Yamazaki F, Takasu K, Shikata N, Tsubura A
Pathol Int 2008 Jun;58(6):390-5. doi: 10.1111/j.1440-1827.2008.02241.x. PMID: 18477219
Renal involvement in multicentric Castleman disease with glomeruloid hemangioma of skin and plasmacytoma.
Uthup S, Balachandran K, Ammal VA, Abdul Salam R, George J, Nair GM, Leela M
Am J Kidney Dis 2006 Aug;48(2):e17-24. doi: 10.1053/j.ajkd.2006.04.089. PMID: 16860182

Prognosis

A Rare Case of Intraosseous Papillary Hemangioma of the Head and Neck.
Geetha SD, Abdelwahed M, Edelman MC, Buyuk A, Gordon D, Arvind R
Int J Surg Pathol 2024 Apr;32(2):418-421. Epub 2023 Jun 12 doi: 10.1177/10668969231180282. PMID: 37306145
Glomeruloid Hemangioma as a Late Manifestation of POEMS Syndrome.
Moreira Amorim G, Sodré C, Mastrangelo Marinho Falcão E, Fernandes Timbó R, Cuzzi T, Ramos-E-Silva M
Acta Dermatovenerol Croat 2018 Dec;26(4):321-324. PMID: 30665482
Uterine glomeruloid hemangioma in a patient without POEMS syndrome.
Giner F, Compañ A, Monteagudo C
Int J Surg Pathol 2012 Aug;20(4):407-10. Epub 2011 Nov 30 doi: 10.1177/1066896911429297. PMID: 22134630
Glomeruloid hemangioma.
Yuri T, Yamazaki F, Takasu K, Shikata N, Tsubura A
Pathol Int 2008 Jun;58(6):390-5. doi: 10.1111/j.1440-1827.2008.02241.x. PMID: 18477219
Glomeruloid hemangioma--a specific cutaneous marker of POEMS syndrome.
Tsai CY, Lai CH, Chan HL, Kuo Tt
Int J Dermatol 2001 Jun;40(6):403-6. doi: 10.1046/j.1365-4362.2001.01246-2.x. PMID: 11589746

Clinical prediction guides

Glomeruloid Hemangioma as a Late Manifestation of POEMS Syndrome.
Moreira Amorim G, Sodré C, Mastrangelo Marinho Falcão E, Fernandes Timbó R, Cuzzi T, Ramos-E-Silva M
Acta Dermatovenerol Croat 2018 Dec;26(4):321-324. PMID: 30665482
Reactive angioendotheliomatosis of the intestine.
Ogawa K, Tada T, Takeuchi Y, Suenaga M, Suzuki S, Shirai T
Am J Surg Pathol 2004 Feb;28(2):257-61. doi: 10.1097/00000478-200402000-00015. PMID: 15043317

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