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Venereal Tumors, Veterinary

MedGen UID:
22629
•Concept ID:
C0042465
•
Neoplastic Process
Synonyms: Transmissible Venereal Tumor; Transmissible Venereal Tumors; Tumor, Transmissible Venereal; Tumor, Veterinary Venereal; Tumors, Transmissible Venereal; Tumors, Veterinary Venereal; Venereal Tumor, Transmissible; Venereal Tumor, Veterinary; Venereal Tumors, Transmissible; Veterinary Venereal Tumor; Veterinary Venereal Tumors

Definition

Tumors most commonly seen on or near the genitalia. They are venereal, most likely transmitted through transplantation of cells by contact. Metastases have been reported. Spontaneous regression may occur. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVenereal Tumors, Veterinary

Professional guidelines

PubMed

Electrochemotherapy Treatment of Canine Transmissible Venereal Tumors.
Osorio-Morales LF, Pedraza-Ordóñez F
Artif Organs 2017 Dec;41(12):1185. doi: 10.1111/aor.13062. PMID: 29230847
Effective Treatment of Transmissible Venereal Tumors in Dogs with Vincristine and IL2.
DEN Otter W, Hack M, Jacobs JJ, Tan JF, Rozendaal L, VAN Moorselaar RJ
Anticancer Res 2015 Jun;35(6):3385-91. PMID: 26026099
Immunosuppressor control as a modality of cancer treatment: effect of plasma adsorption with Staphylococcus aureus protein A.
Ray PK
Contemp Top Immunobiol 1985;15:147-211. doi: 10.1007/978-1-4684-4931-0_5. PMID: 3161699

Recent clinical studies

Etiology

Effect of vincristine on intraocular pressure and tear fluid oxidative stress biomarkers in canine transmissible venereal tumor.
Keyvanfard G, Cheraghi H, Aryaei Tabar H
Vet Ophthalmol 2024 Mar;27(2):104-113. Epub 2023 May 29 doi: 10.1111/vop.13108. PMID: 37246963
Comparison of serum 25(OH) vitamin D, parathormone and immunity marker concentrations between dogs with transmissible venereal tumour and healthy dogs.
Sadeghian HK, Mohri M
Vet Med Sci 2023 Sep;9(5):2026-2031. Epub 2023 Aug 3 doi: 10.1002/vms3.1235. PMID: 37534440Free PMC Article
What Animal Cancers teach us about Human Biology.
Kattner P, Zeiler K, Herbener VJ, Ferla-Brühl K, Kassubek R, Grunert M, Burster T, Brühl O, Weber AS, Strobel H, Karpel-Massler G, Ott S, Hagedorn A, Tews D, Schulz A, Prasad V, Siegelin MD, Nonnenmacher L, Fischer-Posovszky P, Halatsch ME, Debatin KM, Westhoff MA
Theranostics 2021;11(14):6682-6702. Epub 2021 May 3 doi: 10.7150/thno.56623. PMID: 34093847Free PMC Article

Diagnosis

Effect of vincristine on intraocular pressure and tear fluid oxidative stress biomarkers in canine transmissible venereal tumor.
Keyvanfard G, Cheraghi H, Aryaei Tabar H
Vet Ophthalmol 2024 Mar;27(2):104-113. Epub 2023 May 29 doi: 10.1111/vop.13108. PMID: 37246963
Effective Treatment of Transmissible Venereal Tumors in Dogs with Vincristine and IL2.
DEN Otter W, Hack M, Jacobs JJ, Tan JF, Rozendaal L, VAN Moorselaar RJ
Anticancer Res 2015 Jun;35(6):3385-91. PMID: 26026099
Progress in Fourier transform infrared spectroscopic imaging applied to venereal cancer diagnosis.
Wood BR, Kiupel M, McNaughton D
Vet Pathol 2014 Jan;51(1):224-37. Epub 2013 Sep 5 doi: 10.1177/0300985813501340. PMID: 24009268
Immunohistochemical characterization of canine transmissible venereal tumor.
Mozos E, Méndez A, Gómez-Villamandos JC, Martín De Las Mulas J, Pérez J
Vet Pathol 1996 May;33(3):257-63. doi: 10.1177/030098589603300301. PMID: 8740698

Therapy

Effect of vincristine on intraocular pressure and tear fluid oxidative stress biomarkers in canine transmissible venereal tumor.
Keyvanfard G, Cheraghi H, Aryaei Tabar H
Vet Ophthalmol 2024 Mar;27(2):104-113. Epub 2023 May 29 doi: 10.1111/vop.13108. PMID: 37246963
Effective Treatment of Transmissible Venereal Tumors in Dogs with Vincristine and IL2.
DEN Otter W, Hack M, Jacobs JJ, Tan JF, Rozendaal L, VAN Moorselaar RJ
Anticancer Res 2015 Jun;35(6):3385-91. PMID: 26026099
Adsorption of plasma from tumor-bearing hosts over protein A--containing nonviable Staphylococcus aureus Cowan I: possible mechanism of antitumor reactions.
Ray PK, McLaughlin D, Allen P, Bandyopadhyay S, Idiculla A, Clarke L, Mark R, Rhoads JE Jr, Bassett JG, Cooper DR
J Biol Response Mod 1984;3(3):293-302. PMID: 6379112

Prognosis

Contagious cancer.
Welsh JS
Oncologist 2011;16(1):1-4. Epub 2011 Jan 6 doi: 10.1634/theoncologist.2010-0301. PMID: 21212437Free PMC Article
Feasibility study of particle-assisted laser ablation of brain tumors in orthotopic canine model.
Schwartz JA, Shetty AM, Price RE, Stafford RJ, Wang JC, Uthamanthil RK, Pham K, McNichols RJ, Coleman CL, Payne JD
Cancer Res 2009 Feb 15;69(4):1659-67. Epub 2009 Feb 10 doi: 10.1158/0008-5472.CAN-08-2535. PMID: 19208847

Clinical prediction guides

Contagious cancer.
Welsh JS
Oncologist 2011;16(1):1-4. Epub 2011 Jan 6 doi: 10.1634/theoncologist.2010-0301. PMID: 21212437Free PMC Article
Adsorption of plasma from tumor-bearing hosts over protein A--containing nonviable Staphylococcus aureus Cowan I: possible mechanism of antitumor reactions.
Ray PK, McLaughlin D, Allen P, Bandyopadhyay S, Idiculla A, Clarke L, Mark R, Rhoads JE Jr, Bassett JG, Cooper DR
J Biol Response Mod 1984;3(3):293-302. PMID: 6379112

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