U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tumor Cell Invasion

MedGen UID:
226866
Concept ID:
C1269955
Neoplastic Process
Synonyms: Invasion; Local Tumor Invasion; Tumor Invasion

Definition

The local spread of tumor cells of a malignant neoplasm through infiltration or destruction of adjacent tissue; for epithelial neoplasms, invasion signifies infiltration beneath the epithelial basement membrane. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTumor Cell Invasion

Professional guidelines

PubMed

Pandey N, Anastasiadis P, Carney CP, Kanvinde PP, Woodworth GF, Winkles JA, Kim AJ
Adv Drug Deliv Rev 2022 Sep;188:114415. Epub 2022 Jul 3 doi: 10.1016/j.addr.2022.114415. PMID: 35787387
Zhang Y, Ho SH, Li B, Nie G, Li S
Med Res Rev 2020 May;40(3):1084-1102. Epub 2019 Nov 11 doi: 10.1002/med.21644. PMID: 31709590
Keller S, Schmidt MHH
Int J Mol Sci 2017 Jun 18;18(6) doi: 10.3390/ijms18061295. PMID: 28629170Free PMC Article

Recent clinical studies

Etiology

Meng Y, Huang K, Shi M, Huo Y, Han L, Liu B, Li Y
Int J Mol Sci 2023 Aug 27;24(17) doi: 10.3390/ijms241713295. PMID: 37686101Free PMC Article
Jeong YJ, Knutsdottir H, Shojaeian F, Lerner MG, Wissler MF, Henriet E, Ng T, Datta S, Navarro-Serer B, Chianchiano P, Kinny-Köster B, Zimmerman JW, Stein-O'Brien G, Gaida MM, Eshleman JR, Lin MT, Fertig EJ, Ewald AJ, Bader JS, Wood LD
J Clin Invest 2023 Apr 17;133(8) doi: 10.1172/JCI162054. PMID: 36881486Free PMC Article
Wei Z, Chen J, Zuo F, Guo J, Sun X, Liu D, Liu C
J Ethnopharmacol 2023 Jan 10;300:115748. Epub 2022 Sep 24 doi: 10.1016/j.jep.2022.115748. PMID: 36162545
Ramer R, Hinz B
Adv Pharmacol 2017;80:397-436. Epub 2017 Jun 12 doi: 10.1016/bs.apha.2017.04.002. PMID: 28826542
Wu JS, Sheng SR, Liang XH, Tang YL
Future Oncol 2017 May;13(11):991-1002. Epub 2017 Jan 11 doi: 10.2217/fon-2016-0501. PMID: 28075171

Diagnosis

Lai H, Cheng X, Liu Q, Luo W, Liu M, Zhang M, Miao J, Ji Z, Lin GN, Song W, Zhang L, Bo J, Yang G, Wang J, Gao WQ
Int J Cancer 2021 Dec 15;149(12):2099-2115. Epub 2021 Sep 16 doi: 10.1002/ijc.33794. PMID: 34480339
Locarno CV, Simonelli M, Carenza C, Capucetti A, Stanzani E, Lorenzi E, Persico P, Della Bella S, Passoni L, Mavilio D, Bonecchi R, Locati M, Savino B
Immunobiology 2020 Jan;225(1):151853. Epub 2019 Oct 19 doi: 10.1016/j.imbio.2019.10.002. PMID: 31703822
Feng W, Dean DC, Hornicek FJ, Shi H, Duan Z
Mol Cancer 2019 Aug 13;18(1):124. doi: 10.1186/s12943-019-1049-4. PMID: 31409361Free PMC Article
Thews O, Riemann A
Cancer Metastasis Rev 2019 Jun;38(1-2):113-129. doi: 10.1007/s10555-018-09777-y. PMID: 30607627
Bakker GJ, Andresen V, Hoffman RM, Friedl P
Methods Enzymol 2012;504:109-25. doi: 10.1016/B978-0-12-391857-4.00005-7. PMID: 22264531

Therapy

Goenka A, Khan F, Verma B, Sinha P, Dmello CC, Jogalekar MP, Gangadaran P, Ahn BC
Cancer Commun (Lond) 2023 May;43(5):525-561. Epub 2023 Apr 2 doi: 10.1002/cac2.12416. PMID: 37005490Free PMC Article
Wei Z, Chen J, Zuo F, Guo J, Sun X, Liu D, Liu C
J Ethnopharmacol 2023 Jan 10;300:115748. Epub 2022 Sep 24 doi: 10.1016/j.jep.2022.115748. PMID: 36162545
Rauf A, Abu-Izneid T, Khalil AA, Imran M, Shah ZA, Emran TB, Mitra S, Khan Z, Alhumaydhi FA, Aljohani ASM, Khan I, Rahman MM, Jeandet P, Gondal TA
Molecules 2021 Dec 4;26(23) doi: 10.3390/molecules26237368. PMID: 34885950Free PMC Article
Te Boekhorst V, Friedl P
Adv Cancer Res 2016;132:209-64. Epub 2016 Aug 17 doi: 10.1016/bs.acr.2016.07.005. PMID: 27613134
Pittayapruek P, Meephansan J, Prapapan O, Komine M, Ohtsuki M
Int J Mol Sci 2016 Jun 2;17(6) doi: 10.3390/ijms17060868. PMID: 27271600Free PMC Article

Prognosis

Menju T, Date H
Gen Thorac Cardiovasc Surg 2021 May;69(5):781-789. Epub 2021 Mar 22 doi: 10.1007/s11748-021-01595-4. PMID: 33754237
Ghasemi A, Saeidi J, Azimi-Nejad M, Hashemy SI
Cell Oncol (Dordr) 2019 Jun;42(3):243-260. Epub 2019 Mar 15 doi: 10.1007/s13402-019-00428-0. PMID: 30877623
Thews O, Riemann A
Cancer Metastasis Rev 2019 Jun;38(1-2):113-129. doi: 10.1007/s10555-018-09777-y. PMID: 30607627
Ray A, Cleary MP
Cytokine Growth Factor Rev 2017 Dec;38:80-97. Epub 2017 Nov 11 doi: 10.1016/j.cytogfr.2017.11.002. PMID: 29158066Free PMC Article
Te Boekhorst V, Friedl P
Adv Cancer Res 2016;132:209-64. Epub 2016 Aug 17 doi: 10.1016/bs.acr.2016.07.005. PMID: 27613134

Clinical prediction guides

Vasudevan J, Jiang K, Fernandez JG, Lim CT
Acta Biomater 2023 Jun;163:351-364. Epub 2022 Oct 13 doi: 10.1016/j.actbio.2022.10.016. PMID: 36243367
Bai R, Zhang J, He F, Li Y, Dai P, Huang Z, Han L, Wang Z, Gong Y, Xie C
Commun Biol 2022 Jul 5;5(1):663. doi: 10.1038/s42003-022-03506-6. PMID: 35790819Free PMC Article
Karagiannis GS, Condeelis JS, Oktay MH
Clin Exp Metastasis 2018 Apr;35(4):269-284. Epub 2018 Jan 6 doi: 10.1007/s10585-017-9870-x. PMID: 29307118Free PMC Article
Gilligan KE, Dwyer RM
Int J Mol Sci 2017 May 24;18(6) doi: 10.3390/ijms18061122. PMID: 28538671Free PMC Article
Te Boekhorst V, Friedl P
Adv Cancer Res 2016;132:209-64. Epub 2016 Aug 17 doi: 10.1016/bs.acr.2016.07.005. PMID: 27613134

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...